Abstract:
OBJECTIVE:To assess the association of the A1166C polymorphism of the angiotensin II type-1 receptor (AT1R) gene with acute myocardial infarction and also with the severity of coronary artery disease. METHODS:A prospective, cross-sectional study was carried out with 110 patients with acute myocardial infarction, who, on coronary angiography, had significant lesions (> 50%) assessed according to 3 criteria of severity: number of vessels affected, morphology of the atherosclerotic plaque, and coronary risk score. The control group comprised 104 individuals with no coronary lesions. The A1166C polymorphism of AT1R gene was determined by polymerase chain reaction in the DNA of leukocytes in peripheral blood. The classic coronary risk factors were analyzed in all individuals. RESULTS:When stratifying the genotypes in regard to risk factors, only smoking predominated in the AC heterozygous patients (P = 0.02). The genotypic frequency in the infarcted patients was as follows: AA = 54.5%; AC = 35.5%; and CC = 10%, which was similar and nonsignificant in regard to that in the control group (P = 0.83). No risk increase occurred for acute myocardial infarction when comparing the genotypes as follows: CC vs AA (OR = 1.35; 95% CI = 0.50 - 3.59); AC vs AA (OR = 1.03; 95% CI = 0.58 - 1.84); and AA+AC vs AA (OR = 1.33; 95% CI = 0.51 - 3.45). None of the severity criteria showed a significant correlation with the genotypes. CONCLUSION:According to our results, no correlation exists between the A1166C polymorphism of the angiotensin II type-1 receptor (AT1R) gene and acute myocardial infarction or the severity of coronary artery disease.
journal_name
Arq Bras Cardioljournal_title
Arquivos brasileiros de cardiologiaauthors
Araújo MA,Menezes BS,Lourenço C,Cordeiro ER,Gatti RR,Goulart LRdoi
/S0066-782X2004001700007subject
Has Abstractpub_date
2004-11-01 00:00:00pages
409-13; 404-8issue
5eissn
0066-782Xissn
1678-4170pii
S0066-782X2004001700007journal_volume
83pub_type
杂志文章abstract:BACKGROUND:Several studies have demonstrated clinical benefits of fish consumption for the cardiovascular system. These effects are attributed to the increased amounts of polyunsaturated fatty acids in these foods. However, the concentrations of fatty acids may vary according to region. OBJECTIVE:The goal of this stud...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20140176
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between cardiovascular risk factors and the anthropometric values--body mass index (BMI) and waist circumference (WC). METHODS:It was studied 231 employees of Federal University of Viçosa, Brazil, 54.1% of them were men (21-76 years old). Glycemia, total cholesterol, LDL, HDL, tri...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2006001900008
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Studies have shown that pre/postnatal undernutrition leads to higher risk of non communicable diseases such as diabetes, hypertension and obesity in adulthood. OBJECTIVE:To determine whether overweight adolescents with mild stunting [height-for-age Z scores (HAZ) in the range <-1 to ≥ -2] have higher blood ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2011005000115
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Hypertension is related to increased body fat, which can be evaluated by anthropometric indicators. OBJECTIVE:To determine the predictive power of anthropometric indicators and establish their cutoff points as discriminators of high blood pressure. METHODS:Cross-sectional study with a sample of 660 adolesc...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2010005000153
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:When the Japanese immigrated to the Americas, they were subjected to Westernization, with a great change in lifestyle, specially in dietary habits, and this may explain the increase in the incidence of diabetes mellitus (DM), metabolic syndrome (MS) and cardiovascular disease among them. OBJECTIVE:To study ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2009000500008
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:To evaluate clinical findings and etiology of bacterial infections diagnosed in 100 consecutive heart transplantations. METHODS:One hundred consecutive heart transplant patients were studied. Follow-up after heart transplantation varied from 3 to 90 (mean 25.38 +/- SD 25.97) months. Etiology of bacterial infec...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Birth weight (BW) is a medium- and long-term risk determinant of cardiovascular risk factors. OBJECTIVE:To assess the association between BW and cardiovascular risk factors in adolescents of the city of Salvador, Bahia state. METHODS:Cross-sectional study with comparison of BW groups. Sample comprising 250...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20130114
更新日期:2013-07-01 00:00:00
abstract::The challenges that the COVID-19 pandemic cretead to the healthcare system have made it necessary to adapt routines and services, with the objectives of controlling the spread of the virus and preserving health. Safe and correct management of patients in risks groups, such as elderly patients, patients with cardiovasc...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.36660/abc.20200405
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:The new European Society of Cardiology guidelines for hypertrophic cardiomyopathy (HCM) define the estimation of sudden cardiac death (SCD) risk as an integral part of clinical management. An implantable cardioverter defibrillator (ICD) is recommended (class IIa) when the risk is ≥ 6%. OBJECTIVES:To compare...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20180099
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The occurrence of minute-ventilation oscillations during exercise, named periodic breathing, exhibits important prognostic information in heart failure. Considering that exercise training could influence the fluctuation of ventilatory components during exercise, we hypothesized that ventilatory variability d...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20170104
更新日期:2017-09-01 00:00:00
abstract::Cardiovascular diseases (CVD) are a major cause of death in developed countries as well as in developing countries. In general, the clinical manifestations of CVD, such as myocardial infarction, stroke and peripheral vascular disease, are caused by an atherosclerotic process with onset as from the middle age. However,...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,评审
doi:10.1590/s0066-782x2008000400012
更新日期:2008-04-01 00:00:00
abstract::Ebstein's anomaly, although the most common malformation of the tricuspid valve, is a rare disease. Its association with other syndromes and extracardiac anomalies is very rare and has been reported in only a few cases. A case of prenatal diagnosis of Ebstein's anomaly in a patient with Down's syndrome is reported. ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2004000400011
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Knowledge about the disease itself can be important for self-care in patients with several problems and comprehends information about the diagnosis up to the most important clinical implications. OBJECTIVE:To identify the level of knowledge of children and adolescents with congenital heart disease (CHD) abo...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.36660/abc.20180417
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:To study the factors associated with the risk of in-hospital death in acute myocardial infarction in the Brazilian public health system in Rio de Janeiro, Brazil. METHODS:Sectional study of a sample with 391 randomly drawn medical records of the hospitalizations due to acute myocardial infarction recorded in...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2003000600003
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Posterior subcapsular cataract is a tissue reaction commonly found among professionals exposed to ionizing radiation. OBJECTIVE:To assess the prevalence of cataract in professionals working in hemodynamics in Brazil. METHODS:Professionals exposed to ionizing radiation (group 1, G1) underwent slit lamp exam...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20190028
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Although the effects of salt intake reduction on casual blood pressure have been extensively studied in hypertensive individuals, data on reductions of added salt on arterial stiffness in both normotensive and prehypertensive subjects are scarce. OBJECTIVE:To evaluate the effects of progressive reduction in...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 临床试验,杂志文章
doi:10.36660/abc.20180426
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Abdominal circumference (WC) is the measure that correlates most closely with the risk factors and death from cardiovascular disease. However, the impact of obesity on the prognosis of patients with cardiovascular disease remains controversial and requires further clarification. OBJECTIVE:To evaluate WA as ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2011005000040
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To study the clinical pattern of subaortic stenosis associated with perimembranous ventricular septal defect. METHODS:From January 1979 to June 2000, 36 children with perimembranous ventricular septal defect and fixed subaortic stenosis were followed-up regarding anatomic characteristics, evolvement, and cli...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2005000200002
更新日期:2005-02-01 00:00:00
abstract::Blood pressure (BP)-lowering therapy improves left ventricular (LV) parameters of hypertensive target-organ damage in stage II hypertension, but whether there is a drug-class difference in echocardiographic parameters in stage I hypertension patients is less often studied. In the PREVER treatment study, where individu...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.5935/abc.20180249
更新日期:2019-01-01 00:00:00
abstract::[This corrects the article doi: 10.5935/abc.20120401]. ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20190091
更新日期:2019-06-06 00:00:00
abstract:BACKGROUND:Percutaneous intervention in patients with bioprosthetic mitral valve dysfunction is an alternative to conventional surgical treatment. OBJECTIVES:To report the first Brazilian experience with transseptal transcatheter bioprosthetic mitral valve-in-valve implantation (transseptal-TMVIV). METHODS:Patients w...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,多中心研究
doi:10.36660/abc.20190252
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of swimming on pulmonary water content in animals with heart failure (HF) after myocardial infarction (MI).
METHODS:After coronary occlusion, MI size 20%
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2006001400008
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Cardiovascular diseases (CVD) are the leading causes of death in our population. There was a progressive decrease in mortality due to CVD up to 2005. OBJECTIVE:To update the trends in mortality from cardiovascular diseases in Brazil and in the metropolitan region of São Paulo (MRSP) from 1990 to 2009. METH...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2012005000061
更新日期:2012-08-01 00:00:00
abstract::We presented two cases of falsely elevated CK-MB due to the presence of a type 2 macro CK, showed by isoenzymes electrophoresis. The association of this CK-MB falsely elevated with some digestive diseases are frequent. Quantification of CK isoenzymes by electrophoresis could be indicated in those cases in which the cl...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:PURPOSE:To evaluate epidemiological, clinical and therapeutic aspects of elderly patients with cardiovascular disease in Brazil. METHODS:Elderly patients with cardiovascular disease treated in 36 centers of cardiology and geriatrics were investigated through a questionnaire applied to those who had an appointment duri...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,多中心研究
doi:10.1590/s0066-782x1997001100007
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:To analyze the parameters of the time domain P-wave signal-averaged electrocardiogram (P-SAECG) and compare them with the P-wave duration on the conventional electrocardiogram (P on ECG) as well as the left atrium diameter (LAD) and left ventricular ejection fraction (EF) obtained on the echocardiogram in ord...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2006001800003
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Evidences suggest that paraoxonase 1 (PON1) confers important antioxidant and anti-inflammatory properties when associated with high-density lipoprotein (HDL). OBJECTIVE:To investigate the relationships between p.Q192R SNP of PON1, biochemical parameters and carotid atherosclerosis in an asymptomatic, normo...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20150053
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To determine the diagnostic accuracy of echocardiography for indicating surgery without catheterization in patients with congenital heart disease through a prospective analysis and comparison of the echocardiographic diagnosis with the intraoperative findings, or invasive study, or both. METHODS:From Februar...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2005000500006
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Despite the high prevalence and clinical importance of atrial fibrillation (AF), there is no Brazilian study describing the clinical profile of patients with AF and the most used treatment strategy (rhythm control vs. rate control). OBJECTIVE:Assess the most common treatment on AF in an outpatient specializ...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2012005000020
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Although team-based care is recommended for patients with hypertension, results of this intervention in a real-world setting are missing in the literature. OBJECTIVE:To report the results of a real-world long-term team-based care for hypertensive patients we conducted this study. METHODS:Data of hypertensi...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.36660/abc.20180384
更新日期:2020-08-28 00:00:00