A comparison of the microbial flora in carious dentine of clinically detectable and undetectable occlusal lesions.

Abstract:

:It is not known whether the aetiology of occlusal hidden caries lesions (HCL) is identical to that of small visible lesions (SVL). Previous studies of the microflora of HCL suggest that relatively few species can be isolated. The aim of the present study was to compare the bacterial composition of dentine from 10 HCL and 17 SVL in a population of children aged 8-18 years. The following bacteria were identified: Actinomyces spp., mutans streptococci, Streptococcus sanguis, Streptococcus oralis, Streptococcus gordonii. Streptococcus mitis, and Lactobacillus spp. Streptococcus mutans was found more often in the HCL group (p = 0.03), while Streptococcus sobrinus was found more often in the SVL group (p = 0.05). However, proportions of both species were lower in the SVL group as compared with the HCL group (S. mutans p = 0.07; S. sobrinus p = 0.03). Lactobacilli and Actinomyces spp. were found at similar levels in both groups. A more diverse range of streptococcal species and Veillonella was found in the SVL group (p = 0.001). These results show a less complex microflora in HCL as compared with SVL, indicating that the aetiology of hidden caries might be different from that of open caries.

journal_name

Caries Res

journal_title

Caries research

authors

de Soet JJ,Weerheijm KL,van Amerongen WE,de Graaff J

doi

10.1159/000262039

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

46-9

issue

1

eissn

0008-6568

issn

1421-976X

journal_volume

29

pub_type

杂志文章
  • Inhibition of Streptococcus mutans Growth and Biofilm Formation by Probiotics in vitro.

    abstract::To exert anticaries effects, probiotics are described to inhibit growth and biofilm formation of cariogenic bacteria such as Streptococcus mutans (SM). We screened 8 probiotics and assessed how SM growth or biofilm formation inhibition affects cariogenicity of probiotic-SM mixed-species biofilms in vitro. Growth inhib...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000452960

    authors: Schwendicke F,Korte F,Dörfer CE,Kneist S,Fawzy El-Sayed K,Paris S

    更新日期:2017-01-01 00:00:00

  • Infant Growth and the Occurrence of Developmental Defects of Enamel in 12-Year-Olds.

    abstract:BACKGROUND/AIMS:To investigate the association between birth weight and infant growth during the first year of life and the occurrence of developmental defects of enamel (DDE) in permanent dentition. METHODS:A random sample of 668 12-year-old students was recruited from a birth cohort. Permanent incisors and first mol...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000381425

    authors: Wong HM,Peng SM,King NM,McGrath C

    更新日期:2015-01-01 00:00:00

  • Digital radiography of interproximal caries: effect of different filters.

    abstract::The aim of this study was to compare the effect of different image processing modes (filters) on reproducibility and validity of the assessment of interproximal carious lesions on digitized radiographic images. Standardized radiographs of 34 extracted teeth exhibiting interproximal caries were obtained. All radiograph...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000016522

    authors: Eickholz P,Kolb I,Lenhard M,Hassfeld S,Staehle H

    更新日期:1999-05-01 00:00:00

  • Remineralizing Potential of a Low Fluoride Toothpaste with Sodium Trimetaphosphate: An in situ Study.

    abstract:OBJECTIVE:To evaluate the effect of a low-fluoride (F) toothpaste supplemented with sodium trimetaphosphate (TMP) on enamel remineralization in situ. DESIGN:Bovine enamel blocks were selected on the basis of their surface hardness (SH) after caries-like lesions had been induced, and randomly divided into 4 treatment g...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000449358

    authors: Takeshita EM,Danelon M,Castro LP,Cunha RF,Delbem AC

    更新日期:2016-01-01 00:00:00

  • Influence of fluoridated salt on urinary fluoride excretion of adults.

    abstract::After the introduction of fluoridated table salt in the staff cafeteria (VZM) of the Heidelberg University Medical and Dental School, the opportunity was taken to determine urinary fluoride excretion of those eating their main daily meals there. Subjects collected 24-hour urine in three fractions (mornings, afternoons...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000066540

    authors: Schulte AG,Gräber R,Kasperk C,Koch MJ,Staehle HJ

    更新日期:2002-11-01 00:00:00

  • Effect of a calcium carbonate-based dentifrice on in situ enamel remineralization.

    abstract::This crossover study evaluated the effect of calcium carbonate (CaCO(3))-based monofluorophosphate dentifrice on enamel remineralization. Ten volunteers wore palatal appliances containing four enamel blocks with caries-like lesions, two of them covered by a test plaque of mutans streptococci. The following treatments ...

    journal_title:Caries research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000084807

    authors: Cury JA,Simões GS,Del Bel Cury AA,Gonçalves NC,Tabchoury CP

    更新日期:2005-05-01 00:00:00

  • Minimal Gap Size and Dentin Wall Lesion Development Next to Resin Composite in a Microcosm Biofilm Model.

    abstract::This in vitro study investigated the development of dentin wall lesions next to resin composite containing very small gap sizes using an in vitro biofilm model, and evaluated whether a relevant threshold for the gap size could be established. Microcosm biofilms were grown for 14 days within small interfacial gaps betw...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000478536

    authors: Maske TT,Kuper NK,Cenci MS,Huysmans MDNJM

    更新日期:2017-01-01 00:00:00

  • Effectiveness of Resin-Based Sealants with and without Fluoride Placed in a High Caries Risk Population: Multicentric 2-Year Randomized Clinical Trial.

    abstract::A split-mouth randomized clinical trial was carried out to assess the effectiveness of sealants in preventing carious ICDAS (International Caries Detection and Assessment System) 3-6 lesions within a 2-year follow-up. We evaluated the effectiveness of 2 types of resin-based sealants, with and without fluoride, their r...

    journal_title:Caries research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1159/000486426

    authors: Muller-Bolla M,Courson F,Lupi-Pégurier L,Tardieu C,Mohit S,Staccini P,Velly AM

    更新日期:2018-01-01 00:00:00

  • Characterization of the arginolytic microflora provides insights into pH homeostasis in human oral biofilms.

    abstract::A selected group of oral bacteria commonly associated with dental health is capable of producing alkali via the arginine deiminase system (ADS), which has a profound impact on the pH of human oral biofilms. An increased risk for dental caries has been associated with reduced ADS activity of the bacteria in oral biofil...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000365296

    authors: Huang X,Schulte RM,Burne RA,Nascimento MM

    更新日期:2015-01-01 00:00:00

  • Fluoride and calcium content of enamel organ, muscle, liver and plasma in rats.

    abstract::Nine-day-old rats were given oral fluoride doses (0.5 micrograms F/g body weight). Plasma, enamel organ, muscle and liver samples were collected from nondosed pups (baseline) and 15, 30, 60 and 120 min after the dose. Samples were assayed for fluoride and calcium concentrations. Adult rats were given 20 ppm F water fo...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261449

    authors: Bawden JW,Deaton TG,Crawford BP

    更新日期:1992-01-01 00:00:00

  • The reliability and accuracy of two methods for proximal caries detection and depth on directly visible proximal surfaces: an in vitro study.

    abstract::This study aimed to determine the reliability and accuracy of the ICDAS and radiographs in detecting and estimating the depth of proximal lesions on extracted teeth. The lesions were visible to the naked eye. Three trained examiners scored a total of 132 sound/carious proximal surfaces from 106 primary teeth and 160 s...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000324439

    authors: Ekstrand KR,Luna LE,Promisiero L,Cortes A,Cuevas S,Reyes JF,Torres CE,Martignon S

    更新日期:2011-01-01 00:00:00

  • Histological validation of electrical resistance measurements in the diagnosis of occlusal caries.

    abstract::Diagnosis of occlusal caries is difficult from visual and radiographic examination. The use of electrical resistance measurement has been described previously and reported to be a potentially sensitive alternative technique. This is possibly due to the decreased resistance of carious pits and fissures. The aim of this...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000262152

    authors: Ricketts DN,Kidd EA,Liepins PJ,Wilson RF

    更新日期:1996-01-01 00:00:00

  • The effects of acidic fluoride solutions on early enamel erosion in vivo.

    abstract::Acidic fluoride solutions may reduce dental erosion. The aim of this study was to compare the effect of different acidic fluoride solutions on enamel dissolution using an established in vivo model. When possible 4 anterior teeth (255 teeth in a total of 67 subjects) were isolated and exposed to 0.01 M citric acid. The...

    journal_title:Caries research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000209345

    authors: Hjortsjö C,Jonski G,Thrane PS,Saxegaard E,Young A

    更新日期:2009-01-01 00:00:00

  • Efficacy of preventive agents for dental caries. Systemic fluorides: water fluoridation.

    abstract::The effectiveness of fluoridation has been documented by observational and interventional studies for over 50 years. Data are available from 113 studies in 23 countries. The modal reduction in DMFT values for primary teeth was 40-49% and 50-59% for permanent teeth. The pattern of caries now occurring in fluoride and l...

    journal_title:Caries research

    pub_type: 杂志文章,评审

    doi:10.1159/000261594

    authors: Murray JJ

    更新日期:1993-01-01 00:00:00

  • A randomised, observer-blind, clinical study investigating the effect of fluoridated milk on artificially created early enamel caries using transverse microradiography.

    abstract::Much of the research regarding the efficacy of fluoridated milk was obtained prior to the routine use of fluoridated dentifrices. The aim was to investigate, in situ, the effect of fluoridated and non-fluoridated milk on mineral change in artificial caries lesions, with the additional use of fluoridated dentifrice. Th...

    journal_title:Caries research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000148163

    authors: Nicol AJ,Creanor S,Hall AF,Macpherson LM

    更新日期:2008-01-01 00:00:00

  • Casein Phosphopeptide-Amorphous Calcium Phosphate Attenuates Virulence and Modulates Microbial Ecology of Saliva-Derived Polymicrobial Biofilms.

    abstract:BACKGROUND:Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) acts as a salivary biomimetic that provides bioavailable calcium and phosphate ions to augment fluoride-mediated remineralisation of early caries lesions. However, there are indications that it may also have beneficial ecological effects on the oral...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000499869

    authors: Philip N,Leishman SJ,Bandara HMHN,Walsh LJ

    更新日期:2019-01-01 00:00:00

  • A method for the quantitative site-specific study of the biochemistry within dental plaque biofilms formed in vivo.

    abstract::The study of plaque biofilms in the oral cavity is difficult as plaque removal inevitably disrupts biofilm integrity precluding kinetic studies involving the penetration of components and metabolism of substrates in situ. A method is described here in which plaque is formed in vivo under normal (or experimental) condi...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000262398

    authors: Robinson C,Kirkham J,Percival R,Shore RC,Bonass WA,Brookes SJ,Kusa L,Nakagaki H,Kato K,Nattress B

    更新日期:1997-01-01 00:00:00

  • Determination of fluoride intake from urinary fluoride excretion data in children drinking fluoridated school milk.

    abstract::Twenty-four-hour urine samples were collected from each of thirteen 5- to 6-year-old children both under customary conditions of fluoride intake (i.e. usual diet including milk containing 0.5 mg fluoride and usual oral hygiene procedures with fluoride toothpaste) and during a 4-day study period in which their customar...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000047466

    authors: Ketley CE,Lennon MA

    更新日期:2001-07-01 00:00:00

  • Trends in caries prevalence in 5-, 7- and 11-year-old schoolchildren in The Hague between 1969 and 1989.

    abstract::Starting in 1969, periodic cross-sectional examinations of schoolchildren have been carried out in the city of The Hague. In 1989 the periodic examinations were continued and, in general, caries prevalence was found to be very low; D3MFS values ranged between 1.5 and 2.2 at age 11.8 years. Compared to 1984, 5-year-old...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261412

    authors: Truin GJ,König KG,de Vries HC,Mulder J,Plasschaert AJ

    更新日期:1991-01-01 00:00:00

  • Approximal caries development in adolescents with low to moderate caries risk after different 3-year school-based supervised fluoride mouth rinsing programmes.

    abstract::The aim was to evaluate a 3-year randomised controlled trial of school-based fluoride mouth rinsing (FMR) on approximal caries development in 13- to 16-year-olds with low to moderate caries risk. The adolescents used F toothpaste at home and underwent prophylactic treatment at yearly check-ups at public dental clinics...

    journal_title:Caries research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000088191

    authors: Moberg Sköld U,Birkhed D,Borg E,Petersson LG

    更新日期:2005-11-01 00:00:00

  • Diagnostic Accuracy of a Bioluminescence System for the Assessment of Caries Activity on Occlusal Surfaces.

    abstract:OBJECTIVE:Assessment of caries lesion activity is usually performed using visual-tactile criteria. A new approach is to use a system consisting of a photoprotein, which is specific for free calcium ions, along with an integrated camera that visualizes the elevated calcium ions on the lesion as a light signal (biolumine...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000486139

    authors: Jablonski-Momeni A,Moos J,Sakhaei Manesh V,Stoll R

    更新日期:2018-01-01 00:00:00

  • Diversity in Antagonistic Interactions between Commensal Oral Streptococci and Streptococcus mutans.

    abstract::Arginine metabolism via the arginine deiminase system (ADS) of oral bacteria generates ammonia, which can increase the pH of oral biofilms and decrease the risk for dental caries. Antagonistic interactions between ADS-positive and cariogenic bacteria in oral biofilms may be an important ecological determinant of carie...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000479091

    authors: Huang X,Browngardt CM,Jiang M,Ahn SJ,Burne RA,Nascimento MM

    更新日期:2018-01-01 00:00:00

  • Dental caries. Principal cause of tooth extraction in a sample of US male adults.

    abstract::Comprehensive oral examinations carried out over a period of about 10 years on participants in the Veterans Administration Dental Longitudinal Study were evaluated to identify teeth extracted during this time and to ascertain the apparent reason for these extractions. The study population included 736 dentulous adult ...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261178

    authors: Chauncey HH,Glass RL,Alman JE

    更新日期:1989-01-01 00:00:00

  • Dental plaque as a microbial biofilm.

    abstract::New technologies have provided novel insights into how dental plaque functions as a biofilm. Confocal microscopy has confirmed that plaque has an open architecture similar to other biofilms, with channels and voids. Gradients develop in areas of dense biomass over short distances in key parameters that influence micro...

    journal_title:Caries research

    pub_type: 杂志文章,评审

    doi:10.1159/000077756

    authors: Marsh PD

    更新日期:2004-05-01 00:00:00

  • Noncariogenicity of erythritol as a substrate.

    abstract::Erythritol is a sugar alcohol produced by Aureobasidium sp. from glucose. It is 75-80% as sweet as sucrose and is also nonhygroscopic. The aim of this study was to evaluate this sugar substitute from a cariological point of view. Erythritol was neither utilized as a substrate for the lactic acid production nor for pla...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261468

    authors: Kawanabe J,Hirasawa M,Takeuchi T,Oda T,Ikeda T

    更新日期:1992-01-01 00:00:00

  • Ultrasonic determination of the effect of casein phosphopeptide-amorphous calcium phosphate paste on the demineralization of bovine dentin.

    abstract::The purpose of this study was to investigate the demineralization of dentin by measuring changes in the velocity of the sonic longitudinal waves transmitted through this substrate. One group of samples was immersed in demineralization solution for 10 min twice a day and then stored in artificial saliva. Two additional...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000099319

    authors: Yamaguchi K,Miyazaki M,Takamizawa T,Inage H,Kurokawa H

    更新日期:2007-01-01 00:00:00

  • Acid resistance of enamel subsurface lesions remineralized by a sugar-free chewing gum containing casein phosphopeptide-amorphous calcium phosphate.

    abstract::The aim of this clinical study was to investigate the acid resistance of enamel lesions remineralized in situ by a sugar-free chewing gum containing casein phosphopeptide-amorphous calcium phosphate nanocomplexes (CPP-ACP: Recaldent). The study utilized a double-blind, randomized, crossover design with two treatments:...

    journal_title:Caries research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000080585

    authors: Iijima Y,Cai F,Shen P,Walker G,Reynolds C,Reynolds EC

    更新日期:2004-11-01 00:00:00

  • Effect of salivary stimulation on erosion of human and bovine enamel subjected or not to subsequent abrasion: an in situ/ex vivo study.

    abstract::This in situ/ex vivo study evaluated whether saliva stimulated by chewing gum could prevent or reduce the wear and the percent change in microhardness (%SMH) of bovine and human enamel submitted to erosion followed by brushing abrasion immediately or after 1 h. During 2 experimental 7-day crossover phases, 9 previousl...

    journal_title:Caries research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000092229

    authors: Rios D,Honório HM,Magalhães AC,Delbem AC,Machado MA,Silva SM,Buzalaf MA

    更新日期:2006-01-01 00:00:00

  • Polychlorinated biphenyls cause developmental enamel defects in children.

    abstract::The aim of this study was to evaluate the effects of long-term exposure to polychlorinated biphenyls (PCBs) on developing dental enamel. 202 8- to 14-year-old children who were pre- and post-natally exposed to PCBs in the contaminated region of Bela Krajina, Slovenia, were studied. 202 controls from Brsljin were match...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000016625

    authors: Jan J,Vrbic V

    更新日期:2000-11-01 00:00:00

  • Five-year incidence of coronal and root caries in 60-, 70- and 80-year-old Swedish individuals.

    abstract::The 5-year incidence of caries was studied in a random sample of 60-, 70- and 80-year-old inhabitants of Göteborg, with 69, 51 and 28 individuals in the different age groups. One aim of the study was to introduce a root caries index (DMFRS%) in which the missing root surfaces are taken into account. This study, as wel...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000262408

    authors: Fure S

    更新日期:1997-01-01 00:00:00