当前位置： SCI文献检索 > AMERICAN HEART JOURNAL期刊下所有文献 > Induction of neointimal hyperplasia by coronary angioplasty balloon overinflation: comparison of feeder pigs to Yucatan minipigs.

Induction of neointimal hyperplasia by coronary angioplasty balloon overinflation: comparison of feeder pigs to Yucatan minipigs.

Abstract：

:We evaluated the use of simple balloon overinflation to induce neointimal hyperplasia in a porcine model of coronary artery restenosis. By using standard percutaneous transluminal coronary angioplasty techniques, left anterior descending (LAD) and/or left circumflex (LCX) coronary arteries of either juvenile feeder pigs or adult Yucatan minipigs were intentionally overinflated. Four weeks later, resultant neointimal hyperplastic responses (neointima/media area; NI/M) were quantitated morphometrically. At all ballooned sites neointimal hyperplasia occurred only when the internal elastic lamina (IEL) was ruptured; the degree of hyperplasia correlated directly with the injury index, that is, the percentage of IEL circumference that fractured (r = 0.74; n = 25; p < 0.05). Despite similar injury indexes in the LAD bed, there was a trend (p = 0.07; analysis of variance) toward greater NI/M ratios in the Yucatan minipig versus the feeder pig group (1.14 +/- 0.21 vs 0.73 +/- 0.09, n = 7/group). We found no such trend in the LCX bed, where the injury index (25.7% +/- 3.5%) was significantly greater than that of the LAD (18.2% +/- 1.2%, p < 0.05). If variations in balloon-induced vascular injury are accounted for, the technique of balloon overinflation of coronary arteries should prove useful in testing potential antirestenotic agents in either adult or juvenile pigs.

journal_name

Am Heart J

journal_title

American heart journal

authors

Humphrey WR,Simmons CA,Toombs CF,Shebuski RJ

doi

10.1016/0002-8703(94)90505-3

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

20-31

issue

1

eissn

0002-8703

issn

1097-6744

pii

0002-8703(94)90505-3

journal_volume

127

pub_type

杂志文章

相关文献

AMERICAN HEART JOURNAL文献大全
  • Prehospital statin use and low-density lipoprotein cholesterol levels at admission in acute coronary syndrome patients with history of myocardial infarction or revascularization: Findings from the Improving Care for Cardiovascular Disease in China (CCC) p

    abstract：BACKGROUND:Lowering low-density lipoprotein cholesterol (LDL-C) by statins is a key strategy for secondary prevention of acute coronary syndrome (ACS). However, few studies have examined prehospital statin use and admission LDL-C levels in ACS patients with history of myocardial infarction (MI) or revascularization. Th...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2019.02.019

    authors： Xing Y,Liu J,Hao Y,Liu J,Huo Y,Smith SC Jr,Ge J,Ma C,Han Y,Fonarow GC,Taubert KA,Morgan L,Yang N,Zhou M,Zhao D,CCC-ACS Investigators.

    更新日期：2019-06-01 00:00:00

  • Outcomes in patients with chronic kidney disease undergoing cardiac rehabilitation.

    abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with an adverse prognosis in patients with coronary heart disease. Cardiac rehabilitation (CR) improves morbidity and mortality among patients with coronary heart disease, but its impact on patients with concomitant CKD has not been described. METHODS:We compared b...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2005.01.048

    authors： Venkataraman R,Sanderson B,Bittner V

    更新日期：2005-12-01 00:00:00

  • High-risk myocardial infarction in the young: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial.

    abstract：BACKGROUND:Advanced age is a well-established prognostic risk factor after acute myocardial infarction (AMI), yet approximately 10% of MIs occur in patients <45 years. We examined characteristics, cardiovascular outcomes, and the influence of risk factors on outcomes in young survivors of AMI. METHODS:Fourteen thousan...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2007.11.016

    authors： Anderson RE,Pfeffer MA,Thune JJ,McMurray JJ,Califf RM,Velazquez E,White HD,Rouleau JL,Skali H,Maggioni A,Solomon SD

    更新日期：2008-04-01 00:00:00

  • Angiographic deterioration of target coronary artery narrowing as a result of percutaneous balloon angioplasty.

    abstract：:We evaluated the long-term angiographic outcome of balloon angioplasty by comparing original and follow-up target coronary narrowing. Rather than using restenosis to determine outcome, as in most angioplasty studies, we took an unusual approach and analyzed outcome in terms that are commonly used in progression and re...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(97)70153-4

    authors： Rozenman Y,Gilon D,Sapoznikov D,Lotan C,Mosseri M,Hasin Y,Gotsman MS

    更新日期：1997-05-01 00:00:00

  • Effects of lidocaine on impulse formation and conduction defects in man.

    abstract：:The acute electrophysiologic effects of a bolus injection of 100 mg. of lidocaine were investigated in 39 patients with impulse formation and conduction defects by means of His-bundle recording and were correlated with plasma lidocaine levels. The effects of therapeutic plasma levels on conduction intervals and refrac...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(75)90183-0

    authors： Roos JC,Dunning AJ

    更新日期：1975-06-01 00:00:00

  • Pulmonary function in hypertensive patients treated with pindolol: a report of two studies.

    abstract：:Pulmonary function was measured serially in two separate randomized trials of pindolol in the treatment of essential hypertension. Patients with overt obstructive airways disease were excluded. In study 1, 131 hypertensive patients were randomized to placebo (31) and 15 mg (33), 30 mg (33), and 60 mg (34) of pindolol....

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-8703(82)90135-1

    authors： Hamilton BP,Hamilton J,Kirkendall WM

    更新日期：1982-08-01 00:00:00

  • The effect of aspirin on the hemodynamic response to nitroglycerin.

    abstract：:The role of prostaglandins in mediating the hemodynamic response to nitroglycerin in vivo is controversial. To determine the effect of inhibiting prostaglandin production on the response to nitroglycerin, either placebo or aspirin (650 mg) was administered 1 hour prior to the administration of nitroglycerin (432 micro...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-8703(88)90252-9

    authors： Levin RI,Feit F

    更新日期：1988-07-01 00:00:00

  • Origin of the basal systolic murmurs in mitral stenosis. A study with intracardiac phonocardiography.

    abstract：:In order to study the origin of the basal systolic murmurs in mitral stenosis, left and right heart catheterization was performed in 18 patients with mitral stenosis using intracardiac phonocardiography. Our data revealed that the basal systolic murmurs originated in the aorta, the pulmonary artery, and the outflow tr...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(78)90163-1

    authors： Kambe T,Suzuki S,Kato T,Hibi N,Fukui Y,Arakawa T,Nishimura K,Miwa A,Sakamoto N

    更新日期：1978-10-01 00:00:00

  • Ischemic ST segment depression in leads V2-V3 as the presenting electrocardiographic feature of posterolateral wall myocardial infarction.

    abstract：:In this study of 14 patients hospitalized with a first event of myocardial infarction, maximal ST segment depression in precordial leads V2 and V3 was the sole ECG finding during chest pain in the first 24 hours of evolving posterolateral infarction, based upon further two-dimensional echocardiographic examination and...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90916-1

    authors： Sclarovsky S,Topaz O,Rechavia E,Strasberg B,Agmon J

    更新日期：1987-05-01 00:00:00

  • Ventricular ectopy in totally symptom-free subjects with defined coronary artery anatomy.

    abstract：:Ambulatory ECG recordings were obtained from 313 consecutive, totally symptom-free male subjects on whom cardiac catheterization was subsequently performed for occupational reasons. These recordings were examined for ventricular ectopy and the results were studied in relation to the findings on selective coronary angi...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(89)90405-5

    authors： Batchelor AJ,Kruyer WB,Hickman JR Jr

    更新日期：1989-06-01 00:00:00

  • Effects of intra-aortic balloon counterpulsation on coronary pressure in patients with stenotic coronary arteries.

    abstract：BACKGROUND:The benefits of intra-aortic balloon pumping (IABP) usage reportedly occur through systolic unloading of the left ventricle and the augmentation of diastolic coronary flow. The aim of this study was to assess the change in intracoronary pressure distal to the coronary stenosis after the IABP by using an intr...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2007.05.019

    authors： Yoshitani H,Akasaka T,Kaji S,Kawamoto T,Kume T,Neishi Y,Koyama Y,Yoshida K

    更新日期：2007-10-01 00:00:00

  • Short-term infarct vessel patency with aspirin and dipyridamole started 24 to 36 hours after intravenous streptokinase.

    abstract：:The duration of intravenous heparin therapy required to maintain patency of the infarct-related artery after intravenous streptokinase is uncertain. Twenty-eight patients were prospectively treated with 1.5 million units of intravenous streptokinase within 4 hours of onset of chest pain. Intravenous heparin was begun ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(88)90870-8

    authors： Hays LJ,Beller GA,Moore CA,Burwell LR,Craddock GB,Gascho JA,Smucker ML,Tedesco C,Nygaard TW

    更新日期：1988-04-01 00:00:00

  • Does aspirin use adversely influence intermediate-term postdischarge outcomes for hospitalized patients who are treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers? Findings from Organized Program to Facilitate Life-Savi

    abstract：BACKGROUND:Conflicting data exist regarding a potential deleterious association between aspirin (ASA) and angiotensin-converting enzyme inhibitors (ACEIs) when used concurrently in patients with heart failure (HF). How such an interaction may be influenced by underlying etiology of HF and whether it extends to patients...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2009.11.009

    authors： Levy PD,Nandyal D,Welch RD,Sun JL,Pieper K,Ghali JK,Fonarow GC,Gheorghiade M,O'Connor CM

    更新日期：2010-02-01 00:00:00

  • Rationale and design of a multicenter randomized trial to compare the graft patency between no-touch vein harvesting technique and conventional approach in coronary artery bypass graft surgery.

    abstract：BACKGROUND:Vein graft failure is a crucial challenge in coronary artery bypass graft (CABG) surgery. Previous studies have suggested a patency benefit of the No-Touch vein harvesting technique, but only with small sample sizes. MATERIALS AND METHODS:This study is a prospective, multicenter randomized clinical trial wi...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2018.11.011

    authors： Wang X,Tian M,Zheng Z,Gao H,Wang Y,Wang L,Hu S

    更新日期：2019-04-01 00:00:00

  • Rationale and Design of Family-Based Approach in a Minority Community Integrating Systems-Biology for Promotion of Health (FAMILIA).

    abstract：BACKGROUND:The 2020 American Heart Association Impact Goal aims to improve cardiovascular health of all Americans by 20% while reducing deaths from cardiovascular disease and stroke by 20%. A large step toward this goal would be to better understand and take advantage of the significant intersection between behavior an...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2017.02.020

    authors： Bansilal S,Vedanthan R,Kovacic JC,Soto AV,Latina J,Björkegren JLM,Jaslow R,Santana M,Sartori S,Giannarelli C,Mani V,Hajjar R,Schadt E,Kasarskis A,Fayad ZA,Fuster V

    更新日期：2017-05-01 00:00:00

  • Borderline left ventricles in prenatally diagnosed atrioventricular septal defect or double outlet right ventricle: echocardiographic predictors of biventricular repair.

    abstract：BACKGROUND:Atrioventricular septal defect (AVSD) and double outlet right ventricle (DORV) with normally related great arteries and normal ventricular sizes are associated with a good long-term prognosis after biventricular (BV) repair. The outcome of cases with a borderline small left ventricle (bLV) is unclear. The pu...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2006.04.018

    authors： Pitkänen OM,Hornberger LK,Miner SE,Mondal T,Smallhorn JF,Jaeggi E,Nield LE

    更新日期：2006-07-01 00:00:00

  • Infective aneurysm of the left ventricle: angiographic and echocardiographic features.

    abstract：:A 17-year-old man with staphylococcal endocarditis of the mitral valve developed an infective aneurysm of the posterior left ventricular wall. Echocardiography revealed an echo-free space posterior to the posterior left ventricular wall. This echo-free space undoubtedly represented the aneurysmal sac, because it could...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(78)90051-0

    authors： Saksena FB,Kramer NE,Towne WD,Khan M,Gamble R,Cruz JB,Gill S

    更新日期：1978-09-01 00:00:00

  • Relationship between changes in ST segment elevation and patency of the infarct-related coronary artery in acute myocardial infarction.

    abstract：:Forty-one patients with acute myocardial infarction and ST segment elevation were studied to determine the relationship between early changes in ST segment elevation, time to peak serum creatine kinase (CK), peak serum CK, left ventricular function, and patency of the infarct-related artery. ST segment elevation decre...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(86)90262-0

    authors： Hackworthy RA,Vogel MB,Harris PJ

    更新日期：1986-08-01 00:00:00

  • Contraceptive methods of privately insured US women with congenital heart defects.

    abstract：BACKGROUND:The American Heart Association recommends women with congenital heart defects (CHD) receive contraceptive counseling early in their reproductive years, but little is known about contraceptive method use among women with CHD. We describe recent female sterilization and reversible prescription contraceptive me...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2020.01.008

    authors： Anderson KN,Tepper NK,Downing K,Ailes EC,Abarbanell G,Farr SL

    更新日期：2020-04-01 00:00:00

  • Clinical and electrophysiologic characteristics of sinoatrial entrance block evaluated by direct sinus node electrography: prevalence, relation to antegrade sinoatrial conduction time, and relevance to sinus node disease.

    abstract：:When AV conduction is normal, the absence of VA conduction is not abnormal. Analogous information about retrograde sinoatrial conduction is not available. Although the premature atrial stimulas (PAS) technique can demonstrate the presence of sinoatrial entrance block (SAEB), both its prevalence and its relationship to...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(81)90484-1

    authors： Reiffel JA,Gang E,Livelli F Jr,Gliklich J,Bigger JT Jr

    更新日期：1981-12-01 00:00:00

  • Residual atrial septal perforation after percutaneous transvenous mitral commissurotomy with Inoue balloon catheter.

    abstract：:To estimate the incidence of residual atrial septal perforation (ASP) following percutaneous transvenous mitral commissurotomy (PTMC) with the Inoue balloon catheter and to examine the factors contributing to ASP, we studied 46 patients with mitral stenosis undergoing PTMC. Residual ASP was evaluated by Doppler color ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(90)90203-a

    authors： Ishikura F,Nagata S,Yasuda S,Yamashita N,Miyatake K

    更新日期：1990-10-01 00:00:00

  • Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study.

    abstract：OBJECTIVES:To define the incidence and cumulative risk of atrial fibrillation (AF) in a population-based cohort of whites and African Americans. BACKGROUND:African-Americans reportedly have a lower risk of AF than whites despite their higher exposure to AF risk factors. However, precise estimates of AF incidence in Af...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2009.05.010

    authors： Alonso A,Agarwal SK,Soliman EZ,Ambrose M,Chamberlain AM,Prineas RJ,Folsom AR

    更新日期：2009-07-01 00:00:00

  • Gender differences in cardiovascular mortality by C-reactive protein level in the United States: evidence from the National Health and Nutrition Examination Survey III.

    abstract：BACKGROUND:The association between C-reactive protein (CRP) and cardiovascular (CV) mortality by gender has not been previously described using a data set that is representative of the US population. METHODS:We used Cox proportional hazards models to explore gender differences in CRP-associated mortality via the Natio...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2013.03.017

    authors： Doran B,Zhu W,Muennig P

    更新日期：2013-07-01 00:00:00

  • Ancrod decreases the frequency of cyclic flow variations and causes thrombolysis following acute coronary thrombosis.

    abstract：:The potential use of ancrod, a purified isolate from the venom of the Malaysian pit viper, Agkistrodon rhodostoma, in decreasing the frequency of cyclic flow variations in severely stenosed canine coronary arteries and causing thrombolysis of an acute coronary thrombus induced by a copper coil was evaluated. Open-ches...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90050-0

    authors： Apprill PG,Ashton J,Guerrero J,Glas-Greenwalt P,Buja LM,Willerson JT

    更新日期：1987-04-01 00:00:00

  • The triglyceride-high-density lipoprotein axis: an important target of therapy?

    abstract：:Coronary heart disease is the single largest cause of morbidity and mortality in the United States. The link between elevated low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) has been clearly established. However, triglycerides (TG) are increasingly believed to be independently assoc...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/j.ahj.2004.03.037

    authors： Szapary PO,Rader DJ

    更新日期：2004-08-01 00:00:00

  • New developments in pharmacologic stress imaging.

    abstract：:The clinical usefulness of cardiac imaging modalities that rely upon the detection of perfusion defects and wall motion disturbances requires conditions that provoke a heterogeneity of coronary flow and a myocardial oxygen imbalance, respectively. Traditionally, this has been achieved by exercise stress testing. Many ...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(92)90614-2

    authors： van Rugge FP,van der Wall EE,Bruschke AV

    更新日期：1992-08-01 00:00:00

  • Cardiac rehabilitation participation predicts lower rehospitalization costs.

    abstract：:The effect of participation in cardiac rehabilitation on medical costs was determined by measuring hospitalization charges for cardiac admissions over a 3-year period in 580 post-coronary event patients (58% after coronary bypass surgery, 42% after myocardial infarction), of whom 230 entered a cardiac rehabilitation p...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(92)90696-s

    authors： Ades PA,Huang D,Weaver SO

    更新日期：1992-04-01 00:00:00

  • Relation between impedance and electrode temperature during radiofrequency catheter ablation of accessory pathways and atrioventricular nodal reentrant tachycardia.

    abstract：OBJECTIVES:Impedance monitoring has been proposed as a method to assess the adequacy of tissue heating during catheter ablation procedures. The purpose of this study was to evaluate the relation among initial impedance, fall in impedance, and electrode temperature during catheter ablation procedures. METHODS AND RESUL...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(98)70130-9

    authors： Nsah E,Berger R,Rosenthal L,Hui R,Ramza B,Jumrussirikul P,Lawrence JH,Tomaselli G,Kass D,Calkins H

    更新日期：1998-11-01 00:00:00

  • Sex-related effectiveness of bivalirudin versus abciximab and heparin in non-ST-segment elevation myocardial infarction.

    abstract：BACKGROUND:Female sex independently predicts bleeding risk after percutaneous coronary intervention (PCI). Bivalirudin is safer than abciximab plus heparin in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Thus, a greater benefit of bivalirudin in women would be expected. METHODS:We performed a...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2012.12.021

    authors： Mehilli J,Neumann FJ,Ndrepepa G,King L,Schulz S,Maimer Rodrigues da Cunha F,Jochheim D,Byrne RA,Hausleiter J,Ott I,Massberg S,Kastrati A,Pache J

    更新日期：2013-04-01 00:00:00

  • Decreased incidence of antiarrhythmic drug efficacy at electrophysiologic study associated with the use of a third extrastimulus.

    abstract：:Drug trials during electrophysiologic study were performed in 166 patients with sustained ventricular tachycardia (VT) or ventricular fibrillation. In the first 21 patients (group I), a maximum of two extrastimuli was used. In 145 subsequent patients (group II), drug efficacy was assessed using three extrastimuli if o...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(82)90432-x

    authors： Swerdlow CD,Blum J,Winkle RA,Griffin JC,Ross DL,Mason JW

    更新日期：1982-11-01 00:00:00