Abstract:
OBJECTIVE:To examine the association of physical fitness with C-reactive protein (CRP) level in children and young adults. METHODS:Subjects (N = 205) aged 6 to 24 years were enrolled in the Columbia University BioMarkers Study (1994-1998). Physical fitness was assessed using a non-effort-dependent treadmill testing protocol (physical work capacity at heart rate of 170 beats per minute). CRP level was measured using a high-sensitivity assay. RESULTS:Subjects were 54% female and 65% of Hispanic origin. Mean fitness level was higher in boys than in girls, but CRP levels did not differ by gender. Fitness level was inversely correlated with CRP (r = -0.22). This relationship was significant in boys (r = -0.32) but not in girls (r = -0.15). After multivariate regression adjustment for age, race/ethnicity, body mass index, and family history of early-onset ischemic heart disease, physical fitness remained inversely associated with CRP level in boys (beta = -0.02; standard error = 0.01). CONCLUSIONS:These findings indicate that physical fitness is inversely related to CRP level in children and that this relationship is more pronounced in boys than in girls.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Isasi CR,Deckelbaum RJ,Tracy RP,Starc TJ,Berglund L,Shea Sdoi
10.1542/peds.111.2.332subject
Has Abstractpub_date
2003-02-01 00:00:00pages
332-8issue
2eissn
0031-4005issn
1098-4275journal_volume
111pub_type
杂志文章,多中心研究相关文献
PEDIATRICS文献大全abstract::The infant rumination syndrome has not been previously reported in a neonatal intensive care setting. We recently managed three infants in our newborn intensive care unit who developed rumination following chronic courses in the unit. The events leading to this condition in each infant are described, as well as the su...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract:OBJECTIVE:Few investigations have assessed the primary care detection of adolescent posttraumatic emotional distress after an injury. We aimed to determine (1) the level of attachment to primary care providers (PCPs) and school providers among this group of high-risk adolescents, (2) the emotional status of this popula...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-1042
更新日期:2006-01-01 00:00:00
abstract::Patients with interleukin 12 (IL-12)p40 or IL-12 receptor β1 (IL12Rβ1) deficiencies are prone to develop infections caused by mycobacteria and salmonella; other infections have only been rarely observed. In this report we describe 2 unrelated patients with complete autosomal recessive IL12Rβ1 deficiency who suffered f...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-2504
更新日期:2010-10-01 00:00:00
abstract::Lymphatic malformations (LMs) are congenital lymphatic lesions that impose significant and costly morbidities on affected patients. Treatment options are limited due to incomplete understanding of LM pathobiology. Expression of an activated β2-adrenergic receptor has been described in LM tissue, suggesting that this p...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-4545
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:To characterize the incidence of, risk factors for, and neonatal morbidity and mortality associated with respiratory depression at birth and neonatal encephalopathy (NE) among term infants in a developing country. METHODS:Data were collected prospectively in 2002-2006 during a community-based trial that enr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-3590
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Children with medical complexity (CMC) comprise only 6% of the pediatric population, account for ∼40% of pediatric health care spending, and provide an important opportunity for cost saving. Savings in this group can have an important impact on pediatric health care costs. The objective of thi...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2019-2401
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:Despite the magnitude of the problem of catheter-associated bloodstream infections (CA-BSIs) in children, relatively little research has been performed to identify effective strategies to reduce these complications. In this study, we aimed to develop and evaluate effective catheter-care practices to reduce pe...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2009-1382
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of 4 months of daily zinc supplementation on the incidence of severe and recurrent diarrhea in children 6 to 30 months of age. METHODS:A double-blind, randomized, placebo-controlled trial was conducted on children who were identified by a door-to-door survey to be aged 6 to 30 months a...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.109.6.e86
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Childhood asthma prevalence doubled from 1980 to 1995 and then increased more slowly from 2001 to 2010. During this second period, racial disparities increased. More recent trends remain to be described. METHODS:We analyzed current asthma prevalence using 2001-2013 National Health Interview Survey data for ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2354
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:The purpose of this work was to identify barriers to physical activity in children with asthma and to compare their customary activity levels, BMI and emotional well-being with that of children with other medical conditions. It was hypothesized that children with asthma would have higher BMI and lower levels...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1846
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Noncigarette tobacco products are increasingly popular among youth, especially cigarette smokers. Understanding multiple tobacco product use is necessary to assess the effects of tobacco products on population health. This study examines multiple tobacco product use and associated risk factors among US youth...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2014-3202
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Rates of adult women receiving contraceptive provision when simultaneously prescribed a known teratogen are alarmingly low. The prevalence of this behavior among pediatric providers and their adolescent patients is unknown. The objective of this study was to describe pediatric provider behavio...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-1454
更新日期:2016-01-01 00:00:00
abstract::Snowmobiles continue to pose a significant risk to children younger than 15 years and adolescents and young adults 15 through 24 years of age. Head injuries remain the leading cause of mortality and serious morbidity, arising largely from snowmobilers colliding, falling, or overturning during operation. Children also ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::A full-term male infant delivered by caesarean section following a prolonged rupture of the amniotic membranes of 30 hours' duration manifested peculiar skin lesions at the time of birth consistent with the healing phase of bullous impetigo. He was colonized with beta-hemolytic Streptococcus group B that was also cult...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine whether risks of impaired cognitive function could be predicted for children or groups of children with adenotonsillar hypertrophy who were suspected of having obstructive sleep-disordered breathing, from historical and polysomnographic variables used separately or i...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-0173
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:Despite the promising preliminary results observed in extremely low birth weight (ELBW) populations, the use of fluconazole to prevent fungal colonization and infection in preterm neonates in the NICU is still an open question and not yet recommended as a standard of care. We have reviewed our 6-year series t...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-2227
更新日期:2006-01-01 00:00:00
abstract::Recently, a 7-month-old, terminally ill Gypsy infant was admitted to a pediatric intensive care unit. Treating this child and her extended family was a challenging experience during which numerous culture-related problems were encountered. The Gypsy approach to acute medical care consisted of the presence of a large e...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-11-01 00:00:00
abstract:OBJECTIVE:Societal and economic shifts have expanded the roles that fathers play in their families. Father involvement is associated with positive cognitive, developmental, and sociobehavioral child outcomes such as improved weight gain in preterm infants, improved breastfeeding rates, higher receptive language skills,...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-1612
更新日期:2006-04-01 00:00:00
abstract::Multiple arterial punctures in the neonate can result in iatrogenic arteriovenous fistula formation. In one case, a 3-month-old infant who had been born prematurely was noted to have physical findings consistent with arteriovenous malformation following approximately 90 arterial blood gas determinations over a 13-week...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1985-07-01 00:00:00
abstract::In addition to occasional autoimmune hemolytic anemia, unexplained iron-deficiency anemia has been reported in childhood Castleman disease (CD). The recent discovery of hepcidin has regenerated the research on iron metabolism. This hormone is a key regulator of iron homeostasis, mainly by inhibiting intestinal iron ab...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1123
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:To further define the clinical spectrum of the disease for pediatric and metabolic specialists, and to suggest that the general pediatrician and pediatric neurologist consider succinic semialdehyde dehydrogenase (SSADH) deficiency in the differential diagnosis of patients with (idiopathic) mental retardation...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.99.4.567
更新日期:1997-04-01 00:00:00
abstract::There is broad recognition of the need for population-based research to assess the safety and efficacy of newborn screening (NBS) for conditions that are not on current panels. However, prospective population-based research poses significant ethical, regulatory, and logistical challenges. In the context of NBS, there ...
journal_title:Pediatrics
pub_type: 杂志文章,实务指引
doi:10.1542/peds.2013-2271
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Nosocomial rotavirus (nRV) infections represent an important part of rotavirus (RV)-associated morbidity. The incidence of nRV influences the estimated total RV disease burden, an important determinant of cost-effectiveness of RV vaccination programs. Our aim is to summarize the existing evide...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1542/peds.2011-2779
更新日期:2012-04-01 00:00:00
abstract::A previously healthy 15-year-old boy presented with 3 months of progressive psychosis, insomnia, back and groin pain, and hyperhidrosis. On examination, the patient was disheveled, agitated, and soaked with sweat, with systolic blood pressure in the 160s and heart rate in the 130s. Aside from occasional auditory and v...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-3786
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Timely provision of developmental services can improve outcomes for children 0 to 3 years old with developmental delays. Early Intervention (EI) provides free developmental services to children under age 3 years; however, data suggests that many children referred to EI never connect to the pro...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-4017
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Many preterm children display school difficulties, which may be mediated by impairment in executive function and memory. OBJECTIVE:To evaluate executive and memory function among adolescents born preterm compared with term controls at 16 years. METHODS:A total of 337 of 437 (77%) adolescents born in 1989 t...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2010-1421
更新日期:2011-03-01 00:00:00
abstract::Hurler and Scheie syndromes, two of the six clinically distinct mucopolysaccharidoses, are deficient in the same lysosomal enzyme, alpha-L-iduronidase. A third group of iduronidase-deficient patients can now be identified during the pediatric years using clinical and radiographic criteria. Based on inferential evidenc...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:NICU patients have characteristics believed to increase their risk for wrong-patient errors; however, little is known about the frequency of wrong-patient errors in the NICU or about effective interventions for preventing these errors. We conducted a quality improvement study to evaluate the frequency of wro...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-2863
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To address the "millennial morbidities," pediatricians must partner with community-based organizations to develop interventions. Little is known about the capacity of the resulting programs for program evaluation or the importance of evaluation in project success and sustainability. The objective of this stu...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-3273
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:Iron deficiency anemia is known to impair cognitive and psychomotor development. The zinc protoporphyrin/heme (ZPP/H) ratio is a simple, accurate, and sensitive laboratory screening test that detects early iron depletion before the onset of anemia. The objective of this work was to evaluate this test in a pri...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.104.3.e37
更新日期:1999-09-01 00:00:00