Vitamin a deficiency phrynoderma associated with chronic giardiasis.

Abstract:

:Phrynoderma is a rare form of follicular hyperkeratosis associated with deficiencies in vitamins A or C or essential fatty acids. We report a 6-year-old boy with an unusual presentation of phrynoderma, characterized by multiple minute digitate hyperkeratoses associated with hair casts and related to a severe deficiency in vitamins A and C complicating a chronic intestinal giardiasis. The lesions responded well to oral vitamins A and C combined with albendazole treatment. Vitamin A deficiency-related phrynoderma is rare in western countries and is usually caused by digestive malabsorption resulting from large intestine resection or pancreatic failure. To our knowledge, this is the first reported instance of phrynoderma related to a chronic intestinal parasitic infection by Giardia intestinalis with intestinal malabsorption as a likely consequence.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Girard C,Dereure O,Blatière V,Guillot B,Bessis D

doi

10.1111/j.1525-1470.2006.00261.x

subject

Has Abstract

pub_date

2006-07-01 00:00:00

pages

346-9

issue

4

eissn

0736-8046

issn

1525-1470

pii

PDE261

journal_volume

23

pub_type

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