Abstract：
:After radical surgery for colo-rectal cancer, the prevention of local recurrence and/or distant metastasis, represents the key factor of the active measures adopted by surgeons and oncologists. Recent trends of the research in this field, show that an effective chemotherapy is the goal to achieve. Our review of the literature on this subject, is aimed to make some remarks about the results of the main randomized protocols of adjuvant chemotherapy conducted in recent years, comparing the efficacy of different treatments. We should consider two ways of administering the chemotherapy: the systemic route, the classic one, and the portal route, especially designed to prevent liver metastasis. At the end of our review, we can conclude the following: poly-chemotherapy (MF or MOF) did not show real advantages compared to 5-FU alone the combination of 5-FU + Levamisole, showed an undoubtable efficacy in Dukes' C colorectal cancer the efficacy of intra-portal vein chemotherapy for Dukes' B colorectal cancer, has been proved in one report only, therefore we are waiting for a confirmative answer from the several similar investigations prompted recently. The analysis of such investigations may contribute, in future, to establish new protocols combining chemotherapy with immunotherapy and particularly, systemic chemotherapy with loco-regional one.
journal_name
Ann Ital Chirjournal_title
Annali italiani di chirurgiaauthors
Rea S,Pietroletti R,Simi Msubject
Has Abstractpub_date
1993-03-01 00:00:00pages
207-12issue
2eissn
0003-469Xissn
2239-253Xjournal_volume
64pub_type
杂志文章,评审abstract：BACKGROUND:The extension of lymphadenectomy is a matter of debate in gastric cancer surgery. The purpose of the present study was to analyse our experience on D3 lymphadenectomy in the treatment of gastric cancer with special reference to post-operative morbidity and mortality, incidence of para-aortic nodal metastases...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：:In the last ten years etiology's frequency of non-neoblastic bowel occlusions has changed. Headway against occlusions percentage decreasing due to post-operative stenosis, hernial strangulation, adhesional bridles, etc., mechanical ileus observations increase in percentage round about 20%, as colon acquired diverticul...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：AIM:This study aims to verify if the duration of postoperative ileus (POI), in patients undergoing abdominal surgery, is related to the surgical approach used (open or laparoscopic) or rather to the manipulation of bowel loops. MATERIALS AND METHODS:Ninety patients, undergoing elective colon resection for cancer, were...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2013-09-01 00:00:00
abstract：:The central venous catheterization (CVC) by subclavian vein puncture for total parenteral nutrition (TPN) has a high risk of complications in some situations such as neck or supraclavicular diseases, tracheostomies, costoclavicular deformities and coagulopathies. Surgical CVC approach to the basilic vein is indicated ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：:Malignant ascites is an abnormal accumulation of fluid in the peritoneal cavity of patients with intraperitoneal cancer dissemination. This clinical condition could represent the terminal evolution of a lethal disease and could influence the prognosis, severely impairing the patients' quality of life. Treatment option...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:Neuroendocrine carcinoma cases, more frequent in the GI tract, have rarely been reported in extrapulmonary areas. Neuroendocrine carcinoma of the bladder is one of the malignancies with a poor prognosis, which is expected to cause rapid metastases. In addition, neuroendocrine carcinoma of the bladder constitutes < 1% ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2019-03-04 00:00:00
abstract：:Carcinoma of the pancreas is the fourth leading cause of cancer related death in Western Countries. The 5-year survival for resectable tumors is 15-25%, while patients with unresectable neoplasms survive a median of 7 months. Only 30% of carcinomas of the head of pancreas and 10% of the body and tail are resectable fo...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：OBJECTIVES:Acute hypercalcemia is a serious condition and represents a physician-surgical emergency: the difficulty in setting a precise diagnosis is due to several possibilities that can cause the condition. It is our purpose to critically evaluate the most actual schemes of treatment and the conditions that could fav...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:A case of acute colonic obstruction in an elderly patient is presented, with a brief discussion about peculiar aspects to pseudo-obstruction and particularly chronic idiopathic intestinal pseudo-obstruction (CIIP), in which it was classified by pathologists. Clinical and therapeutic implications of this classification...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2019-05-05 00:00:00
abstract：AIM:We report our experience of carotid artery stenting (CAS) for the endovascular treatment of significant carotid stenosis over 16 years. MATERIALS AND METHODS:Data of all consecutive patients who came for a significant carotid artery stenosis from January 1st 1999 to August 31st 2015 were retrospectively collected ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:The nonparasitic cysts of the spleen are uncommon and their pathogenesis has not been precisely determined. Often asymptomatic, the cysts are recognised during an investigation of the abdomen for other pathological conditions; if present, the symptoms are not specific and mild. The authors report two cases of non para...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
abstract：AIM:Retrospective review of aorto-iliac infections in a single vascular surgery center. METHODS:From a retrospective review of their experience in the last 20 years, the Authors analyze a series of 12 cases of aorto-iliac infection. Prognostic factors, surgical options and results are discussed and compared with the l...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2011-11-01 00:00:00
abstract：:Anal stenosis is a fibrous narrowing of the anal channel. It develops, in most cases, in the aftermath of proctologic surgical procedures with extensive anoderm excision or in the presence of chronic anal inflammation in patients with Crohn Disease. However rare, this condition is thoroughly debilitating for the patie...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:The Authors report their experience in diagnosis and treatment of one case of primary low-grade gastric lymphoma of mucosa associated lymphoid tissue (MALT); recent international literature review. EXPERIMENTAL DESIGN:Complete clinical report. Diagnostic, clinical and prognostic indication, evaluation of eff...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：AIM:Research of a starting point to debate about the possibility of identifying a unique sign of previous DVT. MATERIAL OF STUDY:A retrospective study involving 202 outpatients with venous insufficiency of the lower limbs (CEAP classes C 4/6), classified according to the affected venous district. Patients positive for...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：AIM:This study is a critical review of conservative office treatments of haemorrhoidal disease. MATERIAL OF STUDY:Many are outpatient techniques proposed in current literature; several with small series, anecdotal ones or some ones yet abandoned for excessive morbidity (for example anal divulsion, dilatation and so on...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2011-09-01 00:00:00
abstract：UNLABELLED:The present retrospective study is related to 85 patients with nodular thyroid pathology submitted to surgical therapy. In these patients preoperative cytology, through fine needle biopsy aspiration (FNBA), has been compared with histological examination performed on the surgical specimen. Malignant lesions ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The problem of relationship between obesity and psychological distress is debated in the literature wherein a lot of studies exists with controversial results. The phenomenon of obesity is actually considered with criteria aimed to evaluate almost exclusively the weight excess. Even if such criteria have the advantage...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2005-09-01 00:00:00
abstract：:The gastrointestinal autonomic nerve tumors (GAN tumor) are uncommon stromal tumors of the intestinal tract and retroperitoneum. The distinction of GAN tumors from other gastrointestinal stromal tumors is based on electron microscopic findings. However further study of additional cases is needed to fully characterize ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：AIM:Adrenal gland metastasis are the second most common type of adrenal mass lesions after adenomas and they could be related to numerous malignancies; Literature shows that adrenal metastasis deriving from colorectal cancer are very rare. MATERIAL OF THE STUDY:A 71-year old - male patient, treated two years before wi...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-06-24 00:00:00
abstract：:Thirty youngs and children were submitted to surgical reconstruction of excavated chest. To prevent risk of infections (by Staphylococcus and mixed gram-negative flora) preoperative 100 mg/Kg body weight of cefotaxime was given. In all patients the operative wounds healed regularly. To evaluate cefotaxime level and th...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：BACKGROUND:From the first successful splenectomy performed in 1893 the trend, in the management of splenic injuries has been increasingly toward avoiding splenectomy in favor of splenic preservation, either operatively or nonoperatively. The aim of this study is to evaluate our experience in the management of splenic i...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Elastofibroma is a benign slow-growing neoplasm of soft tissues, originally defined Elastofibroma dorsi because of the typical localization in the connective tissue placed between the bottom corner of the scapula and the chest wall. From 1990 to 2013 at our center, 115 patients underwent elestofibroma surgical removal...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-03-20 00:00:00
abstract：:The development of clinical and histopathological criteria for the diagnosis of Crohn's disease (CD) and ulcerative colitis (UC), pushed the scientists to identify a new category: the indeterminate colitis (CI). This term is used when definitive diagnosis of UC or CD has not been made by colonoscopy, colonic biopsy or...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2006-07-01 00:00:00
abstract：:The diagnosis of incidental thyroid carcinoma in patients submitted to thyroidectomy for a benign disease is quite frequent. A retrospective analysis was performed on 240 patients submitted to surgical intervention in order to establish the incidence of the carcinoma. One hundred sixty five patients (68.75%) were affe...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2010-05-01 00:00:00
abstract：AIM:We describe the case of a 38 year old man, with a story of alcohol abuse, who developed a very painful nodular subcutaneous fat necrosis, fever and polyarthritis, denying any abdominal symptoms due to a pancreatic pseudocyst-inferior vena cava fistula. MATERIAL OF STUDY:The authors discuss the unusual and protract...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:A correlation between the location of mutation in the adenomatous polyposis coli (APC) gene and clinical manifestations of familial adenomatous polyposis (FAP) has repeatedly been reported. Some Authors suggest the use of mutational analysis as a guide to select the best surgical option in FAP patients. Howe...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:21 patients (19 women) who underwent rectal prolapse repair were prospectively studied. At the one year follow-up, 6 of the eleven incontinent patients (54 per cent) regained full continence and while three of the remaining 5 patients improved they still referred occasional imperfection of continence. Resting anal pre...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:The treatment of acute diverticulitis is a matter of debate and has undergone significant changes. Currently the main focus of surgical treatment is a more conservative and less invasive management. AIMS AND METHODS:To focus the role of surgery in the treatment of acute diverticulitis, the Authors have cond...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2019-01-01 00:00:00
abstract：:Superior mesenteric artery syndrome is an uncommon clinical condition. A case of duodenal vascular compression and a review of the literature are reported in order to clarify the pathophysiology of the disease. Diagnostic values of hypotonic duodenography and angiography are emphasized. Although, the significance of l...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
