Abstract:
:Sixty patients, scheduled for Caesarean section were randomly allocated to receive by the epidural route in a double-blind fashion one of the following patient-controlled analgesia mixtures for the relief of postoperative pain: sufentanil 2 micrograms.ml-1 in 0.9% sodium chloride, sufentanil 2 micrograms.ml-1 + adrenaline 2.5 micrograms.ml-1, or sufentanil 2 micrograms.ml-1 + clonidine 3 micrograms.ml-1. Patient-controlled analgesia settings were a basal infusion rate of 2.5 ml.h-1, an incremental dose of 2.5 ml, a lockout interval of 10 min and a 1-h limit of 10 ml. Whereas patient demographics and pain scores between the groups were not different, the 24-h consumption of sufentanil was significantly lower in the groups receiving a combination (167.5 SD 45 and 139.1 SD 31.9 micrograms for the adrenaline and clonidine groups respectively) as compared to the plain sufentanil regimen (208.2 SD 38.9 micrograms). Although sufentanil requirements were the lowest in the clonidine admixture group, there were no differences with regard to sedation as compared to the plain sufentanil group. The quality of sleep appeared to be significantly better in the sufentanil/adrenaline group despite a significantly lower degree of sedation and higher incidence of pruritus. Treatment of pruritus with naloxone did not seem to influence the quality of analgesia.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Vercauteren MP,Vandeput DM,Meert TF,Adriaensen HAdoi
10.1111/j.1365-2044.1994.tb04447.xsubject
Has Abstractpub_date
1994-09-01 00:00:00pages
767-71issue
9eissn
0003-2409issn
1365-2044journal_volume
49pub_type
临床试验,杂志文章,随机对照试验相关文献
ANAESTHESIA文献大全abstract::We assessed the effectiveness of early patient-controlled oral analgesia compared with parenteral analgesia in a randomised controlled non-inferiority trial of women undergoing elective caesarean section under regional anaesthesia. Seventy-seven women received multimodal paracetamol, ketoprofen and morphine analgesia....
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/anae.13406
更新日期:2016-05-01 00:00:00
abstract::Peripherally inserted central catheters are often positioned blindly in the central circulation, and this may result in high malposition rates, especially in critically ill patients. Recently, a new technology has been introduced (Sherlock 3CG Tip Positioning System) that uses an electro-magnetic system to guide posit...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.12785
更新日期:2014-12-01 00:00:00
abstract::A case is presented of a mother with unanticipated profound thrombocytopenia who received a continuous epidural anaesthetic for labour. No neurological sequelae or excessive bleeding occurred. It is clear, after a review of the literature, that more information is needed to define the lower limits of platelet count at...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1989.tb09270.x
更新日期:1989-09-01 00:00:00
abstract::Ten patients received increasing doses of pipecuronium at induction of anaesthesia. A dose response relationship was then constructed from which ED90 and ED95 values were measured as 43.4 micrograms.kg-1 and 50.5 micrograms.kg-1 respectively. A further 30 patients received pipecuronium in a dose sufficient to produce ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1993.tb06899.x
更新日期:1993-03-01 00:00:00
abstract::Sixty-seven patients undergoing general anaesthesia for exodontia as outpatients were studied in order to measure the levels of oxygen saturation. Both the anaesthesia and extractions were performed by fourth year dental undergraduates working under direct supervision. Falls in oxygen saturation in excess of 5% were f...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1984.tb08937.x
更新日期:1984-11-01 00:00:00
abstract::A 38-year-old woman developed symptoms of anaphylactic shock after intravenous atropine and required adrenaline to maintain perfusion pressure. A strongly positive response was obtained on intradermal testing. The Prausnitz-Kuestner test was also positive, which indicated the presence of drug specific IgE antibodies. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1988.tb05661.x
更新日期:1988-11-01 00:00:00
abstract::Functional capacity is an integral component of the pre-operative evaluation of the cardiac patient for non-cardiac surgery. Stair climbing capacity has peri-operative prognostic importance. It may predict survival after lung resection and complications after major non-cardiac surgery. However, stair climbing cannot d...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.2005.04181.x
更新日期:2005-06-01 00:00:00
abstract::Opioid induced respiratory depression is potentially fatal. The aim of this study was to validate a monitoring system that could be used to assess respiratory depression in postoperative patients. The hypercapnic ventilatory response was estimated non-invasively in 12 volunteers. In two steps, we tested a system which...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2005.04153.x
更新日期:2005-05-01 00:00:00
abstract::The action of orphenadrine when given towards the end of a general anaesthetic is described. It is shown to delay the need for postoperative analgesia and extend the analgesic action of papaveretum. ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1979.tb06311.x
更新日期:1979-03-01 00:00:00
abstract::The deployment of physician-led pre-hospital enhanced care teams capable of critical care interventions at the scene of injury may confer a survival benefit to victims of major trauma. However, the evidence base for this widely adopted model is disputed. Failure to identify a clear survival benefit has been attributed...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.14501
更新日期:2019-04-01 00:00:00
abstract::To date, the dosing of sugammadex is based on real body weight without taking fat content into account. We compared the reversal of profound rocuronium-induced neuromuscular blockade in morbidly obese patients using doses of sugammadex based on four different weight corrections. One hundred morbidly obese patients, sc...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2011.06782.x
更新日期:2011-08-01 00:00:00
abstract::Forty-five operative procedures were performed in 32 patients with Down's syndrome at the Royal Alexandra Hospital for Children, Sydney in a single year recently. Atropine premedication was administered to 25 patients with Down's syndrome on 38 occasions. Three dosage regimes of atropine were used: 20 micrograms/kg, 1...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1983.tb12253.x
更新日期:1983-09-01 00:00:00
abstract::Posterior transversus abdominis plane blocks have been reported to be an effective method of providing analgesia after lower abdominal surgery. We compared the efficacy of a novel technique of providing continuous transversus abdominis plane analgesia with epidural analgesia in patients on an enhanced recovery program...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/anae.12546
更新日期:2014-04-01 00:00:00
abstract::Propofol has been shown to cause pain on injection. This study investigated the effect of warming propofol to 37 degrees C on the pain of intravenous injection. One hundred and one women on outpatient gynaecology lists were allocated to receive propofol either at room temperature or at 37 degrees C. Warming propofol d...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1996.tb07802.x
更新日期:1996-05-01 00:00:00
abstract::One hundred patients undergoing microsurgery of the ear were anaesthetised using thiopentone, nitrous oxide, oxygen and either halothane or enflurane with spontaneous respiration. Blood pressure was reduced to approximately 70 mmHg by the use of hypotensive agents. The efficacy of halothane and enflurane in producing ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1982.tb01718.x
更新日期:1982-10-01 00:00:00
abstract::The ability of the Transit-time Ultrasonic Breath Analyser (TUBA, GHG Medical Electronics GMBH, Zürich, Switzerland) to measure peak flow and tidal volume in the laboratory was tested using a variety of flow and pressure conditions, chosen to simulate the respiratory patterns of patients receiving mechanical ventilato...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1995.tb05999.x
更新日期:1995-05-01 00:00:00
abstract::We report 13 cases of presumed rocuronium-induced anaphylaxis in which sugammadex was administered with the intention of reversing the immunological reaction. Of these 13 cases, eight (62%) were later confirmed to be type-1 hypersensitivity reactions to rocuronium, three (23%) were triggered by an antibiotic and two (...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.13178
更新日期:2015-11-01 00:00:00
abstract::A case is described of prolonged neuromuscular block in a patient who was given the muscle relaxant vecuronium followed by bolus injections of the antibiotics gentamycin and clindamycin. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1987.tb04111.x
更新日期:1987-08-01 00:00:00
abstract::One hundred and ninety-eight children, aged 3 to 12 years, who were scheduled for tonsillectomy were randomly allocated to receive either diclofenac 1.0 mg.kg-1 or papaveretum 0.2 mg.kg-1 by intramuscular injection after induction of anaesthesia. There were no significant differences between the treatment groups in op...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-02-01 00:00:00
abstract::The anaesthetic management of patients in haemorrhagic shock is described. The principles are those of initial resuscitation with electrolyte solutions and alleviation of metabolic acidosis, combined with early induction of anaesthesia to permit control of bleeding as soon as possible. The anaesthetic technique depend...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1975.tb00921.x
更新日期:1975-09-01 00:00:00
abstract::The Triservice anaesthetic apparatus is a draw-over using ambient air as the primary carrier gas. Its modules are a self-inflating bag, a vaporiser, a supplementary oxygen regulator and a ventilator; each is described. The outputs of halothane and trichloroethylene were measured with changes of temperature, continuous...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1981.tb08696.x
更新日期:1981-12-01 00:00:00
abstract::We report two patients with difficult airways who underwent tracheal intubation using the new fibreoptic intubating Laryngeal Mask Airway CTrach. The imaging technology of the LMA-CTrach was decisive in the management of these two patients. The first patient had lingual tonsillar hyperplasia, and an omega-shaped retro...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2006.04660.x
更新日期:2006-06-01 00:00:00
abstract::We report the case of a 14-year-old girl who deliberately ingested 8-9 g of dapsone and presented with severe methaemoglobinaemia and altered mental status. Prompt treatment with repeated doses of methylene blue and organ support brought about control of the methaemoglobinaemia and averted organ failure. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1997.98-az0094b.x
更新日期:1997-04-01 00:00:00
abstract::We measured total and free plasma concentrations of ropivacaine following high-volume, high-dose local infiltration analgesia in 28 patients aged 65 years or over undergoing unilateral total knee arthroplasty. Patients received infiltration of ropivacaine 400 mg followed by infusion at 20 mg.h(-1) through an intra-art...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.13017
更新日期:2015-07-01 00:00:00
abstract::In a well-defined fast-track setup for total hip and knee arthroplasty, with a multimodal analgesic regimen consisting of intra-operative local anaesthetic infiltration and oral celecoxib, gabapentin and paracetamol for 6 days postoperatively, we conducted a prospective, consecutive, observational study. The purpose w...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2008.05831.x
更新日期:2009-05-01 00:00:00
abstract::The effects of a sedative infusion of propofol on haemodynamics and oxygen transport were examined in critically ill adult patients. Ten patients receiving mechanical ventilation for treatment of septic shock and respiratory failure were given a decreasing rate propofol infusion designed to achieve and maintain a stab...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1994.tb03517.x
更新日期:1994-06-01 00:00:00
abstract::A new approach to the internal jugular vein is described which keeps the head and neck in the neutral position and uses bony and cartilaginous landmarks for guidelines. Venous puncture is made along an axial line drawn superiorly from the lateral edge of the bony depression caused by the insertion of the sternocleidom...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1994.tb03421.x
更新日期:1994-03-01 00:00:00
abstract::Eighteen patients with advanced cystic fibrosis complicated by pneumothorax required either pleurectomy or abrasion pleurodesis. Anaesthesia with nitrous oxide and oxygen was combined with controlled ventilation to both lungs, usually through a double lumen endobronchial tube. Spontaneous ventilation was restored at t...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1984.tb06473.x
更新日期:1984-07-01 00:00:00
abstract::Most anaesthetic equipment needs to be modified to fulfil anti-pollution recommendations. A method of modifying a Cape-Waine Anaesthetic Ventilator is described in detail showing what parts need to be replaced or removed. A list of the new parts required together with their cost is given and the modification can be ma...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1977.tb09968.x
更新日期:1977-11-01 00:00:00
abstract::Doxacurium was administered to 50 adult patients for determination of potency (n = 10), onset and duration of clinical relaxation (n = 40). Cumulative dose-response showed the ED95 to be 33.24 micrograms.kg-1 (95% confidence limits 27.4-39.3). Doxacurium 33 micrograms.kg-1 was then administered to four groups of 10 pa...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb02322.x
更新日期:1992-07-01 00:00:00