Comparative study of PrPc expression in rat, monkey, and cow gastrointestinal tract.

abstract：:When cells are deprived of iron, their growth is invariably inhibited. However, the mechanism involved remains largely unclear. Recently, we have reported that subcytotoxic concentration of deferoxamine mesylate (DFO), an iron chelator, specifically inhibited transition of Chang cell, a normal hepatocyte cell line, fr...

journal_title：Annals of the New York Academy of Sciences

authors： Yoon YS,Cho H,Lee JH,Yoon G

更新日期：2004-04-01 00:00:00

abstract：:This article reviews research on the Finnish model of peer-group mentoring (PGM). The theoretical foundation of the model is based on the constructivist theory of learning, the concept of autonomy in teaching profession, peer learning, and narrative identity work. The model has been disseminated nationwide in the educ...

journal_title：Annals of the New York Academy of Sciences

authors： Tynjälä P,Pennanen M,Markkanen I,Heikkinen HLT

更新日期：2021-01-01 00:00:00

abstract：:The role of dopaminergic activity in susceptibility of methamphetamine (MAP) psychosis (flashbacks) to subsequent spontaneous recurrences was studied. Plasma monoamine metabolite levels were assayed in 23 flashbackers, of whom 10 experienced a single flashback, 8 exhibited subsequent flashbacks and 5 with the last epi...

journal_title：Annals of the New York Academy of Sciences

authors： Yui K,Goto K,Ikemoto S

更新日期：2004-10-01 00:00:00

abstract：:We have presented a perspective of progress in three areas of simulations of complex molecules: the development of force fields for molecular simulation; the application of computer graphics, molecular mechanics and molecular dynamics in simulations of DNA and DNA-drug complexes and the application of computer graphic...

journal_title：Annals of the New York Academy of Sciences

authors： Kollman PA,Weiner S,Seibel G,Lybrand T,Singh UC,Caldwell J,Rao SN

更新日期：1986-01-01 00:00:00

abstract：:Despite new technological advances in the rehabilitation of audition in profoundly deaf children, auditory training remains a fundamental part of their education. Consequently, it is necessary to learn what kind of stimuli, what kind of auditory tasks, and what kind of learning procedures generate faster and more long...

journal_title：Annals of the New York Academy of Sciences

authors： Rochette F,Bigand E

更新日期：2009-07-01 00:00:00

abstract：:The role of inflammation in atherosclerosis is well recognized. We have evaluated the allele frequencies of the +869T/C and +915G/C polymorphisms (SNPs) at the TGF-beta1 gene and -1082G/A SNP at IL-10 promoter sequence, two well-known immunosuppressive and anti-inflammatory cytokines, in patients with carotid stenosis...

journal_title：Annals of the New York Academy of Sciences

authors： Crivello A,Giacalone A,Scola L,Forte GI,Nuzzo D,Giacconi R,Cipriano C,Candore G,Mocchegiani E,Colonna-Romano G,Lio D,Caruso C

更新日期：2006-05-01 00:00:00

abstract：:Peripheral administration of lipopolysaccharide (LPS) in an amount that produces acute stress has been found to affect the catecholamine systems in the brain. Acute peripheral LPS administration activated norepinephrine (NE) metabolism in the locus ceruleus (LC). Approximately 40% of murine LC neurons project to the o...

journal_title：Annals of the New York Academy of Sciences

authors： Ota A,Mori K,Kaneko YS,Nakashima A,Nagatsu I,Nagatsu T

更新日期：2008-12-01 00:00:00

abstract：:Esophageal symptoms are common, and can arise from mucosal, motor, functional, and neoplastic processes, among others. Judicious use of diagnostic testing can help define the etiology of symptoms and can direct management. Endoscopy, esophageal high-resolution manometry (HRM), ambulatory pH or pH-impedance manometry, ...

journal_title：Annals of the New York Academy of Sciences

authors： Gyawali CP,de Bortoli N,Clarke J,Marinelli C,Tolone S,Roman S,Savarino E

更新日期：2018-12-01 00:00:00

abstract：:Previous studies have suggested that metabolic inhibition is neuroprotective, but little evidence has been provided to support this proposal. Using the in vitro rabbit retina preparation as an established model of the central nervous system (CNS), we measured the rate of glucose utilization and lactate production, and...

journal_title：Annals of the New York Academy of Sciences

authors： Maynard KI,Quiñones-Hinojosa A,Malek JY

更新日期：1999-01-01 00:00:00

abstract：:This communication summaries a series of observations of the transport function of the crypt of the rat distal colon. Development of methods to study both 22Na uptake by apical membrane vesicles prepared from crypt cells and intracellular pHi (pHi), fluid movement (Jv), and bicarbonate secretion during microperfusion ...

journal_title：Annals of the New York Academy of Sciences

authors： Binder HJ,Rajendran VM,Geibel JP

更新日期：2000-01-01 00:00:00

abstract：:In the basal state, patients with sarcoidosis have reduced numbers of circulating T lymphocytes and a normal number of circulating B lymphocytes. The lymphocytes show impaired DNA synthesis in response to several mitogens and antigens and impaired K-cell cytotoxicity. Circulating atypical cells of lymphocytic origin a...

journal_title：Annals of the New York Academy of Sciences

authors： Hedfors E

更新日期：1976-01-01 00:00:00

abstract：:Early dissemination, blood circulation, or homing of single tumor cells in bone marrow and other organs is usually undetectable at primary diagnosis, even by high resolution imaging technologies. However, ultrasensitive approaches now enable the detection of "occult" tumor cells. Many researchers are currently focusin...

journal_title：Annals of the New York Academy of Sciences

authors： Riethdorf S,Pantel K

更新日期：2010-10-01 00:00:00

abstract：:Western lifestyle, characterized by reduced physical activity and a diet rich in fat, refined carbohydrates, and animal protein is associated with high prevalence of overweight, metabolic syndrome, insulin resistance, and high plasma levels of several growth factors and sex hormones. Most of these factors are associat...

journal_title：Annals of the New York Academy of Sciences

authors： Berrino F,Villarini A,De Petris M,Raimondi M,Pasanisi P

更新日期：2006-11-01 00:00:00

abstract：:Nicotinamide can protect the NOD mouse from diabetes if given early enough and in sufficient dose. The effect partly wanes with time. There is reduced islet inflammation. Similar protective effects can be demonstrated in quasi-experimental interventions in humans--both diabetes related and unrelated deemed at risk of ...

journal_title：Annals of the New York Academy of Sciences

authors： Elliott RB,Pilcher CC,Stewart A,Fergusson D,McGregor MA

更新日期：1993-11-30 00:00:00

abstract：:Three distinct pathological conditions, related to different means by which dense intralabyrinthine particles interfere with the function of a semicircular canal and cause nystagmus and vertigo, are amenable to treatment with repositioning maneuvers. Known as benign paroxysmal positional vertigo and variants, these co...

journal_title：Annals of the New York Academy of Sciences

authors： Epley JM

更新日期：2001-10-01 00:00:00

abstract：:New approaches to the treatment of pulmonary arterial hypertension (PH) have increased symptomatic relief and prolonged survival. PH is a common sequela of the hemoglobinopathies, but the use of standard oral treatment options is limited because of toxicity and poor effectiveness. Sildenafil citrate is a selective and...

journal_title：Annals of the New York Academy of Sciences

authors： Derchi G,Forni GL

更新日期：2005-01-01 00:00:00

abstract：:A permanent decrease was seen in the prevalence of lice infestation among population of the Ukraine from 1990-2004. The prevalence of lice infestation among children under 14 years of age was 6-27 times more than that in adults. The highest figures were among children 7-14 years old. During all of the observation peri...

journal_title：Annals of the New York Academy of Sciences

authors： Kurhanova I

更新日期：2006-10-01 00:00:00

abstract：:A brief overview is presented of recently developed and currently emerging statistical and computational techniques that have been proved to be highly helpful in handling the avalanche of the new type of data generated by modern high-throughput technologies in experimental biology. The review, in no way comprehensive,...

journal_title：Annals of the New York Academy of Sciences

authors： Rosenfeld S

更新日期：2004-05-01 00:00:00

abstract：:Whole and nonadherent Peyer's patch cells were shown to present antigen to cloned antigen specific T-cells, albeit less efficiently than spleen cells. Unlike spleen cells, adherent PP cells did not present antigen, and PP lacked cells with classical dendritic morphology. The antigen presenting and MLR-stimulating cell...

journal_title：Annals of the New York Academy of Sciences

authors： Tomasi TB,Barr WG,Challacombe SJ,Curran G

更新日期：1983-06-30 00:00:00

abstract：:Many risk factors have been identified as having either a protective or a negative effect on the development of fibroids, but due to methodological issues and a lack of long-term studies, the exact effect of these factors is ambiguous. In similar dispute is the proper treatment of fibroids. Recent technological advanc...

journal_title：Annals of the New York Academy of Sciences

authors： Moorehead ME,Conard CJ

更新日期：2001-12-01 00:00:00

abstract：:Young songbirds memorize a tutor song and use the memory trace as a template to shape their own song by auditory feedback. Major issues in birdsong research include the neural sites and mechanisms for song memory and auditory feedback. The brain song control system contains neurons with both premotor and auditory func...

journal_title：Annals of the New York Academy of Sciences

authors： Konishi M

更新日期：2004-06-01 00:00:00

abstract：:Gene expression regulation, in particular at the level of transcription, has been demonstrated to play a key role in the development of human diseases, including cancer, and in bacteria it is crucial for proliferation as well as for pathogenicity. Transcriptional regulation is based on complex networks of interactions...

journal_title：Annals of the New York Academy of Sciences

authors： Zorrilla S,Lillo MP,Chaix D,Margeat E,Royer CA,Declerck N

更新日期：2008-01-01 00:00:00

abstract：:We are performing genomic searches in randomly ascertained families to identify new quantitative trait loci (QTLs) that influence atherosclerosis and its risk factors. The genetic markers used for genomic searches are random microsatellite markers distributed throughout the human chromosomes. These markers are used fo...

journal_title：Annals of the New York Academy of Sciences

authors： Hixson JE,Blangero J

更新日期：2000-05-01 00:00:00

abstract：:Immunoglobulin 4 (IgG4) is one of four human IgG subclasses and has several unique functional characteristics. It exhibits low affinity for complement and for most Fc receptors. It furthermore has generally high affinity for its antigen, with binding occurring in a monovalent fashion, as IgG4 can exchange Fab-arms wit...

journal_title：Annals of the New York Academy of Sciences

authors： Huijbers MG,Plomp JJ,van der Maarel SM,Verschuuren JJ

更新日期：2018-02-01 00:00:00

abstract：:The anatomy of the brain is extremely complex, and certain, even large structures, such as the corticospinal tract (CST), remain poorly understood. Diffusion tractography provides an opportunity to explore the white matter tracts in a fundamentally new way. In the current paper, we show how this technique has already ...

journal_title：Annals of the New York Academy of Sciences

authors： Holodny AI,Watts R,Korneinko VN,Pronin IN,Zhukovskiy ME,Gor DM,Ulug A

更新日期：2005-12-01 00:00:00

abstract：:Image processing in fluid mechanics has become an important quantitative tool for flow analysis. The feasibility of simultaneous measurements of instantaneous velocity and temperature fields, as well as for tracking interfaces, creates a functional tool to describe thermally driven flows accompanied by phase change. T...

journal_title：Annals of the New York Academy of Sciences

authors： Kowalewski TA

更新日期：2002-10-01 00:00:00

abstract：:The data presented above suggest that one possible clinical use of TGF-beta would be to protect the bone marrow from the effects of myelosuppressive chemotherapeutic drugs by preventing entry or removing primitive stem cells from the cell cycle. It may also have the additional benefit of reducing the drug-induced neut...

journal_title：Annals of the New York Academy of Sciences

authors： Ruscetti FW,Jacobsen SE,Birchenall-Roberts M,Broxmeyer HE,Engelmann GL,Dubois C,Keller JR

更新日期：1991-01-01 00:00:00

abstract：:Our paper reviews recent progress in the study and understanding of observed trends in extreme rainfall events in the Metropolitan Area of São Paulo (MASP). These are discussed in relation to hydrometeorological hazards that trigger natural disasters, such as flash floods, landslides, and droughts, that affect the pop...

journal_title：Annals of the New York Academy of Sciences

authors： Marengo JA,Alves LM,Ambrizzi T,Young A,Barreto NJC,Ramos AM

更新日期：2020-07-01 00:00:00

abstract：:Rapid cooling of small samples is necessary both to cryofixation for electron microscopy and to vitrification for cryopreservation. Several effects on the cooling rates of small samples quenched into liquid nitrogen were studied, including the diameter of samples, the subcooling of liquid nitrogen, the quenching speed...

journal_title：Annals of the New York Academy of Sciences

authors： Cao Q,Hua TC

更新日期：1998-09-11 00:00:00

abstract：:This preliminary study describes effects of two pharmacologic agents on erythrocyte behavior. Increased erythrocyte aggregation has been proposed as important in the pathogenesis of a number of disorders, but the exact mechanism by which it plays a role in disease production remains unclear. Several anionic amphophile...

journal_title：Annals of the New York Academy of Sciences

authors： McMillan DE,Utterback NG,Wujek JJ

更新日期：1983-01-01 00:00:00