Abstract:
:The high incidence of intersex roach (Rutilus rutilus) in some United Kingdom rivers that has been associated with exposure to sewage treatment works (STWs) effluent led us to hypothesize that top predator fish also may be affected by estrogenic chemicals, because they are likely to bioaccumulate lipophilic compounds through a predator-prey relationship. To investigate this possibility, pike (Esox lucius) were sampled both upstream and downstream of STWs and then examined for total estrogenic activity of their bile, as measured using a yeast-based estrogen assay to determine the degree of recent exposure of the pike to estrogens and vitellogenin induction, and for possible disruption of sexual development, as measured using histological analysis of the gonads. No evidence of severe disruption was found in the sampled fish, which came from 16 sampling sites that were representative of English rivers. However, 14% of pike were intersex, of which 15 of 16 showed patches of male germ cells among predominantly female gonadal tissue. The incidence of masculinization was independent of whether the pike had been sampled upstream or downstream of STWs. Although pike are gonochoristic, it is not known if this masculinization of presumptive female pike is normal or, instead, indicative of endocrine disruption. Vitellogenin concentrations were not elevated in male pike at sites either upstream or downstream of STWs. The results suggest that sexual disruption is not common in pike, a fish at the top of the food chain in the freshwaters of England.
journal_name
Environ Toxicol Chemjournal_title
Environmental toxicology and chemistryauthors
Vine E,Shears J,van Aerle R,Tyler CR,Sumpter JPdoi
10.1897/04-447r.1subject
Has Abstractpub_date
2005-06-01 00:00:00pages
1436-43issue
6eissn
0730-7268issn
1552-8618journal_volume
24pub_type
杂志文章abstract::Hydrocarbon-inducible cytochrome P4501A (CYP1A) expression was measured, as ethoxyresorufin-O-deethylase (EROD) activity, in livers of wintering harlequin ducks (Histrionicus histrionicus) captured in areas of Prince William Sound, Alaska, USA, oiled by the 1989 Exxon Valdez spill and in birds from nearby unoiled area...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.129
更新日期:2010-05-01 00:00:00
abstract::Environmental contamination is suggested to contribute to amphibian population declines. However, the effects of a contaminant on a particular amphibian species can differ among populations. The authors investigated the toxic effects of 2 herbicide formulations on different populations and on representative developmen...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3525
更新日期:2017-01-01 00:00:00
abstract::Sediments in urban waterways of Guangzhou, China, were contaminated by a variety of chemicals and showed prevalent toxicity to benthic organisms. A combination of whole-sediment toxicity identification evaluation (TIE) and bioavailability-based extraction was used to identify the causes of sediment toxicity. Of the 6 ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2970
更新日期:2015-08-01 00:00:00
abstract::Herbicide drift may cause adverse effects on natural and semi-natural plant communities, and it has been debated whether the current ecological risk assessments are adequate to protect non-target terrestrial plant species (NTTP). In this study, nine NTTPs with different lifespans (three annual/ six perennial) belongin...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4992
更新日期:2021-01-25 00:00:00
abstract::The influence of seasonal changes in water conditions and parameters on several major pharmacologically active compounds (PhACs) and s-triazine herbicides was assessed in the wastewater and sewage treatment plant (WSTP) effluent as well as the downstream surface water from sites on the Canadian side of the upper Detro...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-571r.1
更新日期:2006-09-01 00:00:00
abstract::The reference method for the Canada-wide standard (CWS) for petroleum hydrocarbons (PHCs) in soil provides laboratories with methods for generating accurate and reproducible soil analysis results. The CWS PHC tier 1 generic soil-quality guidelines apply to 4 carbon ranges/fractions: F1 (C6-C10), F2 (C10-C16), F3 (C16-...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2578
更新日期:2014-08-01 00:00:00
abstract::The uptake of polar organic contaminants into polar organic chemical integrative samplers (POCIS) varies with environmental factors, such as water flow rate. To evaluate the influence of water flow rate on the uptake of contaminants into POCIS, flow-controlled field experiments were conducted with POCIS deployed in ch...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.305
更新日期:2010-11-01 00:00:00
abstract::Toxic effects of many persistent organic pollutants (e.g., polychlorinated biphenyls or polychlorinated dibenzo-p-dioxins and furans) are mediated via the aryl hydrocarbon receptor (AhR). Although polycyclic aromatic hydrocarbons (PAHs) and their derivatives also activate AhR, their toxic effects remain to be fully el...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-388r.1
更新日期:2006-05-01 00:00:00
abstract::Acute and chronic bioassays were used to evaluate the lethal and sublethal effects of copper chloride and tributyltin chloride on mahi mahi (Coryphaena hippurus) embryos, a pelagic life stage often found in the surface microlayer where anthropogenic contaminants can accumulate. Acute bioassay testing determined the me...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/07-369.1
更新日期:2008-10-01 00:00:00
abstract::Temperature is an important factor affecting toxicity, determining chemical toxicokinetics and toxicodynamics in poikilothermic organisms. Because metabolic rates are also affected by temperature, interactions between the emergence of toxic effects and time are very likely. The aim of the present study was to investig...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2563
更新日期:2014-06-01 00:00:00
abstract::Flexible, rapid, and predictive approaches that do not require the use of large numbers of vertebrate test animals are needed because the chemical universe remains largely untested for potential hazards. Development of robust new approach methodologies and nontesting approaches requires the use of existing information...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4382
更新日期:2019-05-01 00:00:00
abstract::The paucity of information on the occurrence of pharmaceuticals in the environment in African countries led the authors to investigate 8 acidic pharmaceuticals (4 antipyretics, 3 antibiotics, and 1 lipid regulator) in wastewater, surface water, and sediments from the Msunduzi River in the province of KwaZulu-Natal, So...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3144
更新日期:2016-01-01 00:00:00
abstract::Potential differences in species susceptibility to nanoparticle (NP) contaminants make the use of multispecies community toxicity testing strategies beneficial in understanding NP risk to aquatic environments. Because of the limited knowledge of zinc oxide (ZnO) NP fate and toxicity, we conducted multispecies exposure...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4349
更新日期:2019-03-01 00:00:00
abstract::Silver nanoparticles (AgNPs) are efficiently converted during the wastewater-treatment process into sparingly soluble Ag sulfides (Ag2 S). In several countries, sewage sludge is used as a fertilizer in agriculture. The bioavailability of sulfidized Ag to the terrestrial isopod Porcellio scaber was investigated. Sewage...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4102
更新日期:2018-06-01 00:00:00
abstract::Using an ion-exchange-based solid-phase microextraction (SPME) method, the freely dissolved concentrations of C12-benzalkonium were measured in different toxicity assays, including 1) immobilization of Daphnia magna in the presence or absence of dissolved humic acid; 2) mortality of Lumbriculus variegatus in the prese...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2465
更新日期:2014-03-01 00:00:00
abstract::The Baltic Sea is a heavily polluted area. To assess the current contaminant pressure on the common guillemot (Uria aalge) living there, whole-body extracts of guillemots from the Baltic Sea were prepared and subdivided over six fractions, which differed in composition due to lipophilicity and polarity of the contamin...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract::A method is presented for developing scientifically defensible, numeric guidelines for residual petroleum-related constituents, specifically monocyclic aromatic hydrocarbons (MAHs) and polycyclic aromatic hydrocarbons (PAHs), in the water column. The guidelines are equivalent to a HC5 (i.e., hazard concentration to 5%...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/08-271.1
更新日期:2009-06-01 00:00:00
abstract::Loewe's additivity (concentration addition) is a well-known model for predicting the toxic effects of chemical mixtures under the additivity assumption of toxicity. However, from the perspective of chemical risk assessment and/or management, it is important to identify chemicals whose toxicities are additive when pres...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3334
更新日期:2016-07-01 00:00:00
abstract::The Cache Slough complex is an area of tidal sloughs in the Sacramento-San Joaquin River Delta of California (USA), and is surrounding by irrigated agricultural lands. Among the species of concern in the area is the delta smelt (Hypomesus transpacificus), a federally listed threatened species. Releases of the organoph...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2512
更新日期:2014-04-01 00:00:00
abstract::Rate constant bioaccumulation models are applied to simulate the flow of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in the coastal marine food web of Frierfjorden, a contaminated fjord in southern Norway. We apply two different ways to parameterize the rate constants in the model, global sensitivity...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-091r.1
更新日期:2006-01-01 00:00:00
abstract::This study investigates both the methods and the multispecies and functional level effects of a release of a complex hydrocarbon mixture from sediments using a 60-d modified mixed flask culture (MFC) microcosm. Neat Jet-A was injected and mixed into the sediment with one nondosed and three dosed concentrations. Univar...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::A systematic investigation was carried out to analyze the concentration levels of heavy metals in sample seawater, sediments, and biota collected from the coastal area of Yancheng City in Jiangsu Province, China. The authors assessed the impact of these heavy metals in different environmental samples in terms of poten...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2575
更新日期:2014-08-01 00:00:00
abstract::Freshwater mussels, one of the most imperiled groups of animals in the world, are generally underrepresented in toxicity databases used for the development of ambient water quality criteria and other environmental guidance values. Acute 96-h toxicity tests were conducted to evaluate the sensitivity of 5 species of juv...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3642
更新日期:2017-03-01 00:00:00
abstract::Urban stormwater is an important but incompletely characterized contributor to surface-water toxicity. The present study used 5 bioassays of 2 model organisms (Daphnia magna and fathead minnow, Pimephales promelas) to investigate stormwater toxicity and mitigation by full-scale iron-enhanced sand filters (IESFs). Stor...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4227
更新日期:2018-10-01 00:00:00
abstract::Sorption of chemical substances to nanoparticles (NPs) in the aqueous phase strongly influences NP physicochemisty, and investigations of these complex interactions can provide important insights into the environmental fate of NPs. The objective of the present study was to use differences in copper (Cu) bioavailabilit...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4378
更新日期:2019-05-01 00:00:00
abstract::Field populations of aquatic organisms, particularly those inhabiting flowing waters, likely are exposed to short pulses of pesticides following periods of spray drift, surface runoff, or drain flow. In the present study, we investigated the effect of pulse exposures of a pyrethroid insecticide, esfenvalerate, on surv...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-547.1
更新日期:2005-01-01 00:00:00
abstract::Microcystis aeruginosa is a dominant cyanobacterium commonly found in Chinese freshwater ecosystems during phytoplankton blooms, and copper sulfate is one of the most frequently used algicides for controlling the nuisance blooms. In this study, we examined the effects of varied water chemistry (dissolved organic matte...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.266
更新日期:2010-10-01 00:00:00
abstract::Ionic silver is toxic to aquatic organisms at low concentrations. However, complexation to binding sites on natural organic matter has been shown to reduce silver toxicity. Research indicates that there is a need to develop reliable methods for characterizing silver binding at very low silver ion concentrations where ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-577r.1
更新日期:2005-11-01 00:00:00
abstract::Instream flows of the rapidly urbanizing watersheds and estuaries of the Gulf of Mexico in Texas (USA) are increasingly dominated by reclaimed waters. Though ionizable pharmaceuticals have received increasing attention in freshwaters, many research questions remain unanswered, particularly in tidally influenced urban ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3236
更新日期:2016-04-01 00:00:00
abstract::Silver nanoparticles (AgNPs) from industrial use, discharged via the land application of sewage sludge, are interacting with soil biota, including earthworms. In affected organisms, excessive production of reactive oxygen species can result in lipid peroxidation, shifting the balance between oxidants and antioxidants ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4713
更新日期:2020-05-01 00:00:00