Abstract:
:IF-liposomes are formed by a unique process that involves fusing small liposomes into interdigitated lipid sheets, using either ethanol or hydrostatic pressure. The interdigitation-fusion method requires liposome formulations with lipids that form the L beta I phase. Preparing ethanol-induced IF-liposomes is simple and quick. IF-liposomes are particularly well suited for biomembrane research experiments that require large unilamellar liposomes and for liposome drug delivery applications that require a high drug-to-lipid ratio.
journal_name
Methods Enzymoljournal_title
Methods in enzymologyauthors
Ahl PL,Perkins WRdoi
10.1016/S0076-6879(03)67007-2subject
Has Abstractpub_date
2003-01-01 00:00:00pages
80-98eissn
0076-6879issn
1557-7988pii
S0076687903670072journal_volume
367pub_type
杂志文章abstract::Cell migration plays a key role both in physiological conditions, such as tissue repair or embryonic development, and in pathological processes, including tumor metastasis. Understanding the mechanisms that allow cancer cells to invade tissues during metastasis requires studying their ability to migrate. While spectac...
journal_title:Methods in enzymology
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abstract::Flavoenzymes comprise a large class of proteins that carry out a diverse range of important redox chemistry. Although X-ray crystal structures of many flavoenzymes have been determined, there are still unresolved questions regarding the actual oxidation state of the flavin cofactors in these structures due to photored...
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