Abstract:
:A substantial database on hprt mutant frequency in circulating T-cells derived from 153 normal humans was analysed to determine if any effect of alcohol consumption could be detected. Alcohol intake (as reported in a questionnaire completed at the time of the blood sample) ranged from 0 to 35+ units per week. Donors were classified into four groups, including total abstainers (n = 18); those who consumed less than the Royal College of Physicians guideline (men, 21 units; women, 14 units) (n = 113); those who consumed more than the guideline value (n = 12); and designated alcohol-dependent subjects (n = 10). No significant difference in mutant frequency between the four groups was found, nor was an overall correlation between alcohol consumption and mutant frequency seen.
journal_name
Mutagenesisjournal_title
Mutagenesisauthors
Cole J,Green MHdoi
10.1093/mutage/10.5.449subject
Has Abstractpub_date
1995-09-01 00:00:00pages
449-52issue
5eissn
0267-8357issn
1464-3804journal_volume
10pub_type
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