Administrative Database Research Overestimates the Rate of Interval Colon Cancer.

Abstract:

GOALS:Our study reexamines the prevalence of interval colorectal cancer (I-CRC) by manually reviewing CRC cases at a single institution. BACKGROUND:In 2% to 8% of patients with CRC, diagnosis occurs during the interval 6 to 36 months after a cancer-free colonoscopy. Rates are often determined by linking the date of colonoscopy with cancer registry information. STUDY:We examined all colonoscopies from 1993 to 2011. These examinations were linked with Pennsylvania Cancer Registry data. Matched charts were manually reviewed. We determined whether the CRC was "prevalent" or, for patients with a previous colonoscopy, whether they were interval or noninterval based on time from last colonoscopy. For interval cases, we identified "administrative errors" that could falsely increase the number of reported I-CRC. RESULTS:Over the study period, 43,661 colonoscopies were performed, with 1147 (2.6%) positive for CRC after excluding cases (n=52) in which patients had IBD, previous surgery, or nonadenocarcinoma malignancy. Prevalent CRCs totaled 1062 (92.6%). Noninterval CRCs (diagnosed over 36 mo from index colonoscopy) were present in 40 (3.5%). There remained 45 (3.9%) potential I-CRC cases. However, after manual review, 21 cases were found to be administrative errors. Therefore, the accurate proportion of colonoscopies that found an I-CRC was 2.1% (95% confidence interval, 1.5%-3.2%). CONCLUSIONS:The prevalence of I-CRC at our institution before adjustment was comparable with previously reported rates. This proportion was 47% lower after adjusting for administrative errors placing our figure at the lower end of reported I-CRC incidence. Reported rates of I-CRC may be falsely elevated due to errors unique to merging administrative databases.

journal_name

J Clin Gastroenterol

authors

Gotfried J,Bernstein M,Ehrlich AC,Friedenberg FK

doi

10.1097/MCG.0000000000000183

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

483-90

issue

6

eissn

0192-0790

issn

1539-2031

journal_volume

49

pub_type

杂志文章
  • Ursodeoxycholic acid for adjuvant therapy with extracorporeal shock wave lithotripsy of gallstones.

    abstract::Extracorporeal shock wave lithotripsy (ESWL) of gallstones is a new and experimental treatment. Recent data seem to indicate that the use of ursodeoxycholic acid (UDCA) after ESWL may optimize the results of the shock wave treatment. Most of the published data on the clinical use of such therapy emanate from two studi...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,评审

    doi:

    authors: Fromm H

    更新日期:1988-01-01 00:00:00

  • Plasma intestinal fatty acid-binding protein levels correlate with morphologic epithelial intestinal damage in a human translational ischemia-reperfusion model.

    abstract:BACKGROUND AND AIM:Intestinal fatty acid-binding protein (I-FABP) is a useful marker in the detection of intestinal ischemia. However, more insight into the test characteristics of I-FABP release is needed. This study aimed to investigate the relationship between plasma I-FABP levels and the severity of ischemic mucosa...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e3182a87e3e

    authors: Schellekens DH,Grootjans J,Dello SA,van Bijnen AA,van Dam RM,Dejong CH,Derikx JP,Buurman WA

    更新日期:2014-03-01 00:00:00

  • Barrett's esophagus and adenocarcinoma. The need for a consensus conference.

    abstract::The fear of cancer has evoked calls for intensive surveillance programs in Barrett's esophagus. Two evolving issues are fueling this fire: (a) the rising risk of adenocarcinoma of the esophagus over the past 20 years and (b) the coincidental increase in the recognized prevalence of Barrett's esophagus in the general p...

    journal_title:Journal of clinical gastroenterology

    pub_type: 社论

    doi:10.1097/00004836-199609000-00002

    authors: Richter JE,Falk GW

    更新日期:1996-09-01 00:00:00

  • Management of Chronic Hepatitis B in Pregnancy.

    abstract::Chronic hepatitis B virus (HBV) infection due to mother-to-child transmission during the perinatal period remains an important global health problem. Despite standard passive-active immunoprophylaxis with hepatitis B immunoglobulin and hepatitis B vaccine in neonates, up to 8.5% of newborns still acquire HBV infection...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0000000000000908

    authors: Li J,Chang MS,Tran TT,Nguyen MH

    更新日期:2017-10-01 00:00:00

  • The Interaction Between Celiac Disease and Intestinal Microbiota.

    abstract::Celiac disease (CD) is the most common autoimmune enteropathy, triggered by a deregulated immune response to gliadin. It has been hypothesized that human intestinal microbiota may interfere with the pathogenesis of the disease and in the clinical course of CD. In the present review, we analyzed the microbiota alterati...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0000000000000682

    authors: Losurdo G,Principi M,Iannone A,Ierardi E,Di Leo A

    更新日期:2016-11-01 00:00:00

  • Comparison of hepatic venous pressure gradient and two models of end-stage liver disease for predicting the survival in patients with decompensated liver cirrhosis.

    abstract:GOALS:We evaluated the efficacy of initial and follow-up hepatic venous pressure gradient (HVPG), models of end-stage liver disease (MELD), and MELD-Na for predicting the survival of patients with decompensated liver cirrhosis (LC). BACKGROUND:MELD with/without Na score and HVPG have been important predictors of morta...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e31825f2622

    authors: Suk KT,Kim CH,Park SH,Sung HT,Choi JY,Han KH,Hong SH,Kim DY,Yoon JH,Kim YS,Baik GH,Kim JB,Kim DJ

    更新日期:2012-11-01 00:00:00

  • Multiple esophageal webs: treatment and follow-up of seven patients.

    abstract::We have treated seven patients with multiple esophageal webs without a predisposing disorder. The patients ranged in age from 34 to 61 years and had suffered from dysphagia for 4 to 26 years. None had skin disease, a history of ingestion of a potentially caustic substance, or evidence of gastroesophageal reflux diseas...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199706000-00003

    authors: Longstreth GF,Sitzer ME

    更新日期:1997-06-01 00:00:00

  • Effects of lansoprazole on ethanol-induced injury and PG synthetic activity in rat gastric mucosa.

    abstract::Lansoprazole, a proton pump inhibitor, has been reported to inhibit ethanol-induced injury in rats. However, the mechanism of the protective effect is not known. This study was carried out to investigate the role of prostaglandin (PG) in the protective effect of lansoprazole. Male Wistar rats were given either 30 mg/k...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199506002-00003

    authors: Fukuda T,Arakawa T,Shimizu Y,Ohtani K,Higuchi K,Kobayashi K

    更新日期:1995-01-01 00:00:00

  • Inhibition of inducible nitric oxide synthase delays gastric ulcer healing in the rat.

    abstract::We sought to clarify the role of nitric oxide (NO) generated from inducible NO synthase (iNOS) during healing of rat gastric ulcers. After gastric ulcers were induced by acetic acid, rats were treated with vehicle, N(G)-nitro-L-arginine methyl ester (L-NAME), aminoguanidine (AG), and dexamethasone (Dex) by gastric int...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199800001-00011

    authors: Akiba Y,Nakamura M,Mori M,Suzuki H,Oda M,Kimura H,Miura S,Tsuchiya M,Ishii H

    更新日期:1998-01-01 00:00:00

  • Long-term prognosis of the jejunal involvement of Crohn's disease.

    abstract:GOALS:We investigated the prognosis of Crohn's disease (CD) in Korean patients with jejunal involvement. BACKGROUND:Although jejunal involvement is considered a poor prognostic factor of CD in whites, it has never been validated in Asian populations. METHODS:We retrospectively reviewed the medical records of 1403 Kor...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e3182705f9e

    authors: Park SK,Yang SK,Park SH,Park SH,Kim JW,Yang DH,Jung KW,Kim KJ,Ye BD,Byeon JS,Myung SJ,Yu CS,Kim JH

    更新日期:2013-05-01 00:00:00

  • Cannabinoids: A Guide for Use in the World of Gastrointestinal Disease.

    abstract::Cannabinoids have been known as the primary component of cannabis for decades, but the characterization of the endocannabinoid system (ECS) in the 1990s opened the doors for cannabis' use in modern medicine. The 2 main receptors of this system, cannabinoid receptors 1 and 2, are found on cells of various tissues, with...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000001287

    authors: Unal E,Anderson B,Helber A,Marks JH

    更新日期:2020-10-01 00:00:00

  • Pneumatic dilation for the treatment of achalasia in untreated patients and patients with failed Heller myotomy.

    abstract:BACKGROUND:Laparoscopic Heller myotomy (HM) has become an increasingly preferred modality to treat achalasia. However, the treatment course after a failed myotomy is controversial with fears that pneumatic dilation (PD) has high perforation risk. GOAL:To compare success and safety of graded PD with Rigiflex balloons i...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200411000-00004

    authors: Guardino JM,Vela MF,Connor JT,Richter JE

    更新日期:2004-11-01 00:00:00

  • Serum lipase levels in chronic alcoholics.

    abstract::Using an elevated serum amylase level to diagnose acute pancreatitis in an alcoholic patient with abdominal pain may not be appropriate, because hyperamylesemia is common in asymptomatic alcoholics without acute pancreatitis. To determine whether serum lipase also suffers from the same drawback, we undertook a prospec...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199108000-00009

    authors: Gumaste VV,Sereny G,Dave P,Bhardwaj A,Gumaste S

    更新日期:1991-08-01 00:00:00

  • A case of cyclosporine-sensitive, steroid-resistant, autoimmune chronic active hepatitis.

    abstract::Few alternative treatments are available for those patients with autoimmune chronic active hepatitis who fail to respond to the conventional treatment of corticosteroids. Such patients have a poor prognosis and frequently require liver transplantation. We report a patient with autoimmune hepatitis who failed treatment...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199312000-00012

    authors: Person JL,McHutchison JG,Fong TL,Redeker AG

    更新日期:1993-12-01 00:00:00

  • The Cronkhite-Canada syndrome with focus on immunity and infection. Report of a case.

    abstract::A 64-year-old man developed diffuse gastrointestinal polyposis, protein-losing enteropathy, skin pigmentation, hair loss, and unique nail changes. He also exhibited pulmonary tuberculosis and impaired immunity with skin anergy, poor lymphocyte mitogens stimulation test, and low serum immunoglobulin. We discuss the rel...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198710000-00018

    authors: Lin HJ,Tsai YT,Lee SD,Lai KH,Ng WW,Tam TN,Lin HC,Liou LB,Tsay SH

    更新日期:1987-10-01 00:00:00

  • Rapid development of pancreatitis following reuse of 6-mercaptopurine.

    abstract::A patient with Crohn's disease developed acute pancreatitis 4 h after retaking one 50 mg dose of orally administered 6-mercaptopurine (6-MP). All seven previously reported patients who were rechallenged with 50 mg or more of 6-MP developed pancreatitis within 48 h. These findings suggest that 6-MP can produce pancreat...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198912000-00017

    authors: Cappell MS,Das KM

    更新日期:1989-12-01 00:00:00

  • Biliary tract obstruction secondary to mycosis fungoides: a case report.

    abstract::Mycosis fungoides is a cutaneous T-cell lymphoma that can disseminate to multiple organs. We report a patient who presented with obstructive jaundice caused by isolated involvement of the extrahepatic biliary tree by mycosis fungoides. Initially, endoscopic examinations and biopsies of the biliary tree and liver faile...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199901000-00015

    authors: Madsen JA,Tallini G,Glusac EJ,Salem RR,Braverman I,Robert ME

    更新日期:1999-01-01 00:00:00

  • Alpha-fetoprotein-producing clear cell carcinoma of the extrahepatic bile ducts.

    abstract::A 79-year-old woman visiting our hospital with chief complaints of epigastric pain and jaundice was emergently admitted. Her alpha-fetoprotein (AFP) level was as high as 2265 ng/mL at admission. Her abdominal computed tomography scan revealed dilation of the intrahepatic bile duct and a tumorlike lesion protruding int...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200607000-00016

    authors: Miyazawa M,Torii T,Toshimitsu Y,Kamizasa N,Suzuki T,Shinozuka N,Ishizawa K,Koyama I

    更新日期:2006-07-01 00:00:00

  • Development of Image-enhanced Endoscopy of the Gastrointestinal Tract: A Review of History and Current Evidences.

    abstract::Endoscopy imaging of the gastrointestinal (GI) tract has evolved tremendously over the last few decades. Key milestones in the development of endoscopy imaging include the use of various dyes for chromoendoscopy, the application of optical magnification in endoscopy, the introduction of high-definition image capturing...

    journal_title:Journal of clinical gastroenterology

    pub_type: 历史文章,杂志文章

    doi:10.1097/MCG.0000000000000960

    authors: Ho SH,Uedo N,Aso A,Shimizu S,Saito Y,Yao K,Goh KL

    更新日期:2018-04-01 00:00:00

  • Role of Gut Microbiota in Liver Disease.

    abstract::Many lines of research have established a relationship between the gut microbiome and patients with liver disease. For example, patients with cirrhosis have increased bacteremia, increased blood levels of lipopolysaccharide, and increased intestinal permeability. Patients with cirrhosis have bacterial overgrowth in th...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000391

    authors: Brenner DA,Paik YH,Schnabl B

    更新日期:2015-11-01 00:00:00

  • Biofeedback improvement of lower esophageal sphincter pressures and reflux symptoms.

    abstract::During a course of 10 biofeedback sessions in a single subject, the lower esophageal sphincter pressure measured with an open-tipped perfused catheter assembly showed significant and progressive increase with each session, until it reached normal levels. There was also a decrease in symptomatic reflux episodes, from t...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198306000-00008

    authors: Gordon A,Gordon E,Berelowitz M,Bremner CH,Bremner CG

    更新日期:1983-06-01 00:00:00

  • Postpartum Laboratory Follow-up in Women With Hepatitis B in Massachusetts From 2007 to 2012.

    abstract:GOALS:To determine postpartum hepatitis B virus (HBV) laboratory testing rates and identify factors associated with a lack of follow-up testing in Massachusetts. BACKGROUND:Screening for HBV infection in pregnant women is standard of care. Guidelines recommend that patients with chronic HBV have ongoing care and labor...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000530

    authors: Chang MS,Barton K,Crockett M,Tuomala RE,Rutherford AE,Mutinga ML,Andersson KL,Brown RS Jr,Oken E,Ukomadu C

    更新日期:2016-07-01 00:00:00

  • Ultrasonography-guided percutaneous radiofrequency ablation for treatment of a huge symptomatic hepatic cavernous hemangioma.

    abstract::Hepatic cavernous hemangioma is the most common benign tumor of the liver. Appropriate management of this tumor remains a controversial topic. We have accumulated a number of cases with successful management of local hepatic tumors. Here we report a case where we performed an ultrasound-guided percutaneous radiofreque...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/01.mcg.0000196404.07487.1d

    authors: Tak WY,Park SY,Jeon SW,Cho CM,Kweon YO,Kim SK,Choi YH,Chung JM

    更新日期:2006-02-01 00:00:00

  • Evaluation of the Esophagogastric Junction on High Resolution Manometry.

    abstract::The esophagogastric junction (EGJ) is a complex barrier between the thoracic and abdominal luminal gut compartments, comprised primarily of the lower esophageal sphincter (LES) and crural diaphragm. Although closed at rest, the EGJ relaxes to allow antegrade bolus transit and retrograde venting of air. Abnormal relaxa...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000001474

    authors: Rogers BD,Gyawali CP

    更新日期:2021-02-01 00:00:00

  • Cyclic vomiting associated with excessive dopamine in Riley-day syndrome.

    abstract:GOALS:To analyze the neurochemical profile during the recurrent attacks of nausea and vomiting in patients with Riley-day syndrome. BACKGROUND:One of the most disabling features of patients with Riley-day syndrome are recurrent attacks of severe nausea/retching/vomiting accompanied by hypertension, tachycardia, and sk...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e3182582cbf

    authors: Norcliffe-Kaufmann LJ,Axelrod FB,Kaufmann H

    更新日期:2013-02-01 00:00:00

  • Inability to noninvasively diagnose gastric intestinal metaplasia in Hispanics or reverse the lesion with Helicobacter pylori eradication.

    abstract:BACKGROUND:Helicobacter pylori infection has been linked with the development of gastric adenocarcinoma and its precursor lesion, intestinal metaplasia (IM). The presence of gastric IM is not associated with symptoms, which makes identification of individuals with this lesion difficult. It is not clear whether eradicat...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00004836-200105000-00008

    authors: Morales TG,Sampliner RE,Camargo E,Marquis S,Garewal HS,Fennerty MB

    更新日期:2001-05-01 00:00:00

  • Jejunal water and sodium secretion occurs in chronic idiopathic intestinal pseudo-obstruction.

    abstract::We observed jejunal water and sodium secretion in two patients with chronic idiopathic intestinal pseudo-obstruction by standard perfusion techniques. The ability of glucose to reverse this secretory state was impaired. These observations suggest that a jejunal secretory state may contribute to the diarrhea in chronic...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199004000-00008

    authors: Rolston DD,Hunt JB,Fairclough PD,Wilks M,Levison DA,Clark ML,Farthing MJ

    更新日期:1990-04-01 00:00:00

  • Gunshot cholecystitis.

    abstract::A 15-year-old boy developed traumatic cholecystitis from a BB shot that lodged in his gallbladder. This is an unusual cause of gallbladder disease, and we review the literature. ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/00004836-199512000-00016

    authors: Petersen JM,Knight TT

    更新日期:1995-12-01 00:00:00

  • A laboratory score in the diagnosis of autoimmune atrophic gastritis: a prospective study.

    abstract:BACKGROUND:Several biomarkers have been proposed for the diagnosis of autoimmune atrophic gastritis (AAG), but at the present there is no appropriate testing strategy for the disease. GOALS:The aim of this study was to develop and validate a laboratory score able to address the diagnosis of AAG in a general practice s...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000101

    authors: Miceli E,Padula D,Lenti MV,Gallia A,Albertini R,Di Stefano M,Klersy C,Corazza GR

    更新日期:2015-01-01 00:00:00

  • Lactobacillus casei subsp. rhamnosus sepsis in a patient with ulcerative colitis.

    abstract::Lactobacillus species are part of normal gastrointestinal flora and are an uncommon cause of bacteremia. Lactobacillus casei subsp. rhamnosus was repeatedly isolated in the blood cultures of a 43-year-old woman with ulcerative colitis. Lactobacillus spp. could be considered a potential opportunistic pathogen whenever ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200109000-00019

    authors: Farina C,Arosio M,Mangia M,Moioli F

    更新日期:2001-09-01 00:00:00