Abstract：
:Twenty-seven patients with carcinoma of the bladder were treated at the Glasgow Institute of Radiotherapeutics as part of a national hyperbaric oxygen trial. These patients were treated on a 4 MeV linear accelerator either in air or in 3 atm, absolute, of oxygen, by random selection. Of these patients, one-third were found to have high-dose effects to an extent which necessitated surgery. No association was found between the incidence of high-dose effects and treatment in air or hyperbaric oxygen. The treatment protocol used in all cases was to give an intended modal tumour dose of 6000 rad in 24 fractions in approximately 5 weeks. As all patients had received the same modal dose, there was no apparent reason why some had developed high-dose effects. However, on the basis of a Cumulative Radiation Effect (CRE) analysis of the treatment regimes given, a close correlation was found between the maximum CRE achieved and the occurrence of high-dose effects. Above a threshold level of 1910 reu in the maximum CRE achieved, there was a high incidence and rapid onset of high-dose effects. The reasons for the occurrence of the exceptionally high CRE values found in some patients are discussed. From a review of clinical results of bladder treatments, it is apparent that at a CRE level of 1910 reu, the tumour control rate is still increasing with CRE. It is proposed that by choosing the dose given on any treatment schedule to keep the maximum value of the CRE achieved just below 1910 reu, the greatest probability of cure would be obtained with minimum complication rate.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Kirk J,Wingate GW,Watson ERdoi
10.1016/s0009-9260(76)80134-1subject
Has Abstractpub_date
1976-04-01 00:00:00pages
137-44issue
2eissn
0009-9260issn
1365-229Xpii
S0009-9260(76)80134-1journal_volume
27pub_type
临床试验,杂志文章,随机对照试验abstract：AIM:To evaluate the utility of the elastic ratio calculated using real-time tissue elastography for assessing liver fibrosis in patients with chronic hepatitis B (CHB). MATERIALS AND METHODS:Ninety-six patients with CHB were enrolled between September 2012 and August 2013. The elastic ratio of the liver for the intrah...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2013.10.003
更新日期：2014-02-01 00:00:00
abstract：:The aim of this study was to determine the incidence and cause of axillary lymphadenopathy detected by screening mammography and to devise a management protocol for this pathology. In a retrospective study of 95,806 consecutive screening mammograms, 37 cases of 'pathological' axillary nodes were identified using two o...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(97)80008-6
更新日期：1997-06-01 00:00:00
abstract：:The results of 100 attempts at endoscopic retrograde cholangio-pancreatography (ERCP) performed in patients with jaundice have been reviewed. The examination provided a diagnosis in 75% of cases. The reason for failure to cannulate the correct duct was obstruction at the lower end of the common bile duct in 15 patient...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(78)80236-0
更新日期：1978-03-01 00:00:00
abstract：:Non-invasive CT coronary artery imaging has previously had little relevance to most UK radiologists due to the limited availability of electron beam CT scanners. Major advances in CT technology have promoted new applications for helical CT, which include cardiac imaging. Widespread installation of 'multislice' helical...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1053/crad.2002.1072
更新日期：2002-10-01 00:00:00
abstract：AIM:To identify the most effective manual aspiration thrombectomy (MAT) method for the initial endovascular management of acute deep-vein thrombosis (DVT) in the lower extremity using a phantom model. MATERIALS AND METHODS:An acute DVT phantom model was created by infusing a bovine acute thrombus in a 20-mm diameter, ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2015.11.016
更新日期：2016-04-01 00:00:00
abstract：:Castleman disease is a rare, benign disorder characterized by proliferation of lymphoid tissue most commonly presenting as a solitary mediastinal mass. We discuss the radiological findings in a 10-year-old female child with a mesenteric Castleman tumour presenting with intermittent abdominal pain and a persistently el...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)80578-1
更新日期：1991-06-01 00:00:00
abstract：AIM:To evaluate whether radiologists can accurately differentiate Wilms' tumours from other paediatric abdominal masses with renal involvement using modern imaging methods alone. METHODS:From February 1993 to June 1997, 23 patients presented to the Paediatric Oncology Service at The Royal Hospital for Sick Children, E...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(99)90563-9
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To determine the effect of breathing on the detection of small dense pulmonary nodules of threshold conspicuity by spiral computed tomography (SCT). MATERIALS AND METHODS:Forty pulmonary nodules of high density were created by endobronchial deployment of 2 and 4mm diameter beads in the peripheral airways of ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(98)80170-0
更新日期：1998-07-01 00:00:00
abstract：AIM:To review the literature on the use of prophylactic balloon occlusion alone and in conjunction with arterial embolization of the internal iliac arteries in women with placenta accreta. MATERIALS AND METHODS:The PubMed, MEDLINE, CINAHL, EMBASE, and Cochrane Library databases were searched for keywords related to th...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2011.10.031
更新日期：2012-06-01 00:00:00
abstract：AIM:To investigate the frequency, clinical significance, and outcome of small-bowel intussusceptions in adults detected using ultrasound in an outpatient setting. PATIENTS AND METHODS:In two different retrospective (January 2001 to April 2003) and prospective (May 2003 to June 2005) periods, 33 small-bowel intussuscep...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2007.02.009
更新日期：2007-08-01 00:00:00
abstract：:The clinical, radiological and histological findings are described in nine cases of infiltrating epitheliosis. In seven cases the mammogram revealed 2.5-5.0 cm discoid radial scars which conformed with the histological features and there was no associated significant clinical abnormality. It can be difficult to differ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(83)80235-9
更新日期：1983-07-01 00:00:00
abstract：:The anterior cruciate ligaments of 20 patients with suspected pathology in one ligament were studied by thin-section computed tomography (CT) and reformating techniques. In 19 patients, the suspect anterior cruciate ligament was abnormal and this was confirmed by subsequent arthroscopy or arthrotomy in thirteen. Thin-...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(84)80111-7
更新日期：1984-07-01 00:00:00
abstract：AIM:To investigate the utility of diffusion-weighted (DW) magnetic resonance imaging (MRI) in the diagnosis of abdominal wall endometrioma (AWE) and to compare the ADC (apparent diffusion coefficient) values of AWE with those of the uterine endometrium during two different phases of the menstrual cycle. MATERIALS AND ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2013.08.015
更新日期：2014-02-01 00:00:00
abstract：AIM:To examine the functional brain alterations in Parkinson's disease (PD) by measuring blood oxygenation level dependent (BOLD) functional MRI (fMRI) signals at rest while controlling for the structural atrophy. MATERIALS AND METHODS:Twenty-three PD patients and 20 age, gender, and education level matched normal con...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2015.10.006
更新日期：2016-01-01 00:00:00
abstract：AIM:To compare the diagnostic utility of pelvic ultrasound (US) and magnetic resonance imaging (MRI) on the clinical decision to proceed with uterine artery embolization (UAE). MATERIALS AND METHODS:Over 2 years, 180 consecutive women (mean age 43) sought consultation for UAE, 116 underwent pelvic US and MRI before po...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2010.08.005
更新日期：2011-01-01 00:00:00
abstract：:In a review of 127 urethrocystograms carried out on 92 males with spinal cord injury the following conclusions were drawn. (1) In the presence of vesico-ureteric reflux or urethral reflux into the male adnexa, bladder outlet obstruction should be suspected. (2) Lesions of the anterior urethra develop easily as the res...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(84)80066-5
更新日期：1984-11-01 00:00:00
abstract：:Twenty-nine United Kingdom deep sea divers were examined radiographically for skeletal abnormalities and also bone images were obtained using technetium-99m methylene diphosphonate. The results of the two forms of examination were compared and the use of radionuclide bone scanning was shown to be more sensitive than r...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(87)80332-x
更新日期：1987-11-01 00:00:00
abstract：AIM:To demonstrate the magnetic resonance imaging (MRI) appearances of intact and ruptured Trilucent TM implants with imaging and surgical correlation. The appearances of the implant transponder artefact are also described MATERIALS AND METHODS:A retrospective review of the MRI findings in 34 patients with bilateral s...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1053/crad.2001.0767
更新日期：2002-04-01 00:00:00
abstract：AIMS:To test the hypothesis that the improved resolution afforded by 16-detector computed tomography (CT) would translate to better stress fracture detection when compared with skeletal scintigraphy. MATERIALS AND METHODS:Thirty-three cases of suspected stress fractures in 26 patients were investigated using skeletal ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2005.05.014
更新日期：2005-10-01 00:00:00
abstract：:The commonest causes of nasal obstruction are rhinitis and chronic rhinosinusitis, which affect up to 30% and 14% of the adult population, respectively. The global financial burden is huge, estimated at $5 billion for rhinitis and $8.6 billion for chronic rhinosinusitis per annum in the USA. On referral for imaging, c...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2019.07.027
更新日期：2020-09-01 00:00:00
abstract：:A retrospective analysis of the effect of oral and intravenous hyoscine N butylbromide (Buscopan) on the dimensions of the large bowel during double contrast barium enema (DCBE) examination was made and compared with corresponding measurements without Buscopan. It was found that 20 mg oral Buscopan did not alter colon...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(82)80258-4
更新日期：1982-05-03 00:00:00
abstract：:The pre-operative images of three patients with biopsy proven esthesioneuroblastoma are presented. The role of computed tomography (CT) and magnetic resonance imaging (MRI) in the pre-operative determination of tumour extent is discussed. ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)83295-7
更新日期：1995-09-01 00:00:00
abstract：AIM:Peripherally inserted central catheters (PICC) are increasingly used as a route of chemotherapy administration. Our aims were to assess a collaborative approach to PICC placement, with radiological support for a nurse led line insertion service in a minority of cases, and to determine whether PICC provided a safe a...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1053/crad.2001.0843
更新日期：2002-05-01 00:00:00
abstract：:The creation of an intrahepatic portosystemic shunt via a transjugular approach (TIPS) is an interventional radiological procedure used to treat the complications of portal hypertension. TIPS insertion is principally indicated to prevent or arrest variceal bleeding when medical or endoscopic treatments fail, and in th...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2008.09.017
更新日期：2009-07-01 00:00:00
abstract：:The ultrasound features in eight cases of metastases to the thyroid are reported. The primary tumours were bronchogenic carcinoma (4 cases), breast carcinoma (2 cases), oesophageal carcinoma (1 case) and carcinoma of the stomach (1 case). In this series, none of the metastases were from malignant melanoma or a renal n...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)81880-x
更新日期：1994-09-01 00:00:00
abstract：AIM:To present the clinical and radiological results of coil embolization in internal carotid artery (ICA) bifurcation aneurysms (BA). MATERIALS AND METHODS:The records of 65 patients with 66 ICA BA were retrieved from data prospectively accrued between September 1999 and July 2013. Clinical and morphological outcomes...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2014.01.017
更新日期：2014-06-01 00:00:00
abstract：AIM:To evaluate the safety and efficacy of computed tomography (CT)-guided percutaneous fine-needle aspiration biopsy (FNAB) of pancreatic masses that traverses the gastrointestinal tract or solid viscera. MATERIALS AND METHODS:From January 2002 to December 2012, 144 patients underwent 165 CT-guided biopsies of pancre...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2014.05.111
更新日期：2014-10-01 00:00:00
abstract：:Sodium picosulphate (Picolax) is widely used for bowel preparation prior to colonic investigation or surgery. The most troublesome side effect reported is headache, which has been thought to be due to dehydration. In a prospective randomized study we investigated the incidence of adverse effects in patients given Pico...
journal_title：Clinical radiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0009-9260(05)82911-3
更新日期：1994-01-01 00:00:00
abstract：AIM:To assess the rate of upgrade in our screening population to determine whether open excision biopsy of mucocoele-like lesions (MLL) is still required. MATERIALS AND METHODS:A retrospective review of the breast screening database from 1999-2014 was performed. RESULTS:MLL were identified on core biopsy in 113 women...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2017.06.012
更新日期：2017-11-01 00:00:00
abstract：:Liver transplantation continues to rise in frequency, with over 1,000 procedures performed in the UK in 2018. Complications are increasingly uncommon but when they occur, early recognition and intervention is vital to save grafts. Imaging after the perioperative period is often performed at patients' local hospitals m...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2020.06.007
更新日期：2020-11-01 00:00:00
