Abstract:
OBJECTIVE:We determined the effects of losartan and PD 123319 (antagonists of the AT1 and AT2 angiotensin receptors, respectively), and [Sar1, Ala8] ANG II (a relatively peptide antagonist of angiotensin receptors) injected into the paraventricular nucleus (PVN) on water and 3% NaCl intake, and the diuretic, natriuretic, and pressor effects induced by administration of angiotensin II (ANG II) into the medial septal area (MSA) of conscious rats. METHODS:Holtzman rats were used. Animals were anesthetized with tribromoethanol (20 mg) per 100 grams of body weight, ip. A stainless steel guide cannula was implanted into the MSA and PVN. All drugs were injected in 0.5-microl volumes for 10-15 seconds. Seven days after brain surgery, water and 3% NaCl intake, urine and sodium excretion, and arterial blood pressure were measured. RESULTS:Losartan (40 nmol) and [Sar1, Ala8] ANG II (40 nmol) completely eliminated whereas PD 123319 (40 nmol) partially blocked the increase in water and sodium intake and the increase in arterial blood pressure induced by ANG II (10 nmol) injected into the MSA. The PVN administration of PD 123319 and [Sar1, Ala8] ANG II blocked whereas losartan attenuated the diuresis and natriuresis induced by MSA administration of ANG II. CONCLUSION:MSA involvement with PVN on water and sodium homeostasis and arterial pressure modulation utilizing ANGII receptors is suggested.
journal_name
Arq Bras Cardioljournal_title
Arquivos brasileiros de cardiologiaauthors
Saad WA,Camargo LAdoi
10.1590/s0066-782x2003000400004subject
Has Abstractpub_date
2003-04-01 00:00:00pages
396-405issue
4eissn
0066-782Xissn
1678-4170pii
S0066-782X2003000400004journal_volume
80pub_type
杂志文章abstract:BACKGROUND:The high and increasing prevalence of Dilated Cardiomyopathy (DCM) represents a serious public health problem. New technologies are being used aiming at more accurate diagnoses in order to improve therapeutic approach. In this scenario, speckle tracking echocardiography (STE) uses natural myocardial markers ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2012005000086
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To analyze patients operated on in Brazil from May 1968 until June 1993. METHODS:Three patients were transplanted in the historical period of 1968 and 1969. In the modern period from 1984-1993, 380 transplants were performed in 379 patients. These patients were transplanted in 23 services in 20 hospitals. Thes...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:High blood pressure is the major risk factor for cardiovascular disease. Low blood pressure control rates in Latin American populations emphasize the need for gathering evidence on effective therapies. OBJECTIVE:To evaluate the effects of dietary interventions on blood pressure in Latin American populations...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,meta分析,评审
doi:10.5935/abc.20140037
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Although thrombolysis and primary CTA are well-established procedures, they are not administered in a large proportion of the patients with STEMI who arrive to the emergency rooms. OBJECTIVE:Describe initial and final the results in a cohort of STEMI patients METHODS:The study included, from hospital admis...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2009000600009
更新日期:2009-06-01 00:00:00
abstract::The aim of this paper is to review clinical and laboratory features of this unusual pathology and its complications, indicating transcatheter embolization as a first choice for its management. Our case report is of a seven year-old child, with complex pulmonary arteriovenous fistula of the anterior segment of right su...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,评审
doi:
更新日期:1989-07-01 00:00:00
abstract::OBJECTIVE - Angiotensin-converting enzyme inhibitors (ACEIs) have gained importance in preventing or attenuating the process of ventricular remodeling after myocardial infarction. The significance of infarct size in regard to the response to ACEIs, however, is controversial. This study aimed to analyze the effects of ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x1999001000004
更新日期:1999-10-01 00:00:00
abstract::Anticoagulation is the chief problem during pregnancy of women with mechanical prosthetic valves. Many studies have investigated a nonthrombogenic valve. Since 1978 we have used a biological porcine prosthetic valves in 16 pregnancies, 11 patients with regular clinical electrocardiographic, echocardiographic and chest...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:PURPOSE:To analyse the performance of the artificial cardiac stimulation with the VVIR pacemaker whose sensor is adjusted by the variations of the autonomic nervous system in Chagas disease patients with deficiency of the conduction system. METHODS:Forty-seven Chagas disease patients have been studied, 28 male between...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 临床试验,杂志文章
doi:10.1590/s0066-782x1998001200004
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:To verify whether accentuated reductions of left ventricular volume lead to mitral valve prolapse. METHODS:Seven mongrel dogs were bled through the internal jugular vein, the systolic systemic pressure being kept between 100 and 140 mmHg by means of continuous infusion of dopamine; the inferior vena cava vein,...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::A 54-year-old man with Chagas cardiomyopathy that was submitted to a heart transplantation and five months later presented a progressive increase in liver enzymes. Diagnosis of chronic active hepatitis was confirmed by histopathologic studies. A transitory interruption of treatment with azathioprine and the posterior ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::We presented two cases of falsely elevated CK-MB due to the presence of a type 2 macro CK, showed by isoenzymes electrophoresis. The association of this CK-MB falsely elevated with some digestive diseases are frequent. Quantification of CK isoenzymes by electrophoresis could be indicated in those cases in which the cl...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract::Over the last decades the efficacy and safety of bare metal (BMS) and drug eluting stents (DES) have been demonstrated in many different clinical scenarios, leading to their use in more than 75% of the procedures worldwide. Compared to BMS, DES have shown lower rates of angiographic restenosis and target-vessel revasc...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,meta分析,评审
doi:10.1590/s0066-782x2010001100019
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To study electrophysiological characteristics that enable the identification and ablation of sites of chagasic tachycardia. METHODS:Thirty-one patients with chronic Chagas' heart disease and sustained ventricular tachycardia (SVT) underwent electrophysiological study to map and ablate that arrhythmia. Fiftee...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x1999000400006
更新日期:1999-04-01 00:00:00
abstract:PURPOSE:To evaluate the nitroglycerin patches efficacy and tolerability in patients with stable angina pectoris. METHODS:One thousand and five hundred and thirty nine patients with stable angina pectoris, mean age 61.0 +/- 10.3, 891 men and 648 women were prospectively evaluated by five hundred and thirty five special...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,多中心研究
doi:
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:By reducing the specificity associated with loss of information, the influence of attenuation of the breasts is very important in myocardial perfusion studies. However, although several studies have been conducted over the past years, little has been developed to determine accurately the influence of the cha...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2010005000162
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To analyze the frequency and prevalence of congenital heart defects in a tertiary care center for children with heart diseases. METHODS:We carried out an epidemiological assessment of the first medical visit of 4,538 children in a pediatric hospital from January 1995 to December 1997. All patients with conge...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2003000300003
更新日期:2003-03-01 00:00:00
abstract::The management of cardiac implantable electronic devices after death has become a source of controversy. There are no uniform recommendations for such management in Brazil; practices rely exclusively on institutional protocols and regional custom. When the cadaver is sent for cremation, it is recommended to remove the...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 信件
doi:10.36660/abc.20200447
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To determine the value of pericardial biopsy as a complementary exam in the etiology of pericardial effusion. METHODS:We analyzed retrospectively (from 1990 to 1997) 38 patients with pericardial effusion. The age ranged between 3 months and 79 years (mean 41.15 +/- 21.78 years). Pericardial biopsy was performe...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x1998000600003
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation is the most common persistent arrhythmia, and is the main factor that leads to thromboembolism. OBJECTIVE:To investigate the value of left atrial diameter combined with CHA2DS2-VASc score in predicting left atrial/left atrial appendage thrombosis in non-valvular atrial fibrillation. MET...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.36660/abc.20190492
更新日期:2021-01-18 00:00:00
abstract:BACKGROUND:Cardiac tumors are rare, mostly benign with high embolic potential. OBJECTIVES:To correlate the histological type of cardiac masses with their embolic potential, implantation site and long term follow up in patients undergoing surgery. METHODS:Between January 1986 and December 2011, we retrospectively anal...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20140096
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Depression is a common comorbidity in heart failure (HF); however, the mechanisms related to a poorer outcome of depressed patients with HF remain unclear. OBJECTIVE:To evaluate the role of severe depression in the outcome of patients with decompensated HF. METHODS:A total of 43 patients with advanced HF, ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2010005000125
更新日期:2010-12-01 00:00:00
abstract::The study of myocardial contractility, based on the new anatomical concepts that govern cardiac mechanics, represents a promising strategy of analysis of myocardial adaptations related to physical training in the context of post-infarction. We investigated the influence of aerobic training on physical capacity and on ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20180049
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:To study anatomical limitation of coronary angioplasty, as alternative therapy in patients with multivessel disease and submitted to bypass surgery. METHODS:In 380 patients with multivessel disease and submitted to previous coronary bypass surgery, age ranged from 41 to 72 (average = 51) years, being 68% males...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::The authors consider the possibility of using color Doppler of the ductus venosus and the measurement of nuchal translucency as a screening test for alterations in fetal cardiac functions in the first trimester of gestation. Review of the literature suggests that the combination of the ultrasonographic measurement of ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,评审
doi:10.1590/s0066-782x1999000600009
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia in adults, and is encountered in 10-15% of the patients with hyperthyroidism. Unless euthyroidism is restored, pharmacological or electrical cardioversion is controversial in patients with AF who remain hyperthyroid. OBJECTIVE:The aim of this study was ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20160013
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Transvenous lead extraction (TLE) of cardiac implantable electronic devices (CIED) is an uncommon procedure and requires specialized personnel and adequate facilities. OBJECTIVES:To evaluate the effectiveness and safety of the removal of CIED leads and to determine risk factors for surgical complications an...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.36660/abc.20200476
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Serum cystatin C (s-CC), an endogenous marker of kidney function, has also been proposed as a cardiovascular risk marker. However, it is unknown whether it is a direct marker of atherosclerosis, independently of kidney function. OBJECTIVE:The aim of this study was to correlate s-CC with two surrogate marker...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2012005000083
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To evaluate both the frequency of myocardial infarction and coronary atherosclerosis as well as the pathology of the later in necropsied chronic chagasic individuals. METHODS:Systematized gross and light microscopy were performed in hearts, especially at the three main coronary arteries. Eighty-nine hearts wer...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:Heart transplantation is an alternative for individuals with end-stage heart disease. However, episodes of heart rejection (HR) are frequent and increase morbidity and mortality, requiring the use of an accurate non-invasive exam for their diagnosis, since endomyocardial biopsy (EMB) is not a complication-fr...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2012005000099
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:High-sensitivity cardiac troponin I (hs-cTnI) has played an important role in the risk stratification of patients during the in-hospital phase of acute coronary syndrome (ACS), but few studies have determined its role as a long-term prognostic marker in the outpatient setting. OBJECTIVE:To investigate the a...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20180268
更新日期:2019-03-01 00:00:00