Abstract:
:Ecological risk assessments for chemical stressors are used to establish linkages between likely exposure concentrations and adverse effects to ecological receptors. At times, it is useful to conduct screening risk assessments to assist in prioritizing or ranking chemicals on the basis of potential hazard and exposure assessment parameters. Ranking of large chemical inventories can provide evidence for focusing research and/or cleanup efforts on specific chemicals of concern. Because of financial and time constraints, data gaps exist, and the risk assessor is left with decisions on which models to use to estimate the parameter of concern. In this review, several methods are presented for using quantitative structure-activity relationships (QSARs) in conducting hazard screening or screening-level risk assessments. The ranking methods described include those related to current regulatory issues associated with chemical inventories from Canada, Europe, and the United States and an example of a screening-level risk assessment conducted on chemicals associated with a watershed in the midwest region of the United States.
journal_name
Environ Toxicol Chemjournal_title
Environmental toxicology and chemistryauthors
Russom CL,Breton RL,Walker JD,Bradbury SPdoi
10.1897/01-194subject
Has Abstractpub_date
2003-08-01 00:00:00pages
1810-21issue
8eissn
0730-7268issn
1552-8618journal_volume
22pub_type
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