Abstract:
:We examined a father and son affected by Ehlers-Danlos syndrome type II. Both patients had micrognathia together with ligament and skin hyperlaxity. The son exhibited complete cleft palate. Ultrastructural studies revealed abnormal collagen fibrils in the dermis of both patients. In the child the most striking alterations consisted of lateral fusion of an enormous number of collagen fibrils giving rise to huge polymorphic collagen masses. In the father's dermis the great majority of collagen fibrils appeared normal; however, lateral fusion of fibrils together with local abnormal collagen aggregation were occasionally seen. In both patients the dermal elastic network was well developed and elastic fibers appeared normal.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Rizzo R,Contri MB,Micali G,Quaglino D,Pavone L,Ronchetti IPdoi
10.1111/j.1525-1470.1987.tb00778.xsubject
Has Abstractpub_date
1987-11-01 00:00:00pages
197-204issue
3eissn
0736-8046issn
1525-1470journal_volume
4pub_type
杂志文章abstract::We report a rare presentation of vulvar lymphangiectasia that developed secondary to gastrointestinal tuberculosis in a teenager, and its spontaneous resolution after anti-tuberculous treatment was completed. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13920
更新日期:2020-01-01 00:00:00
abstract::Midline congenital cervical cleft is an extremely uncommon anomaly of the neck. Fewer than 100 cases have been reported. It is usually described as a cervical scar-like skin defect. We present a case of midline cervical cleft mimicking linear morphea and treated with topical steroids for 2 years. This is an unusual pr...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12021
更新日期:2013-07-01 00:00:00
abstract::Infantile hemangiomas are the most common benign vascular tumors in childhood. Propranolol is the first-line treatment for infantile hemangiomas, but failures may occur. Sirolimus, an mTOR inhibitor, is a promising drug for the treatment of vascular malformations and vascular tumors. We present the case of a child wit...
journal_title:Pediatric dermatology
pub_type:
doi:10.1111/pde.14163
更新日期:2020-07-01 00:00:00
abstract::Early recognition of the hyperlipoproteinemias is a crucial element in preventing premature coronary artery disease. Xanthomas provide a cutaneous marker of the silent, underlying pathology. Identifying them, and understanding their relation to the inherited hyperlipoproteinemias may facilitate early diagnosis of hype...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.1990.tb00275.x
更新日期:1990-09-01 00:00:00
abstract::We report a 10-month-old boy who presented with a giant perianal condyloma acuminatum, and a similar lesion on the neck. These lesions were treated by surgical excision with satisfactory results. This size, extent, and early age of appearance make this case highly unusual. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2009.00968.x
更新日期:2009-07-01 00:00:00
abstract::Although the U.S. pediatric skin care market is a $1.7 billion industry, little is known regarding the usage pattern of skin care products in very young children. We have begun to recognize that common over-the-counter skin care products may have positive or negative effects on skin barrier function. Thus, knowing wha...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12424
更新日期:2014-11-01 00:00:00
abstract::Congenital midline cervical cleft is a rare anomaly of the ventral neck that heretofore has not been reported in the dermatology literature. We present a case of a midline cervical cleft that was diagnosed and managed at an early age. We also review the literature and discuss its clinical and histologic features, trea...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1525-1470.2000.01727.x
更新日期:2000-03-01 00:00:00
abstract::Aplasia cutis congenita (ACC) is characterized by the complete or partial absence of skin at birth, with 85% of cases of ACC involving the scalp vertex. The etiology of ACC is unclear and appears to be multifactorial. We present the case of a 3-month-old boy who presented with a diagnosis of non-scalp ACC affecting ap...
journal_title:Pediatric dermatology
pub_type:
doi:10.1111/pde.14528
更新日期:2021-01-22 00:00:00
abstract::A child born with the harlequin fetus abnormality survived and showed a surprising degree of spontaneous improvement in the first six weeks of life. At this age etretinate was instituted, producing considerable further resolution. The child is now over 2 years old. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1989.tb00821.x
更新日期:1989-09-01 00:00:00
abstract::Over the years, the application and complications of radiofrequency ablation (RFA) in selective fetal reduction for complex pregnancies have been increasingly documented. Despite its rising use in the field of obstetrics and gynecology, the cutaneous complications of RFA have not been commonly reported. Here, we prese...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14350
更新日期:2020-11-01 00:00:00
abstract::Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is an autosomal dominant inherited blistering skin disease characterized by nonscarring blistering and reticulated hyperpigmentation. It is most commonly due to a heterozygous point mutation, P25L, in the nonhelical V1 domain of keratin 5 (KRT5). Here we...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12206
更新日期:2013-09-01 00:00:00
abstract::The epidermal nevus syndrome is a disorder characterized by epidermal nevi and associated neurologic, skeletal, and other abnormalities. We cared for a 3-month-old male with multiple epidermal nevi and severe central nervous system involvement. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.1989.tb00917.x
更新日期:1989-12-01 00:00:00
abstract::In order to assess the clinical characteristics and impact of group A streptococcal infection in children with atopic dermatitis, a retrospective review was performed in children diagnosed with atopic dermatitis who had a skin culture. Culture results and clinical characteristics of those with group A streptococcus we...
journal_title:Pediatric dermatology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1525-1470.2010.01377.x
更新日期:2011-05-01 00:00:00
abstract::We report a case of acral pigmented lesions due to pine tar, a common compound used on baseball bats to improve grip, deposition. The patient presented with an acute concern for a new melanocytic lesion, and dermoscopy revealed large brown globules, not typical of melanocytic neoplasms. We propose that the coupling of...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13773
更新日期:2019-05-01 00:00:00
abstract::Nickel allergic contact dermatitis is the most prevalent allergy in North America, with an incidence of 14.3%. It is on the rise from 10 years ago, when the incidence was 10%. This has been presumed to represent an increased exposure to nickel in the environment-especially in costume jewelry and belt buckles. We exami...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2002.00057.x
更新日期:2002-03-01 00:00:00
abstract::A 3 year-old boy presented to our clinic with a 3-day history of itchy rash involving the face and limbs and recent contact with a caterpillar. A diagnosis of caterpillar dermatitis was suspected. This condition has rarely been reported and may be underestimated in the pediatric population who may suffer more systemic...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14126
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Topical occlusive agents, such as petroleum jelly and silicone oils, kill head lice by coating and blocking its excretory system and are unlikely to induce treatment resistance. Although a popular alternative to neurotoxic pediculicides, their efficacy and safety remain unclear. METHODS:We searched CENTRAL,...
journal_title:Pediatric dermatology
pub_type: 杂志文章,meta分析
doi:10.1111/pde.14016
更新日期:2020-01-01 00:00:00
abstract::Hereditary mucoepithelial dysplasia (HMD) is a rare genodermatosis characterized by nonscarring alopecia, fiery red gums, perineal erythema, and visual impairment. Histologically, dyskeratotic keratinocytes and a small number of desmosomes are the hallmark of the disease. We report on two unrelated patients who presen...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01649.x
更新日期:2012-05-01 00:00:00
abstract::Molluscum contagiosum is a common childhood condition, and although it is self-limited, treatments are often prescribed. Several medications are available, but there is no consensus regarding the optimal choice in the pediatric population. We report a child who underwent potassium hydroxide 5% treatment resulting in s...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14015
更新日期:2020-01-01 00:00:00
abstract::Traumatic tattoos induced by pencil point puncture in children may result in persistent disfigurement if left untreated. The Q-switched ruby laser effectively removes darkly colored cutaneous chromophores with minimal disruption of unaffected skin. We present a young patient with pencil point induced traumatic tattooi...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1997.tb00969.x
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:In recent years propranolol has become the treatment of choice for infantile hemangiomas (IHs). There is broad variation in the approach to propranolol initiation in clinical practice. This retrospective study explored the effectiveness of routine pre-treatment ECG in screening infants being considered for s...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12972
更新日期:2016-11-01 00:00:00
abstract::Lymphangioma circumscriptum is a lymphatic malformation that involves the skin and may extend to subcutaneous tissue and muscle. Treatment of these lesions is challenging. Surgical excision may be performed but recurrence is common. Herein we report a child with a symptomatic lymphangioma circumscriptum that was treat...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2001.1862001.x
更新日期:2001-11-01 00:00:00
abstract::Two sporadic cases of Heck disease in Polish girls were associated with human papillomavirus 13. No other children and nobody from their surroundings had similar lesions. The course of the disease was chronic in both patients. The lesions regressed spontaneously in one girl within several years after some of the papul...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1993.tb00368.x
更新日期:1993-09-01 00:00:00
abstract::Eruptive vellus hair cysts are benign lesions that can be difficult to distinguish from other skin conditions, including molluscum contagiosum and acne vulgaris. Diagnosis can be corroborated with histopathology. We emphasize differing dermoscopy features to help distinguish eruptive vellus hair cysts from molluscum c...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2012.01771.x
更新日期:2012-11-01 00:00:00
abstract::Microcomedonal lesions can be aesthetically and psychologically displeasing. The burden of comedones increases when considering their frequency and demand for time-consuming attention. The objective of the current study was to describe a novel technique to facilitate open microcomedone extraction. The instrumentation ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12978
更新日期:2016-11-01 00:00:00
abstract::Adams-Oliver syndrome is a congenital condition comprising congenital scalp defects and distal limb abnormalities. We report a child with the sporadic form of the disease who had minimal disease expression, illustrating the wide clinical spectrum of the syndrome. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2007.00598.x
更新日期:2008-01-01 00:00:00
abstract::Burns and scalds are relatively common injuries in children. Formation of hypertrophic scars or keloids is feared complications. A 2-year-old girl who spilled a cup of hot coffee onto herself developed widespread hypertrophic scars and beginning keloids on her upper chest, despite application of pressure garments and ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14017
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Loose anagen syndrome (LAS) is a disorder of abnormal anchorage of the hair to the scalp. Its symptoms include an inability to grow hair long and hair that is easily pulled out. METHODS:We conducted a retrospective chart review of patients with LAS over the last 10 years at the Children's Hospita...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12912
更新日期:2016-09-01 00:00:00
abstract::Blue nevi are common skin neoplasms that typically present as asymptomatic solitary papules, although they may rarely occur in an agminated configuration. We describe a case of agminated blue nevus in a segmental facial distribution associated with soft tissue hypertrophy and hypertrichosis in a 16-year-old boy and pr...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.13303
更新日期:2018-01-01 00:00:00
abstract::We report the rare instance of four family members with numerous cutaneous lesions of Leishmania major contracted while on holiday in Algeria. Treatment was successful with oral itraconazole for the children and intralesional sodium stibogluconate for the mother. Cutaneous leishmaniasis should be considered in those w...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2006.00177.x
更新日期:2006-01-01 00:00:00