Abstract:
OBJECTIVES:To evaluate three urine markers, BTA stat, cytology, and urinary survivin levels, in the spinal cord injury (SCI) population. The incidence of bladder cancer in patients with SCI is up to 20 times greater than in the general population. However, bladder cancer biomarkers have not been assessed in this population. METHODS:Between April 1999 and April 2004, 457 patients with SCI enrolled at the HealthSouth Harmarville Rehabilitation Spinal Cord Clinic donated their urine to our SCI urine repository. BTA stat tests and the survivin assay were performed according to published standards. Cytology specimens were sent to our cytopathology laboratory for analysis. RESULTS:A total of 1075 urine specimens from 457 patients were analyzed. Of the 1073 BTA stat tests, 119 showed positive reactions and 954 were negative. In the survivin assays, 47 samples had a score of 1, 38 a score of 2, and 9 a score of 3. No cytology specimens were noted to have malignant cells. During the past 5 years, 3 patients were diagnosed with bladder cancer by cystoscopy and treated for superficial disease. For these patients, none of these three tests (BTA stat, survivin assay, and cytology) was positive before the diagnosis of bladder cancer. CONCLUSIONS:The BTA stat, survivin assay, and urine cytology were unable to predict bladder cancer cases in our cohort of patients with SCI. Cystoscopy, therefore, remains the gold standard for bladder cancer surveillance in patients with SCI.
journal_name
Urologyjournal_title
Urologyauthors
Davies B,Chen JJ,McMurry T,Landsittel D,Lewis N,Brenes G,Getzenberg RHdoi
10.1016/j.urology.2005.05.022subject
Has Abstractpub_date
2005-10-01 00:00:00pages
908-11issue
4eissn
0090-4295issn
1527-9995pii
S0090-4295(05)00687-4journal_volume
66pub_type
杂志文章相关文献
UROLOGY文献大全abstract:OBJECTIVE:To evaluate feasibility of percutaneous nephrolithotomy (PCNL) for complex nephrolithiasis in patients 80 years of age and older compared to younger individuals. METHODS:From an institutional IRB-approved database, 1,647 patients were identified who underwent PCNL from 1999 to 2019. Patients were stratified ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2019.08.044
更新日期:2019-12-01 00:00:00
abstract::In the presence of unsuspected extensive perirenal and pararenal disease, renal calculus surgery may be associated with extensive morbidity and mortality. To plan surgery properly, computed tomography (CT) often can be essential preoperatively. Three cases are presented where CT readily demonstrated the degree of extr...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(84)90432-1
更新日期:1984-08-01 00:00:00
abstract:OBJECTIVE:To explore whether socioeconomic status (SES) was associated with health-related quality of life (HRQL) and health care use among long-term prostate cancer survivors. PATIENTS AND METHODS:Through urologists in the Comprehensive Cancer Center South, all 5- to 10-year prostate cancer survivors known in the Ein...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.06.013
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the evolving role of gender in invited authorship and editorial positions in the Journal of Pediatric Urology. MATERIALS AND METHODS:We recorded editorial board members and first and senior authors for all editorials and invited commentaries for all issues of the Journal of Pediatric Urology from...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.05.097
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:The combined use of total prostate-specific antigen (PSA), clinical stage, and Gleason score accurately predicts final pathologic stage for men with clinically localized prostate cancer. Recently, the free/ total PSA ratio has been proposed as an adjunct for early detection of prostate cancer. We examined th...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(96)00610-3
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVES:To define the likelihood of nitrate users wishing to use sildenafil citrate being permitted by their nitrate-prescribing physicians to cease nitrate use, and to attempt to derive predictors of a "no" response to this request. METHODS:A total of 248 patients with erectile dysfunction were included in this st...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.01.029
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVES:To investigate clinical features of Chinese patients with severe primary erectile dysfunction (S-PED) and to identify the ideal treatment options for this population. METHODS:Patients with PED were screened for enrollment in our study. Sexual history, marital status, and erectile function were evaluated by ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.12.008
更新日期:2010-08-01 00:00:00
abstract::The functional sequelae of 131 patients with urogenital tuberculosis were examined. At the time of diagnosis, more than half of the patients already suffered from global renal failure which was moderate in 42.7 per cent and severe in 15.5 per cent. We believe that the primary functional damage occurs at the medullary ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(78)90156-5
更新日期:1978-05-01 00:00:00
abstract::Merkel cell carcinoma is an uncommon cutaneous neoplasm of neuroendocrine origin. We report the case of a 71-year-old man with Merkel cell carcinoma metastases to the prostate and bladder presenting with lower urinary tract obstruction. Efforts should be made to optimize the patient's quality of life with the finding ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2004.03.027
更新日期:2004-07-01 00:00:00
abstract::Fifty-four female patients with persistent or recurrent stress urinary incontinence who underwent between 1 and 9 previously unsuccessful operative procedures were treated with transvaginal mobilization of the urethra and anterior vaginal wall with subsequent modified Pereyra bladder neck suspension. The important poi...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(84)90140-7
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVE:To introduce a grading system (kidney, ureter, and bladder [KUB]) to identify encrusted stents that may require multiple surgeries, multimodal surgery, and operative time > 180 minutes for successful removal. METHODS:One hundred ten retained encrusted ureteral stents were retrospectively scored using the KUB...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.06.050
更新日期:2016-11-01 00:00:00
abstract::For clinical practice and research of overactive bladder syndrome, it is essential to evaluate urgency symptoms in daily life. We have developed a portable patient-activated device to record bladder sensations. This electronic device is pocket-size and light, with five grading buttons and another button for cancellati...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.01.036
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:To ascertain the potential utility of magnetic resonance imaging in providing additional clarification of those solid renal mass lesions identified at routine antenatal ultrasonography in early pregnancy and influencing the management of such lesions. METHODS:We present 7 patients in whom magnetic resonance...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2008.07.050
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To determine the effect of preoperative ureteral stenting on success rates of ureteroscopy (URS) for nephroureterolithiasis. MATERIALS AND METHODS:We retrospectively evaluated patients who underwent URS for nephroureterolithiasis without preoperative indwelling ureteral stents. These patients were matched ac...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2012.06.064
更新日期:2012-12-01 00:00:00
abstract::Robot-assisted laparoscopic radical prostatectomy is one of the treatment options for localized prostate cancer, with an excellent disease control rate. However, these patients can experience late disease recurrence with metastatic dissemination. Peritoneal metastases are an uncommon recurrence site. Here, we discuss ...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2019.11.035
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:To examine, in a post-hoc, integrated analysis, the first-dose success, cumulative success by dose, and maintenance of success among men taking tadalafil. Early treatment success is important to men with erectile dysfunction. METHODS:In five double-blind, placebo-controlled, 12-week studies, men were random...
journal_title:Urology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.urology.2004.05.046
更新日期:2004-10-01 00:00:00
abstract::High-pressure chronic retention (HPCR) is a well-recognized common urological emergency which requires prompt treatment. It usually presents with nocturnal enuresis, a tense and palpable bladder, and symptoms of uraemia from renal failure George et al 1983.1 There have been isolated cases in the literature of HPCR pre...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.04.038
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:To investigate the expression of endothelin-1 (ET-1) and adrenomedullin (ADM) in the renal pelvis, stenotic ureteropelvic junction, and ureter of 20 male Wistar rats with congenital unilateral ureteropelvic junction obstruction; the normal contralateral kidneys served as controls. The molecular pathophysiolo...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2003.07.019
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the feasibility of implementing a diet-based intervention in men with prostate cancer. METHODS:Seventy-four men aged 50 to 80 years with biopsy-proven adenocarcinoma of the prostate were randomized to receive either telephone-based dietary counseling or standardized, written nutritional informat...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.11.050
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:To describe my experience of vaginal mesh extrusion using the monofilament polypropylene transobturator sling, the Mentor ObTape. The Mentor ObTape was the first transobturator sling developed as an alternative to the retropubic commercially available suburethral slings for providing mid-urethral support as ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2005.05.015
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:Androgen ablation with luteinizing hormone-releasing hormone (LHRH) agonists, orchiectomy, or oral estrogens has significant untoward sexual side effects. We evaluated a combination of finasteride and flutamide as potency-sparing androgen ablative therapy (AAT) for advanced adenocarcinoma of the prostate. In...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(97)00091-5
更新日期:1997-06-01 00:00:00
abstract::Evidence relating to the perception and view of patients and physicians on natural orifice transluminal endoscopic surgery (NOTES) and laparoendoscopic single-site surgery (LESS) was scrutinized. A comprehensive literature search was performed through PubMed. A total of 18 studies were included in the analysis. Patien...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2012.04.002
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:To identify patient groups associated with a high probability of false positives in photodynamic diagnosis (PDD) of bladder cancer for which the use of highly specific optical instruments could be beneficial. METHODS:This study includes the data of 306 patients. Under white light and 5-aminolevulinic acid-i...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.04.095
更新日期:2009-10-01 00:00:00
abstract::Pulse granulomas are uncommon, benign foreign body inflammatory reactions that typically occur in the oral cavity. They are exceedingly rare elsewhere. Here we describe a 35-year-old woman who presented with interstitial cystitis and was found to have an incidental bladder mass. Histological examination of the biopsy ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2008.02.013
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To investigate the longitudinal changes in lower urinary tract symptoms (LUTS) after robot-assisted radical prostatectomy (RARP). METHODS:Data on 127 patients who underwent RARP and completed the American Urological Association Symptom Score (AUASS) preoperatively and at 3, 6, and 12 months after surgery wer...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2012.12.038
更新日期:2013-04-01 00:00:00
abstract::Seventeen children who had vesicoureteral reflux underwent urodynamic and rectal manometric studies. All had uninhibited bladder contractions. All had rectal dilatation confirming the presence of constipation by rectal balloon manometry. The recurrent association of constipation with ureteral reflux suggests the possi...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(86)90070-1
更新日期:1986-11-01 00:00:00
abstract:OBJECTIVES:To conduct a preliminary investigation on statin use and its impact on clinical presentation and biochemical progression-free survival after brachytherapy. METHODS:A total of 512 consecutive patients were treated with permanent brachytherapy for clinical Stage T1c-T3aNxM0 prostate cancer at least 3 years be...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2005.08.053
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVES:To investigate, by real-time quantitative reverse transcriptase-polymerase chain reaction, the expression of MUC3 and vascular endothelial growth factor (VEGF) to correlate them with histologic parameters and with prognosis. Human mucins are large O-glycoproteins expressed in epithelial tissues. Deregulation...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(03)00560-0
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:Since the beginning of the 1980s, when gene technology provided sufficient amounts of cytokines, numerous Phase II studies in metastatic renal cell carcinoma were carried out mostly with interferon alfa (IFN-alpha) and interleukin-2 (IL-2). So far, no randomized prospective trials including untreated control...
journal_title:Urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0090-4295(99)80079-X
更新日期:1995-05-01 00:00:00
abstract:OBJECTIVE:To report a new technique to reconstruct the abdominal wall at the site of the hernia with 2 separate layers of human acellular dermal matrix (hADM). Parastomal hernia is the most commonly encountered complication of ileal conduit urinary diversion, occurring at a rate of 5%-25%. Multiple methods of parastoma...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.05.003
更新日期:2011-03-01 00:00:00