Antibacterial activity of polyphenol components in oolong tea extract against Streptococcus mutans.

Abstract:

:The purpose of the present study was to determine the antibacterial activity of oolong tea extract on oral streptococci, including Streptococcus mutans and Streptococcus sobrinus, and to identify the response to its components. Antibacterial activity was found when the extract was added to S. mutans cells in chemically defined medium but not in complex broth media. Further, pretreatment with bovine serum albumin reduced the antibacterial activity. The extract showed antibacterial activity against all of the oral streptococci examined, with the highest activity against S. mutans MT8148R. This activity was found to originate from a monomeric polyphenol-rich fraction, and it was stronger than that of pure polyphenols. Moreover, some combinations of monomeric polyphenols showed the highest level of antibacterial activity. These results suggest that the antibacterial activity of oolong tea extract is caused by a synergistic effect of monomeric polyphenols, which can easily bind to proteins.

journal_name

Caries Res

journal_title

Caries research

authors

Sasaki H,Matsumoto M,Tanaka T,Maeda M,Nakai M,Hamada S,Ooshima T

doi

10.1159/000073913

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

2-8

issue

1

eissn

0008-6568

issn

1421-976X

pii

73913

journal_volume

38

pub_type

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