Cardiovascular and catecholamine response to surgery in brain-dead organ donors.

Abstract:

:Eleven brain-dead organ donors were studied during surgery. Plasma levels of adrenaline and noradrenaline were measured before and after skin incision, upon sternotomy and 15, 30 and 45 min thereafter. Haemodynamic changes were measured continuously throughout the observation period. Blood pressure and heart rate increased after skin incision, remained high at sternotomy then decreased towards the end of the observation period in six of the 11 patients. Plasma catecholamines increased promptly with the onset of surgical stimuli. We conclude that surgical stress can evoke an excessive rise of plasma adrenaline and noradrenaline and thus could impair allograft function.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Fitzgerald RD,Dechtyar I,Templ E,Fridrich P,Lackner FX

doi

10.1111/j.1365-2044.1995.tb05989.x

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

388-92

issue

5

eissn

0003-2409

issn

1365-2044

journal_volume

50

pub_type

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