Stress and the etiology of osteoarthritis.

Abstract:

:Although degenerative joint disease is an old and exceedingly common problem, clinical investigators have not reached a consensus regarding the etiology of this disease. Comparative osteological analysis of the knee, hip, shoulder, and elbow joints of 789 individuals from four human skeletal populations (Black and White Americans, Pueblo Indians, and Alaskan Eskimos) indicates that age of onset, frequency, and location of degenerative changes are directly related to the nature and degree of environmentally associated stress, as reflected by the variable life styles of the populations sampled. Eskimos have the earliest onset and most severe involvement for all four joints studied, the right side is usually more affected than the left, and Blacks are more frequently involved than Whites in the knee, shoulder, and elbow. Functional stress, when constant and severe in nature, becomes the primary focus of degenerative disease, but other background contributing agents such as age, sex, and hormonal influence must not be ignored.

journal_name

Am J Phys Anthropol

authors

Jurman RD

doi

10.1002/ajpa.1330460214

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

353-65

issue

2

eissn

0002-9483

issn

1096-8644

journal_volume

46

pub_type

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