Abstract：
:We evaluated two topical cyclo-oxygenase inhibitors (COIs), 0.03% flurbiprofen and 1% indomethacin, for their ability to prevent pseudophakic cystoid macular edema (CME). The study was a randomized, double-masked, vehicle-controlled, parallel group, clinical trial for six months at eight sites in Canada and two in Germany. The study population consisted of 681 patients who had extracapsular cataract extraction and posterior chamber lens implantation. Flurbiprofen, indomethacin, or the vehicle was instilled into the eye four times daily for two days preoperatively and three months postoperatively. Results were measured by angiographic and clinical CME at visit 5 (day 21-60) and visit 7 (day 121-240) and by contrast sensitivity and Snellen visual acuity at all five postoperative visits. At visit 5, the incidence of angiographic CME was comparable in the two COI treatment groups (16.8% flurbiprofen, 12.4% indomethacin) and was significantly lower than in the vehicle group (32.2%). The incidence of clinical CME was also significantly lower in the COI-treated groups (10.7% flurbiprofen, 9.6% indomethacin) than in the vehicle group (21.9%). By visit 7, the incidence of angiographic CME had declined to between 4% and 8% and the incidence of clinical CME was less than 2% in all three groups. At visit 5, contrast sensitivity scores were significantly worse in vehicle-treated patients with angiographic CME than in those without CME, and Snellen visual acuity was one line worse in patients with CME. Flurbiprofen-treated patients achieved good Snellen visual acuity (better than 20/40) sooner than vehicle-treated patients.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Solomon LDdoi
10.1016/s0886-3350(13)80484-1subject
Has Abstractpub_date
1995-01-01 00:00:00pages
73-81issue
1eissn
0886-3350issn
1873-4502pii
S0886-3350(13)80484-1journal_volume
21pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract：PURPOSE:To evaluate and compare the tear-film dynamics in normal eyes and in eyes with mild dry-eye symptoms using a new noninvasive optical method based on a double-pass instrument. SETTING:Hospital Universitario Virgen de la Arrixaca, Murcia, Spain. DESIGN:Evaluation of diagnostic test or technology. METHODS:Dynam...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.03.036
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:To investigate the magnitude of postoperative astigmatism in children having cataract extraction with intraocular lens (IOL) implantation through a 3.0 mm superior clear corneal incision. SETTING:Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA. METHODS:This retro...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2004.01.019
更新日期：2004-09-01 00:00:00
abstract：PURPOSE:To evaluate the results of the first blue light-filtering photochromic intraocular lens (IOL) and compare them with those of a regular yellow blue light-filtering IOL and a clear ultraviolet-filtering IOL in human eyes under various lighting conditions. SETTING:Beijing Tongren Eye Center, Beijing Tongren Hospi...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2010.07.024
更新日期：2010-12-01 00:00:00
abstract：:After the ultrasonic tip is introduced into the highly myopic eye and inflow is activated, the anterior chamber deepens, the lens-iris diaphragm is displaced posteriorly, the iris becomes concave, and the pupil dilates from the weight of the water column above the eye. We define a known but undescribed syndrome--the l...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80043-0
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:To compare the efficacy of heparin-surface-modified (HSM), poly(methyl methacrylate) (PMMA) posterior chamber intraocular lenses (IOLs) with that of unmodified PMMA IOLs in reducing postoperative complications caused by inflammatory reactions after extracapsular cataract extraction in an Asian population. SETT...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0886-3350(96)80170-2
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To compare the outcomes of mechanical and femtosecond laser-assisted tunnel creation for intrastromal corneal ring segment (ICRS) implantation in eyes with keratoconus. SETTING:Kartal Training and Research Hospital, Istanbul, Turkey. METHODS:In this prospective study, consecutive eyes with keratoconus were ra...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2010.04.028
更新日期：2010-09-01 00:00:00
abstract：PURPOSE:To evaluate whether intracameral triamcinolone has an effect on anterior segment inflammation and visual axis obscuration after pediatric cataract surgery with intraocular (IOL) implantation. SETTING:Iladevi Cataract and IOL Research Institute, Ahmedabad, India. METHODS:This retrospective age-matched case-con...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.03.040
更新日期：2010-09-01 00:00:00
abstract：UNLABELLED:A 22-year-old white man presented with photopsia of 3-year duration despite a corrected distance visual acuity of 20/20 in both eyes. Ophthalmic examination revealed multiple irregularly shaped white cortical opacifications of the lens in both eyes but no other significant ocular findings. One year after the...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.06.007
更新日期：2016-07-01 00:00:00
abstract：PURPOSE:To compare the shape and volume of the lenticules of corneal tissue ablated for the correction of spherical, cylindrical, and spherocylindrical refractive errors using Boolean operations of theoretical 3-dimensional (3-D) surfaces. SETTING:Department of Ophthalmology, Rothschild Foundation, Paris, France. MET...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(02)01379-2
更新日期：2002-11-01 00:00:00
abstract：:Phakic intraocular lens (IOL) implantation is an increasingly popular option in surgical correction of refractive error. To date, reports of long-term morbidity are infrequent in the literature. We encountered 3 patients who experienced corneal decompensation and cataract progression following angle-fixated anterior c...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.04.031
更新日期：2005-11-01 00:00:00
abstract：PURPOSE:To compare the visual acuity outcomes and the ocular and intraocular optical quality in patients with a monofocal intraocular lens (IOL) or a new-generation single-optic accommodating IOL. SETTING:Vissum Corporation, Alicante, Spain. DESIGN:Comparative case series. METHODS:Consecutive eyes of bilateral catar...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.04.040
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To compare the centration and fixation of silicone plate-haptic intraocular lenses (IOLs) with different-sized positioning holes. SETTING:Eye Clinic of the Johannes Gutenberg-University Mainz, Mainz, Germany. METHODS:In a prospective randomized study, 51 Chiroflex C10 and 56 Chiroflex C11 IOLs were implanted ...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(00)00496-x
更新日期：2000-12-01 00:00:00
abstract：PURPOSE:To determine and compare the amount of apoptosis and changes in rabbit corneal endothelial cell morphology after intracameral administration of different anesthetic agents. SETTING:Department of Ophthalmology, Baskent University Medical Faculty, Ankara, Turkey. METHODS:Right eyes of 64 Vienna white rabbits we...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.12.016
更新日期：2009-04-01 00:00:00
abstract：:In eyes with low scleral rigidity, penetrating keratoplasty (PKP) is a high-risk procedure because forward movement of the lens-iris diaphragm can result in prolapse of intraocular contents, expulsive choroidal hemorrhage, and damage to the crystalline lens. We developed a method for safer PKP in eyes with low scleral...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(99)00071-1
更新日期：1999-07-01 00:00:00
abstract：:Subepithelial fibrosis in the area of peripheral suture placement is an often overlooked phenomenon of healing following uneventful penetrating keratoplasty surgery. Three affected cornea transplant patients whose sutures had been removed were studied using videophotokeratoscopy before and after stripping of the subep...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80282-3
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of photorefractive keratectomy (PRK) with intraoperative application of mitomycin-C (MMC). SETTING:Yonsei Eye Center, Seoul, South Korea. METHODS:This retrospective noncomparative case series included 536 patients (1011 eyes) who had had PRK with intraoperative application ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.05.027
更新日期：2005-12-01 00:00:00
abstract：PURPOSE:To estimate the ability of the Ocular Response Analyzer parameters to aid in the diagnosis of keratoconus in pre-laser in situ keratomileusis (LASIK) patients. SETTING:Department of Ophthalmology, Bordeaux 2 University, Bordeaux Cedex, France. DESIGN:Evaluation of diagnostic test. METHODS:This study compared...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.06.029
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:To compare the outcomes of combined cataract surgery with trabecular microbypass stents and ab interno trabeculotomy in patients with open-angle glaucoma. SETTING:University of Toronto, Toronto, Ontario, and University of Montreal, Montreal, Quebec, Canada, and Glaucoma Associates of Texas, Dallas, Texas, USA....
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.12.061
更新日期：2015-08-01 00:00:00
abstract：:A 25-year-old woman with moderate myopia presented for refractive surgery. Bilateral femtosecond laser-assisted small-incision lenticule extraction (SMILE) was scheduled and her right eye was completed smoothly. However, during the lenticule cutting of her left eye, a large inferior black area was noted. The operation...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000185
更新日期：2020-06-01 00:00:00
abstract：:To describe the successful treatment of epithelial ingrowth using combined surgical excision with intracameral adjuvant 5-fluorouracil (5-FU) followed by Descemet-stripping automated endothelial keratoplasty (DSAEK). A 71-year-old man presented with epithelial ingrowth after clear corneal phacoemulsification. He under...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2018.12.030
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To determine whether preoperative assessment of posterior capsule integrity using anterior segment optical coherence tomography (AS-OCT) can predict posterior capsule dehiscence in patients with posterior polar cataract having phacoemulsification. SETTING:Aravind Eye Hospital and Postgraduate Institute of Opht...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2018.07.056
更新日期：2018-12-01 00:00:00
abstract：:Multifocal intraocular lenses (MIOLs) have been designed to provide better uncorrected near visual acuity than monofocal IOLs. However, the increase in depth of focus is combined with a significant decrease in contrast sensitivity and glare. We implanted a new zonal-progressive MIOL (AMO Array) in 31 eyes of 25 patien...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(13)80217-9
更新日期：1995-09-01 00:00:00
abstract：PURPOSE:To analyze risk factors and management of pupillary intraocular lens (IOL) capture after IOL transscleral fixation. SETTING:Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea. DESIGN:Retrospective case series. METHODS:A chart review was performed of patients who had transscle...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2017.08.021
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:To evaluate noncorneal astigmatism after implantation of a one-piece, plate-haptic silicone or one-piece poly(methyl methacrylate) PMMA intraocular lens (IOL). SETTING:Klinik und Poliklinik für Augenheilkunde der Universität Regensburg, Germany. METHODS:After a follow-up of at least 3 months, the degree of po...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(97)80117-4
更新日期：1997-11-01 00:00:00
abstract：PURPOSE:To assess the accuracy of the scanning electron microscopy (SEM) and present alternative approaches to quantify surface roughness based on numerical analysis. SETTING:Department of Ophthalmology, Maisonneuve-Rosemont Hospital, University of Montreal, Montreal, Quebec, Canada. DESIGN:Experimental study. METHO...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2012.08.050
更新日期：2013-01-01 00:00:00
abstract：:We report 2 cases of implantation with the Kamra corneal inlay to describe central and peripheral retinal visibility and the quality of optical coherence tomography (OCT) scans. Under pharmacological mydriasis, the central and peripheral retina was explored without disturbance by an experienced retinal ophthalmologist...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.07.002
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:To evaluate the results of photorefractive keratectomy (PRK) to treat undercorrected radial keratotomy (RK). SETTING:Instituto de Oftalmologia Tadeu Cvintal, São Paulo, Brazil. METHODS:A consecutive series of 28 eyes that had PRK to treat residual myopia after RK were studied. Refractive visual and safety dat...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80189-1
更新日期：1996-09-01 00:00:00
abstract：:The current trend toward implantation of posterior chamber lenses within the capsular bag rather than the ciliary sulcus seems logical in light of the increasing evidence of uveal damage from sulcus fixated posterior chamber lenses. However, long-term, successful capsular bag fixation has not been demonstrated with cu...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(87)80040-8
更新日期：1987-07-01 00:00:00
abstract：:Descemet-stripping automated endothelial keratoplasty (DSAEK) is an alternative to penetrating keratoplasty for the treatment of corneal endothelial disease that involves stripping diseased Descemet membrane (DM) from the recipient. Descemet membrane stripping is currently performed with a generic balanced salt soluti...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.01.037
更新日期：2008-06-01 00:00:00
abstract：UNLABELLED:We describe a case of unilateral corneal ectasia in a 26-year-old man following small-incision lenticule extraction. The preoperative corneal topography was normal, with a minimum corneal thickness of 511 μm and 513 μm in the right eye and left eye, respectively. Lenticules of 85 μm and 82 μm were fashioned ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2015.08.006
更新日期：2015-09-01 00:00:00
