Continuous local anesthetic infusion for pain management after outpatient inguinal herniorrhaphy.

Abstract:

BACKGROUND:The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline. METHODS:A prospective, randomized, blinded, placebo-controlled trial was conducted in adults undergoing outpatient inguinal herniorrhaphy. Patients received saline or bupivacaine through a disposable infusion pump for 60 hours postoperatively. Pain outcomes were assessed, as were functional outcomes (activity, return of bowel function) and side effects. RESULTS:On postoperative day 1, patients who received bupivacaine had lower ratings for worst pain than patients who received saline, (5.0 +/- 2.3 vs 6.7 +/- 2.2, P=.002). On day 1, least pain ratings were also lower, and patients ambulated more frequently than those who received placebo. There were no differences between groups from postoperative days 2 to 5. There were no differences between groups in the amount of hydrocodone consumption. CONCLUSIONS:Continuous infusion of local anesthetic after inguinal herniorrhaphy provides modest improvements in pain scores and functional outcomes when compared with placebo. However, these effects are limited to the first postoperative day only. The additional costs associated with this intervention may limit its widespread use in clinical practice.

journal_name

Surgery

journal_title

Surgery

authors

Schurr MJ,Gordon DB,Pellino TA,Scanlon TA

doi

10.1016/j.surg.2004.06.016

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

761-9

issue

4

eissn

0039-6060

issn

1532-7361

pii

S0039606004003903

journal_volume

136

pub_type

临床试验,杂志文章,随机对照试验

相关文献

SURGERY文献大全
  • Urokinase requires NAD(P)H oxidase to transactivate the epidermal growth factor receptor.

    abstract:BACKGROUND:Cell migration is an integral part of the development of intimal hyperplasia, and proteases are pivotal components in the process. Cell migration in response to urokinase is mediated through the aminoterminal fragment (ATF) of the protein. This study examines the role of NAD(P)H oxidase during epidermal grow...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2012.03.004

    authors: Duru EA,Fu Y,Davies MG

    更新日期:2012-11-01 00:00:00

  • Calorie-nitrogen interactions in the parenterally fed primate.

    abstract::To test the hypothesis that nonprotein calorie intake and nitrogen intake are equally important in establishing positive nitrogen balance, weight gain, and serum protein response in the depleted primate treated with total parenteral nutrition (TPN), 10 adult male chair-adapted primates (Macaque fascicularis) were stud...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Dempsey DT,Mullen JL,Crosby LO,Hurwitz S

    更新日期:1988-01-01 00:00:00

  • The myelopoietic effects of a Serratia marcescens-derived biologic response modifier in a mouse model of thermal injury.

    abstract::The proliferative defects observed in phagocytic stem cells after major thermal injuries may be caused by an inadequate production of colony-stimulating factors (CSFs), a family of hemopoietic cytokines necessary for the production and function of granulocytes and monocytes. In this study a biologic response modifier ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Peterson VM,Rundus CH,Reinoehl PJ,Schroeter SR,McCall CA,Bartle EJ

    更新日期:1992-04-01 00:00:00

  • Use of the rapid/shallow breathing index as an indicator of patient work of breathing during pressure support ventilation.

    abstract:BACKGROUND:Measuring patient work of breathing (WOBpt) has been suggested to provide safe, aggressive weaning from mechanical ventilation. We compared WOBpt and pressure-time-product (PTP) to routine weaning parameters [breath rate (f), tidal volume (VT), frequency/tidal volume ratio (f/VT)] at different levels of pres...

    journal_title:Surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0039-6060(97)90081-7

    authors: Johannigman JA,Davis K Jr,Campbell RS,Branson RD,Luchette FA,Hurst JM

    更新日期:1997-10-01 00:00:00

  • Twelve hundred abscesses operatively drained: an antibiotic conundrum?

    abstract:BACKGROUND:The incidence of soft tissue infections from antimicrobial-resistant pathogens is increasing. This study evaluated the epidemiology of operatively drained soft tissue abscesses. METHODS:This retrospective study evaluated 1,200 consecutive patients from 2002 to 2008 who underwent incision and drainage (I&D) ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2009.06.020

    authors: Zimmerman LH,Tyburski JG,Stoffan A,Baylor AE,Dolman HS,Brinks LM,Obiakor H,Wilson RF

    更新日期:2009-10-01 00:00:00

  • Payer status is related to differences in access and outcomes of abdominal aortic aneurysm repair in the United States.

    abstract:BACKGROUND:The hypothesis of this study was that differences exist among patients with private insurance compared with patients with Medicaid or no insurance, regarding access to the timely treatment of abdominal aortic aneurysms (AAAs) and the outcomes of AAA repair. METHODS:The study comprised 5363 patients aged les...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2003.214

    authors: Boxer LK,Dimick JB,Wainess RM,Cowan JA,Henke PK,Stanley JC,Upchurch GR Jr

    更新日期:2003-08-01 00:00:00

  • Long-term surveillance is necessary after operative resection for intraductal papillary mucinous neoplasm of the pancreas.

    abstract:BACKGROUND:There is not enough evidence to establish an appropriate surveillance strategy after operative resection for intraductal papillary mucinous neoplasm. METHODS:This study included 257 consecutive intraductal papillary mucinous neoplasm patients who underwent operative resection between July 1999 and March 201...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.04.007

    authors: Hirono S,Kawai M,Okada K,Miyazawa M,Shimizu A,Kitahata Y,Ueno M,Yanagisawa A,Yamaue H

    更新日期:2016-08-01 00:00:00

  • Homotransplant renal artery stenosis.

    abstract::Transplant renal artery stenosis occurred in 12 of 101 consecutive kidney transplants. Stenoses were all located in the renal artery distal to the anastomosis. Two separate forms of stenosis are recognized: angulation and segmental. All transplant patients with severe diastolic hypertension, refractory to medical mana...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Doyle TJ,McGregor WR,Fox PS,Maddison FE,Rodgers RE,Kauffman HM

    更新日期:1975-01-01 00:00:00

  • Role for adrenal venous sampling in primary aldosteronism.

    abstract:BACKGROUND:The aim of this study was to determine the effect of adrenal venous sampling (AVS) on the management of patients with primary aldosteronism. METHODS:From September 1990 through October 2003, 203 patients with primary aldosteronism (mean age, 53 years; range, 17-80; 163 men) were selected prospectively for A...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2004.06.051

    authors: Young WF,Stanson AW,Thompson GB,Grant CS,Farley DR,van Heerden JA

    更新日期:2004-12-01 00:00:00

  • The interaction of retrovirus and chemical carcinogen in experimental colon carcinogenesis.

    abstract::The isolation and characterization of oncogenes from human colon cancer and the recognition of their homology with the ras gene of the Harvey and Kirsten strain of murine sarcoma virus (MSV) led us to investigate the effect of exogenous MSV on 1,2 dimethylhydrazine (DMH)-induced colon carcinoma in rats. DMH, 20 mg bas...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Nelson RL,Wilson W,Samelson SL,Khoobyarian N

    更新日期:1987-02-01 00:00:00

  • Reducing postoperative pain, narcotics, and length of hospitalization.

    abstract::Bupivacaine wound infiltration together with efficient esophagogastric decompression and immediate elemental feeding in 43 consecutive, well-instructed patients who had undergone cholecystectomy reduced their postoperative analgesia requirements to an average of 17 (+/- 46, SD) mg of meperidine during the initial 24 h...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Moss G,Regal ME,Lichtig L

    更新日期:1986-02-01 00:00:00

  • Chronic extrinsic denervation after small bowel transplantation in rat jejunum: Effects and adaptation in nitrergic and non-nitrergic neuromuscular inhibitory mechanisms.

    abstract:BACKGROUND:Extrinsic denervation of the transplanted small bowel could play a substantial role in motor dysfunction of the transplanted gut. We attempted to determine the effect of chronic extrinsic denervation on intestinal contractility. METHODS:Jejunal longitudinal muscle strips were obtained from rats 1 week and 8...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2001.112070

    authors: Balsiger BM,Ohtani N,Anding WJ,Duenes JA,Sarr MG

    更新日期:2001-04-01 00:00:00

  • The effect on protein and amino acid metabolism of an intravenous nutrition regimen providing seventy percent of nonprotein calories as lipid.

    abstract:BACKGROUND:The purpose of this study was to determine which peripheral intravenous nutrition (IVN) regimen, one containing 70% nonprotein calories as lipid IVN or one containing all nonprotein calories as glucose IVN, was most effective at reversing some effects of surgery on protein metabolism. METHODS:Twenty patient...

    journal_title:Surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Smith RC,Mackie W,Kohlhardt SR,Kee AJ

    更新日期:1992-01-01 00:00:00

  • Peptide YY immunoneutralization inhibits meal-induced absorption in vivo.

    abstract:BACKGROUND:Plasma peptide YY (PYY) levels rise after a meal and have recently been shown to increase small bowel-absorption. The purpose of this study was to determine whether immunoneutralization of PYY would block postprandial absorption in vivo. METHODS:Exteriorized, neurovascularly intact jejunal and ileal segment...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Bilchik AJ,Hines OJ,Ashley SW,Adrian TE,Walsh J,Wong H,Liu CD,Zinner MJ,McFadden DW

    更新日期:1994-12-01 00:00:00

  • Reflections on a leadership development program: Impacts on culture in a surgical environment.

    abstract:BACKGROUND:Although a growing body of literature has focused on the impacts leadership development programs have had on the individual surgeon, little effort has been focused on understanding the impacts these programs have had on surgical culture. The purpose of this study was to explore the impacts of implementing a ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.05.015

    authors: Vitous CA,Shubeck S,Kanters A,Mulholland M,Dimick JB

    更新日期:2019-11-01 00:00:00

  • Quantitative ultrasonic blood flow measurement in Dacron grafts.

    abstract::A quantitative directional Doppler system was used to determine blood flow in 8 mm. aortoaortic Dacron grafts in dogs. The Doppler was calibrated with frequency standards and the output was integrated for one minute intervals. With the probe held at an angle of 60 degrees to the flow axis, the average frequency of the...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: LoGerfo FW,Corson JD

    更新日期:1976-05-01 00:00:00

  • Big data: More than big data sets.

    abstract::The term big data has been popularized over the past decade and is often used to refer to data sets that are too large or complex to be analyzed by traditional means. Although the term has been utilized for some time in business and engineering, the concept of big data is relatively new to medicine. The reception from...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2018.06.022

    authors: Cobb AN,Benjamin AJ,Huang ES,Kuo PC

    更新日期:2018-10-01 00:00:00

  • Tertiary hyperparathyroidism: is less than a subtotal resection ever appropriate? A study of long-term outcomes.

    abstract:BACKGROUND:Our aim was to examine the outcomes of patients with tertiary hyperparathyroidism (3-HPT) who had limited resection of 1 or 2 parathyroids. METHODS:We reviewed 140 patients with 3-HPT who underwent parathyroidectomy (PTX) at a single institution. Patients were analyzed according to their operation-limited P...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2009.09.026

    authors: Pitt SC,Panneerselvan R,Chen H,Sippel RS

    更新日期:2009-12-01 00:00:00

  • Irresectable hepatoma treated by intrahepatic iodized oil doxorubicin hydrochloride: initial results.

    abstract::In this study we describe the investigation and treatment of 14 patients with primary hepatocellular carcinoma. Patients were treated with intra-arterial infusion of iodized oil and doxorubicin hydrochloride. Five of these patients were alive after 1 year. Twelve patients showed a fall in alpha-fetoprotein, and in sev...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Kirk S,Blumgart R,Craig B,Rosen A,Terblanche J,Spence RA

    更新日期:1991-06-01 00:00:00

  • Anastomotic leak predicts diminished long-term survival after resection for gastric and esophageal cancer.

    abstract:BACKGROUND:Previous studies have reported on the association between perioperative morbidity and diminished oncologic outcomes in patients undergoing resection for colorectal or pancreatic cancer. However, the effect of anastomotic leak (AL) on the survival of patients with gastric or esophageal cancer remains unclear....

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.02.020

    authors: Andreou A,Biebl M,Dadras M,Struecker B,Sauer IM,Thuss-Patience PC,Chopra S,Fikatas P,Bahra M,Seehofer D,Pratschke J,Schmidt SC

    更新日期:2016-07-01 00:00:00

  • Bacteremic infectability of vascular grafts: the influence of pseudointimal integrity and duration of graft function.

    abstract::This report describes an experimental study in which dogs with prosthetic graft replacement of the infrarenal abdominal aorta were challenged at progressive time intervals following graft placement with a single intravenous infusion of Staphylococcus aureus in order to determine the duration of susceptibility to graft...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Malone JM,Moore WS,Campagna G,Bean B

    更新日期:1975-08-01 00:00:00

  • Prognostic significance of tumor DNA content in carcinoma of the hepatic duct confluence.

    abstract:BACKGROUND:In an attempt to identify prognostic factors in carcinoma of the hepatic duct confluence, the value of tumor DNA content was studied in 58 patients with this type of malignancy. METHODS:Of 58 patients (ages 26 to 74 years) surgically treated for carcinoma of the hepatic duct confluence, tumor DNA content wa...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Sato Y,van Gulik TM,Bosma A,Lygidakis NJ,Koyama K,van der Heyde MN

    更新日期:1994-04-01 00:00:00

  • Use of a somatostatin analog (SMS 201-995) in the glucagonoma syndrome.

    abstract::A long-acting somatostatin analog, SMS 201-995, is now available to treat the hormonal manifestations of islet cell tumors. We report its use in a patient with a metastatic glucagonoma refractory to conventional therapy. This patient, who was severely disabled by the rash of necrolytic migratory erythema and brittle d...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Altimari AF,Bhoopalam N,O'Dorsio T,Lange CL,Sandberg L,Prinz RA

    更新日期:1986-12-01 00:00:00

  • Amino acid metabolism in patients with severe burns.

    abstract::In this study we set out to determine, if relative to net catabolism of skeletal muscle protein as measured by phenylalanine release, the transamination of branched-chain amino acids (valine, isoleucine, and leucine) was greater in nonseptic burn patients than in controls. Arterial and femoral venous amino acid concen...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Snelling CF,Woolf LI,Groves AC,Moore JP,Duff JH

    更新日期:1982-04-01 00:00:00

  • Routine parathyroid autotransplantation during thyroidectomy.

    abstract:BACKGROUND:Parathyroid autotransplantation (PTHAT) during thyroidectomy has been shown to reduce the incidence of permanent hypoparathyroidism. Although selective PTHAT is most commonly adopted, the value of routine PTHAT has not been well documented. METHODS:From January, 1998 to March, 1999, an operative strategy in...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2001.111125

    authors: Lo CY,Lam KY

    更新日期:2001-03-01 00:00:00

  • Planned extra-anatomic cerebral revascularization for carotid artery ligation.

    abstract::Cerebral revascularization, using extra-anatomic bypass grafts of autologous saphenous vein, was performed in three patients to prevent or to compensate for ischemic effects of emergency ligation of a carotid artery. These ligations were required after spontaneous disruption of common carotid arteries in patients with...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Bole PV,Babu S,Clauss RH

    更新日期:1978-04-01 00:00:00

  • Phenotype mapping of the multiple endocrine neoplasia type II syndrome.

    abstract::The multiple endocrine neoplasia (MEN) IIb syndrome has been differentiated from MEN IIa by the presence of various phenotypic characteristics such as mucosal neuromas, marfanoid habitus, congenital skeletal anomalies, and prominent corneal nerves, as well as the lack of parathyroid involvement. Analysis of a kindred ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Talpos GB,Jackson CE,Yott JB,Van Dyke DL

    更新日期:1983-10-01 00:00:00

  • Hyperparathyroidism and gastroenteropancreatic hormone levels.

    abstract::The diagnosis of multiple endocrine neoplasia (MEN) in patients with presumed hyperparathyroidism has important ramifications for patient management especially since as many as 20% of patients with hyperparathyroidism may have associated MEN. Gut hormone levels were measured before and after surgery in 28 patients who...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Strodel WE,Vinik AI,Eckhauser FE,Thompson NW

    更新日期:1985-12-01 00:00:00

  • Evaluation and management of thoracopancreatic fistula.

    abstract:BACKGROUND:Thoracopancreatic fistula is a rare clinical entity but a serious complication of inflammatory pancreatic diseases, caused by a disruption of the pancreatic ductal system. Its diagnosis is frequently misleading, however, and thus is often delayed. METHODS:Seven patients with thoracopancreatic fistula who pr...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2006.02.020

    authors: Tajima Y,Tsutsumi R,Kuroki T,Mishima T,Adachi T,Kitasato A,Kanematsu T

    更新日期:2006-11-01 00:00:00

  • Effect of the Bethesda system for reporting thyroid cytopathology on thyroidectomy rates and malignancy risk in cytologically indeterminate lesions.

    abstract:BACKGROUND:Cytologically indeterminate thyroid nodules represent a diagnostic and therapeutic challenge. In 2007, the National Cancer Institute recommended The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) as a means of improving the accuracy of thyroid cytopathology. Our objective was to determine the e...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2010.09.017

    authors: Rabaglia JL,Kabbani W,Wallace L,Holt S,Watumull L,Pruitt J,Snyder WH,Nwariaku FE

    更新日期:2010-12-01 00:00:00