Abstract:
:Congenital insensitivity to pain (hereditary sensory and autonomic neuropathy [HSAN] type V) is a rare disorder of pain perception in which pain sensation is absent from birth, with no other neurologic deficits. We report five Saudi patients (three male and two female) age 10 months to 23 years who lacked pain sensation from birth but have normal appreciation of other sensory modalities. They are from four related families who are descended from one grandfather. The patients had sustained many painless injuries resulting in fractures and disfigurement, but otherwise are completely normal.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Karkashan EM,Joharji HS,Al-Harbi NNdoi
10.1046/j.1525-1470.2002.00095.xsubject
Has Abstractpub_date
2002-07-01 00:00:00pages
333-5issue
4eissn
0736-8046issn
1525-1470pii
0095journal_volume
19pub_type
杂志文章abstract:BACKGROUND/OBJECTIVES:Port-wine stains, also known as capillary malformations, are due to dermal vascular ectasia and dilation and are most commonly congenital; however, acquired port-wine stains (APWS) developing later in life have been noted in the literature, most commonly in the context of trauma. METHODS/RESULTS:...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14019
更新日期:2020-01-01 00:00:00
abstract::A case of childhood granulomatous periorificial dermatitis is described. This disorder occurs predominantly in prepubertal black children and is characterized by a monomorphous, papular eruption occurring around the mouth, nose, and eyes. It is benign and self-limited. Treatment may include topical metronidazole in yo...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1996.tb01419.x
更新日期:1996-03-01 00:00:00
abstract::The common manifestations of atopic dermatitis (AD) appear sequentially with involvement of the cheeks in infancy, flexural extremities in childhood, and hands in adulthood. Although less common clinical manifestations are well described, they have not been the subject of epidemiologic studies to describe their preval...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2012.01739.x
更新日期:2012-09-01 00:00:00
abstract::Imatinib mesylate was the first of several tyrosine kinase inhibitors approved for use in the treatment of a number of human cancers. Adverse cutaneous reactions to imatinib are common. Pseudoporphyria has been infrequently reported in adults undergoing imatinib therapy for chronic myeloid leukemia. We present two chi...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12380
更新日期:2014-09-01 00:00:00
abstract::Cutaneous xanthomas develop as a result of lipid deposition in the dermis and may be a manifestation of various systemic diseases. The morphology and anatomic location of xanthomas are often a clue to the underlying cause. Xanthoma striatum palmare (XSP) is classically associated with dysbetalipoproteinemia and rarely...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14225
更新日期:2020-09-01 00:00:00
abstract::A newborn boy presented with a progressively infiltrating and painful congenital ulcerated plaque on the back of his left foot. A partial excision was performed and histopathologic examination confirmed a diagnosis of a plexiform fibrohistiocytic tumor. This rare tumor usually appears in children and adolescents, with...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.13652
更新日期:2018-11-01 00:00:00
abstract::Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (CLOVE) syndrome is a recently described syndrome similar to Proteus syndrome but lacking the progressive or distorting bony overgrowth of Proteus syndrome. We describe a neonate with features of CLOVE syndrome and nevus unius lateris. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2010.01149.x
更新日期:2010-05-01 00:00:00
abstract::Phrynoderma is a rare form of follicular hyperkeratosis associated with deficiencies in vitamins A or C or essential fatty acids. We report a 6-year-old boy with an unusual presentation of phrynoderma, characterized by multiple minute digitate hyperkeratoses associated with hair casts and related to a severe deficienc...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2006.00261.x
更新日期:2006-07-01 00:00:00
abstract::Telangiectasia macularis eruptiva perstans (TMEP) is a form of mastocytosis. It is an uncommon condition, particularly in children. The disorder is characterized by telangiectatic macules and generally has a good prognosis, with little tendency to urticate or cause constitutional symptoms. We report a girl who present...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2000.01750.x
更新日期:2000-05-01 00:00:00
abstract::Montelukast was effective in treating refractory abdominal and urinary symptoms in a child with systemic mastocytosis. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01576.x
更新日期:2012-03-01 00:00:00
abstract::Rat bite fever is a rare but potentially fatal Gram-negative infection that predominantly affects populations with exposure to rats, notably children. The clinical presentation is nonspecific and requires a high threshold of suspicion to elicit a history of rat exposure. We report here a case of a child whose diagnosi...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01561.x
更新日期:2012-11-01 00:00:00
abstract::Two unrelated Hispanic females, ages 4 and 3 years, respectively, each presented with a solitary patch of excessive terminal hair growth in the midline of the neck. This rare form of congenital localized hypertrichosis, known as anterior cervical hypertrichosis, is reported here as an isolated defect with no other und...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2010.01269.x
更新日期:2010-09-01 00:00:00
abstract::Acquired progressive lymphangioma (APL), or benign lymphangioendothelioma, is an unusual entity derived from vascular structures. Clinically and histopathologically it may resemble Kaposi's sarcoma and well-differentiated angiosarcoma, causing a diagnostic problem. We report an individual with APL initially diagnosed ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13283
更新日期:2017-11-01 00:00:00
abstract::Nodular lichen myxedematosus (LM) is a rare disease and is one of the five subtypes of localized LM. It is distinctly characterized by multiple nodules on the trunk and limbs with or without papular lesions. A healthy 6-year-old boy presented with complaints of "knots" on his right chest, upper limb, and thigh for 4 m...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12376
更新日期:2014-11-01 00:00:00
abstract::Early recognition of the hyperlipoproteinemias is a crucial element in preventing premature coronary artery disease. Xanthomas provide a cutaneous marker of the silent, underlying pathology. Identifying them, and understanding their relation to the inherited hyperlipoproteinemias may facilitate early diagnosis of hype...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.1990.tb00275.x
更新日期:1990-09-01 00:00:00
abstract::To describe the characteristics of five pediatric patients with the Meyerson phenomenon associated with congenital melanocytic nevi, five cases were reviewed to retrieve information relating to clinical presentation, treatment and evolution of the eczematous phenomenon and of the nevi. Three of five patients were male...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2009.00931.x
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:The current treatment of keloids includes surgery, intralesional steroids, and radiotherapy, among others. Radiotherapy is not recommended in children due to its effects on growing tissues. Our aim was to study intralesional triamcinilone therapy of keloids in children and analyze the impact of body location...
journal_title:Pediatric dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/pde.12746
更新日期:2016-01-01 00:00:00
abstract::Post-transplantation lymphoproliferative disorder (PTLD) is one of the most common de novo malignancies in patients who receive immunosuppressive therapy after solid organ transplantation. We report a case of a 5-year-old girl who presented with indurated violaceous skin nodules 3.5 years post-liver transplantation, d...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13903
更新日期:2019-09-01 00:00:00
abstract::An adolescent boy whose initial presentation consisted of an asymmetric, nonvesicular rash was eventually diagnosed with dermatitis herpetiformis (DH). Certain factors, including lesions limited to the genitals, an initial biopsy revealing nonspecific findings on microscopy studies, and the absence of characteristic d...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12086
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Rocky Mountain spotted fever (RMSF), a lethal tick-borne illness, is prevalent in the south central United States. Children younger than 10 years old have the greatest risk of fatal outcome from RMSF. The objective of the current study was to review pediatric cases of RMSF seen in the dermatology ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13053
更新日期:2017-03-01 00:00:00
abstract::We hereby report a 2-year-old boy who presented with a peculiar combination of hyperpigmented and hypopigmented skin lesions along the lines of Blaschko, sharply demarcated at the midline, both on the anterior and posterior trunk. Although combinations of hyperpigmented and hypopigmented skin lesions distributed along...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2007.00529.x
更新日期:2007-09-01 00:00:00
abstract::In 1980 a syndrome was first described in two adult males, consisting of macrocephaly, pigmented macules on the glans and shaft of the penis, and hamartomatous intestinal polyps. Since then, 10 additional cases have been identified. Herein, we present two new cases and review the cutaneous manifestations as well as ad...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1988.tb00880.x
更新日期:1988-02-01 00:00:00
abstract::We evaluated two patients with hereditary bullous poikiloderma. Both had acral bullae, generalized poikiloderma with prominent atrophy, and acral keratoses. One patient, with sporadic disease, had, in addition, urethral and subglottic stenoses, webbing of digits, and poor dentition. The other patient, whose disease wa...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.1989.tb01004.x
更新日期:1989-06-01 00:00:00
abstract::Infantile hemangiomas are the most common benign vascular tumors in childhood. Propranolol is the first-line treatment for infantile hemangiomas, but failures may occur. Sirolimus, an mTOR inhibitor, is a promising drug for the treatment of vascular malformations and vascular tumors. We present the case of a child wit...
journal_title:Pediatric dermatology
pub_type:
doi:10.1111/pde.14163
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Cutaneous leishmaniasis (CL) is an emerging uncontrolled tropical parasitic disease in endemic and nonendemic areas with a high prevalence in the pediatric age group. METHOD:A total of 382 individuals from Lebanon, Saudi Arabia, Pakistan, and Syria diagnosed with CL by punch biopsy/scrapings were grouped in...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14195
更新日期:2020-07-01 00:00:00
abstract::A 14-year-old boy presented with extensive capillaritis. Narrow-band ultraviolet B was administered on a thrice-weekly schedule followed by once-a-week maintenance. A favorable response to treatment was seen without any side effects. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2012.01806.x
更新日期:2013-11-01 00:00:00
abstract::PHACE syndrome is characterized by posterior fossa malformations (P), large facial hemangiomas (H), arterial anomalies (A), cardiac anomalies or coarctation of aorta (C), and eye anomalies (E) and has striking female predominance. Endocrine abnormalities have recently been described in these patients, involving the th...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01540.x
更新日期:2012-05-01 00:00:00
abstract::Although topical application of ceramide is effective in the treatment of atopic dermatitis, its effect is transient. Thus, the effect of oral intake of ceramide on atopic dermatitis was studied. Two groups of 25 children with moderate atopic dermatitis, who were allergic to house dust mite took either milk sugar (con...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2006.00268.x
更新日期:2006-07-01 00:00:00
abstract::Bullous mastocytosis (diffuse cutaneous mastocytosis) is a rare form of mast cell disease that begins during the first month of life and causes extensive blisters that mimic scalded skin syndrome or bullous erythema multiforme. Discrete pigmented macules, papules, and nodules are absent and the characteristic leathery...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1984.tb01131.x
更新日期:1984-04-01 00:00:00
abstract::Trichostasis spinulosa is a disorder of the pilosebaceous follicles that may simulate acne open comedones. It is a commonly reported cosmetic annoyance in adults but not children. A review of the literature and a case of trichostasis spinulosa in a 13-year-old black girl with a history of onset at 18 months of age are...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1996.tb00731.x
更新日期:1996-11-01 00:00:00