Mitral valve prolapse.

abstract：BACKGROUND:Transfer of the coronary arteries is a crucial step during the arterial switch operation (ASO) for transposition of the great arteries. This retrospective study aims to assess the incidence and risk factors of coronary events after ASO and sensitivity of noninvasive tests in the diagnosis of the coronary obs...

journal_title：Circulation

authors： Legendre A,Losay J,Touchot-Koné A,Serraf A,Belli E,Piot JD,Lambert V,Capderou A,Planche C

更新日期：2003-09-09 00:00:00

abstract：BACKGROUND:Because pulmonary artery size is considered by most investigators to be a major prognosticator of outcome in patients undergoing staged Fontan reconstruction, the objective of the present study was to determine the efficacy of noninvasive measures in determining pulmonary artery size. METHODS AND RESULTS:Th...

journal_title：Circulation

authors： Fogel MA,Donofrio MT,Ramaciotti C,Hubbard AM,Weinberg PM

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Abnormal vascular reactivity represents a fundamental disturbance in vascular biology with the development of atherosclerosis. Because endothelial vasodilator function plays a pivotal role in controlling vasomotor tone, we hypothesized that atherosclerotic wall thickening might directly interfere with defici...

journal_title：Circulation

authors： Zeiher AM,Schächlinger V,Hohnloser SH,Saurbier B,Just H

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Hemodynamic stability after Norwood palliation often requires manipulation of pulmonary vascular resistance to alter the pulmonary-to-systemic blood flow ratio (Qp:Qs). Qp:Qs is often estimated from arterial saturation (SaO2), a practice based on 2 untested assumptions: constant systemic arteriovenous O2 dif...

journal_title：Circulation

authors： Taeed R,Schwartz SM,Pearl JM,Raake JL,Beekman RH 3rd,Manning PB,Nelson DP

更新日期：2001-06-05 00:00:00

abstract：BACKGROUND:The heart can synthesize epinephrine. Homogenates of rat heart, which contain the enzymes phenylethanolamine N-methyltransferase (PNMT) and nonspecific N-methyltransferase (NMT), methylate norepinephrine to form epinephrine. The cardiac atrium contains primarily PNMT and the cardiac ventricle contains both P...

journal_title：Circulation

authors： Kennedy B,Ziegler MG

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Proliferation of smooth muscle cells (SMCs) plays an important role in vascular pathobiology, being involved in the development of coronary restenosis and atherosclerosis. The activation of nuclear proto-oncogenes appears to be a final common pathway onto which various mitogenic signals coverage. Accordingly...

journal_title：Circulation

authors： Shi Y,Hutchinson HG,Hall DJ,Zalewski A

更新日期：1993-09-01 00:00:00

abstract：:Composite graft replacement of the ascending aorta and aortic valve was performed in 78 patients over an 8 1/2-year period. Degenerative lesions of the aortic root in Marfan's syndrome (annuloaortic ectasia) was the indication for operation in 56 cases; the other 22 patients had other causes of aortic root dilatation ...

journal_title：Circulation

authors： Donaldson RM,Ross DN

更新日期：1982-08-01 00:00:00

abstract：:The automatic implantable cardioverter-defibrillator (ICD) is highly effective in reducing sudden death rates in patients with life-threatening ventricular tachyarrhythmias. However, the magnitude of the ability of the ICD to improve overall survival is less certain. Data supporting the contention that the ICD prolong...

journal_title：Circulation

authors： Sweeney MO,Ruskin JN

更新日期：1994-04-01 00:00:00

abstract：:A 28-year-old female undergoing elective total hip replacement experienced an anaphylactic reaction to succinylcholine. Hemodynamics, plasma histamine and catecholamines were measured. The tachycardia experienced during the reaction appeared to be secondary to the sympathoadrenal response rather than a direct chronotr...

journal_title：Circulation

authors： Moss J,Fahmy NR,Sunder N,Beaven MA

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:In heart failure, sarcoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA2a) activity is decreased, resulting in abnormal calcium handling and contractile dysfunction. We have previously shown that increasing SERCA2a expression by gene transfer improves ventricular function in a rat model of heart failure created b...

journal_title：Circulation

authors： del Monte F,Williams E,Lebeche D,Schmidt U,Rosenzweig A,Gwathmey JK,Lewandowski ED,Hajjar RJ

更新日期：2001-09-18 00:00:00

abstract：:Carotid artery stenting, compared with carotid endarterectomy, is emerging as an effective and less invasive method of revascularization for extracranial carotid artery stenosis. Carotid stenting is established as the treatment of choice for certain high-risk patient subsets, and ongoing clinical trials are evaluating...

journal_title：Circulation

authors： Roubin GS,Iyer S,Halkin A,Vitek J,Brennan C

更新日期：2006-04-25 00:00:00

abstract：:Under the auspices of the Agency for Healthcare Research and Quality, the United States Preventive Services Task Force (USPSTF) recently released an update to its 1996 Peripheral Arterial Disease (PAD) Screening Recommendation Statement. The USPSTF recommended against PAD screening, giving the practice a "D" level rec...

journal_title：Circulation

authors： Beckman JA,Jaff MR,Creager MA

更新日期：2006-08-22 00:00:00

abstract：:A clinical study was conducted to evaluate the efficacy and safety of percutaneous coronary excimer laser angioplasty in 60 patients with coronary artery disease. Forty-nine patients had stable exertional angina, and 11 patients had unstable angina despite medical therapy. A novel 1.4-mm diameter catheter with 20 quar...

journal_title：Circulation

authors： Karsch KR,Haase KK,Voelker W,Baumbach A,Mauser M,Seipel L

更新日期：1990-06-01 00:00:00

abstract：:In a placebo-controlled, randomized, cross-over, double-blind study of 12 patients with stable exertional angina, we measured at rest and during bicycle exercise the effects of 20 mg of nifedipine administered sublingually on hemodynamics and systemic and regional oxygen extraction and metabolism. Nifedipine decreased...

journal_title：Circulation

authors： Choong CY,Roubin GS,Shen WF,Harris PJ,Kelly DT

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Recent data suggest that the Berlin Heart EXCOR Pediatric ventricular assist device is superior to extracorporeal membrane oxygenation for bridge to heart transplantation. Published data are limited to 1 in 4 children who received the device as part of the US clinical trial. We analyzed outcomes for all US c...

journal_title：Circulation

authors： Almond CS,Morales DL,Blackstone EH,Turrentine MW,Imamura M,Massicotte MP,Jordan LC,Devaney EJ,Ravishankar C,Kanter KR,Holman W,Kroslowitz R,Tjossem C,Thuita L,Cohen GA,Buchholz H,St Louis JD,Nguyen K,Niebler RA,Walt

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:Pharmacological ventricular rate control is an acceptable atrial fibrillation (AF) therapy limited by systemic toxicity. We postulate that focal catheter-based drug delivery into the atrioventricular nodal (AVN) region may effectively control ventricular rate during AF without systemic toxicity. This study e...

journal_title：Circulation

authors： Sigg DC,Hiniduma-Lokuge P,Coles JA Jr,Falkner P,Rose R,Urban JF,Ujhelyi MR

更新日期：2006-05-23 00:00:00

abstract：:The aim of this policy statement is to provide a comprehensive review of the scientific evidence evaluating the use of telemedicine in cardiovascular and stroke care and to provide consensus policy suggestions. We evaluate the effectiveness of telehealth in advancing healthcare quality, identify legal and regulatory b...

journal_title：Circulation

authors： Schwamm LH,Chumbler N,Brown E,Fonarow GC,Berube D,Nystrom K,Suter R,Zavala M,Polsky D,Radhakrishnan K,Lacktman N,Horton K,Malcarney MB,Halamka J,Tiner AC,American Heart Association Advocacy Coordinating Committee.

更新日期：2017-02-14 00:00:00

abstract：:Contrast M-mode and two-dimensional ultrasonography of the inferior vena cava were performed in 65 patients with various acquired and congenital cardiac disorders. After saline was injected into a peripheral arm vein, the inferior vena cava was visualized by both methods in 60 patients (92%). The M-mode approach was b...

journal_title：Circulation

authors： Wise NK,Myers S,Fraker TD,Stewart JA,Kisslo JA

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:The influence of changes in heart rate on myocardial contractility (the force-frequency effect) differs under various experimental conditions, including the anesthetized versus the conscious state. METHODS AND RESULTS:To assess the influence of beta-adrenergic stimulation on force-frequency effects on myoca...

journal_title：Circulation

authors： Kambayashi M,Miura T,Oh BH,Rockman HA,Murata K,Ross J Jr

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Ventricular tachyarrhythmias are the major clinical manifestation of arrhythmogenic right ventricular disease. Although antiarrhythmic therapy has been widely advocated, there is only limited information available on the efficacy of antiarrhythmic drugs in these patients. METHODS AND RESULTS:The short- and ...

journal_title：Circulation

authors： Wichter T,Borggrefe M,Haverkamp W,Chen X,Breithardt G

更新日期：1992-07-01 00:00:00

abstract：:Because acute segmental wall motion abnormalities (SWMAs) of the left ventricle are highly sensitive and specific indicators of myocardial ischemia, this study compared the incidence and significance of ischemia, as detected by two-dimensional transesophageal echocardiography and surface electrocardiography, during an...

journal_title：Circulation

authors： Smith JS,Cahalan MK,Benefiel DJ,Byrd BF,Lurz FW,Shapiro WA,Roizen MF,Bouchard A,Schiller NB

更新日期：1985-11-01 00:00:00

abstract：:To evaluate possible occult myocardial disease in 18 patients whose only major manifestation of heart disease was spontaneous ventricular tachycardia or fibrillation, right ventricular endomyocardial biopsies were performed. None of the patients had symptoms of ischemic or congestive heart disease, and at catheterizat...

journal_title：Circulation

authors： Strain JE,Grose RM,Factor SM,Fisher JD

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:While previous clinical studies have shown a possible beneficial effect of the reperfusion performed at a relatively late phase of acute myocardial infarction ("late reperfusion") in preventing left ventricular enlargement, the mechanism has not been clarified. METHODS AND RESULTS:Of 89 patients with an ini...

journal_title：Circulation

authors： Hirayama A,Adachi T,Asada S,Mishima M,Nanto S,Kusuoka H,Yamamoto K,Matsumura Y,Hori M,Inoue M

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Short-term (<30 day) mortality after Q-wave myocardial infarction (MI) has declined over the decades, but it is unclear if rates of long-term sequelae after Q-wave MI have improved. METHODS AND RESULTS:In 546 Framingham Heart Study subjects (388 men with a mean age of 60 years; 158 women with a mean age of ...

journal_title：Circulation

authors： Guidry UC,Evans JC,Larson MG,Wilson PW,Murabito JM,Levy D

更新日期：1999-11-16 00:00:00

abstract：:The elimination of specific dietary cholesterol target recommendations in recent guidelines has raised questions about its role with respect to cardiovascular disease. This advisory was developed after a review of human studies on the relationship of dietary cholesterol with blood lipids, lipoproteins, and cardiovascu...

journal_title：Circulation

authors： Carson JAS,Lichtenstein AH,Anderson CAM,Appel LJ,Kris-Etherton PM,Meyer KA,Petersen K,Polonsky T,Van Horn L,American Heart Association Nutrition Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Arteriosclero

更新日期：2020-01-21 00:00:00

abstract：:A genetic-epidemiologic study was undertaken of a white Colorado population of 207 patients who had a myocardial infarction before age 55 years. Nineteen independent variables were compared between the 207 cases and 621 controls, matched 3:1. The highest risk ratios were associated with a positive family history for i...

journal_title：Circulation

authors： Nora JJ,Lortscher RH,Spangler RD,Nora AH,Kimberling WJ

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Altered composition of the gut microbiota is involved in both the onset and progression of obesity and diabetes mellitus. However, the link between gut microbiota and obesity-related cardiovascular complications has not been explored. The present study was designed to investigate the role of Akkermansia muci...

journal_title：Circulation

authors： Li J,Lin S,Vanhoutte PM,Woo CW,Xu A

更新日期：2016-06-14 00:00:00

abstract：BACKGROUND:Whether reperfusion can cause necrosis of previously viable myocytes (lethal reperfusion injury) remains controversial. Numerous studies examined the ability of various agents to prevent or limit reperfusion injury, but the results were contradictory. In a single-canine-heart model of ischemia-reperfusion, w...

journal_title：Circulation

authors： Zahger D,Yano J,Chaux A,Fishbein MC,Ganz W

更新日期：1995-06-15 00:00:00

abstract：BACKGROUND:A low ankle-arm index (AAI) is a strong predictor of mortality and cardiovascular events. A high AAI also appears to be associated with higher mortality risk in select populations. However, mortality and cardiovascular risk across the AAI spectrum have not been described in a more broadly defined population....

journal_title：Circulation

authors： O'Hare AM,Katz R,Shlipak MG,Cushman M,Newman AB

更新日期：2006-01-24 00:00:00

abstract：:This study explored the association between sodium excretion and blood pressure (BP). A new method was used to minimize the measurement error introduced by the large intrinsic variability of 24-hour sodium excretion. The ratio of intra- to interindividual variation was used to estimate the number of measurements neede...

journal_title：Circulation

authors： Cooper R,Soltero I,Liu K,Berkson D,Levinson S,Stamler J

更新日期：1980-07-01 00:00:00