Regulation of NIH-3T3 cell G1 phase transit by serum during exponential growth.

abstract：OBJECTIVES:Bone marrow edema is a universal manifestation of rheumatoid arthritis (RA), and its pathological essence is a bone marrow lesion (BML) formed by various bone marrow (BM) immune cells. Neutrophils play an important role in inflammatory arthritis, but the role and mechanism of neutrophils in BML are not clear...

journal_title：Cell proliferation

authors： Xu D,Lin Y,Shen J,Zhang J,Wang J,Zhang Y,Zhang H,Ning L,Liu P,Li S,Zeng H,Lin J,Yu C

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:It has been widely reported that maternal diabetes impairs oocyte quality. However, the responsible mechanisms remain to be explored. In the present study, we focused on whether SIRT3-GSK3β pathway mediates the meiotic defects in oocytes from diabetic mice. MATERIALS AND METHODS:GSK3β functions in mouse ooc...

journal_title：Cell proliferation

authors： Xin Y,Jin Y,Ge J,Huang Z,Han L,Li C,Wang D,Zhu S,Wang Q

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Serum is usually added to growth media when mammalian cells are cultured in vitro to supply the cells with growth factors, hormones, nutrients and trace elements. Defined proteins and metal ions, such as insulin, growth factors, transferrin and sodium selenite, are sometimes also included and can in some case...

journal_title：Cell proliferation

authors： Zander L,Bemark M

更新日期：2008-02-01 00:00:00

abstract：:On 31 May 2010, 14 072 567 bone marrow/apheresis donors registered in 44 countries and 426 501 cord blood units banked in 26 countries for public use were available to treat candidates to haemopoietic stem cell transplant lacking a family related compatible donor. Despite these impressive numbers, additional efforts a...

journal_title：Cell proliferation

authors： Rebulla P,Lecchi L

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:In this study, we generated an Rbm14 knockout mouse model to explore its functions during early mouse embryogenesis. MATERIALS AND METHODS:The Rbm14 knockout mouse model was generated by a combination of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 and microinjection techniques. Th...

journal_title：Cell proliferation

authors： Li J,Wang C,Feng G,Zhang L,Chen G,Sun H,Wang J,Zhang Y,Zhou Q,Li W

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:miRNAs play crucial roles in human tumourigenesis. This study was performed to measure expression and function of miR-762 in breast cancer. MATERIALS AND METHODS:Expression of miR-762 in breast tissues and cell lines (SK-BR-3, DA-MB-435s, MCF-7 and MDA-MB-231, HBL-100) was measured by using real-time RT-PCR...

journal_title：Cell proliferation

authors： Li Y,Huang R,Wang L,Hao J,Zhang Q,Ling R,Yun J

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:Oral cancer represents one of the most common malignancies in humans. Its prognosis is still poor, despite the most recent improvements in therapies. An increasing attention is placed on the role of programmed death ligand 1 (PD-L1) in the tumour immunity and its potential function as a marker for tumour pro...

journal_title：Cell proliferation

authors： Troiano G,Caponio VCA,Zhurakivska K,Arena C,Pannone G,Mascitti M,Santarelli A,Lo Muzio L

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Curcumin, a natural compound, is a potent anti-cancer agent, which inhibits cell division and/or induces cell death. It is believed that normal cells are less sensitive to curcumin than malignant cells; however, the mechanism(s) responsible for curcumin's effect on normal cells are poorly understood. The aim...

journal_title：Cell proliferation

authors： Bielak-Zmijewska A,Sikora-Polaczek M,Nieznanski K,Mosieniak G,Kolano A,Maleszewski M,Styrna J,Sikora E

更新日期：2010-08-01 00:00:00

abstract：:Aberrant crypt foci (ACF) have been identified on the colonic mucosal surface of rodents treated with colon carcinogens and of humans after methylene-blue staining and observation under a light microscope. Several lines of evidence strongly suggest that ACF with certain morphological, histological, cell kinetics, and ...

journal_title：Cell proliferation

authors： Roncucci L,Pedroni M,Vaccina F,Benatti P,Marzona L,De Pol A

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:To assess the expression, prognostic value, and functionality of T-lymphokine-activated killer (T-LAK) cell-originated protein kinase (TOPK) in chordoma pathogenesis. MATERIALS AND METHODS:TOPK expression in chordoma was assessed via immunohistochemical staining of a tissue microarray (TMA) and correlated w...

journal_title：Cell proliferation

authors： Thanindratarn P,Dean DC,Nelson SD,Hornicek FJ,Duan Z

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Panax ginseng, a well-known traditional Chinese medicine with multiple pharmacological activities, plays a crucial role in modulating mood disorders. Several recent studies have identified an underlying role of Panax ginseng in the prevention and treatment of depression. However, the cellular and molecular m...

journal_title：Cell proliferation

authors： Jin Y,Cui R,Zhao L,Fan J,Li B

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:In order to provide a more comprehensive understanding of the effects of SARS-CoV-2 on oral health and possible saliva transmission, we performed RNA-seq profiles analysis from public databases and also a questionnaire survey on oral-related symptoms of COVID-19 patients. MATERIALS AND METHODS:To analyse AC...

journal_title：Cell proliferation

authors： Chen L,Zhao J,Peng J,Li X,Deng X,Geng Z,Shen Z,Guo F,Zhang Q,Jin Y,Wang L,Wang S

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:High mobility group protein2 (HMGA2) and epithelial-to-mesenchymal transition are both related to progress of bladder cancer, however, the relationship between HMGA2, E-cadherin and vimentin in bladder cancer is not yet known. Thus, this study has examined expression of HMGA2, E-cadherin and vimentin in blad...

journal_title：Cell proliferation

authors： Ding X,Wang Y,Ma X,Guo H,Yan X,Chi Q,Li J,Hou Y,Wang C

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:Limbal stem cells (LSC) are self-renewing, highly proliferative cells in vitro, which express a set of specific markers and in vivo have the capacity to reconstruct the entire corneal epithelium in cases of ocular surface injury. Currently, LSC transplantation is a commonly used procedure in patients with ei...

journal_title：Cell proliferation

authors： Monteiro BG,Serafim RC,Melo GB,Silva MC,Lizier NF,Maranduba CM,Smith RL,Kerkis A,Cerruti H,Gomes JA,Kerkis I

更新日期：2009-10-01 00:00:00

abstract：:In situ presence of numerous DNA strand breaks is a typical feature of apoptotic cells. Selective DNA strand break induction by photolysis (SBIP) at sites that contain incorporated halogenated DNA precursors has recently been proposed as a method of analysing DNA replication. Detection of DNA strand breaks, thus, enab...

journal_title：Cell proliferation

authors： Li X,Darzynkiewicz Z

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:Silicate bioactive glass (BG) has been widely demonstrated to stimulate both of the hard and soft tissue regeneration, in which ion products released from BG play important roles. However, the mechanism by which ion products act on cells on cells is unclear. MATERIALS AND METHODS:Human umbilical vein endoth...

journal_title：Cell proliferation

authors： Yan L,Li H,Xia W

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Often, non-small cell lung cancers (NSCLC) respond only poorly to the tyrosine kinase inhibitor (TKI) gefitinib, which targets the epidermal growth factor receptor (EGFR), these poor responders EGFRs lacking activating mutations. In this study, we have attempted to improve TKI response of NSCLC cell lines (A...

journal_title：Cell proliferation

authors： Postiglione I,Chiaviello A,Aloj SM,Palumbo G

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:Dental follicle cells (DFCs) provide the origin of periodontal tissues, and Runx2 is essential for bone formation and tooth development. In this study, pluripotency of DFCs was evaluated and effects of Runx2 on them were investigated. MATERIALS AND METHODS:The DFCs were induced to differentiate towards oste...

journal_title：Cell proliferation

authors： Pan K,Sun Q,Zhang J,Ge S,Li S,Zhao Y,Yang P

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Spinal cord tumours are highly malignant and often lead to paralysis and death due to their infiltrative nature, high recurrence rate and limited treatment options. In this study, we measured antitumour efficacy of the Salmonella typhimurium A1-R tumour-targeting bacterium strain, administered systemically or...

journal_title：Cell proliferation

authors： Kimura H,Zhang L,Zhao M,Hayashi K,Tsuchiya H,Tomita K,Bouvet M,Wessels J,Hoffman RM

更新日期：2010-02-01 00:00:00

abstract：:This study focuses on analysis of in vitro cultures of chondrocytes from ovine articular cartilage. Isolated cells were seeded in Petri dishes, then expanded to confluence and phenotypically characterized by flow cytometry. The sigmoidal temporal profile of total counts was obtained by classic haemocytometry and corre...

journal_title：Cell proliferation

authors： Mancuso L,Liuzzo MI,Fadda S,Pisu M,Cincotti A,Arras M,La Nasa G,Concas A,Cao G

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:Vascular disorders are associated with phenotypical switching of vascular smooth muscle cells (VSMCs). We investigated the effect of bone morphogenetic protein (BMP)-2 in controlling VSMC phenotype and vascular disorder progression. Lysine (K)-specific demethylase 1A (KDM1A) has been identified to target BMP...

journal_title：Cell proliferation

authors： Zhang X,Huang T,Zhai H,Peng W,Zhou Y,Li Q,Yang H

更新日期：2020-01-01 00:00:00

abstract：:Extracellular vesicles (EVs), a heterogeneous group of vesicles differing in size and shape, cargo content and function, are membrane-bound and nano-sized vesicles that could be released by nearly all variations of cells. EVs have gained considerable attention in the past decades for their functions in modulating inte...

journal_title：Cell proliferation

authors： Wu Z,Zhang Z,Xia W,Cai J,Li Y,Wu S

更新日期：2019-11-01 00:00:00

abstract：:The prostate gland is the site of the most commonly diagnosed cancer in men in USA and UK, accounting for one in five of new cases of male cancer. Common with many other cancer types, prostate cancer is believed to arise from a stem cell that shares characteristics with the normal stem cell. Normal prostate epithelial...

journal_title：Cell proliferation

authors： Rizzo S,Attard G,Hudson DL

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:Recent data show that Imatinib mesylate (IM) also affects haematopoietic stem cells (HSC), T lymphocytes and dendritic cells that do not harbour constitutively active tyrosine kinases. MATERIALS AND METHODS:We evaluated possible effects of IM on human bone marrow-derived mesenchymal stem cells (MSC) in vitr...

journal_title：Cell proliferation

authors： Fierro F,Illmer T,Jing D,Schleyer E,Ehninger G,Boxberger S,Bornhäuser M

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:Osteopetrosis is a rare inherited skeletal disease characterized by increased bone mineral density due to the loss of osteoclast function or differentiation potential. MATERIALS AND METHODS:The study involved a Chinese patient with osteopetrosis (the proband) and her immediate family members and 180 control...

journal_title：Cell proliferation

authors： Yuan Y,Yang L,Liu T,Zhang H,Lu Q

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:To evaluate the rapid repair potential of adipose-derived stem cells (ADSCs) co-overexpressing VEGF and GDNF on bilateral cavernous nerve injury (BCNI) in rat models. Progressive fibrosis of the penis that occurs shortly after BCNI is a key cause of clinical treatment difficulty of erectile dysfunction (ED)....

journal_title：Cell proliferation

authors： Yang W,Chen Z,Ma X,Ouyang X,Fang J,Wei H

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Intracellular reactive oxygen species (ROS) induced by receptor activator of NF-kB ligand (RANKL) has been proven to be a critical factor in the development of osteoclasts. This study aimed to prove that schisandrin A (Sch), a novel anti-oxidant compound, is able to suppress osteoclastogenesis and prevent bo...

journal_title：Cell proliferation

authors： Ni S,Qian Z,Yuan Y,Li D,Zhong Z,Ghorbani F,Zhang X,Zhang F,Zhang Z,Liu Z,Yu B

更新日期：2020-10-01 00:00:00

abstract：:Natural compounds derived from plant sources are well characterized as possessing a wide variety of remarkable anti-tumour properties, for example modulating programmed cell death, primarily referring to apoptosis, and autophagy. Distinct from apoptosis, autophagy (an evolutionarily conserved, multi-step lysosomal deg...

journal_title：Cell proliferation

authors： Zhang X,Chen LX,Ouyang L,Cheng Y,Liu B

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:This study is to explore the role of Notch signalling during the regeneration of rat tracheal epithelium after injury induced by 5-fluorouracil (5-FU). MATERIALS AND METHODS:We developed an ex vivo model of rat tracheal epithelial regeneration using 5-FU to induce injury. Expression levels of members of the...

journal_title：Cell proliferation

authors： Ma XB,Jia XS,Liu YL,Wang LL,Sun SL,Song N,Wang EH,Li F

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:The present study aimed to investigate overall effect of quercetin on proliferation and osteogenic differentiation of mouse adipose stem cells (mASCs) in vitro. MATERIALS AND METHODS:Mouse adipose stem cells were isolated from subcutaneous fat pads and induced into the osteogenic lineage. Effects of quercet...

journal_title：Cell proliferation

authors： Zhou C,Lin Y

更新日期：2014-04-01 00:00:00