Evaluation of the polymerase chain reaction for diagnosis of herpes simplex virus encephalitis.

Abstract:

:Cerebrospinal fluid samples from 257 patients with suspected herpes simplex virus encephalitis were prospectively analyzed by herpes simplex virus polymerase chain reaction. The polymerase chain reaction indicated herpes simplex virus encephalitis in 9 serologically proven cases and in 14 additional patients. Increased polymerase chain reaction signals were observed together with more severe neurological symptoms (P < 0.01) and within the first days of acyclovir treatment (P < 0.05).

journal_name

J Clin Microbiol

authors

Puchhammer-Stöckl E,Heinz FX,Kundi M,Popow-Kraupp T,Grimm G,Millner MM,Kunz C

doi

10.1128/JCM.31.1.146-148.1993

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

146-8

issue

1

eissn

0095-1137

issn

1098-660X

journal_volume

31

pub_type

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