Abstract：
:Hepatocellular carcinoma (HCC) is one of the most frequent malignancies worldwide. A variety of pharmacological strategies has been evaluated in the treatment of HCC: classical chemotherapy, tamoxifen, octreotide, thymostimulin, pravastatin, (131)I-lipiodol as well as transarterial chemoperfusion (TAC) and chemoembolisation (TACE). TACE monotherapy or TACE combined with pravastatin resulted in a survival benefit of selected HCC patients. New strategies such as immunotherapy, antiangiogenic agents or cyclooxygenase inhibitors are under clinical investigation and might play a role in future therapies for HCC. Efficient strategies for the primary prevention of HCC are available and promising concepts in the secondary prevention have been reported.
journal_name
Zentralbl Chirjournal_title
Zentralblatt fur Chirurgieauthors
Spangenberg HC,Zuber-Jerger I,Thimme R,Blum HE,Von Weizsäcker Fdoi
10.1055/s-2003-44797subject
Has Abstractpub_date
2003-11-01 00:00:00pages
906-10issue
11eissn
0044-409Xissn
1438-9592journal_volume
128pub_type
杂志文章,评审abstract：BACKGROUND:This overview comments on gender-specific differences in incidence, risk factors and prognosis in patients with carcinoma of the liver, gallbladder, extrahepatic bile duct and pancreas. METHOD:For the literature review, the MEDLINE database (PubMed) was searched under the key words "liver cancer", "gallblad...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0034-1368231
更新日期：2014-04-01 00:00:00
abstract：:The onset of a malignant transformation in long-standing ulcerative colitis is difficult to predict. The value of the clinical and histomorphological parameters in current use is limited. It was thus aim of the present study to investigate the value of DNA-ploidy for the early detection of a malignant transformation i...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2000-10063
更新日期：2000-01-01 00:00:00
abstract：INTRODUCTION:Shot peening and grit blasting techniques are used to modify surfaces of hip endoprostheses. Alumina blasting techniques using highly pure corund (Al (2)O (3)) particles create a rough surface of Titanium implants to achieve a better osteointegration in cementless total hip arthroplasty. An increasing numb...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2005-836801
更新日期：2005-08-01 00:00:00
abstract：:For therapeutic recommendations three different kinds of scores are essential: 1. The severity scores for trauma; 2. Severity scores for mangled extremities; 3. Intensive care scores. The severity of polytrauma patients is measurable by the AIS, ISS, RTS, PTS and TRISS which is a combination of RTS, ISS, age, and mech...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1997-01-01 00:00:00
abstract：:Heavily injured patients, patients who underwent operations on pelvis, hips, abdomen or malignoma surgery, as well as gynaecology patients suffering from malignoma or previous deep femoral vein thrombosis in connection with pregnancy or obesity are at risk to suffer from pulmonary embolism with potentially lethal cour...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:A total of 85 skin biopsies taken from 23 pigs with experimental 3rd-degree burns was tested concerning the efficiency of the synthetic skin substitutes SYSpur-derm (GDR) and Epigard (USA). Both the materials have an excellent wound-cleansing-effect, show good adhesion to the wound surface and have no toxic or antigen...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:The surgical strategies in the treatment of operable breast cancer have changed basically within the last decades. Today the therapy of breast cancer is indicated by the individualization of the procedure in which the extent of the operative intervention is determined in first line in dependence of the clinical and hi...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：:Surgical education in the United States historically was influenced by the German educational system. Currently residents spend five years to become general surgeons. Education focuses on the teaching of surgical basic sciences and practical instruction in the operating room and at the bedside. Students interested in ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:The emergency room functions as a junction between preclinical and early clinical treatment of patients with multiple trauma and should have defined technical and room possibilities. The personal staff should continue resuscitation measures and perform clinical and technical diagnostic procedures according to trained ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Postoperative delayed graft function (DGF) after kidney transplantation is a risk factor for kidney failure and reduced kidney allograft survival after transplantation. The aim of this study was to measure the quantitative perfusion of kidney transplants during kidney transplantation and to investigate whether differe...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/a-0998-4424
更新日期：2020-02-01 00:00:00
abstract：:Between 1971 and 1988 74 operations for intestinal complications following radiotherapy were performed on 67 patients at the Second Surgical Department, University of Vienna. The lesions were located in the small bowel (n = 41) and in the sigmoid colon/rectum (n = 33). 98.5% of the patients were females, the most freq...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：INTRODUCTION:An adequate approach to surgically induced sepsis needs an early and targeted antibiotic therapy in addition to focus sanitation. The PCR-based LightCycler Septifast test can detect 90 % of the sepsis-associated microoganisms (e. g., Gram-positive, Gram-negative bacteria, fungi) within only a few hours. P...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-0028-1098776
更新日期：2009-06-01 00:00:00
abstract：:Nearly 200 clinical studies concerning perioperative antibiotic prophylaxis are compiled and evaluated by biometric methods, however without fulfilling the criteria of meta-analysis. Derived from its results it can be concluded, that this prophylaxis is indicated for the wound categories "clean" and "clean-contaminate...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:Like other industrial countries Germany experiences a significant increase of cancer prevalence. Recent advances in the treatment of various types of cancer resulted in prolonged survivaltimes of patients. Cancer--especially in advanced incurable stages--often is accompanied by severe pain. Therefore, the need for suf...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：:With the new method of gas exchange and dialysis carried out simultaneously with a standard dialysis module, for the first time normothermic ex-vivo whole blood perfusion of pig kidneys becomes practicable under nearly physiological conditions. To show the possibility of animal experiment replacements we use slaughter...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:The number of patients with a diagnosis of cancer is alarming: according to new figures from the Robert Koch Institute about 435 000 patients are diagnosed annually in Germany. 210 000 patients die annually of this diagnosis. Even if no significant progress in prevention has been achieved, in 2020 about 25 % more case...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0031-1283923
更新日期：2013-02-01 00:00:00
abstract：:The ancient method of larval therapy for treatment of acute and chronic infections has become a revival and a new dimension with introduction of the Biobag (Vitapad). With use of this therapy trauma patients suffering infectious complications can be treated very effective, which can reduce the overall time needed for ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2006-921510
更新日期：2006-04-01 00:00:00
abstract：:From 1956 to 1982, 4126 patients suffering from rectal cancer underwent surgery, 3229 of them had radical operations. The total postoperative mortality rate came up to 7.1% (n = 295) in the radical operated group it was 6.6% (n = 214). Between 1956 to 1982 continence preserving surgical procedures were constantly on t...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:This report presents late results of primary suture of fresh ruptures of knee ligaments. Considering the rapid development of knee surgery the control of a surgical procedure practically unchanged since 15 years seems necessary. On the basis of these late results immediate suture of ruptured knee ligaments is a useful...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The clinical experience with transmyocardial laser revascularization indicates that angina is relieved significantly, perfusion and treadmill tolerance are improved and hospital admissions are decreased. The exact mechanism for a laser revascularization linked improvement is still unknown. Transmyocardial laser revasc...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：BACKGROUND:Mucoceles of the appendix are rare. After appendectomy, mucoceles are detected with a frequency of 0.2 to 0.3 %. Both stenosing / obliterating processes and alterations of the epithelium (hyperplasia, mucinous cystadenoma, cystadenoma with uncertain malignant potential (UMP), mucinous cystadenocarcinoma lead...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-0029-1224563
更新日期：2010-08-01 00:00:00
abstract：:A villous giant adenoma of the duodenum was diagnosed in a 56-year-old female patient with uncharacteristic upper abdominal discomfort after multiple previous laparotomies for various indications. A partial pancreaticoduodenectomy was performed as radical oncological procedure since the dignity of the neoplasm was unc...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2001-11720
更新日期：2001-01-01 00:00:00
abstract：:This survey covers the problems of immunologic monitoring of patients and the spectrum of methods of diagnosing various types of immunopathological reactions. ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：INTRODUCTION:Etiology of osteochondral lesions of the talus remains uncertain, a myriad of treatment options exists. The purpose of this study is to evaluate the clinical and radiological results of fixation of osteochondral lesions of the talus using K-wires. An unstable osteochondral fragment or osteosclerotic change...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2004-832393
更新日期：2004-12-01 00:00:00
abstract：INTRODUCTION:Surgical therapy of Gastrointestinal stroma tumor (GIST) is the treatment of choice. Local resection will be carried out if technically possible. We describe the technique of laparoscopic wedge resection combined with intraoperative gastroscopy in order to achieve complete tumor resection. METHOD:We repor...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2006-933463
更新日期：2006-06-01 00:00:00
abstract：:According to the postoperative prophylaxis of thromboembolia a review of actual publications is given. The therapeutical problems of Coumarin, Dextran, Acetylsalicylic acid and low dosis Heparin were discussed. A final answer to the various questions can not be given. Concerning the prophylaxis low dosis Heparin seems...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1977-01-01 00:00:00
abstract：INTRODUCTION:In contrast to the USA, laparoscopic donor nephrectomy is rarely practised in German transplant centres. Safety concerns and difficulties with the learning curve of this advanced laparoscopic procedure are the main obstacles to the establishment of this operation. PATIENTS AND METHODS:From 1998-2005, we p...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2008-1004740
更新日期：2008-04-01 00:00:00
abstract：:Only in 2/3 out of a total of 33 patients suffering from renal artery stenosis surgery was indicated. Thrombendarterectomy and saphenous patch are the method of choice for reconstructive procedures. In 87% of successful reconstructions the functional result was satisfactory. The follow-up gave evidence of change to th...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:In the case of acute cholecystitis and chronic cholecystitis of lang standing, the inflammatory changes in Calot's triangle make the risk of damaging the bile duct during laparoscopic cholecystectomy particularly high. In view of the difficult anatomical situation in Calot's triangle, such patho-anatomical conditions ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The therapeutic effect of TGLVP a new hormonogen of vasopression in demonstrated in a pilot study: 9 patients suffering from bleeding oesophageal varices (in total 16) could be sufficiently treated by TGLVP, as well as 9 patients (in total 13) with abdominal haemorrhage of unknown aetiology and localization. Good resu...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
