Diarrhea in terminally ill patients: pathophysiology and treatment.

Abstract:

:Diarrhea is a distressing symptom that limits the quality of life in terminally ill patients. In these patients, many factors can affect intestinal secretion, absorption, and motility, including drugs, infective agents, antibiotics, chemotherapy, radiotherapy, surgery, malnutrition, neuroendocrine tumors, and mechanical bowel obstruction. Diarrhea can result in water and electrolyte losses. This review discusses the pathophysiology, assessment, and treatment of diarrhea in advanced cancer patients.

journal_name

J Pain Symptom Manage

authors

Mercadante S

doi

10.1016/0885-3924(95)00007-L

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

298-309

issue

4

eissn

0885-3924

issn

1873-6513

pii

0885-3924(95)00007-L

journal_volume

10

pub_type

杂志文章,评审
  • Trajectories of Symptom Occurrence and Severity From Before Through Five Months After Lung Cancer Surgery.

    abstract:CONTEXT:Limited information is available about lung cancer patients' symptoms in the pre- and postoperative periods. OBJECTIVES:Study purposes were to evaluate for changes in symptom occurrence and severity from the preoperative period to five months after surgery and to evaluate for predictors of the occurrence and t...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2014.11.297

    authors: Oksholm T,Rustoen T,Cooper B,Paul SM,Solberg S,Henriksen K,Kongerud JS,Miaskowski C

    更新日期:2015-06-01 00:00:00

  • Consensus Building on Health Indicators to Assess PC Global Development With an International Group of Experts.

    abstract:CONTEXT:International consensus on indicators is necessary to standardize the global assessment of palliative care (PC) development. OBJECTIVES:To identify the best indicators to assess current national-level PC development. METHODS:Experts in PC development were invited to rate 45 indicators organized by domains of ...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2019.04.024

    authors: Arias-Casais N,Garralda E,López-Fidalgo J,Rhee JY,Pons JJ,de Lima L,Centeno C

    更新日期:2019-09-01 00:00:00

  • Multidisciplinary management of cancer pain: a longitudinal retrospective study on a cohort of end-stage cancer patients.

    abstract::The epidemiology of cancer pain and the outcomes associated with pain treatments were investigated through a retrospective survey of 772 patients with advanced cancer. The cumulative prevalence of pain was 87%, including all types of cancer. Mean duration of pain was 6.9+/-8.1 months. The prevalence of pain was 28%, 4...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2006.05.017

    authors: Peng WL,Wu GJ,Sun WZ,Chen JC,Huang AT

    更新日期:2006-11-01 00:00:00

  • Obtaining informed consent for cancer pain research: do patients with advanced cancer and patients with chronic pain have different concerns?

    abstract::To explore the factors that patients with malignant and nonmalignant pain consider when deciding whether to enroll in pain research studies, determine whether their views are different, and determine whether willingness to enroll in research is associated with pain severity, semi-structured interviews were conducted w...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/s0885-3924(02)00527-4

    authors: Casarett D,Karlawish J,Sankar P,Hirschman KB,Asch DA

    更新日期:2002-11-01 00:00:00

  • The effect of a multimodal intervention on treatment-related symptoms in patients undergoing hematopoietic stem cell transplantation: a randomized controlled trial.

    abstract::Studies applying exercise, relaxation training, and psychoeducation have each indicated a positive impact on physical performance and/or psychological factors in patients diagnosed with cancer. We explored the longitudinal effect of a combination of these interventions on treatment-related symptoms in patients undergo...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jpainsymman.2008.09.005

    authors: Jarden M,Nelausen K,Hovgaard D,Boesen E,Adamsen L

    更新日期:2009-08-01 00:00:00

  • Independent validation of the modified prognosis palliative care study predictor models in three palliative care settings.

    abstract:CONTEXT:Accurate prognostic information in palliative care settings is needed for patients to make decisions and set goals and priorities. The Prognosis Palliative Care Study (PiPS) predictor models were presented in 2011, but have not yet been fully validated by other research teams. OBJECTIVES:The primary aim of thi...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jpainsymman.2014.10.010

    authors: Baba M,Maeda I,Morita T,Hisanaga T,Ishihara T,Iwashita T,Kaneishi K,Kawagoe S,Kuriyama T,Maeda T,Mori I,Nakajima N,Nishi T,Sakurai H,Shimoyama S,Shinjo T,Shirayama H,Yamada T,Ono S,Ozawa T,Yamamoto R,Tsuneto S

    更新日期:2015-05-01 00:00:00

  • Cardiac pacemakers and implantable defibrillators in terminal care.

    abstract::The use of cardiac pacemakers and arrhythmia control devices is increasingly common. The presence of a previously placed pacemaker or implantable cardioverter-defibrillator (ICD) in a terminally ill patient may result in medical and ethical issues for the patient, family, and healthcare provider. Two cases are present...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/s0885-3924(99)00038-x

    authors: Braun TC,Hagen NA,Hatfield RE,Wyse DG

    更新日期:1999-08-01 00:00:00

  • Differences in Symptom Burden Among Patients With Moderate, Severe, or Very Severe Chronic Obstructive Pulmonary Disease.

    abstract:CONTEXT:The symptom experience of patients with chronic obstructive pulmonary disease (COPD) is extremely complex. It is characterized by multiple co-occurring symptoms. However, very few studies have described this experience in COPD patients. OBJECTIVES:The aims of this study were to evaluate for differences in symp...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2015.12.324

    authors: Christensen VL,Holm AM,Cooper B,Paul SM,Miaskowski C,Rustøen T

    更新日期:2016-05-01 00:00:00

  • Day-to-day titration to initiate transdermal fentanyl in patients with cancer pain: short- and long-term experiences in a prospective study of 39 patients.

    abstract::Initial dose finding in patients with cancer pain who are started on TTS fentanyl (Duragesic, TTS-F) is often unsatisfactory with currently recommended doses and intervals. Acknowledging that studies reveal a "psuedo steady state" 15 to 20 hr after application of TTS-F, we prospectively investigated an increased initi...

    journal_title:Journal of pain and symptom management

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0885-3924(95)00162-x

    authors: Korte W,de Stoutz N,Morant R

    更新日期:1996-03-01 00:00:00

  • A double-blind, randomized, crossover comparison between single-dose and double-dose immediate-release oral morphine at bedtime in cancer patients.

    abstract::The European Association for Palliative Care guidelines for treatment of cancer pain recommend a double dose (DD) of immediate-release morphine at bedtime instead of single doses (SD) repeated every four hours throughout the night. A previous open controlled study reported more side effects after DD than after SD. The...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jpainsymman.2007.12.016

    authors: Dale O,Piribauer M,Kaasa S,Moksnes K,Knobel H,Klepstad P

    更新日期:2009-01-01 00:00:00

  • The complexity of nurses' attitudes and practice of sedation at the end of life: a systematic literature review.

    abstract:CONTEXT:Sedation is administered to some palliative care patients at the end of their life. Nurses play an important role in this practice. OBJECTIVES:To systematically review the evidence on nurses' attitudes and practice of end-of-life sedation. METHODS:We searched eight electronic databases, four key palliative ca...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章,评审

    doi:10.1016/j.jpainsymman.2013.06.011

    authors: Abarshi EA,Papavasiliou ES,Preston N,Brown J,Payne S,EURO IMPACT.

    更新日期:2014-05-01 00:00:00

  • A method for defining and estimating the palliative care population.

    abstract::Palliative care research is challenged by a disagreement as to what palliative care is, when it should be offered and what conditions warrant specialized palliative care services. These challenges became evident when we used a population-based data linkage to evaluate the delivery of palliative care services in Wester...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2005.12.018

    authors: McNamara B,Rosenwax LK,Holman CD

    更新日期:2006-07-01 00:00:00

  • Idiopathic Pulmonary Fibrosis: A Review of Disease, Pharmacological, and Nonpharmacological Strategies With a Focus on Symptoms, Function, and Health-Related Quality of Life.

    abstract::Despite several advances in treatment, idiopathic pulmonary fibrosis (IPF) remains a progressive, symptomatic, and terminal disease in patients not suitable for lung transplantation. With disease progression, IPF often leads to a constellation of symptoms, including dyspnea, cough, anxiety, and depression. Palliative ...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2019.12.364

    authors: Rozenberg D,Sitzer N,Porter S,Weiss A,Colman R,Reid WD,Shapera S,Fisher J,Wentlandt K

    更新日期:2020-06-01 00:00:00

  • Integrating palliative care into national policies.

    abstract::Good policies lay the groundwork for an effective health care system and society. They facilitate the implementation of palliative care programs aimed at providing care for all people in need of these services, and they ensure equitable access to affordable medications and therapies. The lack of good policies can lead...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章,评审

    doi:10.1016/j.jpainsymman.2007.02.031

    authors: Stjernswärd J,Foley KM,Ferris FD

    更新日期:2007-05-01 00:00:00

  • Identification of Symptom Clusters and Their Influencing Factors in Subgroups of Chinese Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

    abstract:CONTEXT:Limited studies have identified symptom clusters (SCs) and their risk factors and the relationships with inflammatory biomarkers in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). OBJECTIVES:In this study, we aimed to investigate SCs in patients with AECOPD and explore their...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2020.03.037

    authors: Yang Z,Cui M,Zhang X,Bai J,Tang L,Tan G,Jiang Y

    更新日期:2020-09-01 00:00:00

  • Postoperative analgesics for children and adolescents: prescription and administration.

    abstract::Pain was measured and analgesic treatment examined in 131 children and adolescents, 8-17 years of age, for 5 days after surgery. Analgesic data were converted to 10 mg intramuscular morphine-equivalent doses (IMMSEQ) and were designated appropriate or inappropriate for body weight. Analgesic onset, peak, and duration ...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/0885-3924(94)90161-9

    authors: Tesler MD,Wilkie DJ,Holzemer WL,Savedra MC

    更新日期:1994-02-01 00:00:00

  • Outpatient pain predicts subsequent one-year acute health care utilization among adults with sickle cell disease.

    abstract:CONTEXT:Patient demographic and clinical factors have known associations with acute health care utilization (AHCU) among patients with sickle cell disease (SCD), but it is unknown if pain measured predominantly in an outpatient setting is a predictor of future AHCU in patients with SCD. OBJECTIVES:To determine whether...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2013.08.020

    authors: Ezenwa MO,Molokie RE,Wang ZJ,Yao Y,Suarez ML,Angulo V,Wilkie DJ

    更新日期:2014-07-01 00:00:00

  • Validation of the Family Inpatient Communication Survey.

    abstract:CONTEXT:Although many family members who make surrogate decisions report problems with communication, there is no validated instrument to accurately measure surrogate/clinician communication for older adults in the acute hospital setting. OBJECTIVES:The objective of this study was to validate a survey of surrogate-rat...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2016.08.010

    authors: Torke AM,Monahan P,Callahan CM,Helft PR,Sachs GA,Wocial LD,Slaven JE,Montz K,Inger L,Burke ES

    更新日期:2017-01-01 00:00:00

  • Barriers to effective symptom management in hospice.

    abstract::The barriers to effective symptom management in hospice are not well described. We surveyed nurses of hospices affiliated with the Population-based Palliative Care Research Network (PoPCRN) to identify barriers to the effective management of common symptoms in terminally ill patients. 867/1710 (51%) nurses from 67 hos...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2004.09.001

    authors: Johnson DC,Kassner CT,Houser J,Kutner JS

    更新日期:2005-01-01 00:00:00

  • Hospital mortality rates: how is palliative care taken into account?

    abstract:CONTEXT:Using mortality rates to measure hospital quality presumes that hospital deaths are medical failures. To be a fair measure of hospital quality, hospital mortality measures must take patient-level factors, such as goals of care, into account. OBJECTIVES:To answer questions about how hospital mortality rates are...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2010.07.005

    authors: Cassel JB,Jones AB,Meier DE,Smith TJ,Spragens LH,Weissman D

    更新日期:2010-12-01 00:00:00

  • Pain in amaXhosa Women Living With HIV/AIDS: Translation and Validation of the Brief Pain Inventory-Xhosa.

    abstract:CONTEXT:Pain has been reported as the second most commonly reported symptom in people living with HIV/AIDS. In South Africa, there are more than five million people living with HIV/AIDS. Approximately, two million belong to the Xhosa cultural group. The prevalence of pain in amaXhosa living with HIV/AIDS was unknown at...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2015.08.004

    authors: Parker R,Jelsma J,Stein DJ

    更新日期:2016-01-01 00:00:00

  • Perceptions of specialized inpatient palliative care: a population-based survey in Japan.

    abstract::This study aimed to clarify and compare the awareness and perceptions of the specialized inpatient palliative care service. A cross-sectional questionnaire survey was performed on the general population selected by stratified two-stage random sampling (n=2,548) and bereaved families who actually received specialized i...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2007.04.021

    authors: Sanjo M,Miyashita M,Morita T,Hirai K,Kawa M,Ashiya T,Ishihara T,Miyoshi I,Matsubara T,Nakaho T,Nakashima N,Onishi H,Ozawa T,Suenaga K,Tajima T,Hisanaga T,Uchitomi Y

    更新日期:2008-03-01 00:00:00

  • The Family Caregiving Crisis Meets an Actual Pandemic.

    abstract::The coronavirus disease 2019 (COVID-19) pandemic presents unique challenges to those who work with the seriously ill population, including both health care providers and the family caregivers providing unpaid care. We rely on this lay workforce as health care routinely transitions care to the home, and now more than e...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2020.04.006

    authors: Kent EE,Ornstein KA,Dionne-Odom JN

    更新日期:2020-07-01 00:00:00

  • Caregiver Expectations: Predictors of a Worse Than Expected Caregiving Experience at the End of Life.

    abstract:CONTEXT:The gap between informal caregivers' expectations of caregiving at the end of life and their actual caregiving experience has important affective and behavioral consequences. OBJECTIVES:This study analyzes for the first time the characteristics of those caregivers who report a worse or much worse than expected...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2015.04.017

    authors: Burns EJ,Quinn SJ,Abernethy AP,Currow DC

    更新日期:2015-10-01 00:00:00

  • Cancer Treatment Side Effects: A Meta-analysis of the Relationship Between Response Expectancies and Experience.

    abstract:CONTEXT:Although previous research has, overall, suggested a moderate relationship between response expectancies (REs) and cancer treatment-related side effects, empirical results have been mixed. OBJECTIVES:We aimed to further explore these relationships, hypothesizing that REs would predict subsequent toxicities wit...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jpainsymman.2017.03.017

    authors: Devlin EJ,Denson LA,Whitford HS

    更新日期:2017-08-01 00:00:00

  • Pain scores in infants: a modified infant pain scale versus visual analogue.

    abstract::This study describes an observational system (modified infant pain scale, MIPS) with elements from a previously published observational scale and from assessments of video-recorded infant facial expressions. It was designed to allow rapid and repeated assessments of pain in infants after brief training by an observer ...

    journal_title:Journal of pain and symptom management

    pub_type: 临床试验,杂志文章

    doi:

    authors: Buchholz M,Karl HW,Pomietto M,Lynn A

    更新日期:1998-02-01 00:00:00

  • Improving cancer pain management in communities: main results from a randomized controlled trial.

    abstract::The purpose of this randomized controlled community trial is to evaluate the effects of a community intervention utilizing opinion leaders and educational strategies on the cancer pain management knowledge, attitudes, and the practices of physicians and nurses, and cancer pain reported by patients. Six Minnesota commu...

    journal_title:Journal of pain and symptom management

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0885-3924(96)00275-8

    authors: Elliott TE,Murray DM,Oken MM,Johnson KM,Braun BL,Elliott BA,Post-White J

    更新日期:1997-04-01 00:00:00

  • Can just-in-time, evidence-based "reminders" improve pain management among home health care nurses and their patients?

    abstract::The purpose of this randomized, controlled, home care intervention was to test the effectiveness of two nurse-targeted, e-mail-based interventions to increase home care nurses' adherence to pain assessment and management guidelines, and to improve patient outcomes. Nurses from a large urban non-profit home care organi...

    journal_title:Journal of pain and symptom management

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.jpainsymman.2004.08.018

    authors: McDonald MV,Pezzin LE,Feldman PH,Murtaugh CM,Peng TR

    更新日期:2005-05-01 00:00:00

  • Opioid Concentrations in Oral Fluid and Plasma in Cancer Patients With Pain.

    abstract:CONTEXT:Measuring opioid concentrations in pain treatment is warranted in situations where optimal opioid analgesia is difficult to reach. OBJECTIVES:To assess the usefulness of oral fluid (OFL) as an alternative to plasma in opioid concentration monitoring in cancer patients on chronic opioid therapy. METHODS:We col...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章

    doi:10.1016/j.jpainsymman.2014.09.004

    authors: Heiskanen T,Langel K,Gunnar T,Lillsunde P,Kalso EA

    更新日期:2015-10-01 00:00:00

  • Spiritual Needs and Perception of Quality of Care and Satisfaction With Care in Hematology/Medical Oncology Patients: A Multicultural Assessment.

    abstract:CONTEXT:Assessment and response to patients' spiritual concerns are crucial components of high-quality supportive care. Better measures of spiritual needs across the cultural spectrum may help direct necessary interventions. OBJECTIVES:The objective of this study was to assess spiritual needs in a racially/ethnically ...

    journal_title:Journal of pain and symptom management

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jpainsymman.2017.08.009

    authors: Astrow AB,Kwok G,Sharma RK,Fromer N,Sulmasy DP

    更新日期:2018-01-01 00:00:00