Abstract:
INTRODUCTION:An epidemiological study of inflammatory bowel disease (IBD) in Veszprém county (located in western part of Hungary) was carried out from 1977 to 2001. METHODS:Both hospital and outpatient records of IBD patients were collected reviewed carefully. Most patients have been followed up regularly. RESULTS:The number of population has decreased during the observed period from 386,000 to 376,000. The county has both industrial and agrarian parts. 560 new ulcerative colitis (UC) cases, 212 Crohn's disease (CD), and 40 indeterminate colitides (IC) were diagnosed in the investigated period. Incidence rate increased from 1.66 (1977-1981) to 11.01 (1997-2001) in UC, and from 0.41 to 4.68 in CD, respectively. The incidence rate in IC rose from 0.26 to 0.74. The M/F ratio in UC was 1.06, in CD: 1.03, respectively, 41 UD patients and 13 CD patients died, the cause of death was disease related in 6 UC and in 6 CD patients. The average age at death in UC was not different from that observed in general population (66.4 years) but in CD (50.1 years) it was much earlier. The disease related mortality was low, 0.06/100,000 both in UC and CD. The prevalence rate at the end of 2001 was 142.6 for UC and 52.9/100,000 inhabitants for CD. Mean age at onset in UC was 38.9 +/- 15.5 years, in CD 31.7 +/- 12.8 years. We observed only one peak onset of the diseases, in UC it was between 30 and 40 years, in CD between 20 and 30 years. People living in towns were more liable to acquire the disease (ORUC = 1.27, ORCD = 1.13). The rate of smokers at the onset was 14.3% (OR = 0.25) in UC and 50.5% (OR = 1.98) in CD. Ex-smokers were 18.4% and 6.4%. Family history of IBD was present in 3.4% in UC and 9.9% in CD. The location of UC (according to the known largest extent) was proctitis in 112 cases, proctosigmoiditis in 162 cases, left sided colitis in 117 and subtotal or pancolitis in 169 cases. The location of CD was only ileal in 68 cases, ileocolonic in 87 cases, colonic in 57 cases. The behaviour of CD was non-stricturing-non-penetrating in 63 cases, stricturing in 54 cases, penetrating in 95 cases. 59.4% of the CD patients had at least one operation, 6.1% had more than 3 operations. CONCLUSION:The incidence and prevalence rates have increased steadily in Veszprém County, now it reaches that of most western European countries. There were no gender differences either in UC or CD. Smoking seemed to be a risk factor for CD, but it was preventive for UC. The rapid increase in incidence supports a role for environmental (e.g. diet, lifestyle changes) risk factors.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Lakatos L,Mester G,Erdélyi Z,Balogh M,Szipócs I,Kamarás G,Lakatos PLsubject
Has Abstractpub_date
2003-09-14 00:00:00pages
1819-27issue
37eissn
0030-6002issn
1788-6120journal_volume
144pub_type
杂志文章相关文献
ORVOSI HETILAP文献大全abstract::The autonomic nervous system has a crucial role in the genesis, maintenance and abruption of atrial fibrillation. The substrate and trigger mechanism of atrial fibrillation can be influenced by the changing autonomic tone. The authors summarize the current knowledge on the relationship between autonomic nervous system...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2008.28466
更新日期:2008-10-26 00:00:00
abstract::Authors analysed 25 colorectal cancer lung metastases. Among them were 13 male 12 female. Ages ranged from 45 to 70 years. The lung nodules were discovered without any symptoms in 19 cases. The disease was localized on the right in 16 patients, in 7 on the left side and 2 others were bilateral. There were 19 solitary ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-01-29 00:00:00
abstract::Transient elevation of the ST segment was observed in a patient during noncardiogenic shock. The coronarography was negative. The patient received dopamine infusion. The 48 yr-old man had Crohn disease with septicaemia and ARDS. The exact pathomechanism is not known, but the negative coronarography ruled out the epica...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2005-05-08 00:00:00
abstract::The authors present the case history of a 2 year old child suffering from nesidioblastosis. Severe non-ketotic symptomatic hypoglycaemia developed within the first hour of birth. Diagnosis of nesidioblastosis was confirmed by high insulin concentration accompanying hypoglycaemia, the increase in blood glucose level af...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-07-23 00:00:00
abstract::An echocardiographic follow-up of 25 patients (pts) was performed, after the first examinations in 1978-1979. 15 pts have died in the last 15 years (Group 1), while 10 still living (Group 2). In Group 1 either the impaired global left ventricular at the time of the first echocardiography predicted a high mortality i.e...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1995-07-16 00:00:00
abstract::The DNA (chip) technology, emerged in the last two years, provides an incredible technical development in rapid and automatised performance of genetic identification. The principle of procedure is, that by series of photolitographic and chemical steps on solid-phase of a small surface relatively dense oligonucleotide ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1998-04-19 00:00:00
abstract::The concentration of HbA1c, glycosilated serum proteins and blood glucose were followed up during the first eight postnatal weeks in 10 preterm babies of mean (+/- SD) birthweight and gestational age of 1259 +/- 140 g and 30.2 +/- 2.0 weeks, respectively. Both blood glucose and the glucosilation of proteins remained u...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1992-05-24 00:00:00
abstract::Due to modern living conditions the human cardiovascular system is frequently exposed to rapid or/and prolonged changes in gravitational forces. These transients are very short compared to the timescale of the evolution causing substantial difficulties in adaptation. As it has been many times proven experimentally sin...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-02 00:00:00
abstract::Polycystic ovary syndrome is recognized as the most common hormonal and metabolic disorder of women. This heterogeneous endocrinopathy characterized by clinical and/or biochemical hyperandrogenism, oligo- or amenorrhoea, anovulatory infertility, and polycystic ovarian morphology. The prevalence, clinical feature and t...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2014.29941
更新日期:2014-07-27 00:00:00
abstract::A rare form of pause dependent form of torsade de pointes ventricular tachycardia and T-wave alternans is reported. The life-threatening ventricular arrhythmia was associated with left sided intracerebral hemorrhage and elevated CKMB mass and Troponin T (0.14 ng/ml). The possible pathomechanism of torsade de pointes t...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2003-10-19 00:00:00
abstract::The authors observed ischaemic damages in jejunal loops used for esophageal reconstruction with full or partial regeneration. In addition to the case reports, they discuss the cause, the mechanism, the possible prevention and correction of this rare complication. ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1997-11-23 00:00:00
abstract::Összefoglaló. A malignus csonttumorok sebészi ellátása során kialakuló szegmentális csontdefektusok pótlása fontos szempont a végtagmegtartó sebészetben. Felnőttkorban a megoldás rendszerint tumorprotézis beültetése, 10 évesnél fiatalabb gyermekeknél azonban ez nehezen alkalmazható módszer a kis csontméret és az igen ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31767
更新日期:2020-11-08 00:00:00
abstract:AIM:The authors sought to investigate the occurrence of complications and adverse events among patients participating in phase II. Residential cardiac rehabilitation program after coronary event (myocardial infarction, transluminal coronary angioplasty or coronary artery bypass graft operation) and determine the factor...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2006-04-16 00:00:00
abstract:INTRODUCTION:Collected and archived serum samples could be important sources for genetic studies, once DNA suitable for molecular genetic studies could be obtained from them. METHODS:DNA was isolated from 54 archived sera samples, collected previously from the participants of a Hungarian allergy study, with commercial...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2004-11-21 00:00:00
abstract::Cerebral ischemia, caused by disturbance of the blood supply to the brain, is a major cause of death in our days. Diabetes mellitus exacerbates neuronal death induced by an ischemic insult. It is important to characterize the underlying mechanism of the cell damage in order to design therapeutic agents. The purpose of...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2006-10-01 00:00:00
abstract:AIMS:The objective of this study was to measure the health-related quality of life of the Hungarian general population. The quality of life survey was part of the National Health Survey (Országos Lakossági Egészségfelmérés, OLEF) conducted in year 2000 on a representative sample of 5503 members of the general populatio...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2003-08-24 00:00:00
abstract::Introduction: Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular disorder. The most important symptom is vertigo, which is triggered by changes in head position and sometimes is accompanied by vegetative symptoms. Furthermore, etiology may be subcategorized into idiopathic and seconda...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31646
更新日期:2020-02-01 00:00:00
abstract::Otosclerosis is a human-specific ear disease characterised by complex bone-remodelling with multifactorial aetiology. It affects the bony labyrinth capsule and consequently fixates the stapes to the oval window rim. The fixation of the ossicular chain leads to a decrease in the middle ear's acoustic impedance-fitting ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2020.31701
更新日期:2020-05-01 00:00:00
abstract::Authors review nation-wide hospital data of amputees over two years in order to make comparison with similar data gathered about 20 years ago. Data were provided by the National Medical Records Centre and processed by own developed programmes. The quality level of data validity is slightly criticised. The cause of amp...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1997-09-14 00:00:00
abstract::The authors present the computer dynamic pedobarographic analyse method of the diabetic foot with case reports. The diabetic foot is described in the literature by interdisciplinar teams, and the authors recommend this method in the identification of the high pressure areas of the foot. By this way the orthotic specia...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-07-02 00:00:00
abstract::Compression of the rostral ventrolateral medulla oblongata is one of the rarely identified causes of refractory hypertension. In patients with severe, intractable hypertension caused by neurovascular compression, neurosurgical decompression should be considered. The authors present the history of a 20-year-old man wit...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2014.29908
更新日期:2014-05-25 00:00:00
abstract::Introduction: Uveitis is characterized by inflammation of the middle layer of the eye. Its overall incidence is low. Autoimmune diseases and infections are the most common underlying diseases. Out of the autoimmune diseases, juvenile idiopathic arthritis is associated most frequently with uveitis. The topical ophthalm...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2019.31459
更新日期:2019-08-01 00:00:00
abstract::Clinical and morphological characteristics of two malignant cystosarcoma phyllodes mammae were reported with the review of recent literature. One of the patients went to see her doctor 2 years after she had noticed the tumour because of "problems in her family". In the removed giant fibroadenoma osteo-chondrosarcomato...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1994-10-09 00:00:00
abstract::Billions of microorganisms can be found in the oral cavity, from which bacteria are the most frequent. More than 600 bacterial species can be isolated. Most of them are harmless, moreover, some species prove themselves to be specifically useful. However, in the case of a weakened immune status or inappropriate oral hy...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2019.31377
更新日期:2019-05-01 00:00:00
abstract::Antibodies against ENA (Extractable Nuclear Antigens), SSA/Ro and SSB/La were investigated in parallel in the serum and the immune complex precipitates of 41 patients with autoimmune disease (10 systemic lupus erythematosus, 23 discoid lupus erythematosus, 3 subacute cutaneous lupus erythematosus, and 5 progressive sy...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1992-05-03 00:00:00
abstract::The authors give account of their study concerning the effect of paracetamol on the acid haemolysis, and glutathione content of human erythrocytes. In vitro, paracetamol decreased intracellular glutathione content in a dose dependent manner. This may lead to an increased sensitivity of erythrocytes to the haemolytic e...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1993-10-10 00:00:00
abstract::Transcatheter arterial oily chemoembolization using cytostatics mixed with lymphographic contrast agent with or without Gelfoam embolization seems currently to be the most suitable treatment for unresectable hepatocellular carcinomas (HCC). 5 patients with inoperable, biopsy proven huge HCC (average size 404 cm2) were...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1994-01-30 00:00:00
abstract::270 psoriatic arthritis patients were studied retrospectively. 65 patients of them were treated with aurothiomalate. The drug was effective in 62% of aurothiomalate treated patients, in 35% were registrated side effects. These data correspond to the experiences with gold salt treatment in rheumatoid arthritis. Exacerb...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1990-01-28 00:00:00
abstract::It is known that time-zone fatigue (jet lag syndrome) a transient physiological and mental condition occurs when people travel by jet between zones with time differences of five hours or longer. Jet lag syndrome is considered to develop because of internal desynchronization that results from a sudden difference betwee...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1994-08-07 00:00:00
abstract::Two cases of intramural hematoma arising in the duodenum and the stomach are reported. Both patients were male, aged 40 and 58 years, and suffered from chronic pancreatitis. Hematoma of the duodenal wall may have resulted from the acute exacerbation of the chronic pancreatitis in the first patient. As to the second ca...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-06 00:00:00