Abstract:
:Unilateral ligation of a common carotid artery in gerbils causes a decreased rate of serotonin synthesis and degradation but an increased release of this monoamine. In the brain, reduction of cerebral serotonin content during ischemia is followed by accumulation of its main metabolite, 5-hydroxyindolacetic acid. These data support the contention that serotonin plays an important role in the progression of cerebral infarction.
journal_name
Neurologyjournal_title
Neurologyauthors
Mrsulja BB,Mrsulja BJ,Spatz M,Klatzo Idoi
10.1212/wnl.26.8.785subject
Has Abstractpub_date
1976-08-01 00:00:00pages
785-7issue
8eissn
0028-3878issn
1526-632Xjournal_volume
26pub_type
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