Coadministration of fluvoxamine increases serum concentrations of haloperidol.

abstract：:The current study uses utility analysis to assess economic and quality-of-life benefits of risperidone in patients with chronic schizophrenia. A retrospective analysis was performed on Positive and Negative Syndrome Symptoms (PANSS) data obtained from the published Canadian multicenter risperidone trial (part of the N...

journal_title：Journal of clinical psychopharmacology

authors： Chouinard G,Albright PS

更新日期：1997-08-01 00:00:00

abstract：:A study of medication compliance, side effects, and clinical change with the use of antidepressants in 32 Southeast Asian refugee patients seen at an urban mental health center is reported. Patients met criteria for either major depressive episode, posttraumatic stress disorder, or both. Only five of the 32 patients w...

journal_title：Journal of clinical psychopharmacology

authors： Kroll J,Linde P,Habenicht M,Chan S,Yang M,Vang T,Souvannasoth L,Nguyen T,Ly M,Nguyen H

更新日期：1990-08-01 00:00:00

abstract：:In an open prospective clinical study, 14 female outpatients with anorexia nervosa or bulimia completed a 6-week trial of isocarboxazid, with a mean dose of 34 mg. The eight bulimic and six restrictive anorexic subjects did not show any significant differences in medication response. Ratings of depression and anxiety ...

journal_title：Journal of clinical psychopharmacology

authors： Kennedy SH,Piran N,Garfinkel PE

更新日期：1985-10-01 00:00:00

abstract：PURPOSE/BACKGROUND:For approximately one third of individuals treated for psychosis or schizophrenia, antipsychotic medications will have little or no therapeutic benefit. Clozapine remains the sole medication approved for treatment-resistant schizophrenia, and studies have demonstrated its superior efficacy in reducin...

journal_title：Journal of clinical psychopharmacology

authors： Doyle R,Behan C,OʼKeeffe D,Masterson S,Kinsella A,Kelly A,Sheridan A,Keating D,Hynes C,Madigan K,Lawlor E,Clarke M

更新日期：2017-10-01 00:00:00

abstract：:In this study, the authors investigated the relationship between the metabolism of clomipramine (C) and the genotypes of cytochrome P450 (CYP) CYP2C19 and CYP2D6. Fifty-one Japanese patients (18 men and 33 women) were administered 10 to 250 mg/day of C by mouth and maintained on the same daily dose of C for at least 2...

journal_title：Journal of clinical psychopharmacology

authors： Yokono A,Morita S,Someya T,Hirokane G,Okawa M,Shimoda K

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:Researchers, by studying first-generation antipsychotics, have established an early prediction model, which had a favorable specificity but a low sensitivity. This study aims to optimize early prediction of treatment response for schizophrenia using a novel statistic method that can be done even under the Mic...

journal_title：Journal of clinical psychopharmacology

authors： Chang YC,Lane HY,Yang KH,Huang CL

更新日期：2006-12-01 00:00:00

abstract：:The potential for iloperidone, a D2/5-HT2A antipsychotic, to affect the heart rate-corrected QT interval (QTc) was assessed in the absence and presence of metabolic inhibitors in a randomized, open-label, multicenter study. QT interval prolongation by medications, including both conventional and atypical antipsychotic...

journal_title：Journal of clinical psychopharmacology

authors： Potkin SG,Preskorn S,Hochfeld M,Meng X

更新日期：2013-02-01 00:00:00

abstract：:Although many patients with major depressive disorder (MDD) complain of neurocognitive impairment, the effects of antidepressant medications on neurocognitive functions remain unclear. This study compares neurocognitive effects of tianeptine and escitalopram in MDD. Patients with MDD (N = 164) were randomly assigned i...

journal_title：Journal of clinical psychopharmacology

authors： Jeon HJ,Woo JM,Lee SH,Kim EJ,Chung S,Ha JH,Fava M,Mischoulon D,Kim JH,Heo JY,Yu BH

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:To determine if prolactin levels are associated with glucose-insulin homeostasis in antipsychotic-treated patients with schizophrenia. METHOD:Prolactin levels and glucose homeostasis (quantified using oral glucose tolerance testing, insulin measurement, and homeostasis model assessment) were measured in 15 ...

journal_title：Journal of clinical psychopharmacology

authors： Howes OD,Smith S,Gaughran FP,Amiel SA,Murray RM,Pilowsky LS

更新日期：2006-12-01 00:00:00

abstract：:A double-blind, placebo-controlled trial was performed to determine the efficacy and tolerability of 8 weeks of treatment with risperidone in the management of 48 adolescent and adult patients with Tourette syndrome. Twenty-four patients were randomly assigned to treatment with risperidone in doses of 0.5 to 6.0 mg/da...

journal_title：Journal of clinical psychopharmacology

authors： Dion Y,Annable L,Sandor P,Chouinard G

更新日期：2002-02-01 00:00:00

abstract：:Weight gain is a problem commonly encountered with antipsychotic treatment and has become more apparent with increasing use of the newer atypical antipsychotics. The adipocyte-derived hormone, leptin, has been associated with body weight and energy homeostasis, and abnormal regulation of leptin could play a role in we...

journal_title：Journal of clinical psychopharmacology

authors： Zhang XY,Tan YL,Zhou DF,Haile CN,Cao LY,Xu Q,Shen Y,Kosten TA,Kosten TR

更新日期：2007-06-01 00:00:00

abstract：:Plasma and red blood cell levels of haloperidol, thioridazine, and thioridazine's main metabolite mesoridazine were measured in schizophrenic outpatients during treatment with fixed doses of haloperidol or thioridazine for several months. These drug levels were compared to those in schizophrenic inpatients treated wit...

journal_title：Journal of clinical psychopharmacology

authors： Shvartsburd A,Sajadi C,Morton V,Mirabi M,Gordon J,Smith RC

更新日期：1984-08-01 00:00:00

abstract：:Physician-rating scales remain the standard in antidepressant clinical trials. The current study aimed to examine the discrepancies between physician-rating scales and self-rating scales for symptoms and functioning, before and after treatment, in newly hospitalized patients. A total of 131 acutely ill inpatients with...

journal_title：Journal of clinical psychopharmacology

authors： Lin CH,Lu MJ,Wong J,Chen CC

更新日期：2014-12-01 00:00:00

abstract：:As many as 45% of patients with major depression also meet diagnostic criteria for bipolar (BP) II disorder. Although the use of a concurrent mood-stabilizing drug has been suggested in treating BP II depression, antidepressant monotherapy has received less attention. The efficacy and safety of venlafaxine were examin...

journal_title：Journal of clinical psychopharmacology

authors： Amsterdam J

更新日期：1998-10-01 00:00:00

abstract：:Fluoxetine, a selective serotonin reuptake inhibitor, is currently being evaluated as a potential treatment for cocaine abuse. This 4-week inpatient study evaluated the pharmacologic interaction between fluoxetine and cocaine in healthy adult male volunteers (N = 5) with histories of cocaine abuse. Oral capsules were ...

journal_title：Journal of clinical psychopharmacology

authors： Walsh SL,Preston KL,Sullivan JT,Fromme R,Bigelow GE

更新日期：1994-12-01 00:00:00

abstract：:Drug delivery systems capable of delivering free (unconjugated) curcuminoids is of great therapeutic significance, since the absorption of bioactive and permeable form plays a key factor in mediating the efficacy of a substance which undergoes rapid biotransformation. Considering the recent understanding on the relati...

journal_title：Journal of clinical psychopharmacology

authors： Pandaran Sudheeran S,Jacob D,Natinga Mulakal J,Gopinathan Nair G,Maliakel A,Maliakel B,Kuttan R,Im K

更新日期：2016-06-01 00:00:00

abstract：:Quetiapine (QTP) combined with lithium (Li) or divalproex (DVP) for the treatment of mania was evaluated in 2 double-blind, placebo-controlled studies. Patients were randomized to 3 or 6 weeks of treatment with QTP plus Li/DVP or placebo (PBO) plus Li/DVP. Quetiapine was dosed up to 800 mg/d; Li was dosed to achieve s...

journal_title：Journal of clinical psychopharmacology

authors： Yatham LN,Paulsson B,Mullen J,Vågerö AM

更新日期：2004-12-01 00:00:00

abstract：PURPOSE/BACKGROUND:The number of patients with acute synthetic cannabinoid intoxication (SCI) has increased in recent years although the prohibition of its legal sale and use in Turkey despite other countries allowing to some extent sale and use. The reported clinical findings of acute SCI are similar to the symptoms o...

journal_title：Journal of clinical psychopharmacology

authors： Altintop I

更新日期：2020-09-01 00:00:00

abstract：:Disordered water balance, or polydipsia, is an underassessed and underreported phenomenon present in the severely psychiatrically disabled population. Prevalence rates for polydipsia range from 6.2 to 20%. We followed up five male patients (mean age 43) with chronic schizophrenia who met the Kane criteria for being tr...

journal_title：Journal of clinical psychopharmacology

authors： Fuller MA,Jurjus G,Kwon K,Konicki PE,Jaskiw GE

更新日期：1996-08-01 00:00:00

abstract：PURPOSE:The aim of this article is to review the recent trials of α7 nicotinic acetylcholine receptor (α7 nAChR) agonists and positive allosteric modulators (PAMs) on the treatment of cognitive decline in schizophrenia. α7 Nicotinic acetylcholine receptor abnormalities in schizophrenia and clinical implications of α7 n...

journal_title：Journal of clinical psychopharmacology

authors： Jones C

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:This post hoc meta-analysis evaluated the efficacy and safety of desvenlafaxine 50 and 100 mg versus placebo across age groups and severity of depression at baseline in patients with major depressive disorder. METHODS:Data from placebo and desvenlafaxine 50-mg and 100-mg dose arms were pooled from 9 short-term...

journal_title：Journal of clinical psychopharmacology

authors： Mosca D,Zhang M,Prieto R,Boucher M

更新日期：2017-04-01 00:00:00

abstract：PURPOSE/BACKGROUND:Extensive research has been conducted comparing the metabolic characteristics of older second-generation antipsychotics (SGAs); minimal data exist comparing the long-term metabolic effects of SGAs approved in the last 10 years. METHODS/PROCEDURES:A retrospective chart review of patients treated with...

journal_title：Journal of clinical psychopharmacology

authors： Greger J,Aladeen T,Lewandowski E,Wojcik R,Westphal E,Rainka M,Capote H

更新日期：2021-01-01 00:00:00

abstract：:This investigation aimed to provide evidence on the lack of pharmacokinetic interaction of paroxetine (20 mg/d) and alprazolam (1 mg/d) in combined therapy. In addition, the central effects of both drugs when administered alone and in combination were assessed to rule out any relevant synergistic depressant central ef...

journal_title：Journal of clinical psychopharmacology

authors： Calvo G,García-Gea C,Luque A,Morte A,Dal-Ré R,Barbanoj M

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Craving, an urge or increased desire to take a drug, is part of a cluster of behavioral, cognitive, and physiological phenomena that can develop after substance use. Self-reported cravings for heroin and cocaine are compared in opioid dependent patients while receiving maintenance treatment with slow-release ...

journal_title：Journal of clinical psychopharmacology

authors： Falcato L,Beck T,Reimer J,Verthein U

更新日期：2015-04-01 00:00:00

abstract：:Olanzapine is an atypical antipsychotic effective in the treatment of schizophrenic patients. After a 2- to 9-day placebo lead-in, 79 inpatients with schizophrenia according to DSM-III-R criteria were placed on an olanzapine dosage of 10 mg/day or 1 mg/day for up to 6 weeks. Blood samples were obtained weekly during t...

journal_title：Journal of clinical psychopharmacology

authors： Perry PJ,Sanger T,Beasley C

更新日期：1997-12-01 00:00:00

abstract：:Newer atypical antipsychotics demonstrate superior effectiveness, with a diminished incidence of extrapyramidal side effects compared with older typical antipsychotics, but they have been associated with the development of obesity and new-onset diabetes. A small number of reports documenting modest hypertriglyceridemi...

journal_title：Journal of clinical psychopharmacology

authors： Meyer JM

更新日期：2001-08-01 00:00:00

abstract：:Quetiapine is an atypical antipsychotic that has sedative effects. In this retrospective study, indices of alcohol use were compared for alcohol-dependent subjects who either were (n = 30) or were not (n = 20) treated with quetiapine (25 to 200 mg nightly) for disturbed sleep. Indices examined included total days of a...

journal_title：Journal of clinical psychopharmacology

authors： Monnelly EP,Ciraulo DA,Knapp C,LoCastro J,Sepulveda I

更新日期：2004-10-01 00:00:00

abstract：:The study presented here compared the acute performance-impairing, subject-rated, and observer-rated effects of quazepam (15, 30, and 45 mg), triazolam (0.1875, 0.375, and 0.5625 mg), zolpidem (7.5, 15, and 22.5 mg), and placebo in nine healthy, non-drug-abusing humans. Quazepam, a trifluoroethylbenzodiazepine, was ch...

journal_title：Journal of clinical psychopharmacology

authors： Rush CR,Armstrong DL,Ali JA,Pazzaglia PJ

更新日期：1998-04-01 00:00:00

abstract：:A double-blind controlled study comparing the effects of bupropion to doxepin in outpatients with primary depression was conducted to evaluate efficacy and safety differences between the two drugs. Following a 7-day placebo washout period, patients could be treated for up to 13 weeks on either treatment. Antidepressan...

journal_title：Journal of clinical psychopharmacology

authors： Feighner J,Hendrickson G,Miller L,Stern W

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to use a visual analog scale (VAS) longitudinally measuring somnolence severity in patients with bipolar disorder. METHODS:A data set of patients with bipolar spectrum disorders who were randomized to lithium or quetiapine-IR for 16 weeks was used. The somnolence severity was measur...

journal_title：Journal of clinical psychopharmacology

authors： Gao K,Su M,Ganocy SJ,Goto T,Yuan C,Fang F,Conroy C,Brownrigg B,Serrano MB,Calabrese JR

更新日期：2019-05-01 00:00:00