Mental vulnerability--a risk factor for ischemic heart disease.

Abstract:

OBJECTIVE:The purpose of this study is to examine whether mental vulnerability is a risk factor for the development of ischemic heart disease (IHD) after adjustment for well-established risk factors. METHODS:In three prospective cohort studies in Copenhagen County, Denmark, we recorded the level of mental vulnerability and possible risk factors to IHD at baseline. For follow-up, the sample was linked to relevant registries to identify all cases of fatal and nonfatal IHD. The relationship between mental vulnerability and IHD was examined using both Kaplan-Meir and Cox proportional hazard models adjusting for possible confounding factors. RESULTS:Mental vulnerability was significantly associated with the risk for IHD (medium mental vulnerability: hazard ratio 1.41, 95% confidence interval 1.04-1.91; and high mental vulnerability: hazard ratio 2.05; 95% confidence interval 1.46-2.88), after adjusting for confounders. CONCLUSION:Our results imply that mental vulnerability is an independent risk factor for IHD.

journal_name

J Psychosom Res

authors

Eplov LF,Jørgensen T,Birket-Smith M,Petersen J,Johansen C,Mortensen EL

doi

10.1016/j.jpsychores.2005.05.013

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

169-76

issue

2

eissn

0022-3999

issn

1879-1360

pii

S0022-3999(05)00315-6

journal_volume

60

pub_type

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