Action spectra of phthalocyanines with respect to photosensitization of cells.

abstract：:Ultraviolet radiation can inhibit immune responses locally as well as systemically. Such effects have been measured in animals and humans exposed to ultraviolet B (wavelength 280-315 nm) (UVB) and ultraviolet A (315-400 nm) (UVA). The precise wavelength dependence is important for the identification of possible molecu...

journal_title：Photochemistry and photobiology

authors： Garssen J,de Gruijl F,Mol D,de Klerk A,Roholl P,Van Loveren H

更新日期：2001-04-01 00:00:00

abstract：:The significance of human cutaneous pigmentation lies in its protective role against sun-induced DNA damage and photocarcinogenesis. Fair skin and red hair are characterized by a low eumelanin to pheomelanin ratio, and have been associated with increased risk of skin cancer. Cutaneous pigmentation is a complex genetic...

journal_title：Photochemistry and photobiology

authors： Dessinioti C,Antoniou C,Katsambas A,Stratigos AJ

更新日期：2011-09-01 00:00:00

abstract：:Aqueous solutions of KI were examined for use as chemical actinometers to measure 254 nm (germicidal) radiation. Irradiation results in electron ejection from iodide such that aqueous electrons and iodine atoms are formed. In the presence of N2O, an electron scavenger, recombination of these two reactive species is el...

journal_title：Photochemistry and photobiology

authors： Rahn RO

更新日期：1993-12-01 00:00:00

abstract：:Extracellular pH was measured continuously and noninvasively in hairless mice using a transcutaneous spectrofluorometric technique and a fluorescent pH probe, bis-carboxyethyl carboxyfluorescein (BCECF). The acid form of BCECF was injected intravenously. An optical fiber system excited the fluorescent probe at 450 and...

journal_title：Photochemistry and photobiology

authors： Russell DA,Pottier RH,Valenzeno DP

更新日期：1994-03-01 00:00:00

abstract：:Solar ultraviolet B (UVB) radiation has been shown to induce inflammation, DNA damage, p53 mutations and alterations in signaling pathways eventually leading to skin cancer. In this study, we investigated whether fisetin reduces inflammatory responses and modulates PI3K/AKT/NFκB cell survival signaling pathways in UVB...

journal_title：Photochemistry and photobiology

authors： Pal HC,Athar M,Elmets CA,Afaq F

更新日期：2015-01-01 00:00:00

abstract：:When Escherichia coli cells were irradiated by UVA in the presence of 6-mercaptopurine (6-MP) or 2-thiouracil (S2Ura), two kinds of repair-deficient strains of recA- and uvrA- were killed more efficiently than the parental wild-type strain having normal repair capacities. In addition, these agents with UVA exposure gr...

journal_title：Photochemistry and photobiology

authors： Komeda K,Iwamoto S,Kominami S,Ohnishi T

更新日期：1997-01-01 00:00:00

abstract：:The role of water molecules in spectral tuning of proteins has been left largely unexplored. This topic is important because changing hydrogen bond patterns during the activation process may lead to spectral shifts which can be of diagnostic value for the underlying structures. Arguments put forward in this article ar...

journal_title：Photochemistry and photobiology

authors： Sekharan S

更新日期：2009-03-01 00:00:00

abstract：:Phthalocyanine 4 (Pc 4) is a promising photosensitizer currently in clinical trials. Photobiological responses to Pc 4 photodynamic therapy (Pc 4-PDT) have been characterized extensively, but relatively little has been done to evaluate dose metrics for this sensitizer. We describe an irradiation-induced increase in fl...

journal_title：Photochemistry and photobiology

authors： Wang KK,Wilson JD,Kenney ME,Mitra S,Foster TH

更新日期：2007-09-01 00:00:00

abstract：:Cis-urocanic acid (UCA), formed in the epidermis by UV irradiation of trans-UCA, has been implicated as a mediator of the immunosuppression induced by UV exposure of the skin. This review covers recent work in which the wavelength dependence of cis-UCA formation, the interaction of UCA isomers with DNA, the effects of...

journal_title：Photochemistry and photobiology

authors： Norval M,Gibbs NK,Gilmour J

更新日期：1995-08-01 00:00:00

abstract：:The efficiency of ruthenium complexes for photosensitizing DNA damage depends on the oxidizing character of their ligands. Here we report on the difference in behavior of tris(2.2'-bipyrazyl)ruthenium(II) (Ru[bpz]3(2+)), tris(2,2'-bipyridyl)ruthenium(II) (Ru[bipy]3(2+)) and cis-dichlorobis (2,2'-bipyrazyl)ruthenium(II...

journal_title：Photochemistry and photobiology

authors： Vicendo P,Mouysset S,Paillous N

更新日期：1997-04-01 00:00:00

abstract：:Contribution of luciferin-regenerating enzyme (LRE) for in vitro recycling of D-luciferin has been reported. According to crystal structure of LRE, it is a beta-propeller protein which is a type of all β-protein architecture. In this overview, reinvestigation of the luciferase-based LRE assays and its function is repo...

journal_title：Photochemistry and photobiology

authors： Hosseinkhani S,Emamgholi Zadeh E,Sahebazzamani F,Ataei F,Hemmati R

更新日期：2017-03-01 00:00:00

abstract：:As our understanding of the role of UV in causing skin cancer continues to expand, researchers and clinicians must continue to remain up to date on the various means by which UV exposure can be quantified. The purpose of this article was to review the current methods used to measure lifetime exposure to UV and to summ...

journal_title：Photochemistry and photobiology

authors： Worswick SD,Cockburn M,Peng D

更新日期：2008-11-01 00:00:00

abstract：:Herpes simplex virus (HSV) normally causes vescular lesions on mucocutaneous surfaces but can also cause encephalitis. The virus can reactivate from the latent state in neurons to form recrudescent lesions. One common stimulus for reactivation is exposure to sunlight. In the present study, the effects of irradiating r...

journal_title：Photochemistry and photobiology

authors： Garssen J,van der Molen R,de Klerk A,Norval M,van Loveren H

更新日期：2000-11-01 00:00:00

abstract：:Bacteriochlorophyll (BChl) e was coassembled with BChl c in Triton X-100 micelles in aqueous solutions. The Qy absorption bands of the coaggregates were positioned between those of aggregates consisting solely of BChl c or e. The electronic absorption spectra of the coaggregates could not be reproduced by linear combi...

journal_title：Photochemistry and photobiology

authors： Saga Y,Saiki T,Takahashi N,Shibata Y,Tamiaki H

更新日期：2014-05-01 00:00:00

abstract：:Here, 10 guidelines are presented for a standardized definition of type I and type II photosensitized oxidation reactions. Because of varied notions of reactions mediated by photosensitizers, a checklist of recommendations is provided for their definitions. Type I and type II photoreactions are oxygen-dependent and in...

journal_title：Photochemistry and photobiology

authors： Baptista MS,Cadet J,Di Mascio P,Ghogare AA,Greer A,Hamblin MR,Lorente C,Nunez SC,Ribeiro MS,Thomas AH,Vignoni M,Yoshimura TM

更新日期：2017-07-01 00:00:00

abstract：:We have investigated the factors that affect the virucidal activity of methylene blue (MB) photosensitization. The M13 bacteriophage was more rapidly inactivated at higher temperatures (6 degrees C < 24 degrees C < 38 degrees C). Rate constants for inactivation were 0.072, 0.139 and 0.260 (log10 inactivation)/ (J/cm2)...

journal_title：Photochemistry and photobiology

authors： Abe H,Wagner SJ,Kuwabara M,Kamo N,Ikebuchi K,Sekiguchi S

更新日期：1997-05-01 00:00:00

abstract：:Synthesis of extracellular matrix (ECM) proteins and their degradation by matrix metalloproteinases (MMP) are part of the dermal remodeling resulting from chronic exposure of skin to ultraviolet radiation (UVR). We have compared two alternative mechanisms for these responses, namely, a direct mechanism in which UV-B o...

journal_title：Photochemistry and photobiology

authors： Kossodo S,Wong WR,Simon G,Kochevar IE

更新日期：2004-01-01 00:00:00

abstract：:The immunological consequences of exposure to UVA (320-400 nm) radiation are unclear. This study describes the relationship between the generation of epidermal cis-urocanic acid and the ability to respond to a contact-sensitizing agent, in hairless mice exposed to different UV radiation sources, which incorporate succ...

journal_title：Photochemistry and photobiology

authors： Reeve VE,Boehm-Wilcox C,Bosnic M,Cope R,Ley RD

更新日期：1994-09-01 00:00:00

abstract：:Targeted mutagenesis and gene knock-out can be mediated by triple helix-forming oligonucleotides (TFO) linked to mutagenic agents, such as psoralen. However, this strategy is limited by the availability of homopurine/homopyrimidine stretches at or near the target site because such sequences are required for high-affin...

journal_title：Photochemistry and photobiology

authors： Raha M,Lacroix L,Glazer PM

更新日期：1998-03-01 00:00:00

abstract：:The mutant T203V of the light driven chloride pump halorhodopsin from Halobacterium salinarum was crystallized and the X-ray structure was solved at 1.6 angstroms resolution. The T203V structure turned out to be nearly identical to the wild type protein with a root mean square deviation of 0.43 angstroms for the carbo...

journal_title：Photochemistry and photobiology

authors： Gmelin W,Zeth K,Efremov R,Heberle J,Tittor J,Oesterhelt D

更新日期：2007-03-01 00:00:00

abstract：:Chaetopterus variopedatus has been studied for over a century in terms of its physiology, ecology and life history. One focus of research is on its intrinsic bioluminescent emissions, which can be observed as a blue light emitted from the extremities of individual body segments, or as a secreted mucus. Even though res...

journal_title：Photochemistry and photobiology

authors： Mirza JD,Migotto ÁE,Yampolsky IV,de Moraes GV,Tsarkova AS,Oliveira AG

更新日期：2020-07-01 00:00:00

abstract：:Urinary cytology is a noninvasive and unconstraining technique for urothelial cancer diagnosis but lacks sensitivity for detecting low-grade lesions. In this study, the fluorescence properties of classical Papanicolaou-stained urothelial cytological slides from patients or from cell lines were monitored to investigate...

journal_title：Photochemistry and photobiology

authors： Steenkeste K,Lécart S,Deniset A,Pernot P,Eschwège P,Ferlicot S,Lévêque-Fort S,Briandet R,Fontaine-Aupart MP

更新日期：2007-09-01 00:00:00

abstract：:Limited trypsinization of large pea (Pisum sativum cv. Alaska) phytochrome and subsequent size-exclusion chromatography (SEC) in 0.1 M Na phosphate, pH 7.8, yielded a high-molecular-mass aggregate of tryptic fragments of phytochrome. Further SEC in 0.1 M Tris-HCl, pH 7.5, plus various concentrations of NaSCN, indicate...

journal_title：Photochemistry and photobiology

authors： Yamamoto KT,Tokutomi S

更新日期：1989-07-01 00:00:00

abstract：:Photolysis of ester 1 in argon-saturated methanol and acetonitrile does not produce any product, whereas irradiation of 1 in oxygen-saturated methanol yields peroxide 2. Laser flash photolysis studies demonstrate that 1 undergoes intramolecular H atom abstraction to form biradical 3 (λmax ~340 nm), which intersystem c...

journal_title：Photochemistry and photobiology

authors： Das A,Lao EA,Gudmundsdottir AD

更新日期：2016-05-01 00:00:00

abstract：:UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation, which triggers a wide range of cellular responses involved in photomorphogenesis and photoprotection. Two recent crystal structures of ...

journal_title：Photochemistry and photobiology

authors： Yang X,Montano S,Ren Z

更新日期：2015-09-01 00:00:00

abstract：:Photosensitizer (PS)-antibody conjugates (photoimmunoconjugates, PICs) enable cancer cell-targeted photodynamic therapy (PDT). Nonspecific chemical bioconjugation is widely used to synthesize PICs but gives rise to several shortcomings. The conjugates are heterogeneous, and the process is not easily reproducible. More...

journal_title：Photochemistry and photobiology

authors： Sadiki A,Kercher EM,Lu H,Lang RT,Spring BQ,Zhou ZS

更新日期：2020-05-01 00:00:00

abstract：:Macroalgae distributed in intertidal zones experience a series of environmental changes, such as periodical desiccation associated with tidal cycles, increasing CO2 concentration and solar UVB (280-315 nm) irradiance in the context of climate change. We investigated how the economic red macroalga, Pyropia haitanensis,...

journal_title：Photochemistry and photobiology

authors： Xu J,Gao K

更新日期：2015-11-01 00:00:00

abstract：:Photodynamic therapy (PDT) with photosensitizer verteporfin is a clinically approved vascular disrupting modality that is currently in clinical trial for cancer treatment. In this study, we evaluated PDT in combination with either mTORC1 inhibitor rapamycin or mTORC1/C2 dual inhibitor AZD2014 for therapeutic enhanceme...

journal_title：Photochemistry and photobiology

authors： Kraus D,Palasuberniam P,Chen B

更新日期：2020-03-01 00:00:00

abstract：:From June to September 2005, we carried out experiments to determine the ultraviolet radiation (UVR) -induced photoinhibition of summer phytoplankton assemblages from a coastal site of the South China Sea. Variability in taxonomic composition was determined throughout the summer, with a peak chlorophyll a (chl a appro...

journal_title：Photochemistry and photobiology

authors： Gao K,Li G,Helbling EW,Villafañe VE

更新日期：2007-07-01 00:00:00

abstract：:We have demonstrated that it is possible to launch UVC LED light into bacterial contaminated polymer tubes/catheters and disinfect the intraluminal space of these tubes. This can be achieved by UVC treatment of the catheters on a regular basis. Catheters are in the distal end equipped with an exit hole for administrat...

journal_title：Photochemistry and photobiology

authors： Bak J,Jørgensen TM,Helfmann J,Gravemann U,Vorontsova I

更新日期：2011-03-01 00:00:00