Abstract:
:Instream flows of the rapidly urbanizing watersheds and estuaries of the Gulf of Mexico in Texas (USA) are increasingly dominated by reclaimed waters. Though ionizable pharmaceuticals have received increasing attention in freshwaters, many research questions remain unanswered, particularly in tidally influenced urban coastal systems, which experience significant spatiotemporal variability in pH that influences bioavailability and bioaccumulation. The authors coupled fish plasma modeling of therapeutic hazard values with field monitoring of water chemistry variability and pharmaceutical occurrence to examine whether therapeutic hazards to fish existed within these urban coastal ecosystems and whether therapeutic hazards differed within and among coastal locations and seasons. Spatial and temporal fluctuations in pH within study sites altered the probability of encountering pharmaceutical hazards to fish. Significant water quality differences were consistently observed among traditional parameters and pharmaceuticals collected from surface and bottom waters, which are rarely sampled during routine surface water quality assessments. The authors then compared modeling predictions of fish plasma concentrations of pharmaceuticals to measured plasma levels from various field-collected fish species. Diphenhydramine and diltiazem were observed in plasma of multiple species, and diltiazem exceeded human therapeutic doses in largemouth bass, catfish, and mullet inhabiting these urban estuaries. Though the present study only examined a small number of target analytes, which represent a microcosm of the exposome of these fish, coastal systems are anticipated to be more strongly influenced by continued urbanization, altered instream flows, and population growth in the future. Unfortunately, aquatic toxicology information for diltiazem and many other pharmaceuticals is not available for marine and estuarine organisms, but such field observations suggest that potential adverse outcomes should be examined.
journal_name
Environ Toxicol Chemjournal_title
Environmental toxicology and chemistryauthors
Scott WC,Du B,Haddad SP,Breed CS,Saari GN,Kelly M,Broach L,Chambliss CK,Brooks BWdoi
10.1002/etc.3236subject
Has Abstractpub_date
2016-04-01 00:00:00pages
983-95issue
4eissn
0730-7268issn
1552-8618journal_volume
35pub_type
杂志文章abstract::Environment Canada has developed a new 42-d sediment toxicity test method that includes a reproduction test endpoint with the freshwater amphipod Hyalella azteca. Because of concerns that existing standard methodologies, whereby adults are transferred to a water-only exposure before release of their first brood at day...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3453
更新日期:2016-10-01 00:00:00
abstract::Kidney samples of 224 roe deer (113 males, 111 females) aged three months to approximately nine years were collected in eastern Austria. Cadmium contents were examined and histological examinations were performed considering 11 different pathomorphological parameters. Cadmium burden was relatively high (range: 0.010-2...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::Metal pollution has been increasing rapidly over the past century, and at the same time, the human population has continued to rise and produce contaminants that may negatively impact pollinators. Honey bees (Apis mellifera L.) forage over large areas and can collect contaminants from the environment. The primary obje...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3273
更新日期:2016-02-01 00:00:00
abstract::Biofilms can make good bioindicators and biomarkers, offering a convenient tool to monitor metal contamination in streams that results from mine tailing sites. Biofilm metal content (Cu, Zn, Cd, Pb) as well as diatom diversity and the presence of teratologies (diatom abnormalities) were determined for biofilms from ri...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3292
更新日期:2016-06-01 00:00:00
abstract::Radiotracer experiments were conducted to examine the influence of the concentration of Cd, Se, and Zn in ingested phytoplankton (dinoflagellate Prorocentrum minimum and diatom Thalassiosira weissflogii) and in ambient seawater on metal assimilation and elimination efficiencies of three marine copepods, Acartia spinic...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::We conducted a seasonal study of the uptake of Cd, Se(IV), and Zn by natural phytoplankton assemblages collected from two locations in Hong Kong coastal waters. Marine phytoplankton in Port Shelter was dominated by diatoms and cyanobacteria, while phytoplankton in Tolo Harbour was dominated by dinoflagellates. The nat...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-125r.1
更新日期:2005-01-01 00:00:00
abstract::Eutrophication (i.e., nutrient enrichment, organic enrichment, and oxygen depletion) is one of the most common sources of impairment in Clean Water Act 303(d)-listed waters in the United States. Although eutrophication can eventually cause adverse effects to the benthos, it may be difficult to diagnose. Sediment organ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.414
更新日期:2011-03-01 00:00:00
abstract::The toxicity of an acid mine drainage (AMD) mixing zone was investigated by placing bluegill (Lepomis macrochirus) at the confluence of a stream contaminated by AMD and a stream having neutral pH. A mixing channel receiving water from both streams was assembled in the field, during July and October 1996, to determine ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::Methylmercury is the predominant chemical form of mercury reported in the eggs of wild birds, and the embryo is the most sensitive life stage to methylmercury toxicity. Protective guidelines have been based mainly on captive-breeding studies with chickens (Gallus gallus), mallards (Anas platyrhynchos), and ring-necked...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/08-316.1
更新日期:2009-03-01 00:00:00
abstract::Effects of exposure-water pH on chemical uptake at rainbow trout (Oncorhynchus mykiss) gills were investigated for nine weakly acidic, chlorinated phenols with different ionization constants and hydrophobicities and for a moderately hydrophobic, nonionizable reference chemical (1,2,4-trichlorobenzene). Uptake rates fo...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-359r.1
更新日期:2006-06-01 00:00:00
abstract::Environmental pollution with natural or synthetic estrogens may pose a serious threat to reproduction of wildlife species. This study describes the effects of 17-alpha-ethynylestradiol (EE2) on fish reproductive organs in a laboratory model. Adult zebrafish were semistatically exposed to nominal concentrations of 0, 1...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::Tangshan city in Hebei Province is one of the most heavily polluted cities in China, with substantial industrial emissions. The development of effective air pollution emission reduction policies requires knowledge of the sources and health risks of polycyclic aromatic hydrocarbon (PAH)-enriched fine particulate matter...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4618
更新日期:2020-02-01 00:00:00
abstract::Antibiotics are used to maintain healthy livestock and to promote weight gain in concentrated animal feed operations. Antibiotics rarely are metabolized completely by livestock and, thus, are often present in livestock waste and in waste-treatment lagoons. The introduction of antibiotics into anaerobic lagoons commonl...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-093r.1
更新日期:2005-04-01 00:00:00
abstract::Organic compounds in sediments are known to distribute between rapid, slowly, and very slowly desorbing sites. This distribution is relevant to bioavailability and risk assessment of organic compounds in sediment. In this study, the fraction desorbing to Tenax in 6 h was measured for a range of organic compounds in se...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract::Fluorotelomer carboxylic acids (FTCAs) and the corresponding unsaturated acids (FTUCAs) are known intermediates in the biodegradation of industrially produced fluorotelomer alcohols (FTOHs) to environmentally persistent perfluorinated carboxylic acids (PFCAs). The FTCAs and FTUCAs are of concern for their toxicity, re...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.211
更新日期:2010-08-01 00:00:00
abstract::The internalized speciation of lead in roots and leaves of Sesbania drummondii, a lead hyperaccumulator, grown in lead nitrate solution was studied using x-ray absorption near-edge structure and extended x-ray absorption fine structure. Lead was predominantly present as lead acetate in both plant tissues. The other do...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-540
更新日期:2004-09-01 00:00:00
abstract::Adsorption of organic compounds onto hard carbon constituents of soils and sediments may be described by a dual Langmuir-like equation for adsorption onto high-energy sites and low-energy sites. To describe quantitatively the sorbate-sorbent interactions on these high-energy sites and low-energy sites, Gibbs free ener...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/06-218r.1
更新日期:2006-12-01 00:00:00
abstract::On the quantitative comparison of solubilities or vapor pressures of homologous series, the variation in the effect of crystal structure on solid properties may substantially influence the outcome of the comparison. Usually, the effect of this variation is eliminated by comparing values of the liquid state. The ratio ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/06-083r.1
更新日期:2006-11-01 00:00:00
abstract::The effects of antidepressants on wildlife are currently raising some concern because of an increased number of publications indicating biological effects at environmentally relevant concentrations (<100 ng/L). These results have been met with some scepticism because of the higher concentrations required to detect eff...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章,评审
doi:10.1002/etc.3087
更新日期:2016-04-01 00:00:00
abstract::The effects of elevated plasma cortisol levels on vitellogenin (VTG) induction were examined in the fathead minnow (Pimephales promelas) in an attempt to evaluate the potential influence of stress on this commonly used biomarker of estrogenicity. Two separate experiments were conducted in which fish plasma cortisol wa...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-309r.1
更新日期:2005-05-01 00:00:00
abstract::Nitrogen, sulfur, or oxygen heterocyclic aromatic hydrocarbons (NSO-HETs) and short-chained alkyl phenols (SCAPs) are commonly detected in groundwater at contaminated sites and in the surrounding environment. It is now scientific consensus that these chemicals pose a risk to human and ecosystem health. However, toxici...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4423
更新日期:2019-06-01 00:00:00
abstract::Toxicity identification evaluations (TIEs) were performed on seven produced water (PW) effluents from inland discharge facilities operated in Trinidad and Tobago, a Caribbean tropical country with one of the oldest commercial oil industries in the world. The research was performed to determine the presence and magnitu...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/02-530
更新日期:2004-05-01 00:00:00
abstract::Glyphosate is a widely used broad-spectrum postemergent herbicide used for weed control in both agricultural and nonagricultural settings. Spray drift of glyphosate can pose a risk to nontarget terrestrial plants and plant communities outside the intended area of application, but the lack of a well-established predict...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章,meta分析,评审
doi:10.1002/etc.3925
更新日期:2017-11-01 00:00:00
abstract::Polycyclic aromatic hydrocarbons (PAH) and black carbon (BC) were measured in alpine Lake Planina (Slovenia) sediment. Lake Planina is a remote mountain lake with almost no direct anthropogenic influence. Long-distance atmospheric deposition is a major pathway for the loading of contaminants to the sediment. The PAH w...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::Propiconazole is a fungicide used in a variety of agricultural applications. Preliminary studies had suggested that embryos of the crustacean Daphnia magna are particularly susceptible to the toxicity of this chemical. The goals of the present study were to define endpoints of daphnid embryonic development that could ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/1551-5028(2001)020<0502:tfpiwe>2.0.co;2
更新日期:2001-03-01 00:00:00
abstract::Unionid mussels are ecologically important and are globally imperiled. Toxicants contribute to mussel declines, and toxicity tests using juvenile mussels-a sensitive life stage-are valuable in determining thresholds used to set water quality criteria. In vitro culture methods provide an efficient way to propagate juve...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4270
更新日期:2018-12-01 00:00:00
abstract::Octanol-water partition coefficients (KOW ) are widely used in fate and effects modeling of chemicals. Still, high-quality experimental KOW data are scarce, in particular for very hydrophobic chemicals. This hampers reliable assessments of several fate and effect parameters and the development and validation of new mo...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3300
更新日期:2016-06-01 00:00:00
abstract::Neonicotinoid insecticides have been used globally on a wide range of crops through seed treatment as well as soil and foliar applications and have been increasingly studied in relation to the potential risk to bees because of their detection in pollen and nectar of bee-attractive crops. The present article reports th...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4018
更新日期:2018-03-01 00:00:00
abstract::Populations of Cascades frogs (Rana cascadae) have declined precipitously in the Mount Lassen area, but remain abundant in the other half of their California range in the Klamath Mountains. To evaluate the role of contaminants in Cascade frog declines, we sampled sediment and frog tadpole tissue at 31 sites where Casc...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.1902
更新日期:2012-08-01 00:00:00
abstract::The present review describes and discusses key interactions between mercury (Hg) and phytoplankton to highlight the role of phytoplankton in the biogeochemical cycle of Hg and to understand direct or indirect Hg effects on phytoplankton. Phytoplankton are exposed to various Hg species in surface waters. Through Hg upt...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章,评审
doi:10.1002/etc.2424
更新日期:2014-06-01 00:00:00