Abstract:
:Nine-day-old rats were given oral fluoride doses (0.5 micrograms F/g body weight). Plasma, enamel organ, muscle and liver samples were collected from nondosed pups (baseline) and 15, 30, 60 and 120 min after the dose. Samples were assayed for fluoride and calcium concentrations. Adult rats were given 20 ppm F water for 6 weeks, and the same tissues were sampled and assayed for fluoride concentrations only. In the first phase of the study, enamel organ had significantly higher fluoride and calcium content than liver and muscle. In adult rats the fluoride content of enamel organ was again significantly higher than for liver and muscle.
journal_name
Caries Resjournal_title
Caries researchauthors
Bawden JW,Deaton TG,Crawford BPdoi
10.1159/000261449subject
Has Abstractpub_date
1992-01-01 00:00:00pages
263-7issue
4eissn
0008-6568issn
1421-976Xjournal_volume
26pub_type
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