A supratentorial primitive neuroectodermal tumor in an adult: a case report and review of the literature.

abstract：:Gamma Knife surgery (GKS) has emerged as a valuable adjuvant treatment modality for recurrent or residual craniopharyngioma. However, prognostic factors pertaining to progression-free survival (PFS) remain poorly understood. A study was conducted to address this issue. A total of 37 consecutive patients undergoing 39 ...

journal_title：Journal of neuro-oncology

authors： Xu Z,Yen CP,Schlesinger D,Sheehan J

更新日期：2011-08-01 00:00:00

abstract：:We report a case of a 2 year-old boy who initially presented with macrocephaly and severe global developmental delay. Imaging revealed a large left temporo-parietal mass that was lobulated, calcified, focally enhancing and partially cystic. A second surgery was required for tumor recurrence approximately one year late...

journal_title：Journal of neuro-oncology

authors： Dunham C,Sugo E,Tobias V,Wills E,Perry A

更新日期：2007-08-01 00:00:00

abstract：:Compared to classical oncological outcome measures such as time to progression and survival, the importance of cognitive functioning in patients with diffuse infiltrative brain tumors has only recently been recognized. Apart from the relatively low incidence and the invariably fatal outcome of gliomas, the general ass...

journal_title：Journal of neuro-oncology

authors： Klein M,Duffau H,De Witt Hamer PC

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Lymphomatoid granulomatosis (LYG) is an angiocentric and angiodestructive lymphoreticular proliferation, which usually involves the lungs, but may also involve the central nervous system (CNS). Unique involvement of the CNS has been reported rarely. We report our experience with LYG confined to the brain and...

journal_title：Journal of neuro-oncology

authors： Lucantoni C,De Bonis P,Doglietto F,Esposito G,Larocca LM,Mangiola A,Martini M,Papacci F,Teofili L,Pompucci A

更新日期：2009-09-01 00:00:00

abstract：:Two distinct mechanisms, vasculogenesis and angiogenesis implement the formation of the vascular network in the embryo. Vasculogenesis gives rise to the heart and the first primitive vascular plexus inside the embryo and in its surrounding membranes, as the yolk sac circulation. Angiogenesis is responsible for the rem...

journal_title：Journal of neuro-oncology

authors： Patan S

更新日期：2000-10-01 00:00:00

abstract：:Neural stem cells (NSC) have unique differentiation-, proliferation-, and motility properties. To investigate whether they secrete factors that interfere with the proliferation of glioma cells, we grew glioma cells in conditioned medium (CM) obtained from cultures of neurospheres including neural stem / progenitor cel...

journal_title：Journal of neuro-oncology

authors： Suzuki T,Izumoto S,Wada K,Fujimoto Y,Maruno M,Yamasaki M,Kanemura Y,Shimazaki T,Okano H,Yoshimine T

更新日期：2005-09-01 00:00:00

abstract：:We present a case of de novo fibrosarcoma in a 43-year-old male, with MRI documented evolution from a 5 mm hyperintense area to 5 cm tumor mass in a 12-month period. The diagnosis of low-grade fibrosarcoma was established by three experienced neuropathologists. The patient underwent gross total resection with adjuvant...

journal_title：Journal of neuro-oncology

authors： Adeleye AO,Fellig Y,Umansky F,Shoshan Y

更新日期：2009-04-01 00:00:00

abstract：:The diagnosis of a high-grade glioma usual is followed by functional impairment(s), cognitive decline and an impaired psycho-social well-being. This might well have a significant and negative impact on the health related quality of life. The purpose of this study was to explore physical activity levels, prevalence and...

journal_title：Journal of neuro-oncology

authors： Piil K,Jakobsen J,Christensen KB,Juhler M,Jarden M

更新日期：2015-09-01 00:00:00

abstract：:The aim of this study was to test by means of a voxel-based approach the hypothesis that there is a different spatial distribution of brain metastases (BM) and white matter hyperintensities (WMH) and that the presence of WMH affects the location of BM in lung and non-lung cancer patients. Two-hundred consecutive cance...

journal_title：Journal of neuro-oncology

authors： Quattrocchi CC,Errante Y,Mallio CA,Carideo L,Scarciolla L,Santini D,Tonini G,Zobel BB

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:A major challenge to developing new therapies for patients with malignant brain tumors is that relatively few small molecule anticancer drugs penetrate the blood-brain barrier (BBB) well enough to provide therapeutically effective concentrations in brain tissue before drug exposure in non-CNS tissues results in...

journal_title：Journal of neuro-oncology

authors： Ciesielski MJ,Bu Y,Munich SA,Teegarden P,Smolinski MP,Clements JL,Lau JYN,Hangauer DG,Fenstermaker RA

更新日期：2018-12-01 00:00:00

abstract：:Both cell proliferation and cell death occur simultaneously in tumor tissue, and extent of tumor growth reflects the net balance of these events. We correlated cell proliferation, spontaneous cell death, and alterations in tumor suppressor proteins with one another and with survival of patients with primary astrocytic...

journal_title：Journal of neuro-oncology

authors： Nakamizo A,Inamura T,Ikezaki K,Yoshimoto K,Inoha S,Mizoguchi M,Amano T,Fukui M

更新日期：2002-04-01 00:00:00

abstract：:Differentiating neoplastic from non-neoplastic intracranial lesions is of paramount importance for patient management. Benign lesions can have many of the features of malignant brain tumors on both computed tomography (CT) and conventional magnetic resonance imaging (MRI). Herewith, we set out to investigate the role ...

journal_title：Journal of neuro-oncology

authors： Fotopoulos AD,Kyritsis AP,Tsiouris S,Al-Boucharali J,Papadopoulos A,Voulgaris S,Alexiou GA

更新日期：2011-01-01 00:00:00

abstract：:We report a case of association of a brain tumor with multiple colorectal polyposis and offer an analysis of the relevant literature with a view to revising the classification of the syndrome in relation to familial multiple polyposis and Gardner's syndrome. Differences emerged, depending on the brain tumor type, whic...

journal_title：Journal of neuro-oncology

authors： Cervoni L,Celli P,Tarantino R,Fortuna A

更新日期：1995-01-01 00:00:00

abstract：:The aim of this study is to evaluate prognostic factors of brain metastases from hepatocellular carcinoma. Medical records of 95 patients who have been diagnosed of brain metastases from hepatocellular carcinoma between January 2000 and December 2011 were retrospectively reviewed. The median age at diagnosis of brain ...

journal_title：Journal of neuro-oncology

authors： Kim KS,Kim K,Chie EK,Kim YJ,Yoon JH,Lee HS,Ha SW

更新日期：2014-10-01 00:00:00

abstract：:We have investigated the anti-tumor activity of ex vivo activated and expanded T cells which had been sensitized in vivo to one of two different syngeneic rat glioma cell lines; D74 or RT-2. Rats were sensitized by inoculation of irradiated tumor cells into each hind foot pad. After 10 days, the tumor-draining lymph n...

journal_title：Journal of neuro-oncology

authors： Rice CD,Baldwin NG,Biron RT,Bear HD,Merchant RE

更新日期：1997-03-01 00:00:00

abstract：:Craniopharyngiomas and pituitary adenomas are both tumors of the hypothalamic and pituitary region, respectively that are frequently associated with endocrine defects either because of direct involvement of hormone producing cells (most pituitary tumors) or because of secondary defects due to disturbance of hypothalam...

journal_title：Journal of neuro-oncology

authors： Oikonomou E,Barreto DC,Soares B,De Marco L,Buchfelder M,Adams EF

更新日期：2005-07-01 00:00:00

abstract：:The current study reports longitudinal coping responses among parents of children diagnosed with an embryonal brain tumor. Patients (n = 219) were enrolled on a treatment protocol for a pediatric embryonal brain tumor. Their parents (n = 251) completed the Coping Response Inventory at time of their child's diagnosis a...

journal_title：Journal of neuro-oncology

authors： Palmer SL,Lesh S,Wallace D,Bonner MJ,Swain M,Chapieski L,Janzen L,Mabbott D,Knight S,Boyle R,Armstrong CL,Gajjar A

更新日期：2011-11-01 00:00:00

abstract：:p53 mutations are the most frequently detected genetic alterations of gliomas, appearing in a similar proportion of low and high grade astrocytomas, while the amplification of epidermal growth factor receptor (EGFR) gene appears mainly in glioblastomas. Thus, these changes seem to delineate two subgroups of high grade...

journal_title：Journal of neuro-oncology

authors： Kordek R,Biernat W,Alwasiak J,Maculewicz R,Yanagihara R,Liberski PP

更新日期：1995-10-01 00:00:00

abstract：:The time to tumor progression (TTP), time to death (TTD) and complications were studied prospectively in a cohort of patients treated by surgery and adjuvant radio- and intensified PCV chemotherapy for astrocytomas (AIII), oligodendrogliomas (OIII) and oligoastrocytomas (OAIII) WHO grade III. The treatment was carried...

journal_title：Journal of neuro-oncology

authors： Kristof RA,Neuloh G,Hans V,Deckert M,Urbach H,Schlegel U,Simon M,Schramm J

更新日期：2002-09-01 00:00:00

abstract：:Extra-axial cerebellopontine angle (CPA) tumors account for approximately 10% of all brain neoplasms in adults. Vestibular schwannomas are the most common, followed by meningiomas. Gliomas in the CPA are rare and quite often are the exophytic extension of primary brain stem or cerebellar tumors. We describe a pilocyti...

journal_title：Journal of neuro-oncology

authors： Francesco F,Maurizio I,Stefano C,Marina S,Ugo S,Massimo S

更新日期：2010-04-01 00:00:00

abstract：:We conducted a phase II study to test methotrexate (5 g/m(2)), as a single agent prior to radiochemotherapy for pediatric high-grade glioma and diffuse intrinsic pontine glioma. Thirty patients (19 male, median age 10.8) were enrolled. Tumors were located as follows: cortex 10, pons 7, other 13. Tumor resection was cl...

journal_title：Journal of neuro-oncology

authors： Wolff JE,Kortmann RD,Wolff B,Pietsch T,Peters O,Schmid HJ,Rutkowski S,Warmuth-Metz M,Kramm C

更新日期：2011-05-01 00:00:00

abstract：:Identification of cytotoxic T lymphocyte (CTL) epitopes from additional tumor antigens is essential for the development of specific immunotherapy of malignant tumors. Neuritin, a recently discovered antigen overexpressed in astrocytoma, is considered to be a promising target for biological therapy. In the present stud...

journal_title：Journal of neuro-oncology

authors： Yang Z,Zhao T,Liu Y,Gong Z,Cheng S,Yang Q

更新日期：2013-08-01 00:00:00

abstract：:The Notch signal regulates both cell viability and apoptosis, and maintains stemness of various cancers including glioblastoma (GBM). Although Notch signal inhibition may be an effective strategy in treating GBM initiating cells (GICs), its applicability to the different subtypes of GBM remains unclear. Here, we analy...

journal_title：Journal of neuro-oncology

authors： Tanaka S,Nakada M,Yamada D,Nakano I,Todo T,Ino Y,Hoshii T,Tadokoro Y,Ohta K,Ali MA,Hayashi Y,Hamada J,Hirao A

更新日期：2015-01-01 00:00:00

abstract：:Central neurocytomas are uncommon intraventricular neoplasms whose optimal management remains controversial due to their rarity. We assessed outcomes for a historical cohort of neurocytoma patients and evaluated effects of tumor atypia, size, resection extent, and adjuvant radiotherapy. Progression-free survival (PFS)...

journal_title：Journal of neuro-oncology

authors： Imber BS,Braunstein SE,Wu FY,Nabavizadeh N,Boehling N,Weinberg VK,Tihan T,Barnes M,Mueller S,Butowski NA,Clarke JL,Chang SM,McDermott MM,Prados MD,Berger MS,Haas-Kogan DA

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Ferumoxtran-10 belongs to the Ultra Small Particles of Iron Oxide (USPIO) class of contrast agents and induces delayed tumor enhancement in brain tumors, reflecting the trapping of iron oxide particles by the macrophages and activated microglia. The aim of the study was to compare Ferumoxtran-10 contrast enhanc...

journal_title：Journal of neuro-oncology

authors： Kremer S,Pinel S,Védrine PO,Bressenot A,Robert P,Bracard S,Plénat F

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:To study the metabolic effects in vivo of L-2, 4 diaminobutyric acid (DAB) administered by retrograde microdialysis in glioblastoma and to evaluate the feasibility of the technique. METHODS:In 10 patients with glioblastoma, a stereotactic biopsy was performed followed by implantation of microdialysis cathet...

journal_title：Journal of neuro-oncology

authors： Bergenheim AT,Roslin M,Ungerstedt U,Waldenström A,Henriksson R,Ronquist G

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:Because raised matrix metalloprotease (MMP) levels are associated with glioma invasion and angiogenesis, we tested the efficacy of marimastat (MT) an orally active drug that can reduce MMP levels, in patients with gliomas. PATIENTS AND METHODS:A total of 162 patients with intracranial glioblastoma multiforme o...

journal_title：Journal of neuro-oncology

authors： Levin VA,Phuphanich S,Yung WK,Forsyth PA,Maestro RD,Perry JR,Fuller GN,Baillet M

更新日期：2006-07-01 00:00:00

abstract：:Aneurysmal bone cysts (ABCs) are benign bone lesions with annual incidences ranging from 1.4 to 3.2 cases per million people. Approximately, 10-30% of ABCs are found in the spine. Such lesions are traditionally treated with curettage or other intralesional techniques. Because ABCs can be locally aggressive, intralesio...

journal_title：Journal of neuro-oncology

authors： Boriani S,Lo SF,Puvanesarajah V,Fisher CG,Varga PP,Rhines LD,Germscheid NM,Luzzati A,Chou D,Reynolds JJ,Williams RP,Zadnik P,Groves M,Sciubba DM,Bettegowda C,Gokaslan ZL,AOSpine Knowledge Forum Tumor.

更新日期：2014-10-01 00:00:00

abstract：:Alkaline phosphatase (ALPase) and Mg2+-activated ATPase (Mg2+-ATPase) activities were demonstrated in human brain tumors by light and electron microscopy. Four cases of glioma, i.e., two cases of astrocytoma, grade II, and two cases of glioblastoma, were used as materials. At the light microscopic level, Mg2+-ATPase a...

journal_title：Journal of neuro-oncology

authors： Maeda T,Nishiyama F,Ogashiwa M,Takeuchi K,Hirano H

更新日期：1985-01-01 00:00:00

abstract：:Epigenetic silencing of the O(6)-methylguanine-DNA-methyltransferase (MGMT) gene by promoter methylation is correlated with improved progression-free survival (PFS) and overall survival (OS) in adult patients with newly diagnosed glioblastoma multiforme (GBM) who receive alkylating agents. The aim of this study is to ...

journal_title：Journal of neuro-oncology

authors： Minniti G,Salvati M,Arcella A,Buttarelli F,D'Elia A,Lanzetta G,Esposito V,Scarpino S,Maurizi Enrici R,Giangaspero F

更新日期：2011-04-01 00:00:00