Nortriptyline-induced fulminant hepatic failure.

Abstract:

:We describe, to our knowledge, the first reported case of nortriptyline-induced fulminant hepatic failure. This tricyclic antidepressant drug was taken by a postmenopausal woman for 64 days before her presentation. The absence of fever, rash, or marked eosinophilia, the predominant zone 3 necrosis with bridging, and the latent period favor a metabolic idiosyncratic reaction. The fatal outcome underscores the importance of recognizing the association and discontinuing the offending agent.

journal_name

J Clin Gastroenterol

authors

Berkelhammer C,Kher N,Berry C,Largosa A

doi

10.1097/00004836-199501000-00014

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

54-6

issue

1

eissn

0192-0790

issn

1539-2031

journal_volume

20

pub_type

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