Abstract:
:Rat hepatic hydroxysteroid sulfotransferase with sulfoconjugates androsterone (androsterone-sulfating sulfotransferase) is an oligomer consisting of several subunits with distinct pI values but with the same molecular mass (pI variants). N-terminal amino acid sequences of the pI variants are all identical. The enzyme is exclusively present in the liver, in which its lobular localization is sex-dependent. The localization of the enzyme is markedly different from that of an isoenzyme of phenol sulfotransferase. In weanling and adult female rats, the relative abundance of the pI variants is different. During development from weanling stage to adulthood, the amounts of acidic variants increase, whereas the relative levels of alkaline variants remain constant.
journal_name
Chem Biol Interactjournal_title
Chemico-biological interactionsauthors
Homma H,Nakagome I,Kamakura M,Hirota M,Takahashi M,Matsui Mdoi
10.1016/0009-2797(94)90049-3subject
Has Abstractpub_date
1994-06-01 00:00:00pages
15-24issue
1-3eissn
0009-2797issn
1872-7786pii
0009-2797(94)90049-3journal_volume
92pub_type
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journal_title:Chemico-biological interactions
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journal_title:Chemico-biological interactions
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journal_title:Chemico-biological interactions
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journal_title:Chemico-biological interactions
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journal_title:Chemico-biological interactions
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journal_title:Chemico-biological interactions
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