Induction of general anaesthesia by effect-site target-controlled infusion of propofol: influence of pharmacokinetic model and ke0 value.

abstract：:The position of doctors with domestic commitments (DDCs) at present training in the specialty of anaesthesia in the British National Health Service is considered and proposals are made for their future employment in career grades. ...

journal_title：Anaesthesia

authors： Edmonds-Seal J,McNeilly RH

更新日期：1981-11-01 00:00:00

abstract：:Using the Nottingham Physiology Simulator, we investigated the effects on pre-oxygenation and apnoea during rapid sequence induction of labour, obesity, sepsis, pre-eclampsia, maternal haemorrhage and multiple pregnancy in term pregnancy. Pre-oxygenation with 100% oxygen was followed by simulated rapid sequence induct...

journal_title：Anaesthesia

authors： McClelland SH,Bogod DG,Hardman JG

更新日期：2009-04-01 00:00:00

abstract：:Twenty patients who received electroconvulsive therapy were anaesthetised with either propofol or methohexitone in a randomised crossover study. Recovery times were similar but patients who received propofol tended to be orientated sooner. The decrease in arterial blood pressure after induction was greater with propof...

journal_title：Anaesthesia

authors： Rouse EC

更新日期：1988-03-01 00:00:00

abstract：:We developed a closed-loop system to control the depth of anaesthesia and neuromuscular blockade using the bispectral index and the electromyogram simultaneously and evaluated the clinical performance of this combined system for general anaesthesia. Twenty-two adult patients were included in this study. Anaesthesia wa...

journal_title：Anaesthesia

authors： Janda M,Simanski O,Bajorat J,Pohl B,Noeldge-Schomburg GF,Hofmockel R

更新日期：2011-12-01 00:00:00

abstract：:The performance of the occlusion and Pethick tests in detecting faulty inner tubes in co-axial circle and Bain systems was compared. Twelve co-axial circle and 12 Bain anaesthetic breathing systems were tested using the occlusion and the Pethick tests. For each system, three tubes were intact, and the remaining nine h...

journal_title：Anaesthesia

authors： Szypula KA,Ip JK,Bogod D,Yentis SM

更新日期：2008-10-01 00:00:00

abstract：:We systematically reviewed randomised controlled trials of the i-gel® vs different types of laryngeal mask airway in children. We included nine studies. There was no evidence for differences in: rate of insertion at first attempt; insertion time; ease of insertion; or gastric tube insertion. The mean (95% CI) orophary...

journal_title：Anaesthesia

authors： Choi GJ,Kang H,Baek CW,Jung YH,Woo YC,Cha YJ

更新日期：2014-11-01 00:00:00

abstract：SUMMARY:In a randomised, double-blinded study, we compared boluses of phenylephrine 100 microg with ephedrine 10 mg for treating hypotension (systolic blood pressure < 100 mmHg) in 204 patients having non-elective Caesarean section under spinal anaesthesia. Umbilical arterial (UA) and venous (UV) pH and base excess wer...

journal_title：Anaesthesia

authors： Ngan Kee WD,Khaw KS,Lau TK,Ng FF,Chui K,Ng KL

更新日期：2008-12-01 00:00:00

abstract：:The aim of this study was to determine whether permitting women in labour to eat a light diet would: (i) alter their metabolic profile, (ii) influence the outcome of labour, and (iii) increase residual gastric volume and consequent risk of pulmonary aspiration. Women were randomised to receive either a light diet (eat...

journal_title：Anaesthesia

authors： Scrutton MJ,Metcalfe GA,Lowy C,Seed PT,O'Sullivan G

更新日期：1999-04-01 00:00:00

abstract：:Malignant obstructive jaundice is associated with poor aerobic capacity. We measured oxygen consumption and oxygen extraction (arterial-venous oxygen content) in the legs of nine patients during cardiopulmonary exercise testing before pancreaticoduodenectomy. The median (IQR [range]) peak oxygen consumption was 67 (49...

journal_title：Anaesthesia

authors： Junejo MA,Siriwardena AK,Parker MJ

更新日期：2014-01-01 00:00:00

abstract：:Epidural sufentanil 50 micrograms was compared with intramuscular buprenorphine 0.3 mg for postoperative pain relief. Patients were assigned randomly to one of two treatment groups and received both an intramuscular and epidural injection, one of which was a placebo. Onset of pain relief was faster and quality of anal...

journal_title：Anaesthesia

authors： Donadoni R,Rolly G

更新日期：1987-11-01 00:00:00

abstract：:We assessed the resistance to air flow in four commonly used air inlets. The Avon A81 and Codan air inlets provide the least resistance to flow, followed by the Baxter CO413 and lastly the Braun air inlet. The presence of a valve confers an advantage when rapid infusion of fluid is attempted. The valve in the Codan ai...

journal_title：Anaesthesia

authors： Thorpe CM,Scott DH

更新日期：1994-07-01 00:00:00

abstract：:Opioid induced respiratory depression is potentially fatal. The aim of this study was to validate a monitoring system that could be used to assess respiratory depression in postoperative patients. The hypercapnic ventilatory response was estimated non-invasively in 12 volunteers. In two steps, we tested a system which...

journal_title：Anaesthesia

authors： Pattinson KT,Bowes M,Wise RG,Parkes MJ,Morrell MJ

更新日期：2005-05-01 00:00:00

abstract：:Capnography (ETCO2 ) is routinely used as a non-invasive estimate of arterial carbon dioxide (PaCO2 ) levels in order to modify ventilatory settings, whereby it is assumed that there is a positive gap between PaCO2 and ETCO2 of approximately 0.5 kPa. However, negative values (ETCO2 > PaCO2 ) can be observed. We retros...

journal_title：Anaesthesia

authors： Onodi C,Bühler PK,Thomas J,Schmitz A,Weiss M

更新日期：2017-11-01 00:00:00

abstract：:Various methods by which the Cape Minor ventilator may be used in the circle absorber system are described and the problems of the circuits described are considered. A new valve system is described which overcomes most of the problems encountered with other circuits. The economic advantages of an inexpensive ventilato...

journal_title：Anaesthesia

authors： James MF

更新日期：1978-11-01 00:00:00

abstract：:The admission of patients with acquired immune deficiency syndrome (AIDS) to intensive care units in the United Kingdom was surveyed in January 1986. Ninety-three intensive care units completed the questionnaire. Thirty-two patients had been admitted to 12 units up to that time. Twenty-five (78%) of these patients had...

journal_title：Anaesthesia

authors： Deam R,Kimberley AP,Anderson M,Soni N

更新日期：1988-02-01 00:00:00

abstract：:This study of 100 day case patients having cataract surgery under local anaesthesia compared patient acceptance of two peri-ocular techniques; a transcutaneous method and a transconjunctival method. A significant difference was found in relation to the pain felt on injection such that all peri-ocular blocks at our uni...

journal_title：Anaesthesia

authors： Sweeney EJ,Barber K,Prosser JA

更新日期：1993-04-01 00:00:00

abstract：:The C-MAC comprises a Macintosh blade connected to a video unit. The familiarity of the Macintosh blade, and the ability to use the C-MAC as a direct or indirect laryngoscope, may be advantageous. We wished to compare the C-MAC with Macintosh, Glidescope and Airtraq laryngoscopes in easy and simulated difficult laryng...

journal_title：Anaesthesia

authors： McElwain J,Malik MA,Harte BH,Flynn NM,Laffey JG

更新日期：2010-05-01 00:00:00

abstract：:The use of intra-operative Doppler oesophageal probes provides continuous monitoring of cardiac output. This enables optimisation of intravascular volume and tissue perfusion in major abdominal surgery, which is thought to reduce postoperative complications and shorten hospital stay. Medline and EMBASE were searched u...

journal_title：Anaesthesia

authors： Abbas SM,Hill AG

更新日期：2008-01-01 00:00:00

abstract：:A randomised, double-blind placebo controlled study was undertaken to assess the analgesic efficacy of diclofenac. Following major abdominal surgery and 12 hours later, patients received either placebo or diclofenac 75 mg intramuscularly and their cumulative morphine requirements administered by a patient-controlled s...

journal_title：Anaesthesia

authors： Hodsman NB,Burns J,Blyth A,Kenny GN,McArdle CS,Rotman H

更新日期：1987-09-01 00:00:00

abstract：:Oxygen concentrations were measured at 12 points around a cardiopulmonary resuscitation practice mannequin following simulated ventilation with a self-inflating bag, a 'Waters' bag and a ventilator to determine whether increased oxygen concentrations may contribute to the risk of combustion from arcing defibrillator p...

journal_title：Anaesthesia

authors： Robertshaw H,McAnulty G

更新日期：1998-07-01 00:00:00

abstract：:This review summarises the physiological and pharmacological effects of the anabolic steroids used to enhance performance in sports. The anabolic steroids promote muscle growth and protein synthesis. Side-effects of anabolic steroids include cardiomyopathy, atherosclerosis, hypercoagulopathy, hepatic dysfunction, and ...

journal_title：Anaesthesia

authors： Kam PC,Yarrow M

更新日期：2005-07-01 00:00:00

abstract：:Intravenous lipid emulsion is established therapy for bupivacaine induced cardiotoxicity. The benefit of combined hypertonic saline and lipid treatment is unexplored. In this experiment, sedated rabbits were resuscitated from bupivacaine-induced asystole with intravenous lipid according to the Association of Anaesthet...

journal_title：Anaesthesia

authors： Cave G,Harvey M,Prince G,Lahner D,Desmet J

更新日期：2010-08-01 00:00:00

abstract：:We have previously demonstrated that the peri-operative measurement of increased serum concentrations of the cardiac markers troponins I and T and creatine kinase-MB can be predictors of major cardiovascular outcomes (including cardiac death) at 3 months after surgery. In the present study, we have followed the postop...

journal_title：Anaesthesia

authors： Higham H,Sear JW,Sear YM,Kemp M,Hooper RJ,Foex P

更新日期：2004-04-01 00:00:00

abstract：:A new approach to the internal jugular vein is described which keeps the head and neck in the neutral position and uses bony and cartilaginous landmarks for guidelines. Venous puncture is made along an axial line drawn superiorly from the lateral edge of the bony depression caused by the insertion of the sternocleidom...

journal_title：Anaesthesia

authors： Willeford KL,Reitan JA

更新日期：1994-03-01 00:00:00

abstract：:The cardiovascular effects of 20 ml 0.75% bupivacaine with adrenaline 5 micrograms/ml injected epidurally were compared with those of 20 ml 0.75% ropivacaine with adrenaline. Cardiovascular measurements were performed with a transthoracic electrical bioimpedance monitor. The maximum mean arterial blood pressure decrea...

journal_title：Anaesthesia

authors： Kerkkamp HE,Gielen MJ

更新日期：1991-05-01 00:00:00

abstract：:The efficacy of thoracic epidural sufentanil 50 micrograms was compared with lumbar epidural sufentanil 50 micrograms in 30 patients (n = 15 in each group) undergoing lateral thoracotomy. Sufentanil was administered epidurally after induction of anaesthesia with sufentanil 1 microgram.kg-1 and thiopentone 2-5 mg.kg-1 ...

journal_title：Anaesthesia

authors： Haak-van der Lely F,van Kleef JW,Burm AG,Bovill JG

更新日期：1994-02-01 00:00:00

abstract：:We report the findings of a study on exposure of operating room staff to sevoflurane, halothane and nitrous oxide during induction and maintenance of anaesthesia in children. Concentrations of anaesthetic agents in the operating theatre were measured directly by highly sensitive, photoacoustic infrared spectrometer du...

journal_title：Anaesthesia

authors： Hoerauf K,Funk W,Harth M,Hobbhahn J

更新日期：1997-03-01 00:00:00

abstract：:The ultrasonic cardiac output monitor is a non-invasive, continuous-wave Doppler monitor that can be used to measure cardiac output. Its accuracy and precision in peri-operative and critical care has been assessed with varied results. We conducted a meta-analysis to calculate a pooled mean bias, precision and percenta...

journal_title：Anaesthesia

authors： Chong SW,Peyton PJ

更新日期：2012-11-01 00:00:00

abstract：:We tried to determine if a blood conservation pressure transducer system reduced blood transfusions, increased haemoglobin concentration or reduced line infections in critically ill patients. One hundred patients were randomly allocated to conventional or blood conserving systems attached to systemic and pulmonary art...

journal_title：Anaesthesia

authors： Thorpe S,Thomas AN

更新日期：2000-01-01 00:00:00

abstract：:A randomised, double-blind comparison of the efficacy, duration of action and side effects of two analgesic regimens following elective epidural Caesarean section is described. Patients received epidural diamorphine 3 mg or intramuscular morphine 10 mg in the immediate postoperative period. Time to next analgesia was ...

journal_title：Anaesthesia

authors： Stevens JD,Braithwaite P,Corke CF,Madej TH,Wheatley RG

更新日期：1991-04-01 00:00:00