Evaluation of a urease-based confirmatory enzyme-linked immunosorbent assay for diagnosis of Neisseria gonorrhoeae.

Abstract:

:A new urease-based enzyme-linked immunosorbent assay utilizing novel monoclonal antibodies was evaluated for the culture confirmation of Neisseria gonorrhoeae, with 270 isolates of N. gonorrhoeae, 56 isolates of diverse Neisseria spp., and 29 Moraxella isolates. The test was highly specific (100.00%) and sensitive (97.83%). No cross-reactions were observed with any of the Neisseria or Moraxella isolates tested. Fifty percent (3 of 6) of the false-negative results were obtained with isolates of serovar IA-4, a serovar rarely encountered in North America.

journal_name

J Clin Microbiol

authors

Carballo M,Dillon JR,Lussier M,Milthorp P,Winston S,Brodeur B

doi

10.1128/JCM.30.8.2181-2183.1992

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

2181-3

issue

8

eissn

0095-1137

issn

1098-660X

journal_volume

30

pub_type

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