Abstract:
:TPS was determined by immunohistochemistry in 44 different tissues (normal and pathological) from various organs such as cervix, endometrium, breast, stomach, bowel and bladder. TPS was expressed in several physiologic situations: in different phases of the endometrial cycle and in cervical metaplasia. In other organs such as the breast and the bladder this antigen shows its highest expression in invasive neoplasias. Therefore, it could be utilized in the follow-up of these neoplasias.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
Giovagnoli MR,Valli C,Vecchione A,Vecchione Asubject
Has Abstractpub_date
1994-03-01 00:00:00pages
635-41issue
2Beissn
0250-7005issn
1791-7530journal_volume
14pub_type
杂志文章abstract:BACKGROUND/AIM:Omega 3 polyunsaturated fatty acids (PUFAs) have been shown to inhibit the induction and progression of many tumor types. The aim of this study was to determine the anticancer effect of docosahexaenoic acid monoglyceride (MAG-DHA) alone and in combination with the chemotherapeutic agent carboplatin (CBT)...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.12048
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:As a majority of ovarian cancer patients will ultimately develop recurrent disease, there is an urgent need for alternative or additional approaches in the treatment of this cancer. MATERIALS AND METHODS:The antitumour effect of i.p. administered cisplatin, liposomal muramyltripeptide phosphatidylethanulami...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Therapy for patients with hepatic metastases from colorectal cancer (CRC) remains controversial and may be improved by regional oxaliplatin which proved to be effective when administered systemically to patients with advanced CRC. METHODS:During the current study, which aims to determine the maximum tolerat...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Sunitinib is a tyrosine kinase inhibitor (TKI) targeting tumour angiogenesis in patients with advanced renal cell carcinoma (RCC). Currently no universally agreed model exists correlating the expression of angiogenesis markers with the success of treatment. PATIENTS AND METHODS:We retrospectively analysed a...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.11315
更新日期:2017-01-01 00:00:00
abstract::It has been shown recently that various myeloid leukemia cells can be induced by numerous compounds to differentiate terminally into non-growing mature cells. Furthermore, some of these compounds have been found to be clinically useful for the therapy of certain types of myeloid leukemia. To improve this new method of...
journal_title:Anticancer research
pub_type: 杂志文章,评审
doi:
更新日期:1994-05-01 00:00:00
abstract::The purpose of our study was to evaluate the presence of anatomical and functional damage to the afferent and sensorial fibres using the Neurometer CPT test. A questionnaire regarding pain was sent to 300 women who had undergone surgery six months earlier. Out of 300 patients 67 did not respond; 105 experienced no pai...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::The MIB1 monoclonal antibody which is used as a marker of cell proliferation was studied by immunohistochemistry on formalin-fixed and paraffin embedded biopsy specimens of lymph nodes in 40 high- and 46 lowgrade cases of non-Hodgkin's lymphomas (NHL) classified according to the Kiel classification. All cases were fou...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND/AIM:Since antigenic peptides of the cancer-associated antigens presented on human leukocyte antigen (HLA) molecules are recognized by specific cytotoxic T-lymphocytes, they have the potential to becoming effective peptide vaccines for cancer immunotherapy. MATERIALS AND METHODS:Peptides binding to HLA-A*020...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:The major side-effects of bevacizumab in glioma treatment are venous thromboembolic events (VTE). We retrospectively evaluated factors potentially predictive of thromboembolic events. PATIENTS AND METHODS:Bevacizumab, alone or in combination with chemotherapy was used as salvage therapy for recurrence in ma...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2013-05-01 00:00:00
abstract::A brief review summarizing the relationships that exist between the DEK protein and gene regulation, oncogenesis and AIDS. ...
journal_title:Anticancer research
pub_type: 杂志文章,评审
doi:
更新日期:2003-05-01 00:00:00
abstract::The antineoplastic drug 4'-iodo-4'-deoxydoxorubicin (IDX), a new halogenated anthracycline (1), was examined as a differentiation inducing agent on the human neuroblastoma cell lines TS12 and SK-N-MC. IDX induced morphological and biochemical differentiation and growth inhibition. The effect of a combined treatment of...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND/AIM:To study the changes of glioblastoma multiforme during chemoradiotherapy (CRT) and to evaluate the impact of changes on dosimetry and clinical outcomes. PATIENTS AND METHODS:Forty-three patients underwent volumetric imaging-based replanning. Prognostic factors and gross tumor volume changes in relation ...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.14425
更新日期:2020-08-01 00:00:00
abstract::Chloroethyl-nitrosourea is a potent chemotherapeutic agent for brain tumors. However, acquired resistance to this drug has become a serious problem for the treatment of patients. Previously, we established an animal model resistant to nitrosourea (Anticancer Res 19: 5313-5318, 1999). In this study, we evaluate the eff...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract::The stems of Bougainvillea spectabillis Wild (Nyctaginaceae) have been used in folk medicine for hepatis, and spinasterol and quercetin were isolated and characterized from the plant leaves in this study. These constituents have not been previously isolated from Bougainvillea spectabillis W. Quercetin, the flavonoid, ...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract::Several lines of evidence have postulated that reduction in the activity of lipoprotein lipase (LPL) is involved in cachexia induction in cancer patients. Recently we have demonstrated that murine melanoma B16 has the ability to reduce the LPL activity and thereby induce cachexia symptoms in mice following intraperito...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:UNLABELLED:The aim of the present study was to evaluate the effectiveness and safety of hepatic re-resection for breast cancer liver metastases. PATIENTS AND METHODS:Between January 2004 and December 2014 seven patients were submitted to liver re-resection for breast cancer liver metastases at our Center. The main inc...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND/AIM:The differentiation of the mouse breast epithelial cell line HC11 is known to require confluence as well as the addition of hydrocortisone, insulin and prolactin. MATERIALS AND METHODS:Since confluence, which triggers the engagement of the cell-to-cell adhesion molecule E-cadherin, induces a dramatic in...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.13401
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND/AIM:The presence of ascites in ovarian cancer patients is considered a negative prognostic factor. The underlying mechanisms are not clearly understood. MATERIALS AND METHODS:The amount of ascites was evaluated, preferably, using diffusion-weighted MRI at primary diagnosis in a retrospective cohort of 214 w...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.13800
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND/AIM:Only 30-50% of patients with sentinel lymph node (SLN) metastases present with further axillary lymph node metastases. Therefore, up to 70% of patients with positive SLN are overtreated by axillary dissection (AD) and may suffer from complications such as sensory disturbances or lymphedema. According to ...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.12694
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND/AIM:The present retrospective study was conducted to measure Wilms' tumor-1 (WT1) mRNA levels in the peripheral blood of patients with acute myeloid leukemia (AML) in order to examine any association with the clinical outcomes. PATIENTS AND METHODS:A total of 58 AML patients were evaluated retrospectively i...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2013-08-01 00:00:00
abstract::A universal intracellular factor, the "M phase-promoting factor" (MPF), triggers the G2/M transition of the cell cycle in all organisms. In late G2, it is present as an inactive complex of tyrosine-phosphorylated p34cdc2 and unphosphorylated cyclin Bcdc13. In M phase, its activation as an active MPF displaying histone...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::Glioblastoma multiforme (GBM), a grade IV glioma, appears to harbor therapy-resistant cancer stem cells (CSCs) that are the major cause of recurrence. All-trans retinoic acid (ATRA), a derivative of retinoid, is capable of differentiating a variety of stem cells, as well as normal neural progenitor cells, and down-reg...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND/AIM:Invasive bladder cancer mortality remains high despite progresses made in early diagnosis and surgical procedures. Thus, there is a need to define new markers for bladder cancer. CLIC1 has not been previously studied in bladder cancer and thus, we aimed to assess its immunohistochemical expression in rel...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.14710
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:The concepts of vasculogenic mimicry and mosaic vessels have been proposed as novel modes of tumour neovascularisation. However, the presence and significance of these types of neovascularisation remain unclear. MATERIALS AND METHODS:ECV304 human bladder carcinoma cells were used to determine how tumour cel...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract:AIMS AND BACKGROUND:Radiation therapy holds a fundamental role in oncological emergencies such as superior vena cava syndrome, spinal cord compression and endocranial hypertension. The purpose of our study was, by comparing schedules of treatment, to confirm the efficacy of hypofractionated radiation therapy. METHODS:...
journal_title:Anticancer research
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::The cyclin-dependent kinase inhibitor (CDK1) p27(kip1) is a negative regulator of cell cycling and has antitumor effects. In our previous study, the recombinant adenovirus expressing wild-type p27(kip1) (Adp27-wt) induced cell cycle arrest and apoptosis, and proved that p27 is a tumor suppressor gene like p53. Another...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
abstract:AIM:The aim of this study was to investigate if Linomide affects growth and spread of a rat liver tumour when given alone and in combination with interstitial laser thermotherapy (ILT). MATERIALS AND METHODS:Experiments were performed in Wistar rats using a dimethyl-hydrazine-induced adenocarcinoma implanted into the ...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Between January 1996 and June 2000, 192 men with prostate cancer underwent radical retropubic prostatectomy (RP) and bilateral pelvic node dissection in 26 centers participating in the Italian randomized prospective TAP study. The reviewing pathologist evaluated 145 RP specimens. Seventy-five cases had not been treate...
journal_title:Anticancer research
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:This was a validation study of a regional register of oral cancer in Örebro, Sweden. The purpose was to assess the rate of errors in baseline, and treatment, and the completeness and accuracy of data on recurrences. MATERIALS AND METHODS:A total of 653 cases with squamous cell cancer in the oral cavity were...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.13109
更新日期:2019-01-01 00:00:00
abstract::The effect of alpha-Interferon (alpha-IFN), gamma-interferon (gamma-IFN), tumor necrosis factor alpha (TNF-alpha) and interleukin-2 (Il-2) on growth of two renal cancer cell lines (DNT-11, HTB-44) was studied. Cell proliferation was measured by a tetrazolium based microculture assay (MTT) after incubation of tumor cel...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00