The safety of atropine premedication in children with Down's syndrome.

Abstract:

:Forty-five operative procedures were performed in 32 patients with Down's syndrome at the Royal Alexandra Hospital for Children, Sydney in a single year recently. Atropine premedication was administered to 25 patients with Down's syndrome on 38 occasions. Three dosage regimes of atropine were used: 20 micrograms/kg, 12 micrograms/kg, both intramuscularly, and 10 micrograms/kg intravenously. There was no statistically significant difference in the alteration of heart rate for the three dosage groups of atropine used when children with Down's syndrome were compared with weight-matched control children having similar operative procedures performed.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Wark HJ,Overton JH,Marian P

doi

10.1111/j.1365-2044.1983.tb12253.x

subject

Has Abstract

pub_date

1983-09-01 00:00:00

pages

871-4

issue

9

eissn

0003-2409

issn

1365-2044

journal_volume

38

pub_type

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