Fluoride and calcium content of enamel organ, muscle, liver and plasma in rats.

Abstract:

:Nine-day-old rats were given oral fluoride doses (0.5 micrograms F/g body weight). Plasma, enamel organ, muscle and liver samples were collected from nondosed pups (baseline) and 15, 30, 60 and 120 min after the dose. Samples were assayed for fluoride and calcium concentrations. Adult rats were given 20 ppm F water for 6 weeks, and the same tissues were sampled and assayed for fluoride concentrations only. In the first phase of the study, enamel organ had significantly higher fluoride and calcium content than liver and muscle. In adult rats the fluoride content of enamel organ was again significantly higher than for liver and muscle.

journal_name

Caries Res

journal_title

Caries research

authors

Bawden JW,Deaton TG,Crawford BP

doi

10.1159/000261449

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

263-7

issue

4

eissn

0008-6568

issn

1421-976X

journal_volume

26

pub_type

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