Abstract:
:The mechanistic action of fluoride on inhibition of enamel demineralization was investigated using (19)F magic angle spinning nuclear magnetic resonance (MAS-NMR). The aim of this study was to monitor the fluoride-mineral phase formed on the enamel as a function of the concentration of fluoride ions [F(-)] in the demineralizing medium. The secondary aim was to investigate fluorapatite formation on enamel in the mechanism of fluoride anti-caries efficacy. Enamel blocks were immersed into demineralization solutions of 0.1 M acetic acid (pH 4) with increasing concentrations of fluoride up to 2,262 ppm. At and below 45 ppm [F(-)] in the solution, (19)F MAS-NMR showed fluoride-substituted apatite formation, and above 45 ppm, calcium fluoride (CaF2) formed in increasing proportions. Further increases in [F(-)] caused no further reduction in demineralization, but increased the proportion of CaF2 formed. Additionally, the combined effect of strontium and fluoride on enamel demineralization was also investigated using (19)F MAS-NMR. The presence of 43 ppm [Sr(2+)] in addition to 45 ppm [F(-)] increases the fraction of fluoride-substituted apatite, but delays formation of CaF2 when compared to the demineralization of enamel in fluoride-only solution.
journal_name
Caries Resjournal_title
Caries researchauthors
Mohammed NR,Kent NW,Lynch RJ,Karpukhina N,Hill R,Anderson Pdoi
10.1159/000350171subject
Has Abstractpub_date
2013-01-01 00:00:00pages
421-8issue
5eissn
0008-6568issn
1421-976Xpii
000350171journal_volume
47pub_type
杂志文章相关文献
CARIES RESEARCH文献大全abstract::Bone morphogenetic proteins (BMPs) play an important role during the initial process of enamel development and therefore may play a role in caries susceptibility. The purpose of this study was to evaluate the association between the polymorphisms in the BMP2, BMP4 and BMP7 genes and their association with caries exper...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000371715
更新日期:2015-01-01 00:00:00
abstract::Some antimicrobial compounds were tested for their antiplaque activity by a simple method involving measurement of the weight of Streptococcus sobrinus plaque on a glass surface. Chlorhexidine, cetylpyridinium chloride, and n-tetradecylamine reduced the weight of plaque produced by S. sobrinus in vitro; some N-palmity...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261250
更新日期:1990-01-01 00:00:00
abstract::The crowns of 60 permanent human molars were sectioned transversally. The exposed dentin surface was divided into different parts: a first part was kept as control, a second part was immediately varnished, and a third part was irradiated with a CO2 laser using the same irradiation conditions as those applied for carie...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261438
更新日期:1992-01-01 00:00:00
abstract::Mutans streptococci (MS) and lactobacillus (LB) counts (CRT Bacteria chair-side test) were compared and correlated with the respective caries experience (DMF) of cystic fibrosis (CF) homozygotes (n = 20), CF heterozygotes (n = 20) and healthy controls (n = 20). Each group of subjects was divided into two equal age gro...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000047483
更新日期:2001-11-01 00:00:00
abstract::The aim of this study was to compare the effect of different image processing modes (filters) on reproducibility and validity of the assessment of interproximal carious lesions on digitized radiographic images. Standardized radiographs of 34 extracted teeth exhibiting interproximal caries were obtained. All radiograph...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016522
更新日期:1999-05-01 00:00:00
abstract::The aim of this study was to identify risk determinants leading to early childhood caries (ECC) and visible plaque (VP) in toddlers. Data for mother-child pairs participating in the Growing Up in Singapore towards Healthy Outcomes (GUSTO) birth cohort were collected from pregnancy to toddlerhood. Oral examinations wer...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000471811
更新日期:2017-01-01 00:00:00
abstract::Metalloproteinases (MMPs) have been implicated with metabolism of collagen in physiological and pathological processes in human dentine. As bovine teeth have been used as a substitute for human teeth in laboratory analysis, this study evaluated the activity of MMP-2 and -9 in bovine versus human dentine. Bovine and hu...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000330525
更新日期:2011-01-01 00:00:00
abstract::Much of the research regarding the efficacy of fluoridated milk was obtained prior to the routine use of fluoridated dentifrices. The aim was to investigate, in situ, the effect of fluoridated and non-fluoridated milk on mineral change in artificial caries lesions, with the additional use of fluoridated dentifrice. Th...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000148163
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) acts as a salivary biomimetic that provides bioavailable calcium and phosphate ions to augment fluoride-mediated remineralisation of early caries lesions. However, there are indications that it may also have beneficial ecological effects on the oral...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000499869
更新日期:2019-01-01 00:00:00
abstract::In 1995, a dental survey was performed among adults aged 25-54 in the Dutch city of 's-Hertogenbosch. A similar study was performed in the same city in 1983 and the aim of the present study was to describe trends in oral health from 1983 to 1995. National data show that the percentage of edentulous persons aged 30-39 ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016448
更新日期:1998-01-01 00:00:00
abstract::This paper describes the dental health status of Italian 4-year-olds in 2004/2005 and analyzes the association between caries in preschool children and some background characteristics in children and parents. Caries was recorded according to WHO criteria. 5,538 subjects were examined. Information on the children's and...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000211719
更新日期:2009-01-01 00:00:00
abstract::The aim of this study was to identify the association of the presence of root caries in older people with contextual and individual determinants using a multilevel model. Data from the National Survey of Oral Health collected in Brazil were used. A sample of older Brazilians (aged 65-74 years) was included and selecte...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000479800
更新日期:2018-01-01 00:00:00
abstract::This in vivo study aimed to compare the performance of different methods of approximal caries detection in primary molars. Fifty children (aged 5-12 years) were selected, and 2 examiners evaluated 621 approximal surfaces of primary molars using: (a) visual inspection, (b) the radiographic method and (c) a pen-type las...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000189705
更新日期:2009-01-01 00:00:00
abstract::Although chlorhexidine is one of the most efficacious antimicrobial agents used for the prevention of dental caries, side effects limit its application. The effects of gaegurin 6 (GGN6), an animal-derived cationic peptide, and its derivatives PTP6 and PTP12 on the growth of oral streptococci were investigated to asses...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000073394
更新日期:2003-11-01 00:00:00
abstract::The purpose of the study was to determine whether adding calcium lactate to chewing gum containing xylitol enhances remineralization of enamel surfaces using an early caries lesion model. Enamel slabs were cut from human extracted sound teeth and artificial subsurface lesions created within each. Half the enamel slabs...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000088905
更新日期:2006-01-01 00:00:00
abstract::In the present in vitro study, the validity was determined of bite-wing radiographs for the diagnosis of secondary caries in approximal parts of teeth with class II amalgam restorations in vitro. The study was performed on 47 molars and 49 premolars providing 68 and 69 filled approximal surfaces, respectively. The tee...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262369
更新日期:1997-01-01 00:00:00
abstract::There are few longitudinal studies in which the development of caries over a long period of time has been studied for different age groups. Such studies are important because they can provide information to assess future needs for dental care and the implications if the development of caries is different for patients ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000381427
更新日期:2015-01-01 00:00:00
abstract::The purpose of this in vitro study was to assess the validity and reproducibility of the diagnosis of fissure caries prior to and following the placement of a clear sealant. One hundred and twelve extracted molar teeth were examined by 7 experienced clinicians. Each examiner conducted four visual examinations, 2 prior...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262096
更新日期:1995-01-01 00:00:00
abstract::The aim was to study the salivary fluoride (F) concentration and plaque pH recovery on the chewing and the non-chewing side of the dentition during and after chewing 1 piece of chewing gum containing 0.25 mg F as NaF. Ten subjects refrained from toothbrushing for 3 days. On the fourth day, they rinsed for 1 min with 1...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000262420
更新日期:1997-01-01 00:00:00
abstract::Pooled plaque samples were obtained from (1) coronal surfaces of two groups of caries-free (CF) subjects, (2) coronal 'white-spot' surface areas of a group of caries-positive (CP) subjects, and (3) exposed, sound root surfaces of root caries-free (RCF) and root caries-positive (RCP) subjects. The plaque samples were o...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261582
更新日期:1993-01-01 00:00:00
abstract::An occlusal restoration is usually considered necessary when a lesion extends into the dentin. This study aimed to assess the relationship between the clinical appearance of occlusal caries and the lesion depth. Special attention was paid to differentiate the inner, partly demineralitzed layer of carious dentin that s...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262003
更新日期:1994-01-01 00:00:00
abstract::The aim of this in vitro study was to investigate the impact of saliva on the abrasion of eroded enamel using two measuring methods. A total of 80 bovine enamel specimens from 20 bovine incisors were allocated to four experimental groups (n = 20 specimens per group). After baseline surface microhardness (SMH) measurem...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000489133
更新日期:2019-01-01 00:00:00
abstract::An oral health care programme in secondary schools using the atraumatic restorative treatment (ART) approach for dental caries was started in 1993. Glass ionomer (restorative type II, 1) was used as the restorative and sealant material. Sealants were placed using the 'press-finger' technique. Results after 3 years rev...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016441
更新日期:1998-01-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the effectiveness of partial removal of carious dentine and restoration in a single session (PDR) and stepwise excavation (SW), both of which are treatments for deep carious lesions, in Public Health Services in Brazil. METHODS: INCLUSION CRITERIA:patients ≥6 years old, perma...
journal_title:Caries research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000344013
更新日期:2013-01-01 00:00:00
abstract::Ion-sensitive field-effect transistor (ISFET) pH electrodes were used to monitor changes in plaque pH at the base of artificial occlusal surface fissures and at interproximal sites. Bovine enamel was used to construct fissures (1.5 x 0.1 x 1.0 mm) containing a small ISFET electrode. The fissures were fixed to carrier ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261220
更新日期:1989-01-01 00:00:00
abstract::Adhesion of bacteria to pellicle-coated tooth surfaces is the first step in biofilm formation on teeth. The aim of this study was to explore whether human milk prevents or promotes adhesion of cariogenic Streptococcus mutans to saliva-coated hydroxyapatite (HA) using an in vitro model system. S. mutans binding to HA c...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000094287
更新日期:2006-01-01 00:00:00
abstract::Streptococcus mutans and Streptococcus sobrinus are associated with the development of dental caries. The purpose of this study was to differentiate these bacteria by morphology, biochemical characteristics and PCR, and to compare their occurrence with the prevalence of dental caries in the Mosuo people. Plaque sample...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000072171
更新日期:2003-09-01 00:00:00
abstract::The remineralization of whole human dentine treated with a neutral EDTA solution was investigated: the treatment periods were 15, 30 and 120 min. From the literature it is known that EDTA removes noncollagenous proteins (NCPs) from dentine powders. In order to extract more phosphoproteins from dentine lesions, in part...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016529
更新日期:1999-07-01 00:00:00
abstract::The problem of identifying potential determinants and predictors of dental caries is of key importance in caries research and it has received considerable attention in the scientific literature. From the methodological side, a broad range of statistical models is currently available to analyze dental caries indices (D...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000369831
更新日期:2015-01-01 00:00:00
abstract::Erythritol is a sugar alcohol produced by Aureobasidium sp. from glucose. It is 75-80% as sweet as sucrose and is also nonhygroscopic. The aim of this study was to evaluate this sugar substitute from a cariological point of view. Erythritol was neither utilized as a substrate for the lactic acid production nor for pla...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261468
更新日期:1992-01-01 00:00:00