A correlative study of in vivo and in vitro labeling index using bromodeoxyuridine in human brain tumors.

abstract：:Neurological complications may occur in the course of Waldenström's macroglobulinemia (Wm). These complications affect both the central and peripheral nervous system. Pathogenesis is debated and several mechanisms have been suggested. Direct malignant lymphoid infiltration (MLI) is very rare and has only been reported...

journal_title：Journal of neuro-oncology

authors： Massengo S,Riffaud L,Morandi X,Bernard M,Verin M

更新日期：2003-05-01 00:00:00

abstract：:Stereotactic radiosurgery is a frequently performed procedure for patients with benign intracranial tumors. Benign tumors are good candidates for radiosurgery because they are generally non-invasive, are well visualized by magnetic resonance imaging, and their slow rate of proliferation makes conventional radiation do...

journal_title：Journal of neuro-oncology

authors： Pollock BE

更新日期：2009-05-01 00:00:00

abstract：INTRODUCTION:This study evaluated an association between whole brain volume loss and neurocognitive decline following prophylactic cranial irradiation (PCI) for limited-stage small-cell lung cancer (SCLC). METHODS:This was a secondary analysis of a prospective clinical trial that accrued patients at a single instituti...

journal_title：Journal of neuro-oncology

authors： Gui C,Chintalapati N,Hales RK,Voong KR,Sair HI,Grimm J,Duhon M,Kleinberg LR,Vannorsdall TD,Redmond KJ

更新日期：2019-09-01 00:00:00

abstract：:Supratentorial primitive neuroectodermal tumors (sPNET) occurring in adults are rare. Only 56 such cases have been previously reported. This report documents a 56-year-old male who presented with the chief complaint of right facial palsy. Magnetic resonance imaging (MRI) revealed left frontal and bilateral periventric...

journal_title：Journal of neuro-oncology

authors： Ohba S,Yoshida K,Hirose Y,Ikeda E,Kawase T

更新日期：2008-01-01 00:00:00

abstract：:Children with high-grade glioma (HGG) have a poor prognosis compared to those with low-grade glioma (LGG). Adjuvant chemotherapy may be beneficial, but its optimal use remains undetermined. Histology and extent of resection are important prognostic factors. We tested the hypothesis that patients with midline HGG treat...

journal_title：Journal of neuro-oncology

authors： Eisenstat DD,Pollack IF,Demers A,Sapp MV,Lambert P,Weisfeld-Adams JD,Burger PC,Gilles F,Davis RL,Packer R,Boyett JM,Finlay JL

更新日期：2015-02-01 00:00:00

abstract：:To assess the clinical outcome and late side effect profile of pencil beam scanning proton therapy (PT) delivered to children with intracranial ependymoma. Between July-2004 and March-2013, 50 patients with intracranial ependymoma (n = 46, grade 3) received involved-field PT at Paul Scherrer Institute (PSI). Median ag...

journal_title：Journal of neuro-oncology

authors： Ares C,Albertini F,Frei-Welte M,Bolsi A,Grotzer MA,Goitein G,Weber DC

更新日期：2016-05-01 00:00:00

abstract：AIM:To assess whether extent of surrounding edema correlates with acute adverse clinical outcomes within 3 months after stereotactic radiosurgery (SRS) for melanoma brain metastases (BM). METHODS:Patients with melanoma BM treated with SRS were included in a single center retrospective analysis. A contrast-enhanced mag...

journal_title：Journal of neuro-oncology

authors： Jardim A,Scott J,Drew Z,Foote MC,Sadasivan AP,Hall B,Olson SL,Shanker M,Pinkham MB

更新日期：2019-12-01 00:00:00

abstract：:The name of author Do Hoon Lim was incorrect in the initial online publication. The original article has been corrected. ...

journal_title：Journal of neuro-oncology

authors： Wee CW,Kim IH,Park CK,Kim N,Suh CO,Chang JH,Lim DH,Nam DH,Kim IA,Kim CY,Oh YT,Chung WK,Kim SH

更新日期：2020-05-01 00:00:00

abstract：:Optimal treatment of recurrent glioblastoma multiforme (rGBM) in elderly and/or frail patients remains virtually unexplored, the best supportive care (BSC) only is routinely administered due to the fatal prognosis. We evaluated the impact of different treatment methods on post-progression survival (PPS) and overall su...

journal_title：Journal of neuro-oncology

authors： Socha J,Kepka L,Ghosh S,Roa W,Kumar N,Sinaika V,Matiello J,Lomidze D,de Castro DG,Hentati D,Fidarova E

更新日期：2016-02-01 00:00:00

abstract：INTRODUCTION:Low-grade glioma (LGG) represent the most common pediatric central nervous system tumor. When total surgical resection is not feasible, chemotherapy is first-line therapy in children. Multiple pediatric LGG chemotherapy regimens have been investigated with variable 2-year event free survival (EFS) rates of...

journal_title：Journal of neuro-oncology

authors： Nellan A,Wright E,Campbell K,Davies KD,Donson AM,Amani V,Judd A,Hemenway MS,Raybin J,Foreman NK,Rush S,Dorris K

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Intracranial meningiomas rarely present with multiple lesions. To the best of our knowledge, current literature regarding meningiomatosis (MM) is mostly comprised of small case series and individual reports. Hence, survival outcome data are limited. The Objective of this study is to explore the influence o...

journal_title：Journal of neuro-oncology

authors： Ramos-Fresnedo A,Domingo RA,Vivas-Buitrago T,Lundy L,Trifiletti DM,Jentoft ME,Desai AB,Quiñones-Hinojosa A

更新日期：2020-09-01 00:00:00

abstract：:A positron emission tomography study using [18F]-fluorodeoxyglucose was undertaken to identify and quantitate whether diaschisis occurred in cerebral cortex, basal ganglia, or thalamus, as well as in cerebellar cortex and dentate nuclei in patients with malignant glioma. The relationship between diaschisis in these ce...

journal_title：Journal of neuro-oncology

authors： Rozental JM,Levine RL,Nickles RJ,Dobkin JA,Hanson JM

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor that presents histological features and biological behavior of low-grade malignancy. The authors report a case of malignant intracranial EHE, in which surgical excisions and additional immuno-chemotherapy were ineffective. Emphasis...

journal_title：Journal of neuro-oncology

authors： Endo T,Su CC,Numagami Y,Shirane R

更新日期：2004-05-01 00:00:00

abstract：:Hypoxia-inducible factor (HIF)-1α and HIF-2α expression were investigated immunohistochemically as determinants of prognosis in 42 cases of astrocytic tumors associated with necrosis grade on magnetic resonance (MR) imaging. Expression of HIF-1α was determined immunohistologically. The degree of necrosis on MR images ...

journal_title：Journal of neuro-oncology

authors： Mashiko R,Takano S,Ishikawa E,Yamamoto T,Nakai K,Matsumura A

更新日期：2011-03-01 00:00:00

abstract：:Primary intramedullary spinal cord tumors are a rare entity, comprising 4–10 %of all spinal cord tumors. The current report presents data on intramedullary spinal cord anaplastic astrocytomas and glioblastomas in adults using the national surveillance, epidemiology, and end results database (1973–2008), and evaluates ...

journal_title：Journal of neuro-oncology

authors： Wong AP,Dahdaleh NS,Fessler RG,Melkonian SC,Lin Y,Smith ZA,Lam SK

更新日期：2013-12-01 00:00:00

abstract：:To date, no histopathological vascular investigation focusing on peritumoral brain zone (PBZ) has been reported for glioblastoma. We analyzed 10 newly diagnosed cases of glioblastomas. For these PBZs, histopathological investigation was performed by hematoxylin-eosin (H&E) staining and immunohistochemistry was analyze...

journal_title：Journal of neuro-oncology

authors： Tamura R,Ohara K,Sasaki H,Morimoto Y,Yoshida K,Toda M

更新日期：2018-01-01 00:00:00

abstract：:Communication support tools (CST) improve patient outcomes in oncology including: knowledge, satisfaction, self-management, and adherence to planned treatment. Little is known about communication support tools use in patients with primary or secondary brain tumours. We aimed to explore cognitive function and communica...

journal_title：Journal of neuro-oncology

authors： Naehrig DN,Koh ES,Vogiatzis M,Yanagisawa W,Kwong C,Shepherd HL,Milross C,Dhillon HM

更新日期：2016-01-01 00:00:00

abstract：:Primary malignant brain and other central nervous system tumors (BT) are a rare cancer that causes morbidity and mortality disproportionate to their incidence. This study presents the most up-to-date mortality data for malignant BT in the United States (US) by histology groupings, age, race, and sex. Mortality rates f...

journal_title：Journal of neuro-oncology

authors： Gittleman H,Kromer C,Ostrom QT,Blanda R,Russell J,Kruchko C,Barnholtz-Sloan JS

更新日期：2017-06-01 00:00:00

abstract：:Pediatric brain gliomas are not always amenable for complete surgical excision, therefore adjuvant treatment for a large tumor mass is often required. As tumor volume shrinkage may not be a reliable method for assessing response to treatment, information about the tumor growth potential is desirable for an adequate fo...

journal_title：Journal of neuro-oncology

authors： Lazareff JA,Gupta RK,Alger J

更新日期：1999-02-01 00:00:00

abstract：:The aim of this work was to determine the accuracy and precision of stereotactic localization and treatment delivery using a helical tomotherapy based stereotactic radiosurgery (SRS) system. A tomotherapy specific radiosurgery workflow was designed that exploits the system's on board megavotage CT (MVCT) imaging syste...

journal_title：Journal of neuro-oncology

authors： Soisson ET,Hardcastle N,Tomé WA

更新日期：2010-06-01 00:00:00

abstract：:Papillary meningioma is a rare subtype of meningioma that often behaves aggressively. In order to characterize factors that may influence this behavior, we chose to compare MIB-1 labeling index (LI) and telomerase RNA localization (hTR) in papillary meningiomas, meningiomas, and atypical meningiomas. LI is now often u...

journal_title：Journal of neuro-oncology

authors： Rushing EJ,Colvin SM,Gazdar A,Miura N,White CL 3rd,Coimbra C,Burns DK

更新日期：1999-01-01 00:00:00

abstract：:5-aminolevulinic acid (5-ALA) introduction in the surgical management of Glioblastoma (GBM) enables the intra-operatively identification of cancer cells in the mass by means of fluorescence. Here, we analyzed the phenotype of GBM cells isolated from distinct tumour areas determined by 5-ALA (tumour core, 5-ALA intense...

journal_title：Journal of neuro-oncology

authors： Rampazzo E,Della Puppa A,Frasson C,Battilana G,Bianco S,Scienza R,Basso G,Persano L

更新日期：2014-02-01 00:00:00

abstract：:This study concerns the use of the MTT [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H tetrazolium bromide] colorimetric assay to evaluate the chemosensitivity of the C6 rat glioma cell line to a panel of twelve chemotherapeutic agents. In a previous study of in vitro chemosensitivity of human glioma cell lines, the pre...

journal_title：Journal of neuro-oncology

authors： Hand CM,Vender JR,Black P

更新日期：1998-01-01 00:00:00

abstract：:Intracranial Hodgkin's lymphoma (ICHL) in the HIV positive population is a rarely reported event with only three prior cases reported in the literature. In these prior reports, the outcome of the patients was uncertain or very poor. We report here the case of an HIV seropositive patient with an isolated intracranial r...

journal_title：Journal of neuro-oncology

authors： Ramchandar K,Verhey LH,Jha NK,Murty NK,McMillan W

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:There is an increasing interest in local tumor ablative treatment modalities that induce immunogenic cell death and the generation of antitumor immune responses. METHODS:We report six recurrent glioblastoma patients who were treated with intracavitary thermotherapy after coating the resection cavity wall wi...

journal_title：Journal of neuro-oncology

authors： Grauer O,Jaber M,Hess K,Weckesser M,Schwindt W,Maring S,Wölfer J,Stummer W

更新日期：2019-01-01 00:00:00

abstract：:Twenty patients suspected of meningeal carcinomatosis (MC) secondary to small cell carcinoma of the lung were evaluated by myelography and by cytologic examination of cerebrospinal fluid (CSF). In 4 patients both investigations demonstrated MC. Four had positive cytology but a negative myelogram. Five patients had a p...

journal_title：Journal of neuro-oncology

authors： Pedersen AG,Paulson OB,Gyldensted C

更新日期：1985-01-01 00:00:00

abstract：:Thermal stability signatures of complex molecule interaction in biological fluids can be measured using a new approach called differential scanning calorimetry (DSC). The thermal stability of plasma proteome has been described previously as a method of producing a disease-specific "signature," termed thermogram, in se...

journal_title：Journal of neuro-oncology

authors： Chagovetz AA,Jensen RL,Recht L,Glantz M,Chagovetz AM

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Malignant peripheral nerve sheath tumors (MPNSTs) are rare tumors, generally high-grade, and comprise ~ 5-10% of soft tissue sarcomas. Over two-thirds of MPNSTs metastasize, and upwards of 40% clinically recur. Etiologic risk factors for MPNSTs are historically understudied. There is evidence to suggest MPNS...

journal_title：Journal of neuro-oncology

authors： Peckham-Gregory EC,Montenegro RE,Stevenson DA,Viskochil DH,Scheurer ME,Lupo PJ,Schiffman JD

更新日期：2018-08-01 00:00:00

abstract：:Type 2 diabetes mellitus (DM) and obesity are known risk factors for poor outcomes in patients with systemic malignancies but are not well-studied in the brain tumor population. In this study we asked if type 2 DM and elevated body mass index (BMI) are independent risk factors for poor prognosis in patients with high-...

journal_title：Journal of neuro-oncology

authors： Chambless LB,Parker SL,Hassam-Malani L,McGirt MJ,Thompson RC

更新日期：2012-01-01 00:00:00

abstract：:Membrane-type MMPs (MT-MMPs) constitute a growing subclass of recently identified matrix metalloproteinases (MMPs). In addition to the highly conserved MMP functional domains, the MT-MMPs have additional insertion sequences (IS) that confer unique functional roles. While most of the MMPs are secreted, the MT-MMPs are ...

journal_title：Journal of neuro-oncology

authors： Fillmore HL,VanMeter TE,Broaddus WC

更新日期：2001-06-01 00:00:00