Abstract：
:The plaque-neutralization method developed by Dulbecco and co-workers for the study of the virus of western equine encephalomyelitis in cultures of chick fibroblasts, though probably unequalled for accuracy, has not been adopted for general use in laboratories engaged in research on the arthropod-borne viruses, for two reasons: (a) the belief that the technique would be suitable only for viruses with a powerful cytopathic effect on chick-embryo cells, and (b) the laborious procedures involved.The simple plaque-inhibition test described in this paper was devised with the requirements of the field or diagnostic laboratory in mind; while less precise than Dulbecco's method, this test is sufficiently accurate for many purposes and is far less laborious. The range of applicability of the technique is discussed, the author claiming that it can be used both as a qualitative test for the presence of neutralizing antibodies to a particular plaque-producing virus and as a test for the identification of unknown plaque-producing viruses.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
PORTERFIELD JSsubject
Has Abstractpub_date
1960-01-01 00:00:00pages
373-80eissn
0042-9686issn
1564-0604journal_volume
22pub_type
杂志文章abstract：:Much has been learnt of the epidemiology of yaws during eradication campaigns in populations in which the prevalence of active yaws was high, but not all has been published. The recognition of the importance of latent cases in the maintenance of yaws has contributed to the effectiveness of these campaigns. Yaws eradic...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1960-01-01 00:00:00
abstract：:Analysis of three years of data from a malaria clinic operated by the Indian Council of Medical Research (ICMR) in the Government Medical College Hospital in Jabalpur, central India, showed a high malaria prevalence among pregnant women, which was statistically highly significant (P < 0.0001) compared with the situati...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Urban living is the keystone of modern human ecology. Cities have multiplied and expanded rapidly worldwide over the past two centuries. Cities are sources of creativity and technology, and they are the engines for economic growth. However, they are also sources of poverty, inequality, and health hazards from the envi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:Tuberculin is known to be adsorbed to containers and syringes. In the present paper, the adsorption which takes place in the ampoules has been studied in relation to the diluent for the tuberculin.Adsorption was most evident in dilutions prepared with saline or with phosphate buffer containing dextran. The inclusion i...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1958-01-01 00:00:00
abstract：:Poxviruses were isolated from the kidneys of an outwardly healthy chimpanzee trapped in an area of the Democratic Republic of the Congo where a case of monkeypox had recently occurred in man, from the kidneys of clinically healthy cynomolgus monkeys in a colony in the Netherlands, and from monkeys suffering from monke...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:In many health facilities in east Africa, haemoglobin estimation is performed using visual colour comparison methods. Efforts to establish colorimetric methods face numerous constraints, including the unavailability of standards for quality control. In contrast, the alkaline haematin D-575 method for haemoglobin estim...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Genomics, the comprehensive examination of an organism's entire set of genes and their interactions, will have a major impact on the way disease is diagnosed, prevented and treated in the new millennium. Despite the tremendous potential it holds for improving global health, genomics challenges policy-makers to ensure ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:Quantitative data are presented on the viability of El Tor vibrios in various foodstuffs under different conditions. El Tor vibrios were found to have a very short life in water at -20 degrees C, but in various nutrient media, such as skim milk, sugar solution or meat extract, they could live for more than a month at ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1967-01-01 00:00:00
abstract：:Studies were conducted each month for one year to determine the cercarial-incubation periods of Schistosoma haematobium and Schistosoma bovis in Bulinus truncatus for different months of infection. The snails were kept in outdoor aquaria in order to simulate the natural temperature conditions in the endemic bilharzias...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:Immunization of non-pregnant women in rural Bangladesh with two doses of aluminium-adsorbed tetanus-diphtheria toxoids reduced neonatal mortality by one-third during a period of 9-32 months after vaccination. The reduction in mortality rate was attributable almost entirely to a 75% lower mortality rate among 4-14-day-...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Described are the results of an international collaborative study to evaluate the use of whole blood samples spotted on filter-paper (BSP) for the detection of antibodies to human immunodeficiency virus type 1 (HIV-1). BSP samples were collected from 40 patients at risk for HIV-1 infection and tested blindly using com...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:LATEX/IgM, a rapid agglutination test for the semi-quantitative detection of IgM in cerebrospinal fluid of patients with African trypanosomiasis, is described in this article. The lyophilized reagent has been designed for field use and remains stable at 45 degrees C for one year. The test has been evaluated on cerebro...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Hospital- and community-based studies were conducted in central Sudan to investigate the association between pesticide exposure and perinatal mortality. The cases were 197 stillbirths in the hospital and 36 perinatal deaths in the community; the controls were 812 liveborn, normal-birth-weight infants in the hospital, ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The use of BCG vaccine in the prevention of leprosy has been one of the most important subjects of investigation in the field of leprology in the last 25 years. The action of the vaccine was for many years investigated by determining its effect on the lepromin reaction. Field studies were later considered essential to...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：OBJECTIVE:To explore what individuals at risk of injury from using paraffin (also known as kerosene) know about paraffin safety, what they do to protect themselves and their families from paraffin-related injury, and how they perceive their risk for such injury. Also, to explore interrelations between these factors and...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.08.057505
更新日期：2009-09-01 00:00:00
abstract：:New initiatives are aiming to reduce the global burden of schistosomiasis, mainly through the large-scale application of chemotherapy. To target chemotherapy effectively, rapid assessment procedures are needed for identifying high-risk communities that are foci for the disease. In this review, we examine the developme...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：Objective:To estimate the level and trend of development assistance for community health worker-related projects in low- and middle-income countries between 2007 and 2017. Methods:We extracted data from the Organisation for Economic Co-operation and Development's creditor reporting system on aid funding for projects t...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.19.235499
更新日期：2020-01-01 00:00:00
abstract：:This paper is an attempt to relate modifications observed in general and infant mortality rates with the dynamic changes in transmission induced by malaria control measures. The observations indicated relationships between the efficacy of control and a decrease in mortality. The daily parasitological inoculation rate ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Since an excellent candidate strain (M) for live virus vaccination of swine against Japanese encephalitis was developed, a number of large vaccination programmes have been implemented in Japan with the aim of controlling Japanese encephalitis epidemics in man by reducing the population size of nonimmune swine. Encoura...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：OBJECTIVE:To document the inclusion of key medicines for children in national essential medicines lists (EMLs) and standard treatment guidelines, and to assess the availability and cost of these medicines in 14 countries in central Africa. METHODS:Surveys were conducted in 12 public and private sector medicine outlets...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.08.053645
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:We sought to assess the current status of global data on death registration and to examine several indicators of data completeness and quality. METHODS:We summarized the availability of death registration data by year and country. Indicators of data quality were assessed for each country and included the tim...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：/S0042-96862005000300009
更新日期：2005-03-01 00:00:00
abstract：:The biological effects of tuberculin in an organism infected with tubercle bacilli are due to an unknown number of different substances, which are present in varying concentrations in different tuberculin preparations. Consequently, the response to tuberculin tests with various products is likely to vary with the biol...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1964-01-01 00:00:00
abstract：:Sera were collected from 320 shearwaters (Puffinus pacificus chlororhynchus) nesting on two islands off the east coast of northern Australia in December 1969. About 10% of these sera specifically inhibited the neuraminidase of the 1957 strain of human influenza (A2/Asian/57), some to high titre.The neuraminidase of A2...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：:DEC (diethylcarbamazine)-medicated salt, at a concentration of 0.1 to 0.2 mg per 100 mg, was given to the entire population of Karaikal (119 978) in South India for a 4-year period from 1982. The per capita consumption of DEC in medicated salt was 13.3 grams for the entire period. The prevalence of microfilaraemia dec...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The ParaSight(R)-F test is a qualitative diagnostic test of Plasmodium falciparum, which is based on the detection by a monoclonal antibody of a species-specific soluble antigen (histidine-rich protein (HRP-II)) in whole blood and which can be performed without special equipment. A visual reading is given by a polyclo...
journal_title：Bulletin of the World Health Organization
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-01-01 00:00:00
abstract：:Administration of live influenza vaccine produces an asymptomatic immunizing infection of the respiratory tract with the appearance of antibodies in the secretions of the respiratory passages.Because of natural variation in the antigenic and biological properties of the influenza virus, new vaccines must be developed ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1969-01-01 00:00:00
abstract：OBJECTIVE:To develop, in a mortuary setting, a pilot programme for improving the accuracy of records of deaths caused by injury. METHODS:The recording of injury-related deaths was upgraded at the mortuary of the Komfo Anokye Teaching Hospital, Kumasi, Ghana, in 1996 through the creation of a prospectively gathered dat...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:An epidemic of sleeping sickness, which started in 1976 in a focus within the county of Luuka in Central Busoga, has spread to cover the three districts of Busoga and large parts of the neighbouring districts of Tororo and Mukono. Forty-three isolates of the subgenus Trypanozoon from Busoga and Tororo (27 from man, 9 ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of the disease, but cases continued to occur. Introduction of oral poliovirus vaccine (OPV) in mid-1961 had a dramatic effe...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:To characterize the epidemiology of dysentery (defined as bloody diarrhoea) in Burundi, we reviewed national surveillance data and conducted a household cluster survey including two case--control studies: one at the household, the other at the individual level. We estimated that community incidences for dysentery (per...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
