P300 amplitude in subjects with primary insomnia is modulated by their sleep quality.

Abstract:

OBJECTIVE:The hyperarousal hypothesis is evaluated while controlling the influence of the quality of sleep in the night preceding the evaluation. METHOD:Eleven primary insomniacs and 11 healthy age matched controls participated to the study. Participants filled in 2 weeks of sleep logs and self-monitored their subjective tension the evening before and the morning after each night. Afterwards, subjects were called in to the Lab for a recording session of the P300 ERP (oddball paradigm) once after a night of bad sleep quality (N-) and once after a night of good sleep quality (N+). RESULTS:The main result of the present study indicated that the P300 amplitude at Fz in insomniacs resulted higher following a N- and lower following a N+ with respect to controls. CONCLUSIONS:This result suggests that cortical hyperarousal in primary insomniacs is not a stable individual characteristic, but is associated with the poor quality of their nocturnal sleep.

journal_name

J Psychosom Res

authors

Devoto A,Violani C,Lucidi F,Lombardo C

doi

10.1016/s0022-3999(02)00579-2

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

3-10

issue

1

eissn

0022-3999

issn

1879-1360

pii

S0022399902005792

journal_volume

54

pub_type

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