Abstract:
:Hypochlorhydric states such as atrophic gastritis and partial gastrectomy have long been known to cause iron deficiency anemia. However, studies to date have failed to show a similar association with omeprazole, a proton pump inhibitor that also produces achlorhydria. These studies, however, have primarily involved nonanemic, iron-replete individuals. The effect of the drug has not been studied in patients with established iron deficiency, and to our knowledge the patients presented here are the first of their kind to be reported. Our observations support the probability that the profound hypochlorhydria induced by omeprazole may indeed impair the optimal absorption of orally administered iron in iron-deficient individuals, precluding them from obtaining therapeutically adequate amounts to establish the positive balance necessary for the resolution of anemia and the replenishment of stores. The possible explanations for this phenomenon are also discussed.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Sharma VR,Brannon MA,Carloss EAdoi
10.1097/01.SMJ.0000110405.63179.69subject
Has Abstractpub_date
2004-09-01 00:00:00pages
887-9issue
9eissn
0038-4348issn
1541-8243journal_volume
97pub_type
杂志文章abstract::The right ventricle is not normally displayed by studies with thallium 201 in patients at rest, but it can be shown by thallium 201 myocardial scintigraphy with pressure or volume overload of the right ventricle and with right ventricular hypertrophy. We sought to determine the frequency of right ventricular demonstra...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198512000-00009
更新日期:1985-12-01 00:00:00
abstract::Chronic metformin use results in vitamin B12 deficiency in 30% of patients. Exhaustion of vitamin B12 stores usually occurs after twelve to fifteen years of absolute vitamin B12 deficiency. Metformin has been available in the United States for approximately fifteen years. Vitamin B12 deficiency, which may present with...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181ce0e4d
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:Total annual costs for syncope-related hospitalizations were $2.4 billion in 2000. The aim of this study was to examine the type and number of tests ordered for patients admitted with syncope and whether these tests helped establish the cause. METHODS:We studied the records of 1038 patients coded as "syncop...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000184
更新日期:2014-11-01 00:00:00
abstract::Rocky Mountain spotted fever is a serious acute systemic illness frequently complicated by cardiac involvement. To evaluate the spectrum of myocardial dysfunction, we obtained M-mode echocardiograms on nine consecutive patients with Rocky Mountain spotted fever within 72 hours of admission. Seven of the nine patients ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198409000-00019
更新日期:1984-09-01 00:00:00
abstract::The purpose of this study was to train and evaluate teams of standardized (simulated) patients as part of a required course in family medicine for second-year medical students. During three hours of training, six women were trained to play the same person. These standardized teams played four roles during the 12-week ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198708090-00021
更新日期:1987-09-01 00:00:00
abstract:OBJECTIVES:The primary aim of this study was to determine reasons why health care personnel (HCP) in a public health department chose or refused free influenza vaccinations offered at the worksite. METHODS:In an internal review board-approved study, we offered, through a health nurse at the site, self-administered sur...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181eda3d5
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to assess the cardiovascular health status of baby boomers with diabetes mellitus (DM) in comparison to the same-age population with DM 10 years previously. METHODS:The study was conducted in baby boomers with DM using data from the National Health and Nutrition Examination S...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000473
更新日期:2016-06-01 00:00:00
abstract::Valvular heart disease accounts for considerable morbidity and some mortality among patients with end-stage renal disease (ESRD). To determine the prevalence and severity of valvular and perivalvular abnormalities, including valvular thickening, stenosis, calcification, regurgitation, and mitral annular calcification ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199501000-00009
更新日期:1995-01-01 00:00:00
abstract::This report describes a 42-year-old man with Brugada syndrome (BRS) mimicking acute coronary syndrome. Chest pain, near-syncope, and electrocardiographic changes were thought initially to be due to ischemia. Cardiac catheterization was performed. The coronary arteries and left ventricular function were normal. Careful...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000168135.26545.a6
更新日期:2005-08-01 00:00:00
abstract::"Sick building syndrome" (SBS) is one of the more colorful terms describing an increasingly common pattern of symptoms found among workers in modern office buildings. Core symptoms include lethargy, mucous membrane irritation, headache, eye irritation, and dry skin. To prompt a diagnosis of SBS, these otherwise common...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199101000-00015
更新日期:1991-01-01 00:00:00
abstract::Although recent increases in the incidence of syphilis are well known to public health officials, the general medical community is less well informed regarding the dramatic rise in cases. We present trend data from Nashville and Tennessee over the past decade. These statistics emphasize specific factors, such as drug ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199208000-00002
更新日期:1992-08-01 00:00:00
abstract::Transposition of the inferior vena cava, duplication of the inferior vena cava, circumaortic renal collar, and retroaortic renal vein constitute the four most common major venous anomalies occurring in the retroperitoneum. Recent clinical cases are presented to review the embryogenesis, incidence, and clinical importa...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197910000-00012
更新日期:1979-10-01 00:00:00
abstract::Human immunodeficiency virus (HIV) has caused resurgence in tuberculosis (TB) worldwide. HIV-TB coinfected individuals are at increased risk for complications of TB and HIV treatment, such as adverse drug reactions and immune reconstitution syndrome. A 17-year-old male with HIV-TB coinfection, who developed cardiac ta...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181684b92
更新日期:2008-05-01 00:00:00
abstract::From our retrospective review of 30 patients having hepatic resection, we have made the following conclusions: (1) Hepatic resection is an uncommon procedure. (2) The majority of liver injuries require only drainage or suture ligation and drainage. (3) Midline incision, early arterial occlusion, and resectional debrid...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198106000-00006
更新日期:1981-06-01 00:00:00
abstract::In 1954 I described a case of chronic fluoride poisoning from artificially fluoridated water, in which the patient exhibited a multisymptomatic clinical picture without noticeable skeletal changes. Subsequently, others and I have confirmed this "nonskeletal phase" of the disease from fluoride in water and in air (in w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::We have presented a case of tracheobronchitis due to C pseudodiphtheriticum in a patient with COPD who was treated with prednisone and apparently was not otherwise immunocompromised. Chronic lung disease seems to predispose to infection with C pseudodiphtheriticum; it can also occur in the immunocompetent host. This o...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199104000-00026
更新日期:1991-04-01 00:00:00
abstract:OBJECTIVES:Cystic fibrosis (CF) is associated with vitamin D deficiency, which can lead to adverse effects including recurrent pulmonary infections and osteoporosis. We longitudinally investigated calcifediol or 25-hydroxyvitamin D (25(OH)D) levels for our pediatric patients with CF based on the time of year as well as...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000254
更新日期:2015-03-01 00:00:00
abstract::Cough syncope occurs primarily in middle-aged male smokers with chronic obstructive pulmonary disease (COPD). It has also been described in children with asthma. I report the case of a 34-year-old nonsmoker who had syncope due to coughing, and who also related a 1-year history of cough with wheezing. Chest examination...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::A patient with a large paraesophageal hernia had a Nissen fundoplication via laparoscopy. He returned a year later with the transverse colon herniated into the chest. At operation, the hernia ostium was found to be the aortic hiatus. We believe that the original ostium was missed because of the limited exposure of the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199703000-00016
更新日期:1997-03-01 00:00:00
abstract::Massive ovarian edema is a rare tumor-like condition of the ovary characterized by marked enlargement of one or both ovaries due to marked accumulation of edema fluid in the ovarian stroma. This paper reviews the literature on massive ovarian edema and presents a case associated with androgenic manifestations. ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199511000-00015
更新日期:1995-11-01 00:00:00
abstract::To determine the prevalence of frequently occurring neurologic disorders in a biracial population, a survey of households and chronic care institutions was carried out for all residents of Copiah County, Mississippi. Along with a complete census, interviews were held using extensive questions about diagnoses, signs, a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198703000-00016
更新日期:1987-03-01 00:00:00
abstract::A case of brain stem infarction after chiropractic manipulation of the cervical spine is presented. Proposed mechanisms and sites of possible arterial injury are discussed. A diagnosis of vertebral artery occlusion was made using conventional brachial angiography. Digital intravenous angiography, a relatively new and ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198312000-00014
更新日期:1983-12-01 00:00:00
abstract::Primary carcinoma of the trachea is not common. Of 23 cases diagnosed as "carcinoma of the trachea" at our institution since 1949, 21 actually represented secondary involvement from carcinoma of the larynx, lung, or esophagus. The two cases of primary carcinoma of the trachea are presented. Discussed are the relation ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197704000-00020
更新日期:1977-04-01 00:00:00
abstract::A 16-year-old white boy had nephrotic syndrome due to focal segmental glomerulosclerosis six months before the diagnosis of Hodgkin's disease was established. Peritoneal dialysis was necessary for volume control after one month of unsuccessful therapy with high doses of corticosteroids. Nephrosis remitted after two co...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198909000-00034
更新日期:1989-09-01 00:00:00
abstract::From Jan 1, 1978 through Dec 31, 1983, 64 patients with epithelial ovarian tumors, frankly malignant or borderline, were managed at one institution. Nineteen patients (29.7%) were under age 40. The youngest patient was 19 years old. Nulliparity was present in 32% of this group of patients. Of these young patients, 58%...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198801000-00003
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVES:Alloantibody formation secondary to transfusion in patients with sickle cell disease (SCD) is a well-known phenomenon. Pretransfusion testing (eg, "antibody screening") protects patients from receiving incompatible red blood cell transfusions. Because alloantibodies have a tendency to evanesce (ie, become un...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000528
更新日期:2016-09-01 00:00:00
abstract::We prospectively studied preoperative and postoperative grip and pinch strength in 21 patients having 30 consecutive median nerve decompressions for carpal tunnel syndrome. All procedures were done by one surgeon. Each hand operated on served as its own control and was studied by the same therapist preoperatively and ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199209000-00009
更新日期:1992-09-01 00:00:00
abstract::This case study illustrates the relationship between hypothyroidism and bronchial asthma. As seen here, even slow and cautious restoration of the euthyroid state may lead to problems in the management of asthma. Thus routine or aggressive replacement therapy for thyroid hypofunction in the asthmatic population is not ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198403000-00037
更新日期:1984-03-01 00:00:00
abstract::Parkinsonism associated with boxing has attracted recent media attention, yet little has been written about it in the medical literature. This report presents a typical case with a review of the literature. ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198905000-00002
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND:Insulin resistance is characterized by impaired responsiveness to endogenous or exogenous insulin. Loss of responsiveness is associated with a "clustering" of cardiovascular risk factors that includes abdominal obesity, hypertension, dyslipidemia, glucose intolerance, and hyperinsulinemia; this association i...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199901000-00002
更新日期:1999-01-01 00:00:00