Abstract:
:Sister chromatid exchanges (SCE) and chromosome aberrations (CA) were studied in the lymphocytes of 70 male agricultural workers occupationally exposed to several pesticides and 69 matched controls, without indication of exposure to pesticides, from 'El Maresme' (Barcelona, Spain), Comparison between both groups revealed that the individuals exposed to pesticides show substantial clastogenic effects in their lymphocytes without indication of increases in the basal frequency of SCE; moreover, these effects seem to be additive, increasing with the duration of exposure measured in years. When two confounding factors such as age and smoking habits are considered, we found that these factors increase significantly the expression of SCE although no effect was detected in the expression of CA.
journal_name
Mutagenesisjournal_title
Mutagenesisauthors
Carbonell E,Xamena N,Creus A,Marcos Rdoi
10.1093/mutage/8.6.511subject
Has Abstractpub_date
1993-11-01 00:00:00pages
511-7issue
6eissn
0267-8357issn
1464-3804journal_volume
8pub_type
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