Intranasal oxytocin enhances positive self-attribution in healthy men.

Abstract:

OBJECTIVE:A growing body of studies consistently demonstrates that social responsiveness toward others is influenced by the neurohormone oxytocin. However, the potential role of oxytocin for self-perception remains relatively unexplored. Thus, we investigated whether oxytocin administration influences the self-attribution of positive and negative adjectives at the early, effortful stage of self-related information processing. METHODS:Sixty healthy male participants received either 24I.U. oxytocin or a placebo in a randomized double-blind study before completing a sorting task, in which they were instructed to co-classify, as fast as possible, positive and negative adjectives into either self or non-self categories. RESULTS:Oxytocin-treated participants reported stronger positive attitudes toward themselves compared to placebo. CONCLUSIONS:The present findings demonstrate that oxytocin administration influences the early stage of self-related information processing and suggests that the oxytocinergic system might be involved in psychopathological conditions characterized by a negative representation of self.

journal_name

J Psychosom Res

authors

Colonnello V,Heinrichs M

doi

10.1016/j.jpsychores.2014.06.016

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

415-9

issue

5

eissn

0022-3999

issn

1879-1360

pii

S0022-3999(14)00250-5

journal_volume

77

pub_type

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