Brain serotonin after experimental vascular occlusion.

Abstract:

:Unilateral ligation of a common carotid artery in gerbils causes a decreased rate of serotonin synthesis and degradation but an increased release of this monoamine. In the brain, reduction of cerebral serotonin content during ischemia is followed by accumulation of its main metabolite, 5-hydroxyindolacetic acid. These data support the contention that serotonin plays an important role in the progression of cerebral infarction.

journal_name

Neurology

journal_title

Neurology

authors

Mrsulja BB,Mrsulja BJ,Spatz M,Klatzo I

doi

10.1212/wnl.26.8.785

subject

Has Abstract

pub_date

1976-08-01 00:00:00

pages

785-7

issue

8

eissn

0028-3878

issn

1526-632X

journal_volume

26

pub_type

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