Plasma HDL cholesterol, triglycerides, and adiposity. A quantitative genetic test of the conjoint trait hypothesis in the San Antonio Family Heart Study.

abstract：BACKGROUND:The use of molecular biological techniques has demonstrated the importance of enteroviral infection of the myocardium in the pathogenesis of myocarditis and dilated cardiomyopathy in adults and adenovirus and enterovirus infection in children. The aim of this study was to determine the frequency of adenovira...

journal_title：Circulation

authors： Pauschinger M,Bowles NE,Fuentes-Garcia FJ,Pham V,Kühl U,Schwimmbeck PL,Schultheiss HP,Towbin JA

更新日期：1999-03-16 00:00:00

abstract：BACKGROUND:New methods of R-R interval variability based on fractal scaling and nonlinear dynamics ("chaos theory") may give new insights into heart rate dynamics. The aims of this study were to (1) systematically characterize and quantify the effects of aging from early childhood to advanced age on 24-hour heart rate ...

journal_title：Circulation

authors： Pikkujämsä SM,Mäkikallio TH,Sourander LB,Räihä IJ,Puukka P,Skyttä J,Peng CK,Goldberger AL,Huikuri HV

更新日期：1999-07-27 00:00:00

abstract：:One hundred eighteen consecutive patients undergoing valve replacement for aortic stenosis were analyzed to determine the incidence of and predisposing factors to postoperative atrial tachyarrhythmias. Univariate and multivariate analyses were performed on 70 clinical, hemodynamic, radiographic, electrocardiographic, ...

journal_title：Circulation

authors： Douglas PS,Hirshfeld JW Jr,Edmunds LH Jr

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Myocardial necrosis can occur during percutaneous coronary intervention (PCI) despite optimal adjunctive pharmacology and careful technique. We investigated the mechanisms of procedural infarction using angiographic analysis, intravascular ultrasound, and delayed-enhancement magnetic resonance imaging. METH...

journal_title：Circulation

authors： Porto I,Selvanayagam JB,Van Gaal WJ,Prati F,Cheng A,Channon K,Neubauer S,Banning AP

更新日期：2006-08-15 00:00:00

abstract：BACKGROUND:The impact of mitral regurgitation (MR) on elderly patients (> or = 70 years) undergoing isolated aortic valve replacement (AVR) is not clearly defined. This study investigates the long-term effects of preoperative, moderate MR on survival and functional outcome in elderly AVR patients. METHODS AND RESULTS:...

journal_title：Circulation

authors： Barreiro CJ,Patel ND,Fitton TP,Williams JA,Bonde PN,Chan V,Alejo DE,Gott VL,Baumgartner WA

更新日期：2005-08-30 00:00:00

abstract：BACKGROUND:Myocardium irreversibly injured by ischemic stress must be efficiently repaired to maintain tissue integrity and contractile performance. Macrophages play critical roles in this process. These cells transform across a spectrum of phenotypes to accomplish diverse functions ranging from mediating the initial i...

journal_title：Circulation

authors： Cao DJ,Schiattarella GG,Villalobos E,Jiang N,May HI,Li T,Chen ZJ,Gillette TG,Hill JA

更新日期：2018-06-12 00:00:00

abstract：BACKGROUND:Long-term survival after acute kidney injury (AKI) is poorly studied. We report the relationship between long-term mortality and AKI with small changes in serum creatinine during hospitalization after various cardiothoracic surgery procedures. METHODS AND RESULTS:This was a retrospective study of 2973 patie...

journal_title：Circulation

authors： Hobson CE,Yavas S,Segal MS,Schold JD,Tribble CG,Layon AJ,Bihorac A

更新日期：2009-05-12 00:00:00

abstract：:Body surface isochrone mapping was performed in 36 normal subjects and in 85 patients with previous myocardial infarction. Eighty-seven unipolar electrocardiograms distributed over the anterior chest and the back were recorded simultaneously. For each lead, activation time was measured as the time from the onset of QR...

journal_title：Circulation

authors： Ikeda K,Kubota I,Igarashi A,Yamaki M,Tsuiki K,Yasui S

更新日期：1985-10-01 00:00:00

abstract：:An isolated perfused working rat heart model was used to investigate the extent to which various protective agents, used either singly or in combination, were able to increase the resistance of the heart to periods of transient ischemia. The aim of the studies was to develop a solution which, if infused into the coron...

journal_title：Circulation

authors： Hearse DJ,Stewart DA,Braimbridge MV

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Estrogen may increase the long-term survival of women who have suffered from a myocardial infarction (MI). We examined the acute and chronic influence of estrogen on MI in the rat left coronary artery ligation model. METHODS AND RESULTS:Female Sprague-Dawley rats (10 to 12 weeks, n=93), divided into 3 group...

journal_title：Circulation

authors： Smith PJ,Ornatsky O,Stewart DJ,Picard P,Dawood F,Wen WH,Liu PP,Webb DJ,Monge JC

更新日期：2000-12-12 00:00:00

abstract：:Purine compounds modulate sympathetic neurotransmission; this modulation decreases nervous discharge by stimulating presynaptic inhibitory adenosine receptors, an effect antagonized by theophylline, and causes vasoconstriction through the stimulation of postsynaptic ATP receptors. In humans we evaluated the effect of ...

journal_title：Circulation

authors： Taddei S,Pedrinelli R,Salvetti A

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:The influence of changes in heart rate on myocardial contractility (the force-frequency effect) differs under various experimental conditions, including the anesthetized versus the conscious state. METHODS AND RESULTS:To assess the influence of beta-adrenergic stimulation on force-frequency effects on myoca...

journal_title：Circulation

authors： Kambayashi M,Miura T,Oh BH,Rockman HA,Murata K,Ross J Jr

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:No information is available on the long-term results of radial artery (RA) grafts used as coronary artery bypass conduits. METHODS AND RESULTS:In this report, we describe the long-term (105+/-9 months) angiographic results of a series of 90 consecutive patients in whom the RA was used as a coronary artery b...

journal_title：Circulation

authors： Possati G,Gaudino M,Prati F,Alessandrini F,Trani C,Glieca F,Mazzari MA,Luciani N,Schiavoni G

更新日期：2003-09-16 00:00:00

abstract：:Platelets have been implicated in the pathogenesis of coronary artery disease, and a number of studies have examined platelet function and coagulation parameters in such patients. We have examined platelet coagulant activities, volumes, and aggregate ratios in 23 patients with chest pain, seven of whom had normal coro...

journal_title：Circulation

authors： Rao AK,Mintz PD,Lavine SJ,Bove AA,McDonough MT,Spann JF,Walsh PN

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Functional benefit in heart failure due to idiopathic dilated cardiomyopathy has been observed after beta-blockade, but improvement in survival has not been established in a large-scale randomized trial. This was the main objective of the Cardiac Insufficiency Bisoprolol Study (CIBIS). METHODS AND RESULTS:S...

journal_title：Circulation

authors：

更新日期：1994-10-01 00:00:00

abstract：:This article provides a selective overview of epidemiologic studies on the relationship between psychosocial factors and blood pressure elevation. The review focuses on English-language reports published since 1975 and emphasizes two broad areas of research: changes in mean blood pressures of third world populations u...

journal_title：Circulation

authors： James SA

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Activation of the sympathetic nervous system has important prognostic implications in chronic heart failure. Nonselective versus selective beta-adrenergic receptor antagonists may have differential effects on norepinephrine release from nerve terminals mediated by prejunctional beta(2)-adrenergic receptors. ...

journal_title：Circulation

authors： Azevedo ER,Kubo T,Mak S,Al-Hesayen A,Schofield A,Allan R,Kelly S,Newton GE,Floras JS,Parker JD

更新日期：2001-10-30 00:00:00

abstract：BACKGROUND:Alterations in myocardial function and systemic vascular tone are well documented in congestive heart failure (CHF), but little information is available on the effects of CHF on pulmonary vessels. We examined the mechanisms of tone regulation of canine pulmonary arteries during pacing-induced CHF. METHODS A...

journal_title：Circulation

authors： Mathew R,Wang J,Gewitz MH,Hintze TH,Wolin MS

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Although diabetes confers an increased propensity toward accelerated atherogenesis, data are lacking on monocyte activity in type 2 diabetic patients with (DM2-MV) and without (DM2) macrovascular disease compared with control subjects. Thus, we tested whether (1) postsecretory modifications of LDL (glycation...

journal_title：Circulation

authors： Devaraj S,Jialal I

更新日期：2000-07-11 00:00:00

abstract：BACKGROUND:The number of CD4(+)CD28(null) (CD28(null)) T cells, a unique subset of T lymphocytes with proinflammatory and cell-lytic phenotype, increases markedly in patients with acute coronary syndrome (ACS). ACS patients harboring high numbers of CD28(null) T cells have increased risk of recurrent severe acute coron...

journal_title：Circulation

authors： Kovalcsik E,Antunes RF,Baruah P,Kaski JC,Dumitriu IE

更新日期：2015-02-24 00:00:00

abstract：:Two hundred twenty-nine hospital survivors of acute myocardial infarction (MI) age 60 years or younger underwent coronary arteriography a median of 2 weeks after infarction and were followed a median of 24 months (range 6-62 months). For 62%, MI was the first presentation of coronary disease and 75% were in clinical K...

journal_title：Circulation

authors： Roubin GS,Harris PJ,Bernstein L,Kelly DT

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:During ischemia, the intracellular calcium and inorganic phosphate (P(i)) concentrations rise and pH falls. We investigated the effects of these changes on force development in donor and failing human hearts to determine if altered contractile protein composition during heart failure changes the myocardial r...

journal_title：Circulation

authors： van Der Velden J,Klein LJ,Zaremba R,Boontje NM,Huybregts MA,Stooker W,Eijsman L,de Jong JW,Visser CA,Visser FC,Stienen GJ

更新日期：2001-09-04 00:00:00

abstract：:Electrophysiologic effects of 50 mg iv ajmaline were evaluated in 10 patients with atrioventricular nodal reentrant paroxysmal supraventricular tachycardia (PSVT) utilizing the slow pathway for antegrade and the fast pathway for retrograde conduction. Ajmaline terminated the PSVT in all 10 patients in 17 to 165 sec (m...

journal_title：Circulation

authors： Sethi KK,Jaishankar S,Gupta MP

更新日期：1984-11-01 00:00:00

abstract：:The pericardium, because of the nature of its pressure-volume relation, can influence left ventricular diastolic and systolic pump function. During an acute increase in heart size that results in the stretching of the pericardium, the elastic properties of the pericardium restrict further cardiac dilatation and curtai...

journal_title：Circulation

authors： Janicki JS

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Intraoperative mapping studies suggest that an isthmus of myocardium between the mitral valve annulus and the border of inferior myocardial infarction may play a role in the genesis of ventricular tachycardia. We examined the frequency with which a slow conduction zone within the mitral isthmus was critical ...

journal_title：Circulation

authors： Wilber DJ,Kopp DE,Glascock DN,Kinder CA,Kall JG

更新日期：1995-12-15 00:00:00

abstract：BACKGROUND:Although dyslipoproteinemia is associated with arterial atherothrombosis, little is known about plasma lipoproteins in venous thrombosis patients. METHODS AND RESULTS:We determined plasma lipoprotein subclass concentrations using nuclear magnetic resonance spectroscopy and antigenic levels of apolipoprotein...

journal_title：Circulation

authors： Deguchi H,Pecheniuk NM,Elias DJ,Averell PM,Griffin JH

更新日期：2005-08-09 00:00:00

abstract：:To determine whether real-time two-dimensional echocardiography (2-D echo) can estimate the extent of myocardial involvement in patients with acute myocardial infarction (MI), regional wall motion on serial short-axis 2-D echo recordings was analyzed and the summed scores were compared with estimates of infarct involv...

journal_title：Circulation

authors： Nixon JV,Narahara KA,Smitherman TC

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Performance of coronary artery bypass graft (CABG) during an acute coronary syndrome (ACS) is mainly used in high-risk patients. Although potentially life-saving, patients undergoing early CABG are traditionally associated with a worse outcome than those not requiring CABG. Is this really true in an unselect...

journal_title：Circulation

authors： Monteiro P,Portuguese Registry on Acute Coronary Syndromes.

更新日期：2006-07-04 00:00:00

abstract：BACKGROUND:Low endothelial shear stress (ESS) promotes the development of atherosclerosis; however, its role in the progression of atherosclerotic plaques and evolution to inflamed high-risk plaques has not been studied. Our hypothesis was that the lowest values of ESS are responsible for the development of high-risk c...

journal_title：Circulation

authors： Chatzizisis YS,Jonas M,Coskun AU,Beigel R,Stone BV,Maynard C,Gerrity RG,Daley W,Rogers C,Edelman ER,Feldman CL,Stone PH

更新日期：2008-02-26 00:00:00

abstract：:While the steady-state effects of positive pleural pressure on the circulation have been extensively studied, less is known about the immediate effects of positive intrathoracic pressure on cardiac dynamics. Therefore, we performed electrocardiographically gated radionuclide ventriculography with a respiratory gating ...

journal_title：Circulation

authors： Natarajan TK,Wise RA,Karam M,Permutt S,Wagner HN Jr

更新日期：1987-01-01 00:00:00